← All institutions
Institutional Holdings
ZBIOOwnership Summary
Institutions Holding
180
Total Shares Held
216,513,484
Total Value Held
$1,702,047,534
Quarter
2026-06-30
Active Positions
Increased Positions
59
154,776,061 shares
Decreased Positions
42
21,886,210 shares
Held Positions
16
27,424,325 shares
New Positions
38
12,426,888 shares
Sold Out Positions
25
44,919,580 shares
| Institution | Shares | Value | Change | % of Portfolio | Reported |
|---|---|---|---|---|---|
| FMR LLC | 9,506,701 | $241,280,071 | ▲ +424,701 | 0.01% | 2026-06-30 |
| SR One Capital Management, LP | 5,037,854 | $127,860,735 | Unchanged | 12.31% | 2026-06-30 |
| NEA Management Company, LLC | 4,023,219 | $102,109,298 | Unchanged | 6.43% | 2026-06-30 |
| ENAVATE SCIENCES GP, LLC | 3,919,159 | $99,468,255 | Unchanged | 28.80% | 2026-06-30 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 67,200,000 | $80,316,096 | ▲ +2,200,000 | 0.84% | 2026-06-30 |
| FEDERATED HERMES, INC. | 3,116,805 | $79,104,511 | ▼ -10,226 | 0.11% | 2026-06-30 |
| BlackRock, Inc. | 2,686,225 | $68,176,389 | ▲ +648,677 | 0.00% | 2026-06-30 |
| Capital International Investors | 2,502,912 | $63,523,907 | ▲ +68,912 | 0.01% | 2026-06-30 |
| Polar Capital Holdings Plc | 2,412,772 | $61,236,153 | ▼ -135,672 | 0.14% | 2026-06-30 |
| Royalty Pharma Sub-Manager, LLC | 2,388,150 | $60,611,247 | Unchanged | 25.05% | 2026-06-30 |
| Fairmount Funds Management LLC | 2,359,025 | $59,872,055 | Unchanged | 3.96% | 2026-06-30 |
| STATE STREET CORP | 2,055,100 | $52,158,438 | ▲ +584,177 | 0.00% | 2026-06-30 |
| NVP ASSOCIATES, LLC | 1,838,482 | $46,660,673 | Unchanged | 14.22% | 2026-06-30 |
| Context Capital Management, LLC | 35,800,000 | $42,602,000 | ▲ +6,700,000 | 0.83% | 2026-06-30 |
| WELLINGTON MANAGEMENT GROUP LLP | 1,593,819 | $40,451,126 | ▲ +347,766 | 0.01% | 2026-06-30 |
| VANGUARD CAPITAL MANAGEMENT LLC | 1,354,864 | $34,386,448 | New position | 0.00% | 2026-06-30 |
| CITADEL ADVISORS LLC | 21,931,680 | $31,704,008 | ▲ +13,804,010 | 0.00% | 2026-06-30 |
| BANK OF AMERICA CORP /DE/ | 1,231,159 | $31,246,815 | ▲ +842,812 | 0.00% | 2026-06-30 |
| GEODE CAPITAL MANAGEMENT, LLC | 882,654 | $22,406,450 | ▲ +226,869 | 0.00% | 2026-06-30 |
| ALLIANCEBERNSTEIN L.P. | 1,103,388 | $21,571,235 | ▲ +206,067 | 0.01% | 2026-06-30 |
| TWO SIGMA INVESTMENTS, LP | 815,150 | $20,688,507 | ▲ +540,094 | 0.01% | 2026-06-30 |
| EcoR1 Capital, LLC | 789,500 | $20,037,510 | Unchanged | 0.97% | 2026-06-30 |
| Woodline Partners LP | 3,090,539 | $17,950,380 | ▲ +14 | 0.06% | 2026-06-30 |
| MILLENNIUM MANAGEMENT LLC | 860,470 | $17,002,151 | ▼ -816,348 | 0.01% | 2026-06-30 |
| Balyasny Asset Management L.P. | 576,717 | $14,637,077 | ▼ -90,353 | 0.02% | 2026-06-30 |
| ArrowMark Colorado Holdings LLC | 573,318 | $14,550,811 | ▼ -85,591 | 0.61% | 2026-06-30 |
| SILVERARC CAPITAL MANAGEMENT, LLC | 509,789 | $12,938,445 | ▼ -626,146 | 1.34% | 2026-06-30 |
| Rock Springs Capital Management LP | 502,077 | $12,742,714 | Unchanged | 0.62% | 2026-06-30 |
| Pivotal bioVenture Partners Investment Advisor LLC | 490,766 | $12,455,641 | ▼ -101,225 | 4.05% | 2026-06-30 |
