← All institutions
Institutional Holdings
SIONOwnership Summary
Institutions Holding
156
Total Shares Held
48,267,744
Total Value Held
$2,096,627,832
Quarter
2026-06-30
Active Positions
Increased Positions
54
11,138,738 shares
Decreased Positions
38
8,030,649 shares
Held Positions
15
26,207,496 shares
New Positions
43
2,890,861 shares
Sold Out Positions
6
38,491 shares
| Institution | Shares | Value | Change | % of Portfolio | Reported |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 9,905,045 | $435,722,930 | Unchanged | 3.79% | 2026-06-30 |
| TPG GP A, LLC | 6,494,962 | $285,713,378 | Unchanged | 5.71% | 2026-06-30 |
| VIKING GLOBAL INVESTORS LP | 3,195,181 | $140,556,012 | Unchanged | 0.40% | 2026-06-30 |
| Atlas Venture Life Science Advisors, LLC | 2,995,602 | $131,776,532 | Unchanged | 14.95% | 2026-06-30 |
| ORBIMED ADVISORS LLC | 2,555,877 | $112,433,029 | ▼ -974,825 | 2.08% | 2026-06-30 |
| ENAVATE SCIENCES GP, LLC | 2,478,030 | $109,008,540 | Unchanged | 31.56% | 2026-06-30 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,600,000 | $70,384,000 | ▲ +1,450,000 | 0.10% | 2026-06-30 |
| BlackRock, Inc. | 1,474,769 | $64,875,089 | ▲ +178,902 | 0.00% | 2026-06-30 |
| JPMORGAN CHASE & CO | 1,490,508 | $64,085,673 | ▲ +25,494 | 0.00% | 2026-06-30 |
| JENNISON ASSOCIATES LLC | 1,172,133 | $51,562,131 | ▼ -279,087 | 0.03% | 2026-06-30 |
| CITADEL ADVISORS LLC | 1,156,036 | $50,854,023 | ▼ -10,895 | 0.01% | 2026-06-30 |
| VANGUARD CAPITAL MANAGEMENT LLC | 1,132,001 | $49,796,724 | New position | 0.00% | 2026-06-30 |
| STATE STREET CORP | 1,021,534 | $44,937,281 | ▲ +265,307 | 0.00% | 2026-06-30 |
| PERCEPTIVE ADVISORS LLC | 905,000 | $39,810,950 | ▲ +246,561 | 0.60% | 2026-06-30 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 680,916 | $29,953,495 | ▼ -289,674 | 0.31% | 2026-06-30 |
| Siren, L.L.C. | 610,515 | $26,856,555 | ▲ +310,515 | 0.54% | 2026-06-30 |
| EVENTIDE ASSET MANAGEMENT, LLC | 474,981 | $20,894,402 | ▼ -170,549 | 0.28% | 2026-06-30 |
| GEODE CAPITAL MANAGEMENT, LLC | 457,145 | $20,113,984 | ▲ +67,273 | 0.00% | 2026-06-30 |
| BAKER BROS. ADVISORS LP | 400,000 | $17,596,000 | Unchanged | 0.09% | 2026-06-30 |
| Casdin Capital, LLC | 400,000 | $17,596,000 | New position | 0.88% | 2026-06-30 |
| GOLDMAN SACHS GROUP INC | 388,810 | $17,103,752 | ▲ +125,636 | 0.00% | 2026-06-30 |
| Driehaus Capital Management LLC | 385,447 | $16,955,814 | ▲ +308,814 | 0.10% | 2026-06-30 |
| MILLENNIUM MANAGEMENT LLC | 325,333 | $14,311,399 | ▲ +184,692 | 0.01% | 2026-06-30 |
| FRANKLIN RESOURCES INC | 290,113 | $12,762,071 | ▲ +114,630 | 0.00% | 2026-06-30 |
| Aberdeen Group plc | 284,138 | $12,499,231 | ▼ -280,037 | 0.02% | 2026-06-30 |
| FMR LLC | 278,292 | $12,242,065 | ▲ +196,897 | 0.00% | 2026-06-30 |
