SILVERARC CAPITAL MANAGEMENT, LLC
CIK 0001816307
Annualised vol
12.246826%
Beta
0.129397
HHI
275.043027
Top-10 weight
42.319598%
VaR 95%
1.107894%
VaR 99%
2.392078%
Max drawdown
30.552108%
Matched value
85.36272%
Returns of reported holdings
Loading returns…
Position changes vs prior quarter
What the latest 13F shows bought and sold against the quarter before, by share count.
| Ticker | Change | Shares now | Shares before | Share change % | Value now ($) |
|---|---|---|---|---|---|
| ASND | ADDED | 206,234 | 124,658 | 65.44% | 55,006,732 |
| CELC | ADDED | 500,996 | 412,403 | 21.48% | 52,414,202 |
| COGT | REDUCED | 1,280,707 | 1,314,189 | -2.55% | 49,563,361 |
| URGN | REDUCED | 1,301,979 | 1,503,045 | -13.38% | 47,912,827 |
| IMNM | ADDED | 2,017,009 | 1,850,278 | 9.01% | 42,740,421 |
| SNDX | ADDED | 1,907,990 | 1,208,987 | 57.82% | 41,708,661 |
| RYTM | ADDED | 311,461 | 306,000 | 1.78% | 34,581,515 |
| GLUE | REDUCED | 1,408,295 | 2,002,040 | -29.66% | 34,080,739 |
| ORKA | ADDED | 352,802 | 150,908 | 133.79% | 33,576,166 |
| ELVN | NEW | 489,382 | - | - | 24,836,137 |
| IMVT | ADDED | 619,096 | 414,236 | 49.45% | 23,853,769 |
| ERAS | REDUCED | 1,263,026 | 1,851,812 | -31.8% | 23,138,636 |
| SGMT | NEW | 2,927,698 | - | - | 22,631,106 |
| KOD | REDUCED | 546,256 | 991,930 | -44.93% | 21,282,134 |
| DFTX | NEW | 400,000 | - | - | 18,816,000 |
| VCYT | ADDED | 318,001 | 179,700 | 76.96% | 18,676,199 |
| ORIC | ADDED | 1,421,473 | 1,100,010 | 29.22% | 15,394,553 |
| GH | ADDED | 99,826 | 98,514 | 1.33% | 14,976,895 |
| CCCC | ADDED | 3,032,060 | 1,911,785 | 58.6% | 14,159,720 |
| ZBIO | REDUCED | 509,789 | 1,135,935 | -55.12% | 12,938,445 |
| TRVI | ADDED | 678,095 | 511,127 | 32.67% | 12,646,472 |
| HLXC | REDUCED | 1,177,821 | 1,208,986 | -2.58% | 12,532,015 |
| MANE | NEW | 95,000 | - | - | 11,679,300 |
| XENE | REDUCED | 186,821 | 197,759 | -5.53% | 11,276,516 |
| BIIB | REDUCED | 48,101 | 50,967 | -5.62% | 10,392,702 |
| ACRS | NEW | 1,946,482 | - | - | 10,296,890 |
| CERS | ADDED | 3,472,737 | 3,176,547 | 9.32% | 10,140,392 |
| AVTX | NEW | 500,402 | - | - | 9,247,429 |
| BNTC | REDUCED | 679,826 | 717,725 | -5.28% | 9,096,072 |
| PCVX | ADDED | 145,000 | 144,981 | 0.01% | 8,428,850 |
| WGS | NEW | 122,269 | - | - | 8,393,767 |
| SVRA | REDUCED | 1,355,459 | 1,430,982 | -5.28% | 8,349,627 |
| OVID | ADDED | 3,101,129 | 1,000,000 | 210.11% | 8,342,037 |
| CMPS | ADDED | 503,382 | 300,000 | 67.79% | 7,122,855 |
| CGEN | REDUCED | 3,184,257 | 3,315,845 | -3.97% | 6,814,310 |
| SLDB | NEW | 668,450 | - | - | 6,677,816 |
| IBIO | ADDED | 3,520,490 | 226,000 | 1457.74% | 6,160,858 |
| IRON | REDUCED | 82,800 | 196,028 | -57.76% | 6,055,992 |
| ALKS | REDUCED | 113,494 | 460,314 | -75.34% | 5,946,518 |
| SYRE | REDUCED | 59,959 | 186,618 | -67.87% | 5,323,160 |
| ARTV | NEW | 525,000 | - | - | 5,092,500 |
| CTNM | REDUCED | 296,135 | 301,729 | -1.85% | 4,853,653 |
| RACC | NEW | 360,000 | - | - | 3,852,000 |
