Siren, L.L.C.
CIK 0002005245
Annualised vol
13.825837%
Beta
0.215281
HHI
316.530463
Top-10 weight
44.631006%
VaR 95%
1.221163%
VaR 99%
2.813141%
Max drawdown
34.074801%
Matched value
95.766899%
Returns of reported holdings
Loading returns…
Position changes vs prior quarter
What the latest 13F shows bought and sold against the quarter before, by share count.
| Ticker | Change | Shares now | Shares before | Share change % | Value now ($) |
|---|---|---|---|---|---|
| SRRK | REDUCED | 9,575,013 | 10,825,013 | -11.55% | 526,625,715 |
| KYMR | REDUCED | 2,935,830 | 3,186,830 | -7.88% | 336,651,626 |
| ERAS | ADDED | 11,397,781 | 11,244,246 | 1.37% | 208,807,348 |
| MANE | ADDED | 1,655,374 | 1,505,374 | 9.96% | 203,511,680 |
| TNGX | ADDED | 6,179,364 | 5,657,105 | 9.23% | 193,166,919 |
| RVMD | REDUCED | 900,000 | 1,110,980 | -18.99% | 168,552,000 |
| BCAX | REDUCED | 5,602,970 | 5,802,970 | -3.45% | 166,352,179 |
| ARWR | ADDED | 1,715,476 | 1,615,476 | 6.19% | 139,828,449 |
| ONC | UNCHANGED | 465,000 | 465,000 | 0.0% | 132,511,050 |
| EWTX | REDUCED | 3,184,629 | 4,430,263 | -28.12% | 129,391,476 |
| RYTM | ADDED | 1,136,275 | 725,511 | 56.62% | 126,160,613 |
| LXRX | UNCHANGED | 44,303,518 | 44,303,518 | 0.0% | 106,328,443 |
| ELVN | ADDED | 1,774,411 | 746,226 | 137.78% | 90,051,358 |
| SYRE | ADDED | 968,598 | 818,598 | 18.32% | 85,992,130 |
| PBLS | NEW | 2,992,259 | - | - | 81,898,129 |
| XENE | UNCHANGED | 1,318,564 | 1,318,564 | 0.0% | 79,588,523 |
| SLDB | UNCHANGED | 7,690,405 | 7,690,405 | 0.0% | 76,827,146 |
| COAG | NEW | 2,086,834 | - | - | 76,649,413 |
| RCUS | REDUCED | 2,420,430 | 3,007,077 | -19.51% | 74,621,857 |
| COGT | ADDED | 1,859,279 | 1,709,279 | 8.78% | 71,954,097 |
| RLAY | NEW | 3,650,000 | - | - | 68,291,500 |
| TSHA | ADDED | 9,846,579 | 8,829,913 | 11.51% | 67,055,203 |
| DFTX | ADDED | 1,419,493 | 919,493 | 54.38% | 66,772,951 |
| STOK | UNCHANGED | 1,995,347 | 1,995,347 | 0.0% | 65,287,754 |
| IRON | REDUCED | 888,401 | 988,401 | -10.12% | 64,977,649 |
| CYTK | ADDED | 758,952 | 613,952 | 23.62% | 64,655,121 |
| SEPN | REDUCED | 1,900,000 | 2,000,000 | -5.0% | 63,631,000 |
| OLMA | ADDED | 4,856,949 | 4,756,949 | 2.1% | 60,760,432 |
| KLRA | NEW | 2,214,286 | - | - | 48,780,721 |
| DYN | REDUCED | 2,129,125 | 2,229,125 | -4.49% | 47,287,866 |
| GPCR | REDUCED | 872,967 | 1,328,698 | -34.3% | 46,852,139 |
| TBLA | REDUCED | 8,423,410 | 9,969,495 | -15.51% | 42,117,050 |
| PVLA | UNCHANGED | 257,485 | 257,485 | 0.0% | 39,348,858 |
| SLN | ADDED | 3,311,438 | 2,911,438 | 13.74% | 36,359,589 |
| DNLI | UNCHANGED | 1,396,513 | 1,396,513 | 0.0% | 35,918,314 |
| RELY | UNCHANGED | 1,543,271 | 1,543,271 | 0.0% | 34,584,703 |
| CGEM | ADDED | 1,893,410 | 1,193,410 | 58.66% | 34,478,996 |
| TRVI | UNCHANGED | 1,786,867 | 1,786,867 | 0.0% | 33,325,070 |
