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Institutional Holdings

BLTE

Ownership Summary

Institutions Holding
105
Total Shares Held
9,758,532
Total Value Held
$1,514,218,684
Quarter
2025-12-31

Active Positions

Increased Positions
10
1,374,978 shares
Decreased Positions
8
271,854 shares
Held Positions
4
112,819 shares
New Positions
78
7,998,881 shares
Sold Out Positions
5
60,541 shares
Institution Shares Value Change % of Portfolio Reported
Darwin Global Management, Ltd. 3,027,704 $486,915,357 New position 2025-12-31
Paradigm Biocapital Advisors LP 1,232,877 $189,844,565 ▲ +118,093 3.55% 2026-06-30
RTW INVESTMENTS, LP 715,332 $114,424,507 New position 2025-12-31
MILLENNIUM MANAGEMENT LLC 558,882 $89,398,765 New position 2025-12-31
MAVERICK CAPITAL LTD 396,311 $61,025,949 New position 0.54% 2026-06-30
EVENTIDE ASSET MANAGEMENT, LLC 383,091 $61,279,236 New position 2025-12-31
DEERFIELD MANAGEMENT COMPANY, L.P. 233,813 $37,400,727 New position 2025-12-31
Holocene Advisors, LP 84,067 $13,447,357 New position 2025-12-31
Logos Global Management LP 250,000 $38,496,250 New position 1.66% 2026-06-30
MORGAN STANLEY 28,013 $4,480,960 New position 2025-12-31
UBS Group AG 128,752 $20,595,170 New position 2025-12-31
CITADEL ADVISORS LLC 5,055 $808,598 New position 2025-12-31
GOLDMAN SACHS GROUP INC 44,599 $7,134,056 New position 2025-12-31
Affinity Asset Advisors, LLC 20,000 $3,199,200 New position 2025-12-31
MPM BioImpact LLC 87,760 $14,038,090 New position 2025-12-31
BANK OF AMERICA CORP /DE/ 1,852 $296,246 ▲ +681 2025-12-31
Patient Square Capital LP 110,000 $16,938,350 ▼ -6,684 2.62% 2026-06-30
JANE STREET GROUP, LLC 32,318 $5,169,587 New position 2025-12-31
BNP PARIBAS FINANCIAL MARKETS 2,448 $391,582 New position 2025-12-31
RENAISSANCE TECHNOLOGIES LLC 55,763 $8,586,666 ▲ +3,763 0.01% 2026-06-30
Point72 Asset Management, L.P. 284,437 $45,498,543 New position 2025-12-31
Soleus Capital Management, L.P. 40,354 $6,455,026 New position 2025-12-31
Trexquant Investment LP 49,516 $7,624,721 ▲ +34,444 0.04% 2026-06-30
TWO SIGMA INVESTMENTS, LP 38,100 $5,866,829 New position 0.00% 2026-06-30
PFM Health Sciences, LP 19,823 $3,170,887 New position 2025-12-31
JPMORGAN CHASE & CO 3 $480 New position 2025-12-31
Walleye Capital LLC 31,721 $4,884,558 New position 0.02% 2026-06-30
Artia Global Partners LP 17,989 $2,877,520 New position 2025-12-31
GEODE CAPITAL MANAGEMENT, LLC 10,445 $1,670,782 New position 2025-12-31
BALANCE CAPITAL PARTNERS L.P. 22,500 $3,464,663 ▲ +8,000 2.49% 2026-06-30
NATIONAL BANK OF CANADA /FI/ 20,000 $3,079,700 New position 0.00% 2026-06-30
STATE STREET CORP 15,740 $2,517,770 New position 2025-12-31
Verdad Advisers, LP 13,758 $2,118,526 ▼ -55 2.03% 2026-06-30
ORBIMED ADVISORS LLC 13,300 $2,048,001 New position 0.04% 2026-06-30
TD Asset Management Inc 13,010 $2,003,345 ▼ -20,400 0.00% 2026-06-30
BOOTHBAY FUND MANAGEMENT, LLC 11,897 $1,903,044 New position 2025-12-31
Qube Research & Technologies Ltd 12,171 $1,874,151 New position 0.00% 2026-06-30
Lighthouse Investment Partners, LLC 10,000 $1,539,850 New position 0.04% 2026-06-30
MANUFACTURERS LIFE INSURANCE COMPANY, THE 9,820 $1,512,133 ▼ -9,780 0.00% 2026-06-30
HighVista Strategies LLC 9,554 $1,471,173 ▲ +1,521 0.34% 2026-06-30
Squarepoint Ops LLC 8,785 $1,352,758 ▼ -8,196 0.00% 2026-06-30
BARCLAYS PLC 4,176 $667,993 New position 2025-12-31
Capricorn Fund Managers Ltd 6,400 $985,504 New position 0.08% 2026-06-30
Voleon Capital Management LP 6,289 $968,412 ▼ -1,594 0.02% 2026-06-30
SmartHarvest Portfolios, LLC 4,184 $669,273 New position 2025-12-31
XTX Topco Ltd 4,333 $667,217 ▼ -10,725 0.01% 2026-06-30
Mariner, LLC 3,835 $590,533 New position 0.00% 2026-06-30
Entropy Technologies, LP 3,700 $569,745 New position 0.02% 2026-06-30