| Candriam S.C.A. | 233,208 | $10,248,950 | ▼ -3,605 | 0.05% | 2026-06-30 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 222,949 | $9,807,527 | New position | 0.00% | 2026-06-30 |
| Kalehua Capital Management LLC | 197,072 | $8,669,197 | Unchanged | 4.98% | 2026-06-30 |
| Longaeva Partners L.P. | 196,352 | $8,637,524 | ▲ +183,659 | 0.19% | 2026-06-30 |
| Artisan Partners Limited Partnership | 189,498 | $8,336,017 | New position | 0.01% | 2026-06-30 |
| Ensign Peak Advisors, Inc | 184,532 | $8,117,563 | ▼ -71,104 | 0.01% | 2026-06-30 |
| Soleus Capital Management, L.P. | 177,687 | $7,816,451 | ▼ -115,813 | 0.27% | 2026-06-30 |
| NORTHERN TRUST CORP | 154,476 | $6,795,399 | ▲ +37,700 | 0.00% | 2026-06-30 |
| MORGAN STANLEY | 151,047 | $6,644,558 | ▲ +18,024 | 0.00% | 2026-06-30 |
| Sofinnova Investments, Inc. | 144,432 | $6,353,564 | New position | 0.33% | 2026-06-30 |
| Qube Research & Technologies Ltd | 140,309 | $6,172,193 | ▲ +98,067 | 0.01% | 2026-06-30 |
| Alyeska Investment Group, L.P. | 136,222 | $5,992,406 | Unchanged | 0.02% | 2026-06-30 |
| GordonMD Global Investments LP | 136,000 | $5,982,640 | Unchanged | 2.89% | 2026-06-30 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 129,753 | $5,707,834 | ▲ +9,500 | 0.00% | 2026-06-30 |
| Sio Capital Management, LLC | 127,808 | $5,622,274 | ▼ -166,532 | 0.93% | 2026-06-30 |
| VANGUARD FIDUCIARY TRUST CO | 121,442 | $5,342,234 | New position | 0.00% | 2026-06-30 |
| Artia Global Partners LP | 119,741 | $5,267,407 | Unchanged | 0.97% | 2026-06-30 |
| UBS Group AG | 116,206 | $5,111,902 | ▼ -31,435 | 0.00% | 2026-06-30 |
| First Turn Management, LLC | 110,493 | $4,860,587 | New position | 0.52% | 2026-06-30 |
| CITIGROUP INC | 110,163 | $4,846,070 | ▲ +92,105 | 0.00% | 2026-06-30 |
| Ikarian Capital, LLC | 107,500 | $4,728,925 | New position | 0.51% | 2026-06-30 |
| D. E. Shaw & Co., Inc. | 101,644 | $4,471,320 | New position | 0.00% | 2026-06-30 |
| Rock Springs Capital Management LP | 99,429 | $4,373,882 | Unchanged | 0.21% | 2026-06-30 |
| Walleye Capital LLC | 97,347 | $4,282,295 | ▲ +82,250 | 0.02% | 2026-06-30 |
| Rhenman & Partners Asset Management AB | 97,100 | $4,271,429 | ▲ +9,600 | 0.40% | 2026-06-30 |
| BANK OF AMERICA CORP /DE/ | 88,908 | $3,911,063 | ▲ +38,038 | 0.00% | 2026-06-30 |
| AMERIPRISE FINANCIAL INC | 82,232 | $3,617,386 | New position | 0.00% | 2026-06-30 |
| Integral Health Asset Management, LLC | 75,000 | $3,299,250 | ▲ +25,000 | 0.13% | 2026-06-30 |
| SUPERSTRING CAPITAL MANAGEMENT LP | 63,156 | $2,778,232 | ▼ -77,868 | 1.75% | 2026-06-30 |
| STEMPOINT CAPITAL LP | 59,426 | $2,614,150 | ▲ +22,886 | 0.45% | 2026-06-30 |
| DEUTSCHE BANK AG TAUNUSANLAGE 12 D-60325 | 53,353 | $2,346,998 | ▲ +40,104 | 0.00% | 2026-06-30 |