| ORIC | UNCHANGED | 2,998,192 | 2,998,192 | 0.0% | 32,470,419 |
| GOOGL | ADDED | 90,000 | 65,703 | 36.98% | 32,163,300 |
| ABSI | ADDED | 2,474,764 | 1,800,000 | 37.49% | 28,682,515 |
| SION | ADDED | 610,515 | 300,000 | 103.51% | 26,856,555 |
| RAPP | UNCHANGED | 641,469 | 641,469 | 0.0% | 26,730,013 |
| AMLX | ADDED | 1,480,586 | 1,230,000 | 20.37% | 26,591,325 |
| ANNX | ADDED | 4,458,646 | 3,958,646 | 12.63% | 25,458,869 |
| MNPR | UNCHANGED | 270,118 | 270,118 | 0.0% | 25,010,226 |
| ORKA | NEW | 250,000 | - | - | 23,792,500 |
| SPTX | NEW | 1,095,316 | - | - | 23,790,264 |
| DMRA | UNCHANGED | 900,000 | 900,000 | 0.0% | 23,409,000 |
| TYRA | NEW | 725,000 | - | - | 23,156,500 |
| MSFT | ADDED | 61,500 | 41,380 | 48.62% | 22,940,730 |
| ZURA | UNCHANGED | 3,734,866 | 3,734,866 | 0.0% | 22,035,709 |
| TSM | ADDED | 44,700 | 42,200 | 5.92% | 21,347,379 |
| NVDA | ADDED | 95,000 | 89,085 | 6.64% | 19,008,550 |
| RZLT | UNCHANGED | 3,328,287 | 3,328,287 | 0.0% | 17,307,092 |
| MPLT | UNCHANGED | 450,000 | 450,000 | 0.0% | 16,128,000 |
| NMRA | UNCHANGED | 8,497,822 | 8,497,822 | 0.0% | 14,446,297 |
| CTMX | UNCHANGED | 3,457,711 | 3,457,711 | 0.0% | 12,966,416 |
| GENB | UNCHANGED | 736,104 | 736,104 | 0.0% | 12,418,075 |
| IKT | UNCHANGED | 5,850,000 | 5,850,000 | 0.0% | 11,875,500 |
| ADAG | NEW | 2,666,666 | - | - | 11,199,997 |
| ENGN | NEW | 6,256,662 | - | - | 10,824,025 |
| WHWK | ADDED | 2,337,102 | 2,082,000 | 12.25% | 10,703,927 |
| DDOG | REDUCED | 40,000 | 54,300 | -26.34% | 10,414,400 |
| NOW | ADDED | 100,000 | 87,090 | 14.82% | 9,928,000 |
| AVGO | ADDED | 25,000 | 15,000 | 66.67% | 9,443,750 |
| IONQ | UNCHANGED | 170,000 | 170,000 | 0.0% | 9,054,200 |
| FROG | REDUCED | 95,500 | 128,816 | -25.86% | 8,679,040 |
| OCS | NEW | 625,000 | - | - | 8,668,750 |
| IREN | ADDED | 175,000 | 43,100 | 306.03% | 8,002,750 |
| AMZN | REDUCED | 32,500 | 46,641 | -30.32% | 7,746,050 |
| CRWD | REDUCED | 10,000 | 23,070 | -56.65% | 7,631,400 |
| DSGN | NEW | 523,212 | - | - | 7,570,878 |
| PDD | ADDED | 95,000 | 83,401 | 13.91% | 7,246,600 |
| MSLE | UNCHANGED | 892,074 | 892,074 | 0.0% | 6,935,875 |
| DT | ADDED | 155,000 | 150,000 | 3.33% | 6,806,050 |
| AAPL | NEW | 23,000 | - | - | 6,655,280 |
| TENX | UNCHANGED | 427,141 | 427,141 | 0.0% | 6,214,902 |
| VTVT | UNCHANGED | 163,000 | 163,000 | 0.0% | 6,136,950 |
| ELOX | NEW | 400,000 | - | - | 5,552,000 |
| AGMB | UNCHANGED | 411,250 | 411,250 | 0.0% | 5,338,025 |
| BABA | NEW | 50,000 | - | - | 4,799,000 |
| KRRO | UNCHANGED | 347,718 | 347,718 | 0.0% | 4,582,923 |
| CLBT | UNCHANGED | 311,544 | 311,544 | 0.0% | 4,548,542 |
| IVVD | ADDED | 5,000,000 | 4,000,000 | 25.0% | 4,362,000 |
| OUST | NEW | 67,500 | - | - | 4,220,100 |
| PALI | NEW | 2,000,000 | - | - | 4,180,000 |