| ABEO | REDUCED | 610,407 | 648,942 | -5.94% | 3,772,315 |
| INSM | REDUCED | 34,438 | 35,850 | -3.94% | 3,671,780 |
| KPTI | NEW | 297,460 | - | - | 2,906,184 |
| KYMR | NEW | 25,000 | - | - | 2,866,750 |
| CAMP | UNCHANGED | 653,594 | 653,594 | 0.0% | 2,856,206 |
| ELUT | REDUCED | 2,192,980 | 2,498,020 | -12.21% | 2,148,243 |
| RVMD | NEW | 10,000 | - | - | 1,872,800 |
| SION | ADDED | 42,478 | 39,417 | 7.77% | 1,868,607 |
| ABSI | NEW | 157,600 | - | - | 1,826,584 |
| TELA | REDUCED | 2,137,201 | 2,259,312 | -5.4% | 1,602,901 |
| FULC | REDUCED | 391,900 | 811,849 | -51.73% | 1,434,354 |
| GUTS | REDUCED | 1,637,976 | 1,701,625 | -3.74% | 1,301,208 |
| CBIO | REDUCED | 59,104 | 130,500 | -54.71% | 1,063,872 |
| CLRB | NEW | 321,728 | - | - | 894,404 |
| FHTX | NEW | 45,975 | - | - | 224,358 |
| RCKT | UNCHANGED | 104,828 | 104,828 | 0.0% | 356 |
| CMPX | CLOSED OUT | 0 | 1,031,449 | -100.0% | 0 |
| NMRA | CLOSED OUT | 0 | 818,156 | -100.0% | 0 |
| CLYM | CLOSED OUT | 0 | 684,908 | -100.0% | 0 |
| ZURA | CLOSED OUT | 0 | 560,651 | -100.0% | 0 |
| ANNX | CLOSED OUT | 0 | 496,461 | -100.0% | 0 |
| RADX | CLOSED OUT | 0 | 187,406 | -100.0% | 0 |
| CLDX | CLOSED OUT | 0 | 178,378 | -100.0% | 0 |
| NXTC | CLOSED OUT | 0 | 176,057 | -100.0% | 0 |
| REPL | CLOSED OUT | 0 | 171,936 | -100.0% | 0 |
| CGON | CLOSED OUT | 0 | 166,349 | -100.0% | 0 |
| GENB | CLOSED OUT | 0 | 100,000 | -100.0% | 0 |
| CYTK | CLOSED OUT | 0 | 71,203 | -100.0% | 0 |
| MNPR | CLOSED OUT | 0 | 43,488 | -100.0% | 0 |
| EWTX | CLOSED OUT | 0 | 42,615 | -100.0% | 0 |
| AARD | CLOSED OUT | 0 | 33,684 | -100.0% | 0 |
Holdings (latest quarter)
| Ticker | Change | Issuer | Class | CUSIP | Value ($) | Weight % | Shares |
|---|---|---|---|---|---|---|---|
| ASND | ADDED | ASCENDIS PHARMA A/S | ORD SHS | K08588103 | 55,006,732 | 5.72 | 206234.0 |
| CELC | ADDED | CELCUITY INC | COM | 15102K100 | 52,414,202 | 5.45 | 500996.0 |
| COGT | REDUCED | COGENT BIOSCIENCES INC | COM | 19240Q201 | 49,563,361 | 5.15 | 1280707.0 |
| URGN | REDUCED | UROGEN PHARMA LTD | COM | M96088105 | 47,912,827 | 4.98 | 1301979.0 |
| IMNM | ADDED | IMMUNOME INC | COM | 45257U108 | 42,740,421 | 4.44 | 2017009.0 |
| - | DIANTHUS THERAPEUTICS INC | COM | 252828108 | 38,017,200 | 3.95 | 390000.0 | |
| RYTM | ADDED | RHYTHM PHARMACEUTICALS INC | COM | 76243J105 | 34,581,515 | 3.59 | 311461.0 |
| ORKA | ADDED | ORUKA THERAPEUTICS INC | COM | 687604108 | 33,576,166 | 3.49 | 352802.0 |
| GLUE | REDUCED | MONTE ROSA THERAPEUTICS INC | COM | 61225M102 | 26,820,739 | 2.79 | 1108295.0 |
| SNDX | ADDED | SYNDAX PHARMACEUTICALS INC | COM | 87164F105 | 26,546,565 | 2.76 | 1214390.0 |
| ELVN | NEW | ENLIVEN THERAPEUTICS INC | COM | 29337E102 | 24,836,137 | 2.58 | 489382.0 |
| IMVT | ADDED | IMMUNOVANT INC | COM | 45258J102 | 23,853,769 | 2.48 | 619096.0 |
| ERAS | REDUCED | ERASCA INC | COM | 29479A108 | 23,138,636 | 2.4 | 1263026.0 |
