DEERFIELD MANAGEMENT COMPANY, L.P.
CIK 0001009258
Annualised vol
7.299496%
Beta
0.150783
HHI
664.815368
Top-10 weight
53.168022%
VaR 95%
0.65634%
VaR 99%
1.357289%
Max drawdown
19.384518%
Matched value
49.04329%
Returns of reported holdings
Loading returns…
Position changes vs prior quarter
What the latest 13F shows bought and sold against the quarter before, by share count.
| Ticker | Change | Shares now | Shares before | Share change % | Value now ($) |
|---|---|---|---|---|---|
| RVMD | ADDED | 202,392,000 | 2,297,000 | 8711.14% | 699,654,760 |
| VTRS | UNCHANGED | 20,206,170 | 20,206,170 | 0.0% | 320,873,980 |
| CELC | ADDED | 101,451,014 | 1,714,000 | 5818.96% | 265,584,985 |
| IONS | UNCHANGED | 61,979,669 | 61,979,669 | 0.0% | 250,072,355 |
| LEGN | ADDED | 8,137,638 | 7,687,638 | 5.85% | 235,014,985 |
| COGT | REDUCED | 5,006,104 | 9,043,903 | -44.65% | 193,736,225 |
| GMAB | ADDED | 6,865,000 | 2,462,000 | 178.84% | 188,581,550 |
| VERA | ADDED | 3,916,400 | 3,722,100 | 5.22% | 168,052,724 |
| BCRX | ADDED | 15,096,403 | 15,038,000 | 0.39% | 150,964,030 |
| TNGX | ADDED | 4,190,611 | 4,146,813 | 1.06% | 130,998,500 |
| AHCO | UNCHANGED | 11,477,730 | 11,477,730 | 0.0% | 119,597,947 |
| PHVS | ADDED | 3,376,042 | 3,126,042 | 8.0% | 116,743,532 |
| LRMR | UNCHANGED | 35,606,974 | 35,606,974 | 0.0% | 108,601,271 |
| MLYS | NEW | 3,958,000 | - | - | 106,786,840 |
| ALHC | UNCHANGED | 61,000,000 | 61,000,000 | 0.0% | 103,829,930 |
| IDYA | ADDED | 2,714,503 | 1,530,008 | 77.42% | 101,169,527 |
| XENE | UNCHANGED | 1,615,696 | 1,615,696 | 0.0% | 97,523,411 |
| SVRA | UNCHANGED | 13,569,000 | 13,569,000 | 0.0% | 83,585,040 |
| SNDX | UNCHANGED | 3,779,900 | 3,779,900 | 0.0% | 82,628,614 |
| ZBIO | ADDED | 67,200,000 | 65,000,000 | 3.38% | 80,316,096 |
| BMRN | ADDED | 1,332,836 | 851,556 | 56.52% | 76,264,876 |
| PFE | UNCHANGED | 3,040,000 | 3,040,000 | 0.0% | 73,203,200 |
| INDV | REDUCED | 1,648,895 | 3,097,790 | -46.77% | 67,654,162 |
| SPRY | UNCHANGED | 7,503,812 | 7,503,812 | 0.0% | 60,105,534 |
| STOK | UNCHANGED | 1,823,500 | 1,823,500 | 0.0% | 59,664,920 |
| GPCR | ADDED | 1,086,000 | 767,993 | 41.41% | 58,285,620 |
| NVST | UNCHANGED | 2,210,100 | 2,210,100 | 0.0% | 58,236,135 |
| CDNA | REDUCED | 1,997,618 | 2,191,000 | -8.83% | 56,932,113 |
| BSX | NEW | 1,315,000 | - | - | 56,124,200 |
| BLTE | ADDED | 357,199 | 304,013 | 17.49% | 55,003,288 |
| PBLS | NEW | 1,880,704 | - | - | 51,474,868 |
| CERT | REDUCED | 7,512,928 | 7,808,605 | -3.79% | 49,209,678 |