| SEVEN GRAND MANAGERS, LLC | 50,000 | $2,199,500 | Unchanged | 0.09% | 2026-06-30 |
| Point72 Asset Management, L.P. | 49,328 | $2,169,939 | ▼ -87,221 | 0.00% | 2026-06-30 |
| TD Asset Management Inc | 47,396 | $2,084,950 | ▼ -35,600 | 0.00% | 2026-06-30 |
| ALPS ADVISORS INC | 45,525 | $2,002,645 | ▲ +8,897 | 0.01% | 2026-06-30 |
| SILVERARC CAPITAL MANAGEMENT, LLC | 42,478 | $1,868,607 | ▲ +3,061 | 0.19% | 2026-06-30 |
| Russell Investments Group, Ltd. | 42,258 | $1,858,960 | ▼ -6,161 | 0.00% | 2026-06-30 |
| Bank of New York Mellon Corp | 41,586 | $1,829,361 | ▲ +7,808 | 0.00% | 2026-06-30 |
| Nuveen, LLC | 41,259 | $1,814,984 | ▲ +17,525 | 0.00% | 2026-06-30 |
| XTX Topco Ltd | 38,096 | $1,675,843 | ▲ +14,545 | 0.02% | 2026-06-30 |
| WELLINGTON MANAGEMENT GROUP LLP | 37,365 | $1,643,686 | ▼ -8,714 | 0.00% | 2026-06-30 |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | 35,968 | $1,582,232 | New position | 0.02% | 2026-06-30 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 35,420 | $1,558,126 | ▼ -29,038 | 0.00% | 2026-06-30 |
| BOOTHBAY FUND MANAGEMENT, LLC | 32,500 | $1,429,675 | New position | 0.02% | 2026-06-30 |
| BNP PARIBAS FINANCIAL MARKETS | 31,803 | $1,399,014 | ▼ -8,767 | 0.00% | 2026-06-30 |
| Ishara Investments LP | 123,000 | $1,350,540 | ▲ +73,800 | 0.99% | 2026-06-30 |
| Swiss National Bank | 27,000 | $1,187,730 | New position | 0.00% | 2026-06-30 |
| Quadrature Capital Ltd | 26,023 | $1,144,752 | New position | 0.01% | 2026-06-30 |
| Trexquant Investment LP | 23,810 | $1,047,402 | New position | 0.01% | 2026-06-30 |
| NEW YORK STATE COMMON RETIREMENT FUND | 23,586 | $1,037,548 | ▲ +18,286 | 0.00% | 2026-06-30 |
| ALLIANCEBERNSTEIN L.P. | 25,450 | $1,020,291 | ▲ +9,040 | 0.00% | 2026-06-30 |
| RHUMBLINE ADVISERS | 22,309 | $981,362 | ▲ +4,001 | 0.00% | 2026-06-30 |
| Maven Securities LTD | 20,000 | $879,800 | ▼ -5,000 | 0.02% | 2026-06-30 |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 18,645 | $820,193 | ▲ +14,529 | 0.00% | 2026-06-30 |
| Susquehanna Portfolio Strategies, LLC | 18,034 | $793,316 | New position | 0.01% | 2026-06-30 |
| Rafferty Asset Management, LLC | 18,004 | $791,996 | ▼ -4,133 | 0.00% | 2026-06-30 |
| Shay Capital LLC | 18,000 | $791,820 | New position | 0.05% | 2026-06-30 |
| WELLS FARGO & COMPANY/MN | 16,821 | $739,955 | ▲ +10,927 | 0.00% | 2026-06-30 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 15,800 | $695,042 | ▲ +8,490 | 0.00% | 2026-06-30 |
| Engineers Gate Manager LP | 15,603 | $686,376 | New position | 0.01% | 2026-06-30 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 14,852 | $653,339 | ▲ +13,984 | 0.00% | 2026-06-30 |
| KENNEDY CAPITAL MANAGEMENT LLC | 12,621 | $555,198 | ▲ +337 | 0.01% | 2026-06-30 |