| NEXTBio Capital Management LP | 426,736 | $10,830,560 | Unchanged | 4.98% | 2026-06-30 |
| Vestal Point Capital, LP | 365,000 | $9,263,700 | ▲ +165,000 | 0.22% | 2026-06-30 |
| JANE STREET GROUP, LLC | 6,539,000 | $8,822,320 | ▼ -3,033,900 | 0.00% | 2026-06-30 |
| MARSHALL WACE, LLP | 323,442 | $8,208,957 | ▼ -178,486 | 0.01% | 2026-06-30 |
| JENNISON ASSOCIATES LLC | 314,049 | $7,970,564 | ▲ +64,049 | 0.00% | 2026-06-30 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 304,870 | $7,737,601 | New position | 0.00% | 2026-06-30 |
| READYSTATE ASSET MANAGEMENT LP | 6,500,000 | $7,735,000 | New position | 0.26% | 2026-06-30 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 302,085 | $7,666,917 | ▲ +77,683 | 0.00% | 2026-06-30 |
| NORTHERN TRUST CORP | 281,140 | $7,135,334 | ▲ +86,500 | 0.00% | 2026-06-30 |
| GOLDMAN SACHS GROUP INC | 271,163 | $6,882,117 | ▼ -110,298 | 0.00% | 2026-06-30 |
| VANGUARD FIDUCIARY TRUST CO | 254,623 | $6,462,332 | New position | 0.00% | 2026-06-30 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 245,100 | $6,220,638 | ▼ -20,905 | 0.00% | 2026-06-30 |
| Jefferies Financial Group Inc. | 4,998,000 | $5,979,895 | ▼ -769,947 | 0.04% | 2026-06-30 |
| SPHERA FUNDS MANAGEMENT LTD. | 230,834 | $5,858,567 | ▲ +16,500 | 0.76% | 2026-06-30 |
| Walleye Capital LLC | 209,050 | $5,305,689 | ▲ +83,818 | 0.02% | 2026-06-30 |
| Sio Capital Management, LLC | 208,557 | $5,293,177 | ▼ -123,173 | 0.88% | 2026-06-30 |
| UBS Group AG | 178,089 | $4,519,899 | ▼ -189,316 | 0.00% | 2026-06-30 |
| Voleon Capital Management LP | 167,145 | $4,242,140 | ▲ +137,533 | 0.08% | 2026-06-30 |
| CAPSTONE INVESTMENT ADVISORS, LLC | 3,500,000 | $4,165,000 | Unchanged | 0.01% | 2026-06-30 |
| BNP PARIBAS FINANCIAL MARKETS | 151,086 | $3,834,563 | ▲ +141,087 | 0.00% | 2026-06-30 |
| MORGAN STANLEY | 134,979 | $3,425,767 | ▲ +41,583 | 0.00% | 2026-06-30 |
| Squarepoint Ops LLC | 125,185 | $3,177,195 | ▲ +82,311 | 0.00% | 2026-06-30 |
| Graham Capital Management, L.P. | 2,500,000 | $2,987,337 | Unchanged | 0.05% | 2026-06-30 |
| BARCLAYS PLC | 115,965 | $2,943,193 | ▲ +86,355 | 0.00% | 2026-06-30 |
| ADVENT CAPITAL MANAGEMENT /DE/ | 2,360,000 | $2,823,314 | New position | 0.06% | 2026-06-30 |
| SEVEN GRAND MANAGERS, LLC | 100,000 | $2,538,000 | Unchanged | 0.10% | 2026-06-30 |
| Birchview Capital, LP | 93,601 | $2,375,593 | ▲ +23,601 | 1.11% | 2026-06-30 |
| Verition Fund Management LLC | 72,988 | $1,852,435 | New position | 0.01% | 2026-06-30 |
| Bank of New York Mellon Corp | 70,477 | $1,788,706 | ▲ +9,613 | 0.00% | 2026-06-30 |
| J. Goldman & Co LP | 68,232 | $1,731,728 | ▲ +31,435 | 0.04% | 2026-06-30 |
| Nuveen, LLC | 66,638 | $1,691,273 | ▼ -1,132 | 0.00% | 2026-06-30 |
| ALPS ADVISORS INC | 63,675 | $1,616,072 | ▲ +19,981 | 0.01% | 2026-06-30 |
| AGF MANAGEMENT LTD | 1,200,000 | $1,422,000 | New position | 0.01% | 2026-06-30 |
| Swiss National Bank | 53,200 | $1,350,216 | ▲ +21,600 | 0.00% | 2026-06-30 |
| Exome Asset Management LLC | 52,443 | $1,331,003 | ▼ -28,287 | 0.82% | 2026-06-30 |