| SGMT | NEW | SAGIMET BIOSCIENCES INC | COM SER A | 786700104 | 22,631,106 | 2.35 | 2927698.0 |
| - | ABIVAX SA | SPONSORED ADS | 00370M103 | 22,599,963 | 2.35 | 169593.0 | |
| - | PRAXIS PRECISION MEDICINES I | COM NEW | 74006W207 | 21,988,672 | 2.29 | 65679.0 | |
| KOD | REDUCED | KODIAK SCIENCES INC | COM | 50015M109 | 21,282,134 | 2.21 | 546256.0 |
| - | ARK ETF TR | PUT | 00214Q952 | 21,030,000 | 2.19 | 500000.0 | |
| DFTX | NEW | DEFINIUM THERAPEUTICS INC | COM SHS | 24477V105 | 18,816,000 | 1.96 | 400000.0 |
| VCYT | ADDED | VERACYTE INC | COM | 92337F107 | 18,676,199 | 1.94 | 318001.0 |
| SNDX | ADDED | SYNDAX PHARMACEUTICALS INC | CALL | 87164F905 | 15,162,096 | 1.58 | 693600.0 |
| GH | ADDED | GUARDANT HEALTH INC | COM | 40131M109 | 14,976,895 | 1.56 | 99826.0 |
| CCCC | ADDED | C4 THERAPEUTICS INC | COM STK | 12529R107 | 14,159,720 | 1.47 | 3032060.0 |
| ZBIO | REDUCED | ZENAS BIOPHARMA INC | COM | 98937L105 | 12,938,445 | 1.34 | 509789.0 |
| TRVI | ADDED | TREVI THERAPEUTICS INC | COM | 89532M101 | 12,646,472 | 1.31 | 678095.0 |
| HLXC | REDUCED | HELIX ACQUISITION CORP III | USD CL A ORD SHS | G4444S107 | 12,532,015 | 1.3 | 1177821.0 |
| - | ALX ONCOLOGY HLDGS INC | COM | 00166B105 | 11,891,647 | 1.24 | 5744757.0 | |
| MANE | NEW | VERADERMICS INC | COMMON STOCK | 922967104 | 11,679,300 | 1.21 | 95000.0 |
| XENE | REDUCED | XENON PHARMACEUTICALS INC | COM | 98420N105 | 11,276,516 | 1.17 | 186821.0 |
| - | AVALYN PHARMACEUTICALS INC | COM SHS | 05348Y105 | 10,879,632 | 1.13 | 330487.0 | |
| BIIB | REDUCED | BIOGEN INC | COM | 09062X103 | 10,392,702 | 1.08 | 48101.0 |
| ACRS | NEW | ACLARIS THERAPEUTICS INC | COM | 00461U105 | 10,296,890 | 1.07 | 1946482.0 |
| CERS | ADDED | CERUS CORP | COM | 157085101 | 10,140,392 | 1.05 | 3472737.0 |
| AVTX | NEW | AVALO THERAPEUTICS INC | COM NEW | 05338F306 | 9,247,429 | 0.96 | 500402.0 |
| BNTC | REDUCED | BENITEC BIOPHARMA INC | COM NEW | 08205P209 | 9,096,072 | 0.95 | 679826.0 |
| PCVX | ADDED | VAXCYTE INC | COM | 92243G108 | 8,428,850 | 0.88 | 145000.0 |
| WGS | NEW | GENEDX HOLDINGS CORP | COM CL A | 81663L200 | 8,393,767 | 0.87 | 122269.0 |
| SVRA | REDUCED | SAVARA INC | COM | 805111101 | 8,349,627 | 0.87 | 1355459.0 |
| OVID | ADDED | OVID THERAPEUTICS INC | COM | 690469101 | 8,342,037 | 0.87 | 3101129.0 |
| ORIC | ADDED | ORIC PHARMACEUTICALS INC | COM | 68622P109 | 8,001,995 | 0.83 | 738873.0 |
| ORIC | ADDED | ORIC PHARMACEUTICALS INC | CALL | 68622P909 | 7,392,558 | 0.77 | 682600.0 |
| GLUE | REDUCED | MONTE ROSA THERAPEUTICS INC | CALL | 61225M902 | 7,260,000 | 0.75 | 300000.0 |
| CMPS | ADDED | COMPASS PATHWAYS PLC | SPONSORED ADS | 20451W101 | 7,122,855 | 0.74 | 503382.0 |
| CGEN | REDUCED | COMPUGEN LTD | ORD | M25722105 | 6,814,310 | 0.71 | 3184257.0 |
| SLDB | NEW | SOLID BIOSCIENCES INC | COM NEW | 83422E204 | 6,677,816 | 0.69 | 668450.0 |
| - | ABIVAX SA | CALL | 00370M903 | 6,663,000 | 0.69 | 50000.0 | |
| IBIO | ADDED | IBIO INC | COM NEW | 451033708 | 6,160,858 | 0.64 | 3520490.0 |