| IRON | UNCHANGED | 657,000 | 657,000 | 0.0% | 48,052,980 |
| LIVN | UNCHANGED | 34,280,000 | 34,280,000 | 0.0% | 46,485,120 |
| TYRA | ADDED | 1,017,000 | 549,000 | 85.25% | 32,482,980 |
| MNPR | UNCHANGED | 323,745 | 323,745 | 0.0% | 29,975,550 |
| SION | REDUCED | 680,916 | 970,590 | -29.85% | 29,953,495 |
| FHTX | UNCHANGED | 4,394,367 | 4,394,367 | 0.0% | 21,444,511 |
| BBNX | UNCHANGED | 1,324,000 | 1,324,000 | 0.0% | 20,747,080 |
| ALNY | UNCHANGED | 67,935 | 67,935 | 0.0% | 20,450,473 |
| DRUG | UNCHANGED | 283,000 | 283,000 | 0.0% | 19,866,600 |
| ODTX | NEW | 1,046,139 | - | - | 19,573,261 |
| KYTX | UNCHANGED | 2,000,000 | 2,000,000 | 0.0% | 17,820,000 |
| ALMR | NEW | 600,000 | - | - | 16,254,000 |
| CHE | NEW | 30,000 | - | - | 13,972,200 |
| SGP | UNCHANGED | 550,000 | 550,000 | 0.0% | 12,243,000 |
| NEO | REDUCED | 13,040,000 | 72,689,000 | -82.06% | 12,202,076 |
| ADAG | NEW | 2,666,666 | - | - | 11,199,997 |
| EMBC | UNCHANGED | 2,534,961 | 2,534,961 | 0.0% | 8,263,973 |
| VCYT | REDUCED | 101,000 | 726,000 | -86.09% | 5,931,730 |
| ANNX | UNCHANGED | 583,913 | 583,913 | 0.0% | 3,334,143 |
| ALEC | UNCHANGED | 1,055,192 | 1,055,192 | 0.0% | 2,120,936 |
| EW | UNCHANGED | 13,702 | 13,702 | 0.0% | 1,239,483 |
| MIRM | REDUCED | 6,027 | 70,000,000 | -99.99% | 705,581 |
| HUM | UNCHANGED | 917 | 917 | 0.0% | 364,251 |
| PMVP | UNCHANGED | 8,790 | 8,790 | 0.0% | 11,779 |
| CMPX | CLOSED OUT | 0 | 3,606,000 | -100.0% | 0 |
| TSHA | CLOSED OUT | 0 | 2,722,165 | -100.0% | 0 |
| NBIX | CLOSED OUT | 0 | 610,000 | -100.0% | 0 |
| KYMR | CLOSED OUT | 0 | 561,170 | -100.0% | 0 |
| CGEM | CLOSED OUT | 0 | 386,169 | -100.0% | 0 |
| QSI | CLOSED OUT | 0 | 333,333 | -100.0% | 0 |
| MANE | CLOSED OUT | 0 | 5,000 | -100.0% | 0 |
| MYGN | CLOSED OUT | 0 | 505 | -100.0% | 0 |
Holdings (latest quarter)
| Ticker | Change | Issuer | Class | CUSIP | Value ($) | Weight % | Shares |
|---|---|---|---|---|---|---|---|
| - | NUVALENT INC | COM | 670703107 | 2,130,183,575 | 22.22 | 1.724845E7 | |
| - | BROOKDALE SR LIVING INC | NOTE 3.500%10/1 | 112463AF1 | 585,704,753 | 6.11 | 3.06885E8 | |
| RVMD | ADDED | REVOLUTION MEDICINES INC | COM | 76155X100 | 447,973,760 | 4.67 | 2392000.0 |
| - | PRAXIS PRECISION MEDICINES I | COM NEW | 74006W207 | 322,520,281 | 3.36 | 963351.0 | |
| VTRS | UNCHANGED | VIATRIS INC | COM | 92556V106 | 320,873,980 | 3.35 | 2.020617E7 |
| - | CENTENE CORP DEL | COM | 15135B101 | 314,595,190 | 3.28 | 4901000.0 | |
| RVMD | ADDED | REVOLUTION MEDICINES INC | NOTE 0.500% 5/0 | 76155XAA8 | 251,681,000 | 2.63 | 2.0E8 |