| Invesco Ltd. | 12,418 | $546,267 | New position | 0.00% | 2026-06-30 |
| MetLife Investment Management, LLC | 10,972 | $482,658 | ▲ +2,407 | 0.00% | 2026-06-30 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 10,622 | $467,262 | ▲ +10,506 | 0.00% | 2026-06-30 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 10,582 | $463,369 | ▲ +1,397 | 0.00% | 2026-06-30 |
| Jump Financial, LLC | 10,473 | $460,708 | New position | 0.00% | 2026-06-30 |
| VANGUARD ASSET MANAGEMENT, Ltd | 9,535 | $419,445 | New position | 0.00% | 2026-06-30 |
| PROFUND ADVISORS LLC | 9,140 | $402,069 | ▼ -799 | 0.01% | 2026-06-30 |
| Virtus Investment Advisers, LLC | 9,109 | $400,705 | ▲ +2,735 | 0.09% | 2026-06-30 |
| Legal & General Group Plc | 9,044 | $397,846 | ▲ +7,612 | 0.00% | 2026-06-30 |
| Vanguard Global Advisers, LLC | 7,852 | $345,409 | New position | 0.00% | 2026-06-30 |
| China Universal Asset Management Co., Ltd. | 7,186 | $316,112 | ▼ -734 | 0.02% | 2026-06-30 |
| Quarry LP | 6,750 | $296,933 | ▲ +446 | 0.02% | 2026-06-30 |
| BARCLAYS PLC | 6,495 | $285,715 | ▼ -11,890 | 0.00% | 2026-06-30 |
| VARCOV Co. | 6,418 | $282,328 | ▼ -153 | 0.11% | 2026-06-30 |
| Jupiter Topco LLC | 6,400 | $281,024 | New position | 0.00% | 2026-06-30 |
| Police & Firemen's Retirement System of New Jersey | 5,438 | $239,218 | ▲ +1,206 | 0.00% | 2026-06-30 |
| Squarepoint Ops LLC | 5,415 | $238,206 | ▼ -9,802 | 0.00% | 2026-06-30 |
| INTECH INVESTMENT MANAGEMENT LLC | 5,218 | $229,540 | ▼ -271 | 0.00% | 2026-06-30 |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 5,215 | $229,408 | New position | 0.00% | 2026-06-30 |
| SEI INVESTMENTS CO | 5,158 | $226,900 | New position | 0.00% | 2026-06-30 |
| Verition Fund Management LLC | 5,000 | $219,950 | New position | 0.00% | 2026-06-30 |
| AlphaCentric Advisors LLC | 4,863 | $213,923 | ▲ +45 | 0.18% | 2026-06-30 |
| Jain Global LLC | 4,780 | $210,272 | New position | 0.00% | 2026-06-30 |
| AXQ CAPITAL, LP | 4,597 | $202,222 | New position | 0.02% | 2026-06-30 |
| STRS OHIO | 3,500 | $153,965 | ▲ +600 | 0.00% | 2026-06-30 |
| Vanguard Investments Australia, Ltd. | 3,490 | $153,525 | New position | 0.00% | 2026-06-30 |
| KLP KAPITALFORVALTNING AS | 3,100 | $136,369 | New position | 0.00% | 2026-06-30 |
| Mirae Asset Global Investments Co., Ltd. | 2,019 | $88,816 | ▼ -309 | 0.00% | 2026-06-30 |
| Quantbot Technologies LP | 1,820 | $80,062 | ▲ +1,642 | 0.00% | 2026-06-30 |
| Ameritas Investment Partners, Inc. | 1,673 | $73,595 | ▲ +371 | 0.00% | 2026-06-30 |
| Tower Research Capital LLC (TRC) | 1,279 | $56,263 | ▼ -1,073 | 0.00% | 2026-06-30 |
| Mitsubishi UFJ Asset Management Co., Ltd. | 1,000 | $43,990 | New position | 0.00% | 2026-06-30 |
| GF FUND MANAGEMENT CO. LTD. | 946 | $41,615 | ▼ -57 | 0.00% | 2026-06-30 |