High Net Worth Advisory Group LLC 3,500 $538,948 Unchanged 0.11% 2026-06-30
FMR LLC 3,100 $477,354 New position 0.00% 2026-06-30
AMERIPRISE FINANCIAL INC 13,221 $2,114,832 New position 2025-12-31
Engineers Gate Manager LP 2,773 $427,000 ▲ +284 0.01% 2026-06-30
Virtus Investment Advisers, LLC 1,882 $301,045 New position 2025-12-31
FRED ALGER MANAGEMENT, LLC 79,394 $12,699,864 New position 2025-12-31
Jain Global LLC 2,101 $323,522 New position 0.00% 2026-06-30
Arrowpoint Investment Partners (Singapore) Pte. Ltd. 3,049 $487,718 New position 2025-12-31
DYMON ASIA CAPITAL (SINGAPORE) PTE. LTD. 1,900 $292,572 Unchanged 0.01% 2026-06-30
R Squared Ltd 1,338 $206,032 New position 0.11% 2026-06-30
Independent Advisor Alliance 1,319 $203,106 Unchanged 0.00% 2026-06-30
Mirae Asset Global Investments Co., Ltd. 1,290 $206,348 New position 2025-12-31
ROYAL BANK OF CANADA 2,092 $334,000 New position 2025-12-31
Bayforest Capital Ltd 307 $47,273 New position 0.04% 2026-06-30
WELLS FARGO & COMPANY/MN 100 $15,996 New position 2025-12-31
E Fund Management (Hong Kong) Co., Ltd. 113 $17,400 ▲ +30 0.01% 2026-06-30
Duquesne Family Office LLC 106,100 $16,338 Unchanged 0.31% 2026-06-30
PRICE T ROWE ASSOCIATES INC /MD/ 105,859 $16,301 ▼ -175,946 0.00% 2026-06-30
CITIGROUP INC 2,137 $341,835 New position 2025-12-31
Integrated Wealth Concepts LLC 47 $7,237 New position 0.00% 2026-06-30
JONES FINANCIAL COMPANIES LLLP 6 $960 New position 2025-12-31
SBI Securities Co., Ltd. 50 $7,998 New position 2025-12-31
Rossby Financial, LCC 13 $2,079 New position 2025-12-31
NISA INVESTMENT ADVISORS, LLC 17 $2,618 ▲ +4 0.00% 2026-06-30
Bell Investment Advisors, Inc 13 $2,002 ▲ +9 0.00% 2026-06-30
GSA CAPITAL PARTNERS LLP 1,463 $234 New position 2025-12-31
FIDUCIARY FINANCIAL ADVISORS 3 $462 New position 0.00% 2026-06-30
Arax Advisory Partners 2 $308 New position 0.00% 2026-06-30
PERCEPTIVE ADVISORS LLC 414,239 $66,261,670 New position 2025-12-31
Longaeva Partners L.P. 0 $0 Sold out 2026-06-30
ADAR1 Capital Management, LLC 79,678 $12,745,292 New position 2025-12-31
Quadrature Capital Ltd 24,832 $3,972,127 New position 2025-12-31
Aquatic Capital Management LLC 0 $0 Sold out 2026-06-30
BANK OF MONTREAL /CAN/ 15,538 $2,498,821 New position 2025-12-31
HRT FINANCIAL LP 8,164 $1,305 New position 2025-12-31
Convergence Financial, LLC 0 $0 Sold out 2026-06-30
AXQ CAPITAL, LP 0 $0 Sold out 2026-06-30
Merit Financial Group, LLC 0 $0 Sold out 2026-06-30
Caitong International Asset Management Co., Ltd 283 $45,269 New position 2025-12-31
TD Waterhouse Canada Inc. 70 $11,197 New position 2025-12-31
RA CAPITAL MANAGEMENT, L.P. 432,484 $69,180,141 New position 2025-12-31
MARSHALL WACE, LLP 192,700 $30,824,292 New position 2025-12-31
Western Standard LLC 60,026 $9,601,759 New position 2025-12-31
Squadron Capital Management LLC 26,000 $4,158,960 New position 2025-12-31
SUPERSTRING CAPITAL MANAGEMENT LP 24,703 $3,951,492 New position 2025-12-31
Woodline Partners LP 18,041 $2,885,838 New position 2025-12-31
Exome Asset Management LLC 14,328 $2,291,907 New position 2025-12-31
STEMPOINT CAPITAL LP 9,163 $1,465,713 New position 2025-12-31
WELLINGTON MANAGEMENT GROUP LLP 6,198 $991,432 New position 2025-12-31
PSP Research LLC 3,443 $550,742 New position 2025-12-31
Y-Intercept (Hong Kong) Ltd 3,152 $504,194 New position 2025-12-31
PRELUDE CAPITAL MANAGEMENT, LLC 3,119 $498,915 New position 2025-12-31
Brooklyn Investment Group 1,739 $287,440 New position 2025-12-31
EverSource Wealth Advisors, LLC 1,598 $255,616 New position 2025-12-31
Persistent Asset Partners Ltd 673 $107,653 New position 2025-12-31
China Universal Asset Management Co., Ltd. 500 $79,980 New position 2025-12-31
OSAIC HOLDINGS, INC. 195 $31,192 New position 2025-12-31