| - | UNITED THERAPEUTICS CORP DEL | COM | 91307C102 | 247,616,310 | 2.58 | 457000.0 | |
| - | ARROWHEAD PHARMACEUTICALS IN | NOTE 1/1 | 04280AAC4 | 240,537,600 | 2.51 | 2.0E8 | |
| LEGN | ADDED | LEGEND BIOTECH CORP | SPONSORED ADS | 52490G102 | 235,014,985 | 2.45 | 8137638.0 |
| COGT | REDUCED | COGENT BIOSCIENCES INC | COM | 19240Q201 | 193,736,225 | 2.02 | 5006104.0 |
| GMAB | ADDED | GENMAB A/S | SPONSORED ADS | 372303206 | 188,581,550 | 1.97 | 6865000.0 |
| - | BROOKDALE SR LIVING INC | COM | 112463104 | 187,239,845 | 1.95 | 1.1637032E7 | |
| VERA | ADDED | VERA THERAPEUTICS INC | CL A | 92337R101 | 168,052,724 | 1.75 | 3916400.0 |
| IONS | UNCHANGED | IONIS PHARMACEUTICALS INC | COM | 462222100 | 156,967,955 | 1.64 | 1979669.0 |
| CELC | ADDED | CELCUITY INC | COM | 15102K100 | 151,805,085 | 1.58 | 1451014.0 |
| BCRX | ADDED | BIOCRYST PHARMACEUTICALS INC | COM | 09058V103 | 150,964,030 | 1.57 | 1.5096403E7 |
| - | NEWAMSTERDAM PHARMA COMPANY | ORDINARY SHARES | N62509109 | 144,533,699 | 1.51 | 4264789.0 | |
| - | ACADIA HEALTHCARE COMPANY IN | COM | 00404A109 | 133,475,600 | 1.39 | 4520000.0 | |
| TNGX | ADDED | TANGO THERAPEUTICS INC | COM | 87583X109 | 130,998,500 | 1.37 | 4190611.0 |
| AHCO | UNCHANGED | ADAPTHEALTH CORP | COMMON STOCK | 00653Q102 | 119,597,947 | 1.25 | 1.147773E7 |
| PHVS | ADDED | PHARVARIS N V | COM | N69605108 | 116,743,532 | 1.22 | 3376042.0 |
| CELC | ADDED | CELCUITY INC | NOTE 0.250% 8/0 | 15102KAB6 | 113,779,900 | 1.19 | 1.0E8 |
| - | ARROWHEAD PHARMACEUTICALS IN | COM | 04280A100 | 113,221,873 | 1.18 | 1389055.0 | |
| - | DIANTHUS THERAPEUTICS INC | COM | 252828108 | 109,695,511 | 1.14 | 1125313.0 | |
| LRMR | UNCHANGED | LARIMAR THERAPEUTICS INC | COM | 517125100 | 108,601,271 | 1.13 | 3.5606974E7 |
| MLYS | NEW | MINERALYS THERAPEUTICS INC | COM | 603170101 | 106,786,840 | 1.11 | 3958000.0 |
| ALHC | UNCHANGED | ALIGNMENT HEALTHCARE INC | NOTE 4.250%11/1 | 01625VAB0 | 103,829,930 | 1.08 | 6.1E7 |
| IDYA | ADDED | IDEAYA BIOSCIENCES INC | COM | 45166A102 | 101,169,527 | 1.06 | 2714503.0 |
| XENE | UNCHANGED | XENON PHARMACEUTICALS INC | COM | 98420N105 | 97,523,411 | 1.02 | 1615696.0 |
| IONS | UNCHANGED | IONIS PHARMACEUTICALS INC | NOTE 1.750% 6/1 | 462222AF7 | 93,104,400 | 0.97 | 6.0E7 |
| SVRA | UNCHANGED | SAVARA INC | COM | 805111101 | 83,585,040 | 0.87 | 1.3569E7 |
| - | LANTHEUS HLDGS INC | COM | 516544103 | 83,537,709 | 0.87 | 752999.0 | |
| SNDX | UNCHANGED | SYNDAX PHARMACEUTICALS INC | COM | 87164F105 | 82,628,614 | 0.86 | 3779900.0 |
