NEXTBio Capital Management LP
CIK 0002038158
Annualised vol
12.641422%
Beta
0.091137
HHI
742.679077
Top-10 weight
77.704863%
VaR 95%
1.222997%
VaR 99%
2.768256%
Max drawdown
35.348527%
Matched value
90.570954%
Returns of reported holdings
Loading returns…
Position changes vs prior quarter
What the latest 13F shows bought and sold against the quarter before, by share count.
| Ticker | Change | Shares now | Shares before | Share change % | Value now ($) |
|---|---|---|---|---|---|
| PTGX | REDUCED | 219,333 | 229,619 | -4.48% | 26,885,839 |
| STTK | ADDED | 3,727,348 | 3,149,907 | 18.33% | 25,867,795 |
| CMPS | REDUCED | 1,775,759 | 2,021,407 | -12.15% | 25,126,990 |
| GPCR | ADDED | 312,496 | 133,239 | 134.54% | 16,771,660 |
| VOR | REDUCED | 889,164 | 999,967 | -11.08% | 16,369,509 |
| RYTM | ADDED | 131,758 | 126,078 | 4.51% | 14,629,091 |
| XENE | UNCHANGED | 183,225 | 183,225 | 0.0% | 11,059,461 |
| ZBIO | UNCHANGED | 426,736 | 426,736 | 0.0% | 10,830,560 |
| ORIC | ADDED | 706,124 | 523,619 | 34.85% | 7,647,323 |
| CBIO | UNCHANGED | 372,856 | 372,856 | 0.0% | 6,711,408 |
| PCVX | ADDED | 107,223 | 95,223 | 12.6% | 6,232,873 |
| COGT | REDUCED | 131,075 | 131,188 | -0.09% | 5,072,603 |
| VSTM | UNCHANGED | 1,306,800 | 1,306,800 | 0.0% | 4,991,976 |
| IRON | UNCHANGED | 52,655 | 52,655 | 0.0% | 3,851,187 |
| PHVS | NEW | 108,055 | - | - | 3,736,542 |
| ZLAB | UNCHANGED | 183,362 | 183,362 | 0.0% | 3,483,878 |
| BIOA | NEW | 100,732 | - | - | 2,468,941 |
| LBRX | NEW | 68,249 | - | - | 2,215,021 |
| EVMN | REDUCED | 119,063 | 184,063 | -35.31% | 1,582,347 |
| ACET | UNCHANGED | 157,827 | 157,827 | 0.0% | 1,363,625 |
| CMPX | CLOSED OUT | 0 | 848,204 | -100.0% | 0 |
| OCS | CLOSED OUT | 0 | 149,592 | -100.0% | 0 |
| SMMT | CLOSED OUT | 0 | 89,717 | -100.0% | 0 |
Holdings (latest quarter)
| Ticker | Change | Issuer | Class | CUSIP | Value ($) | Weight % | Shares |
|---|---|---|---|---|---|---|---|
| PTGX | REDUCED | PROTAGONIST THERAPEUTICS INC | COM | 74366E102 | 26,885,839 | 12.37 | 219333.0 |
| STTK | ADDED | SHATTUCK LABS INC | COM | 82024L103 | 25,867,795 | 11.9 | 3727348.0 |
| CMPS | REDUCED | COMPASS PATHWAYS PLC | SPONSORED ADS | 20451W101 | 25,126,990 | 11.56 | 1775759.0 |
| GPCR | ADDED | STRUCTURE THERAPEUTICS INC | SPONSORED ADS | 86366E106 | 16,771,660 | 7.71 | 312496.0 |
| VOR | REDUCED | VOR BIOPHARMA INC | COM NEW | 929033207 | 16,369,509 | 7.53 | 889164.0 |
| RYTM | ADDED | RHYTHM PHARMACEUTICALS INC | COM | 76243J105 | 14,629,091 | 6.73 | 131758.0 |
| - | PALVELLA THERAPEUTICS INC NE | COM | 697947109 | 13,739,893 | 6.32 | 89909.0 | |
| XENE | UNCHANGED | XENON PHARMACEUTICALS INC | COM | 98420N105 | 11,059,461 | 5.09 | 183225.0 |
| ZBIO | UNCHANGED | ZENAS BIOPHARMA INC | COM | 98937L105 | 10,830,560 | 4.98 | 426736.0 |
| ORIC | ADDED | ORIC PHARMACEUTICALS INC | COM | 68622P109 | 7,647,323 | 3.52 | 706124.0 |
| - | INVENTIVA SA | ADS | 46124U107 | 6,758,580 | 3.11 | 1787984.0 | |
| CBIO | UNCHANGED | CRESCENT BIOPHARMA INC. | COM | G2545C104 | 6,711,408 | 3.09 | 372856.0 |
| PCVX | ADDED | VAXCYTE INC | COM | 92243G108 | 6,232,873 | 2.87 | 107223.0 |
| COGT | REDUCED | COGENT BIOSCIENCES INC | COM | 19240Q201 | 5,072,603 | 2.33 | 131075.0 |
| VSTM | UNCHANGED | VERASTEM INC | COM NEW | 92337C203 | 4,991,976 | 2.3 | 1306800.0 |
| IRON | UNCHANGED | DISC MEDICINE INC | COM | 254604101 | 3,851,187 | 1.77 | 52655.0 |
| PHVS | NEW | PHARVARIS N V | COM | N69605108 | 3,736,542 | 1.72 | 108055.0 |
| ZLAB | UNCHANGED | ZAI LAB LTD | ADR | 98887Q104 | 3,483,878 | 1.6 | 183362.0 |
| BIOA | NEW | BIOAGE LABS INC | COM | 09077V100 | 2,468,941 | 1.14 | 100732.0 |
| LBRX | NEW | LB PHARMACEUTICALS INC | COM SHS | 50180M108 | 2,215,021 | 1.02 | 68249.0 |
| EVMN | REDUCED | EVOMMUNE INC | COM SHS | 30054Y107 | 1,582,347 | 0.73 | 119063.0 |
| ACET | UNCHANGED | ADICET BIO INC | COM NEW | 007002207 | 1,363,625 | 0.63 | 157827.0 |
Quarterly portfolios
| Period | Filed | Value ($) | Positions | Vol % | Beta | Max DD % |
|---|---|---|---|---|---|---|
| 2026-06-30 | 2026-08-14 | 217,397,102 | 22 | 12.641422 | 0.091137 | 35.348527 |
| 2026-03-31 | 2026-05-14 | 215,370,002 | 24 | 11.13178 | 0.085889 | 25.262749 |
| 2025-12-31 | 2026-02-13 | 170,491,823 | 23 | 11.761749 | 0.088263 | 24.215417 |