| Jump Financial, LLC | 51,022 | $1,294,939 | ▼ -8,979 | 0.01% | 2026-06-30 |
| CITIGROUP INC | 49,521 | $1,256,843 | ▲ +39,633 | 0.00% | 2026-06-30 |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 48,465 | $1,230,042 | New position | 0.00% | 2026-06-30 |
| XTX Topco Ltd | 40,034 | $1,016,063 | ▲ +20,723 | 0.01% | 2026-06-30 |
| Burkehill Global Management, LP | 40,000 | $1,015,200 | Unchanged | 0.04% | 2026-06-30 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 37,790 | $959,110 | ▲ +22,267 | 0.00% | 2026-06-30 |
| Rafferty Asset Management, LLC | 37,509 | $951,978 | ▼ -10,660 | 0.00% | 2026-06-30 |
| Atom Investors LP | 37,149 | $942,842 | ▼ -69,867 | 0.08% | 2026-06-30 |
| BOOTHBAY FUND MANAGEMENT, LLC | 33,280 | $844,646 | New position | 0.01% | 2026-06-30 |
| AQR CAPITAL MANAGEMENT LLC | 31,100 | $789,319 | ▼ -19,871 | 0.00% | 2026-06-30 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 29,471 | $747,974 | ▲ +13,652 | 0.00% | 2026-06-30 |
| DEUTSCHE BANK AG TAUNUSANLAGE 12 D-60325 | 28,881 | $733,000 | ▲ +9,615 | 0.00% | 2026-06-30 |
| DCF Advisers, LLC | 28,184 | $715,310 | New position | 0.13% | 2026-06-30 |
| STATE OF WISCONSIN INVESTMENT BOARD | 26,922 | $683,280 | ▲ +6,108 | 0.00% | 2026-06-30 |
| JPMORGAN CHASE & CO | 24,445 | $660,518 | ▼ -664 | 0.00% | 2026-06-30 |
| WELLS FARGO & COMPANY/MN | 25,995 | $659,753 | ▲ +17,110 | 0.00% | 2026-06-30 |
| VANGUARD ASSET MANAGEMENT, Ltd | 20,623 | $523,412 | New position | 0.00% | 2026-06-30 |
| Legal & General Group Plc | 20,023 | $508,182 | ▲ +9,591 | 0.00% | 2026-06-30 |
| Invesco Ltd. | 18,954 | $481,053 | New position | 0.00% | 2026-06-30 |
| China Universal Asset Management Co., Ltd. | 18,848 | $478,362 | ▲ +5,322 | 0.03% | 2026-06-30 |
| PROFUND ADVISORS LLC | 18,838 | $478,108 | ▼ -2,578 | 0.01% | 2026-06-30 |
| ALLSTATE CORP | 18,241 | $462,957 | ▲ +18 | 0.00% | 2026-06-30 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 17,423 | $442,936 | ▲ +3,037 | 0.00% | 2026-06-30 |
| Y-Intercept (Hong Kong) Ltd | 17,332 | $439,886 | New position | 0.01% | 2026-06-30 |
| MetLife Investment Management, LLC | 17,041 | $432,501 | ▲ +4,132 | 0.00% | 2026-06-30 |
| Virtus Investment Advisers, LLC | 16,525 | $419,405 | ▲ +9,808 | 0.10% | 2026-06-30 |
| Point72 Asset Management, L.P. | 16,136 | $409,532 | New position | 0.00% | 2026-06-30 |
| Vanguard Global Advisers, LLC | 15,332 | $389,126 | New position | 0.00% | 2026-06-30 |
| NORDEA INVESTMENT MANAGEMENT AB | 15,050 | $382,872 | New position | 0.00% | 2026-06-30 |
| Brevan Howard Capital Management LP | 14,674 | $372,426 | New position | 0.00% | 2026-06-30 |
| Engineers Gate Manager LP | 12,980 | $329,432 | New position | 0.00% | 2026-06-30 |
| Russell Investments Group, Ltd. | 12,740 | $323,341 | ▲ +10,019 | 0.00% | 2026-06-30 |
| Creative Planning | 11,723 | $297,530 | ▼ -935 | 0.00% | 2026-06-30 |
| VARCOV Co. | 10,505 | $266,617 | New position | 0.10% | 2026-06-30 |
| NEW YORK STATE COMMON RETIREMENT FUND | 10,300 | $261,414 | ▲ +4,100 | 0.00% | 2026-06-30 |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 9,053 | $229,765 | New position | 0.00% | 2026-06-30 |