| ZBIO | ADDED | ZENAS BIOPHARMA INC | NOTE 2.500% 4/0 | 98937LAA3 | 80,316,096 | 0.84 | 6.72E7 |
| BMRN | ADDED | BIOMARIN PHARMACEUTICAL INC | COM | 09061G101 | 76,264,876 | 0.8 | 1332836.0 |
| PFE | UNCHANGED | PFIZER INC | COM | 717081103 | 73,203,200 | 0.76 | 3040000.0 |
| INDV | REDUCED | INDIVIOR PHARMACEUTICALS INC | COM | 45579U109 | 67,654,162 | 0.71 | 1648895.0 |
| - | BIO RAD LABS INC | CL A | 090572207 | 66,376,413 | 0.69 | 226070.0 | |
| SPRY | UNCHANGED | ARS PHARMACEUTICALS INC | COM | 82835W108 | 60,105,534 | 0.63 | 7503812.0 |
| STOK | UNCHANGED | STOKE THERAPEUTICS INC | COM | 86150R107 | 59,664,920 | 0.62 | 1823500.0 |
| GPCR | ADDED | STRUCTURE THERAPEUTICS INC | SPONSORED ADS | 86366E106 | 58,285,620 | 0.61 | 1086000.0 |
| NVST | UNCHANGED | ENVISTA HOLDINGS CORPORATION | COM | 29415F104 | 58,236,135 | 0.61 | 2210100.0 |
| - | INSPIRE MED SYS INC | COM | 457730109 | 57,853,014 | 0.6 | 1296862.0 | |
| CDNA | REDUCED | CAREDX INC | COM | 14167L103 | 56,932,113 | 0.59 | 1997618.0 |
| BSX | NEW | BOSTON SCIENTIFIC CORP | COM | 101137107 | 56,124,200 | 0.59 | 1315000.0 |
| BLTE | ADDED | BELITE BIO INC | SPONSORED ADS | 07782B104 | 55,003,288 | 0.57 | 357199.0 |
| PBLS | NEW | PARABILIS MEDICINES INC | COM | 698955101 | 51,474,868 | 0.54 | 1880704.0 |
| CERT | REDUCED | CERTARA INC | COM | 15687V109 | 49,209,678 | 0.51 | 7512928.0 |
| IRON | UNCHANGED | DISC MEDICINE INC | COM | 254604101 | 48,052,980 | 0.5 | 657000.0 |
| LIVN | UNCHANGED | LIVANOVA PLC | NOTE 2.500% 3/1 | 53802LAB8 | 46,485,120 | 0.48 | 3.428E7 |
| - | BRIDGEBIO ONCOLOGY THERAPEUT | COM NEW | 107924102 | 37,227,099 | 0.39 | 4885446.0 | |
| TYRA | ADDED | TYRA BIOSCIENCES INC | COM | 90240B106 | 32,482,980 | 0.34 | 1017000.0 |
| MNPR | UNCHANGED | MONOPAR THERAPEUTICS INC | COM NEW | 61023L207 | 29,975,550 | 0.31 | 323745.0 |
| SION | REDUCED | SIONNA THERAPEUTICS INC | COM | 829401108 | 29,953,495 | 0.31 | 680916.0 |
| - | IMMUNOCORE HLDGS PLC | NOTE 2.500% 2/0 | 45258DAB1 | 27,104,340 | 0.28 | 3.0E7 | |
| - | AVALYN PHARMACEUTICALS INC | COM SHS | 05348Y105 | 24,064,520 | 0.25 | 731000.0 | |
| FHTX | UNCHANGED | FOGHORN THERAPEUTICS INC | COM | 344174107 | 21,444,511 | 0.22 | 4394367.0 |
| BBNX | UNCHANGED | BETA BIONICS INC | COM | 08659B102 | 20,747,080 | 0.22 | 1324000.0 |
| ALNY | UNCHANGED | ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 20,450,473 | 0.21 | 67935.0 |
| DRUG | UNCHANGED | BRIGHT MINDS BIOSCIENCES INC | COM NEW | 10919W405 | 19,866,600 | 0.21 | 283000.0 |