| AEVA | ADDED | 145,459 | 110,000 | 32.24% | 4,177,582 |
| SEER | UNCHANGED | 2,458,673 | 2,458,673 | 0.0% | 4,081,397 |
| NBP | REDUCED | 2,004,739 | 3,000,000 | -33.18% | 3,909,241 |
| GTLB | ADDED | 125,000 | 100,000 | 25.0% | 3,816,250 |
| ODTX | NEW | 200,000 | - | - | 3,742,000 |
| FHTX | UNCHANGED | 720,720 | 720,720 | 0.0% | 3,517,114 |
| AGEN | UNCHANGED | 1,064,250 | 1,064,250 | 0.0% | 3,256,605 |
| MNDY | ADDED | 42,500 | 25,000 | 70.0% | 3,076,575 |
| ZTS | NEW | 35,000 | - | - | 2,515,100 |
| WK | REDUCED | 45,000 | 92,500 | -51.35% | 2,182,950 |
| NFLX | NEW | 25,000 | - | - | 1,784,925 |
| KLRS | UNCHANGED | 435,798 | 435,798 | 0.0% | 1,773,698 |
| QNT | NEW | 20,000 | - | - | 1,634,800 |
| RANI | UNCHANGED | 2,000,000 | 2,000,000 | 0.0% | 1,520,800 |
| TSLA | REDUCED | 3,500 | 21,500 | -83.72% | 1,472,100 |
| BEKE | UNCHANGED | 100,000 | 100,000 | 0.0% | 1,453,000 |
| ENTX | NEW | 736,457 | - | - | 1,303,529 |
| MDLN | UNCHANGED | 25,000 | 25,000 | 0.0% | 986,000 |
| LITE | NEW | 1,055 | - | - | 905,253 |
| FIG | UNCHANGED | 50,000 | 50,000 | 0.0% | 904,500 |
| GOSS | UNCHANGED | 5,208,968 | 5,208,968 | 0.0% | 857,396 |
| FOXA | NEW | 10,000 | - | - | 521,600 |
| T | NEW | 25,000 | - | - | 517,500 |
| NU | UNCHANGED | 25,000 | 25,000 | 0.0% | 334,000 |
| WVE | CLOSED OUT | 0 | 2,450,000 | -100.0% | 0 |
| FULC | CLOSED OUT | 0 | 2,350,000 | -100.0% | 0 |
| BCYC | CLOSED OUT | 0 | 1,560,882 | -100.0% | 0 |
| FPS | CLOSED OUT | 0 | 100,000 | -100.0% | 0 |
| AS | CLOSED OUT | 0 | 50,000 | -100.0% | 0 |
| PRMB | CLOSED OUT | 0 | 50,000 | -100.0% | 0 |
| MU | CLOSED OUT | 0 | 6,000 | -100.0% | 0 |
Holdings (latest quarter)
| Ticker | Change | Issuer | Class | CUSIP | Value ($) | Weight % | Shares |
|---|---|---|---|---|---|---|---|
| SRRK | REDUCED | Scholar Rock Holding Corp | COM | 80706P103 | 526,625,715 | 10.66 | 9575013.0 |
| KYMR | REDUCED | Kymera Therapeutics Inc | COM | 501575104 | 336,651,626 | 6.81 | 2935830.0 |
| ERAS | ADDED | Erasca Inc | COM | 29479A108 | 208,807,348 | 4.23 | 1.1397781E7 |
| MANE | ADDED | Veradermics Inc | COMMON STOCK | 922967104 | 203,511,680 | 4.12 | 1655374.0 |
| TNGX | ADDED | Tango Therapeutics Inc | COM | 87583X109 | 193,166,919 | 3.91 | 6179364.0 |
| RVMD | REDUCED | Revolution Medicines Inc | COM | 76155X100 | 168,552,000 | 3.41 | 900000.0 |
| BCAX | REDUCED | Bicara Therapeutics Inc | COM | 055477103 | 166,352,179 | 3.37 | 5602970.0 |
| ARWR | ADDED | Arrowhead Pharmaceuticals Inc | COM | 04280A100 | 139,828,449 | 2.83 | 1715476.0 |
| ONC | UNCHANGED | BeOne Medicines AG | SPONSORED ADS | 07725L102 | 132,511,050 | 2.68 | 465000.0 |
| EWTX | REDUCED | Edgewise Therapeutics Inc | COM | 28036F105 | 129,391,476 | 2.62 | 3184629.0 |
| RYTM | ADDED | Rhythm Pharmaceuticals Inc | COM | 76243J105 | 126,160,613 | 2.55 | 1136275.0 |