| Scientech Research LLC | 9,028 | $229,131 | ▼ -3,924 | 0.19% | 2026-06-30 |
| DIMENSIONAL FUND ADVISORS LP | 8,874 | $225,222 | New position | 0.00% | 2026-06-30 |
| Quantinno Capital Management LP | 8,581 | $217,786 | ▼ -12,545 | 0.00% | 2026-06-30 |
| State of New Jersey Common Pension Fund D | 8,571 | $217,532 | New position | 0.00% | 2026-06-30 |
| Police & Firemen's Retirement System of New Jersey | 8,418 | $213,649 | ▲ +2,055 | 0.00% | 2026-06-30 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 8,032 | $203,852 | New position | 0.00% | 2026-06-30 |
| Jupiter Topco LLC | 7,900 | $200,581 | New position | 0.00% | 2026-06-30 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 7,563 | $191,949 | ▲ +786 | 0.00% | 2026-06-30 |
| KLP KAPITALFORVALTNING AS | 6,100 | $154,818 | ▲ +2,700 | 0.00% | 2026-06-30 |
| PNC Financial Services Group, Inc. | 4,739 | $120,277 | ▼ -28 | 0.00% | 2026-06-30 |
| Vanguard Investments Australia, Ltd. | 4,199 | $106,571 | New position | 0.00% | 2026-06-30 |
| Mirae Asset Global Investments Co., Ltd. | 2,824 | $71,673 | ▲ +24 | 0.00% | 2026-06-30 |
| SIMPLEX TRADING, LLC | 2,600 | $65,988 | ▲ +1,100 | 0.00% | 2026-06-30 |
| Ameritas Investment Partners, Inc. | 2,586 | $65,633 | ▲ +662 | 0.00% | 2026-06-30 |
| TOUNJIAN ADVISORY PARTNERS, LLC | 2,500 | $63,450 | New position | 0.03% | 2026-06-30 |
| Quantbot Technologies LP | 1,928 | $48,933 | ▲ +1,672 | 0.00% | 2026-06-30 |
| Tower Research Capital LLC (TRC) | 1,286 | $32,639 | ▼ -5,949 | 0.00% | 2026-06-30 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,226,928 | $31,141 | ▲ +869,662 | 0.00% | 2026-06-30 |
| GF FUND MANAGEMENT CO. LTD. | 1,138 | $28,882 | ▼ -67 | 0.00% | 2026-06-30 |
| SIGNATUREFD, LLC | 1,134 | $28,781 | ▲ +764 | 0.00% | 2026-06-30 |
| ROYAL BANK OF CANADA | 847 | $21,000 | New position | 0.00% | 2026-06-30 |
| NISA INVESTMENT ADVISORS, LLC | 651 | $16,522 | ▼ -1,764 | 0.00% | 2026-06-30 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 539 | $13,680 | New position | 0.00% | 2026-06-30 |
| Silver Grove Financial Group, Inc. | 538 | $13,654 | New position | 0.01% | 2026-06-30 |
| Larson Financial Group LLC | 454 | $11,523 | ▲ +161 | 0.00% | 2026-06-30 |
| Global Retirement Partners, LLC | 420 | $10,660 | ▲ +409 | 0.00% | 2026-06-30 |
| HARBOUR INVESTMENTS, INC. | 370 | $9,391 | ▼ -1,000 | 0.00% | 2026-06-30 |
| GROUP ONE TRADING LLC | 345 | $8,756 | ▼ -355 | 0.00% | 2026-06-30 |
| US BANCORP DE U.S. BANCORP | 304 | $7,716 | ▼ -690 | 0.00% | 2026-06-30 |
| OSAIC HOLDINGS, INC. | 295 | $7,487 | ▼ -382 | 0.00% | 2026-06-30 |
| J.Safra Asset Management Corp | 224 | $5,685 | ▼ -46 | 0.00% | 2026-06-30 |
| iA Global Asset Management Inc. | 215,130 | $5,460 | ▼ -700 | 0.06% | 2026-06-30 |
| GAMMA Investing LLC | 195 | $4,949 | ▼ -50 | 0.00% | 2026-06-30 |
| EverSource Wealth Advisors, LLC | 162 | $4,112 | ▲ +64 | 0.00% | 2026-06-30 |
| Integrated Wealth Concepts LLC | 138 | $3,502 | New position | 0.00% | 2026-06-30 |
| Arax Advisory Partners | 104 | $2,640 | New position | 0.00% | 2026-06-30 |