| ODTX | NEW | ODYSSEY THERAPEUTICS INC | COMMON STOCK | 67613T104 | 19,573,261 | 0.2 | 1046139.0 |
| - | THE ONCOLOGY INSTITUTE INC | COM | 68236X100 | 18,245,082 | 0.19 | 3360052.0 | |
| KYTX | UNCHANGED | KYVERNA THERAPEUTICS INC | COM | 501976104 | 17,820,000 | 0.19 | 2000000.0 |
| ALMR | NEW | ALAMAR BIOSCIENCES INC | COMMON STOCK | 010911105 | 16,254,000 | 0.17 | 600000.0 |
| CHE | NEW | CHEMED CORP NEW | COM | 16359R103 | 13,972,200 | 0.15 | 30000.0 |
| SGP | UNCHANGED | SPYGLASS PHARMA INC | COM SHS | 85220G109 | 12,243,000 | 0.13 | 550000.0 |
| NEO | REDUCED | NEOGENOMICS INC | NOTE 0.250% 1/1 | 64049MAB6 | 12,202,076 | 0.13 | 1.304E7 |
| ADAG | NEW | ADAGENE INC | ADS | 005329107 | 11,199,997 | 0.12 | 2666666.0 |
| - | HEMAB THERAPEUTICS HLDGS INC | COM SHS | 423494103 | 10,100,750 | 0.11 | 275000.0 | |
| - | MOBIA MED INC | COMMON STOCK | 60705V103 | 8,988,077 | 0.09 | 670752.0 | |
| EMBC | UNCHANGED | EMBECTA CORP | COMMON STOCK | 29082K105 | 8,263,973 | 0.09 | 2534961.0 |
| VCYT | REDUCED | VERACYTE INC | COM | 92337F107 | 5,931,730 | 0.06 | 101000.0 |
| ANNX | UNCHANGED | ANNEXON INC | COM | 03589W102 | 3,334,143 | 0.03 | 583913.0 |
| ALEC | UNCHANGED | ALECTOR INC | COM | 014442107 | 2,120,936 | 0.02 | 1055192.0 |
| - | NEWAMSTERDAM PHARMA COMPANY | *W EXP 99/99/999 | N62509117 | 1,982,858 | 0.02 | 92787.0 | |
| EW | UNCHANGED | EDWARDS LIFESCIENCES CORP | COM | 28176E108 | 1,239,483 | 0.01 | 13702.0 |
| MIRM | REDUCED | MIRUM PHARMACEUTICALS INC | COM | 604749101 | 705,581 | 0.01 | 6027.0 |
| HUM | UNCHANGED | HUMANA INC | COM | 444859102 | 364,251 | 0.0 | 917.0 |
| - | THE ONCOLOGY INSTITUTE INC | *W EXP 99/99/999 | 68236X118 | 51,000 | 0.0 | 1250000.0 | |
| PMVP | UNCHANGED | PMV PHARMACEUTICALS INC | COM | 69353Y103 | 11,779 | 0.0 | 8790.0 |
| - | SURROZEN INC | *W EXP 08/01/203 | 86889P117 | 2,750 | 0.0 | 166666.0 |
Quarterly portfolios
| Period | Filed | Value ($) | Positions | Vol % | Beta | Max DD % |
|---|---|---|---|---|---|---|
| 2026-06-30 | 2026-08-14 | 9,586,027,944 | 82 | 7.299496 | 0.150783 | 19.384518 |
| 2026-03-31 | 2026-05-15 | 8,476,379,716 | 82 | 6.188943 | 0.121046 | 18.678957 |
| 2025-12-31 | 2026-02-17 | 7,830,165,970 | 150 | 6.344921 | 0.132562 | 18.393988 |
| 2025-09-30 | 2025-11-14 | 6,550,740,151 | 152 | 6.041922 | 0.15742 | 15.657258 |
| 2025-03-31 | 2025-05-15 | 5,064,779,427 | 123 | 5.56056 | 0.140639 | 13.0025 |
| 2024-12-31 | 2025-02-14 | 5,280,006,191 | 106 | 5.236772 | 0.118603 | 14.929165 |