| IRON | REDUCED | DISC MEDICINE INC | COM | 254604101 | 6,055,992 | 0.63 | 82800.0 |
| ALKS | REDUCED | ALKERMES PLC | SHS | G01767105 | 5,946,518 | 0.62 | 113494.0 |
| SYRE | REDUCED | SPYRE THERAPEUTICS INC | COM NEW | 00773J202 | 5,323,160 | 0.55 | 59959.0 |
| ARTV | NEW | ARTIVA BIOTHERAPEUTICS INC | COM | 04317A107 | 5,092,500 | 0.53 | 525000.0 |
| CTNM | REDUCED | CONTINEUM THERAPEUTICS INC | CL A | 21217B100 | 4,853,653 | 0.5 | 296135.0 |
| - | UNIQURE NV | SHS | N90064101 | 4,836,300 | 0.5 | 105000.0 | |
| RACC | NEW | RESEARCH ALLIANCE CORP III | ORD SHS CL A | G75226103 | 3,852,000 | 0.4 | 360000.0 |
| ABEO | REDUCED | ABEONA THERAPEUTICS INC | COM NEW | 00289Y206 | 3,772,315 | 0.39 | 610407.0 |
| INSM | REDUCED | INSMED INC | COM PAR $.01 | 457669307 | 3,671,780 | 0.38 | 34438.0 |
| KPTI | NEW | KARYOPHARM THERAPEUTICS INC | COM NEW | 48576U205 | 2,906,184 | 0.3 | 297460.0 |
| KYMR | NEW | KYMERA THERAPEUTICS INC | PUT | 501575954 | 2,866,750 | 0.3 | 25000.0 |
| CAMP | UNCHANGED | CAMP4 THERAPEUTICS CORP | COM | 13463J101 | 2,856,206 | 0.3 | 653594.0 |
| ELUT | REDUCED | ELUTIA INC | CL A COM | 05479K106 | 2,148,243 | 0.22 | 2192980.0 |
| RVMD | NEW | REVOLUTION MEDICINES INC | COM | 76155X100 | 1,872,800 | 0.19 | 10000.0 |
| SION | ADDED | SIONNA THERAPEUTICS INC | COM | 829401108 | 1,868,607 | 0.19 | 42478.0 |
| ABSI | NEW | ABSCI CORPORATION | PUT | 00091E959 | 1,826,584 | 0.19 | 157600.0 |
| TELA | REDUCED | TELA BIO INC | COM | 872381108 | 1,602,901 | 0.17 | 2137201.0 |
| - | ACHIEVE LIFE SCIENCE INC | COM | 004468500 | 1,483,472 | 0.15 | 227178.0 | |
| FULC | REDUCED | FULCRUM THERAPEUTICS INC | CALL | 359616909 | 1,434,354 | 0.15 | 391900.0 |
| GUTS | REDUCED | FRACTYL HEALTH INC | COM | 35168W103 | 1,301,208 | 0.14 | 1637976.0 |
| - | CONNECT BIOPHARMA HLDGS LTD | SHS | G23549101 | 1,297,100 | 0.13 | 545000.0 | |
| CBIO | REDUCED | CRESCENT BIOPHARMA INC. | COM | G2545C104 | 1,063,872 | 0.11 | 59104.0 |
| CLRB | NEW | CELLECTAR BIOSCIENCES INC | COM NEW | 15117F880 | 894,404 | 0.09 | 321728.0 |
| FHTX | NEW | FOGHORN THERAPEUTICS INC | COM | 344174107 | 224,358 | 0.02 | 45975.0 |
| - | ADAGIO MED HLDGS INC | COM | 00534B100 | 146,193 | 0.02 | 224360.0 | |
| RCKT | UNCHANGED | ROCKET PHARMACEUTICALS INC | *W EXP 09/02/202 | 77313F114 | 356 | 0.0 | 104828.0 |
Quarterly portfolios
| Period | Filed | Value ($) | Positions | Vol % | Beta | Max DD % |
|---|---|---|---|---|---|---|
| 2026-06-30 | 2026-08-13 | 962,154,050 | 73 | 12.246826 | 0.129397 | 30.552108 |
| 2026-03-31 | 2026-05-14 | 979,812,415 | 73 | 10.334762 | 0.108245 | 27.56054 |
| 2025-12-31 | 2026-02-12 | 720,050,731 | 68 | 9.90443 | 0.132376 | 24.427671 |
| 2025-09-30 | 2025-11-12 | 741,600,759 | 82 | 7.726648 | 0.125124 | 18.18841 |
| 2025-03-31 | 2025-05-14 | 488,995,340 | 69 | 6.886483 | 0.135244 | 12.026005 |
| 2024-12-31 | 2025-02-14 | 457,181,067 | 61 | 8.221366 | 0.134455 | 21.719628 |