| Sterling Capital Management LLC | 100 | $2,538 | ▼ -679 | 0.00% | 2026-06-30 |
| Bare Financial Services, Inc | 95 | $2,412 | ▲ +81 | 0.00% | 2026-06-30 |
| Torren Management, LLC | 95 | $2,411 | Unchanged | 0.00% | 2026-06-30 |
| CSM Advisors, LLC | 67,622 | $1,716 | New position | 0.04% | 2026-06-30 |
| Physician Wealth Advisors, Inc. | 67 | $1,701 | ▼ -25 | 0.00% | 2026-06-30 |
| Ameritas Advisory Services, LLC | 42 | $1,066 | ▲ +36 | 0.00% | 2026-06-30 |
| Fortitude Family Office, LLC | 29 | $736 | New position | 0.00% | 2026-06-30 |
| Cornerstone Financial Management LLC | 26 | $660 | Unchanged | 0.00% | 2026-06-30 |
| ROTHSCHILD INVESTMENT LLC | 20 | $508 | ▼ -1 | 0.00% | 2026-06-30 |
| CoreCap Advisors, LLC | 12 | $305 | New position | 0.00% | 2026-06-30 |
| HRT FINANCIAL LP | 8,879 | $225 | ▼ -16,870 | 0.00% | 2026-06-30 |
| SG Americas Securities, LLC | 8,442 | $214 | New position | 0.00% | 2026-06-30 |
| Caitong International Asset Management Co., Ltd | 2 | $51 | ▼ -58 | 0.00% | 2026-06-30 |
| Essential Partners LLC | 2 | $51 | Unchanged | 0.00% | 2026-06-30 |
| Allworth Financial LP | 1 | $26 | ▼ -25 | 0.00% | 2026-06-30 |
| Freestone Grove Partners LP | 1 | $25 | New position | 0.00% | 2026-06-30 |
| Hughes Financial Services, LLC | 1 | $25 | New position | 0.00% | 2026-06-30 |
| Pacer Advisors, Inc. | 626 | $16 | New position | 0.00% | 2026-06-30 |
| Covestor Ltd | 22 | $1 | ▲ +16 | 0.00% | 2026-06-30 |
| HIGHBRIDGE CAPITAL MANAGEMENT LLC | 0 | $0 | Sold out | 2026-06-30 | |
| BRAIDWELL LP | 0 | $0 | Sold out | 2026-06-30 | |
| Monashee Investment Management LLC | 0 | $0 | Sold out | 2026-06-30 | |
| D. E. Shaw & Co., Inc. | 0 | $0 | Sold out | 2026-06-30 | |
| Calamos Advisors LLC | 0 | $0 | Sold out | 2026-06-30 | |
| Maven Securities LTD | 0 | $0 | Sold out | 2026-06-30 | |
| GREAT POINT PARTNERS LLC | 0 | $0 | Sold out | 2026-06-30 | |
| ARISTEIA CAPITAL, L.L.C. | 0 | $0 | Sold out | 2026-06-30 | |
| SEB Asset Management AB | 0 | $0 | Sold out | 2026-06-30 | |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 0 | $0 | Sold out | 2026-06-30 | |
| DAFNA Capital Management LLC | 0 | $0 | Sold out | 2026-06-30 | |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 0 | $0 | Sold out | 2026-06-30 | |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0 | $0 | Sold out | 2026-06-30 | |
| Aquatic Capital Management LLC | 0 | $0 | Sold out | 2026-06-30 | |
| Schonfeld Strategic Advisors LLC | 0 | $0 | Sold out | 2026-06-30 | |
| Corient Private Wealth LP | 0 | $0 | Sold out | 2026-06-30 | |
| PRELUDE CAPITAL MANAGEMENT, LLC | 0 | $0 | Sold out | 2026-06-30 | |
| FOX RUN MANAGEMENT, L.L.C. | 0 | $0 | Sold out | 2026-06-30 | |
| SEI INVESTMENTS CO | 0 | $0 | Sold out | 2026-06-30 | |
| STRS OHIO | 0 | $0 | Sold out | 2026-06-30 | |
| FIFTH THIRD BANCORP | 0 | $0 | Sold out | 2026-06-30 | |
| SBI Securities Co., Ltd. | 0 | $0 | Sold out | 2026-06-30 | |
| MAI Capital Management | 0 | $0 | Sold out | 2026-06-30 | |
| Stone House Investment Management, LLC | 0 | $0 | Sold out | 2026-06-30 | |
| True Wealth Design, LLC | 0 | $0 | Sold out | 2026-06-30 |