| State of Wyoming | 804 | $35,368 | New position | 0.00% | 2026-06-30 |
| SIMPLEX TRADING, LLC | 800 | $35,192 | New position | 0.00% | 2026-06-30 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 709 | $31,189 | ▲ +338 | 0.00% | 2026-06-30 |
| ROYAL BANK OF CANADA | 568 | $25,000 | ▲ +538 | 0.00% | 2026-06-30 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 478,016 | $21,029 | ▼ -278,360 | 0.00% | 2026-06-30 |
| NISA INVESTMENT ADVISORS, LLC | 385 | $16,936 | New position | 0.00% | 2026-06-30 |
| GAMMA Investing LLC | 244 | $10,734 | ▲ +6 | 0.00% | 2026-06-30 |
| Federation des caisses Desjardins du Quebec | 210 | $9,238 | New position | 0.00% | 2026-06-30 |
| Farther Finance Advisors, LLC | 196 | $8,622 | Unchanged | 0.00% | 2026-06-30 |
| Rockefeller Capital Management L.P. | 114 | $5,015 | ▼ -127 | 0.00% | 2026-06-30 |
| Hurley Capital, LLC | 113 | $4,971 | New position | 0.00% | 2026-06-30 |
| US BANCORP DE U.S. BANCORP | 104 | $4,575 | ▲ +53 | 0.00% | 2026-06-30 |
| Sterling Capital Management LLC | 65 | $2,859 | ▼ -40 | 0.00% | 2026-06-30 |
| Arax Advisory Partners | 41 | $1,804 | New position | 0.00% | 2026-06-30 |
| Bare Financial Services, Inc | 37 | $1,628 | New position | 0.00% | 2026-06-30 |
| Caitong International Asset Management Co., Ltd | 31 | $1,364 | ▼ -5 | 0.00% | 2026-06-30 |
| Hughes Financial Services, LLC | 25 | $1,100 | ▼ -1 | 0.00% | 2026-06-30 |
| EverSource Wealth Advisors, LLC | 20 | $880 | ▼ -3 | 0.00% | 2026-06-30 |
| Fortitude Family Office, LLC | 15 | $660 | Unchanged | 0.00% | 2026-06-30 |
| SJS Investment Consulting Inc. | 9 | $396 | New position | 0.00% | 2026-06-30 |
| CONTRAVISORY INVESTMENT MANAGEMENT, INC. | 6 | $264 | New position | 0.00% | 2026-06-30 |
| Integrated Wealth Concepts LLC | 6 | $264 | New position | 0.00% | 2026-06-30 |
| PNC Financial Services Group, Inc. | 5 | $220 | ▼ -11 | 0.00% | 2026-06-30 |
| Steward Partners Investment Advisory, LLC | 4 | $176 | ▼ -250 | 0.00% | 2026-06-30 |
| NATIONAL BANK OF CANADA /FI/ | 2 | $88 | New position | 0.00% | 2026-06-30 |
| ROTHSCHILD INVESTMENT LLC | 1 | $44 | Unchanged | 0.00% | 2026-06-30 |
| Allworth Financial LP | 1 | $44 | ▼ -28 | 0.00% | 2026-06-30 |
| Pacer Advisors, Inc. | 301 | $13 | New position | 0.00% | 2026-06-30 |
| Covestor Ltd | 12 | $1 | ▲ +9 | 0.00% | 2026-06-30 |
| POLEN CAPITAL MANAGEMENT LLC | 0 | $0 | Sold out | 2026-06-30 | |
| Hudson Bay Capital Management LP | 0 | $0 | Sold out | 2026-06-30 | |
| TWO SIGMA INVESTMENTS, LP | 0 | $0 | Sold out | 2026-06-30 | |
| SIGNATUREFD, LLC | 0 | $0 | Sold out | 2026-06-30 | |
| Root Financial Partners, LLC | 0 | $0 | Sold out | 2026-06-30 | |
| MAI Capital Management | 0 | $0 | Sold out | 2026-06-30 |