| LXRX | UNCHANGED | Lexicon Pharmaceuticals Inc | COM NEW | 528872302 | 106,328,443 | 2.15 | 4.4303518E7 |
| ELVN | ADDED | Enliven Therapeutics Inc | COM | 29337E102 | 90,051,358 | 1.82 | 1774411.0 |
| SYRE | ADDED | Spyre Therapeutics Inc | COM NEW | 00773J202 | 85,992,130 | 1.74 | 968598.0 |
| PBLS | NEW | Parabilis Medicines Inc | COM | 698955101 | 81,898,129 | 1.66 | 2992259.0 |
| XENE | UNCHANGED | Xenon Pharmaceuticals Inc | COM | 98420N105 | 79,588,523 | 1.61 | 1318564.0 |
| SLDB | UNCHANGED | Solid Biosciences Inc | COM NEW | 83422E204 | 76,827,146 | 1.55 | 7690405.0 |
| - | Abivax SA | SPONSORED ADS | 00370M103 | 76,757,760 | 1.55 | 576000.0 | |
| COAG | NEW | Hemab Therapeutics Holdings Inc | COM SHS | 423494103 | 76,649,413 | 1.55 | 2086834.0 |
| COGT | ADDED | Cogent Biosciences Inc | COM | 19240Q201 | 71,954,097 | 1.46 | 1859279.0 |
| RLAY | NEW | Relay Therapeutics Inc | COM | 75943R102 | 68,291,500 | 1.38 | 3650000.0 |
| TSHA | ADDED | Taysha Gene Therapies Inc | COM SHS | 877619106 | 67,055,203 | 1.36 | 9846579.0 |
| DFTX | ADDED | Definium Therapeutics Inc | COM SHS | 24477V105 | 66,772,951 | 1.35 | 1419493.0 |
| STOK | UNCHANGED | Stoke Therapeutics Inc | COM | 86150R107 | 65,287,754 | 1.32 | 1995347.0 |
| IRON | REDUCED | Disc Medicine Inc | COM | 254604101 | 64,977,649 | 1.31 | 888401.0 |
| CYTK | ADDED | Cytokinetics Inc | COM NEW | 23282W605 | 64,655,121 | 1.31 | 758952.0 |
| SEPN | REDUCED | Septerna Inc | COM | 81734D104 | 63,631,000 | 1.29 | 1900000.0 |
| OLMA | ADDED | Olema Pharmaceuticals Inc | COM | 68062P106 | 60,760,432 | 1.23 | 4856949.0 |
| RCUS | REDUCED | Arcus Biosciences Inc | COM | 03969F109 | 53,798,350 | 1.09 | 1745000.0 |
| - | Crinetics Pharmaceuticals Inc | COM | 22663K107 | 53,165,887 | 1.08 | 1420788.0 | |
| KLRA | NEW | Kailera Therapeutics Inc | COMMON STOCK | 482931102 | 48,780,721 | 0.99 | 2214286.0 |
| DYN | REDUCED | Dyne Therapeutics, Inc | COM | 26818M108 | 47,287,866 | 0.96 | 2129125.0 |
| GPCR | REDUCED | Structure Therapeutics Inc | SPONSORED ADS | 86366E106 | 46,852,139 | 0.95 | 872967.0 |
| TBLA | REDUCED | Taboola.com Ltd | ORD SHS | M8744T106 | 42,117,050 | 0.85 | 8423410.0 |
| PVLA | UNCHANGED | Palvella Therapeutics Inc | COM | 697947109 | 39,348,858 | 0.8 | 257485.0 |
| SLN | ADDED | Silence Therapeutics PLC | ADS | 82686Q101 | 36,359,589 | 0.74 | 3311438.0 |
| DNLI | UNCHANGED | Denali Therapeutics Inc | COM | 24823R105 | 35,918,314 | 0.73 | 1396513.0 |
| RELY | UNCHANGED | Remitly Global Inc | COM | 75960P104 | 34,584,703 | 0.7 | 1543271.0 |
| CGEM | ADDED | Cullinan Therapeutics Inc | COM | 230031106 | 34,478,996 | 0.7 | 1893410.0 |
| - | Capital One Finl Corp | COM | 14040H105 | 34,429,401 | 0.7 | 171615.0 | |
| TRVI | UNCHANGED | Trevi Therapeutics Inc | COM | 89532M101 | 33,325,070 | 0.67 | 1786867.0 |
| GOOGL | ADDED | Alphabet Inc | CAP STK CL A | 02079K305 | 32,163,300 | 0.65 | 90000.0 |
| - | Dbv Technologies SA | SPONSORED ADS | 23306J309 | 30,460,737 | 0.62 | 1857362.0 | |
| ABSI | ADDED | Absci Corp | COM | 00091E109 | 28,682,515 | 0.58 | 2474764.0 |
| SION | ADDED | Sionna Therapeutics Inc | COM | 829401108 | 26,856,555 | 0.54 | 610515.0 |
| RAPP | UNCHANGED | Rapport Therapeutics Inc | COM | 75383L102 | 26,730,013 | 0.54 | 641469.0 |
| AMLX | ADDED | Amylyx Pharmaceuticals Inc | COM | 03237H101 | 26,591,325 | 0.54 | 1480586.0 |
| ANNX | ADDED | Annexon Inc | COM | 03589W102 | 25,458,869 | 0.52 | 4458646.0 |
| MNPR | UNCHANGED | Monopar Therapeutics Inc | COM NEW | 61023L207 | 25,010,226 | 0.51 | 270118.0 |
| ORKA | NEW | Oruka Therapeutics Inc | COM | 687604108 | 23,792,500 | 0.48 | 250000.0 |
| SPTX | NEW | Seaport Therapeutics Inc | COMMON STOCK | 81221K108 | 23,790,264 | 0.48 | 1095316.0 |
| DMRA | UNCHANGED | Damora Therapeutics Inc | COM NEW | 36322Q206 | 23,409,000 | 0.47 | 900000.0 |
| TYRA | NEW | Tyra Biosciences Inc | COM | 90240B106 | 23,156,500 | 0.47 | 725000.0 |
| ZURA | UNCHANGED | Zura Bio Ltd | CLASS A ORD SHS | G9TY5A101 | 22,035,709 | 0.45 | 3734866.0 |
| ORIC | UNCHANGED | Oric Pharmaceuticals Inc | COM | 68622P109 | 21,558,382 | 0.44 | 1990617.0 |
| TSM | ADDED | Taiwan Semiconductor Manufacturing Co Ltd | SPONSORED ADS | 874039100 | 21,347,379 | 0.43 | 44700.0 |
| RCUS | REDUCED | Arcus Biosciences Inc | COM | 03969F109 | 20,823,507 | 0.42 | 675430.0 |
| NVDA | ADDED | NVIDIA Corp | COM | 67066G104 | 19,008,550 | 0.38 | 95000.0 |
| RZLT | UNCHANGED | Rezolute Inc | COM NEW | 76200L309 | 17,307,092 | 0.35 | 3328287.0 |
| MPLT | UNCHANGED | MapLight Therapeutics Inc | COM | 56565P103 | 16,128,000 | 0.33 | 450000.0 |
| NMRA | UNCHANGED | Neumora Therapeutics Inc | COM | 640979100 | 14,446,297 | 0.29 | 8497822.0 |
| - | Nebius Group NV | SHS CLASS A | N97284108 | 14,360,840 | 0.29 | 52000.0 | |
| MSFT | ADDED | Microsoft Corp | COM | 594918104 | 13,988,250 | 0.28 | 37500.0 |
| CTMX | UNCHANGED | CytomX Therapeutics Inc | COM | 23284F105 | 12,966,416 | 0.26 | 3457711.0 |
| GENB | UNCHANGED | Generate Biomedicines Inc | COM SHS | 370920100 | 12,418,075 | 0.25 | 736104.0 |
| IKT | UNCHANGED | Inhibikase Therapeutics Inc | COM NEW | 45719W205 | 11,875,500 | 0.24 | 5850000.0 |
| ADAG | NEW | Adagene Inc | ADS | 005329107 | 11,199,997 | 0.23 | 2666666.0 |
| ORIC | UNCHANGED | Oric Pharmaceuticals Inc | COM | 68622P109 | 10,912,037 | 0.22 | 1007575.0 |
| ENGN | NEW | enGene Therapeutics Inc | COM | 29286X101 | 10,824,025 | 0.22 | 6256662.0 |
| WHWK | ADDED | Whitehawk Therapeutics Inc | COM | 00032Q104 | 10,703,927 | 0.22 | 2337102.0 |
| DDOG | REDUCED | Datadog Inc | CL A COM | 23804L103 | 10,414,400 | 0.21 | 40000.0 |
| NOW | ADDED | ServiceNow Inc | COM | 81762P102 | 9,928,000 | 0.2 | 100000.0 |
| AVGO | ADDED | Broadcom Inc | COM | 11135F101 | 9,443,750 | 0.19 | 25000.0 |
| IONQ | UNCHANGED | IONQ Inc | COM | 46222L108 | 9,054,200 | 0.18 | 170000.0 |
| MSFT | ADDED | Microsoft Corp | COM | 594918104 | 8,952,480 | 0.18 | 24000.0 |
| FROG | REDUCED | Jfrog Ltd | ORD SHS | M6191J100 | 8,679,040 | 0.18 | 95500.0 |
| OCS | NEW | Oculis Holding AG | ORDINARY SHARES | H5870P102 | 8,668,750 | 0.18 | 625000.0 |
| IREN | ADDED | IREN Ltd | ORDINARY SHARES | Q4982L109 | 8,002,750 | 0.16 | 175000.0 |
| AMZN | REDUCED | Amazon.com Inc | COM | 023135106 | 7,746,050 | 0.16 | 32500.0 |
| CRWD | REDUCED | CrowdStrike Holdings Inc | CL A | 22788C105 | 7,631,400 | 0.15 | 10000.0 |
| DSGN | NEW | Design Therapeutics Inc | COM | 25056L103 | 7,570,878 | 0.15 | 523212.0 |
| PDD | ADDED | PDD Holdings Inc | SPONSORED ADS | 722304102 | 7,246,600 | 0.15 | 95000.0 |
| MSLE | UNCHANGED | Satellos Bioscience Inc | COM | 80401L803 | 6,935,875 | 0.14 | 892074.0 |
| DT | ADDED | Dynatrace, Inc | COM NEW | 268150109 | 6,806,050 | 0.14 | 155000.0 |
| AAPL | NEW | Apple Inc | COM | 037833100 | 6,655,280 | 0.13 | 23000.0 |
| TENX | UNCHANGED | Tenax Therapeutics Inc | COM NEW | 88032L605 | 6,214,902 | 0.13 | 427141.0 |
| VTVT | UNCHANGED | vTv Therapeutics Inc | CL A NEW | 918385204 | 6,136,950 | 0.12 | 163000.0 |
| ELOX | NEW | Eloxx Pharmaceuticals Inc | COM NEW | 29014R301 | 5,552,000 | 0.11 | 400000.0 |
| AGMB | UNCHANGED | Agomab Therapeutics NV | SPONSORED ADS | 00860C102 | 5,338,025 | 0.11 | 411250.0 |
| BABA | NEW | Alibaba Group Holding Ltd | SPONSORED ADS | 01609W102 | 4,799,000 | 0.1 | 50000.0 |
| KRRO | UNCHANGED | Korro Bio Inc | COM | 500946108 | 4,582,923 | 0.09 | 347718.0 |
| CLBT | UNCHANGED | Cellebrite DI Ltd | ORDINARY SHARES | M2197Q107 | 4,548,542 | 0.09 | 311544.0 |
| IVVD | ADDED | Invivyd Inc | COM | 00534A102 | 4,362,000 | 0.09 | 5000000.0 |
| OUST | NEW | Ouster Inc | COM NEW | 68989M202 | 4,220,100 | 0.09 | 67500.0 |
| PALI | NEW | Palisade Bio Inc | COM | 696389402 | 4,180,000 | 0.08 | 2000000.0 |
| AEVA | ADDED | Aeva Technologies Inc | COM NEW | 00835Q202 | 4,177,582 | 0.08 | 145459.0 |
| SEER | UNCHANGED | Seer Inc | COM CL A | 81578P106 | 4,081,397 | 0.08 | 2458673.0 |
| NBP | REDUCED | NovaBridge Biosciences | SPONSORED ADS | 44975P103 | 3,909,241 | 0.08 | 2004739.0 |
| GTLB | ADDED | GitLab Inc | CLASS A COM | 37637K108 | 3,816,250 | 0.08 | 125000.0 |
| ODTX | NEW | Odyssey Therapeutics Inc | COMMON STOCK | 67613T104 | 3,742,000 | 0.08 | 200000.0 |
| FHTX | UNCHANGED | Foghorn Therapeutics Inc | COM | 344174107 | 3,517,114 | 0.07 | 720720.0 |
| AGEN | UNCHANGED | Agenus Inc | COM NEW | 00847G804 | 3,256,605 | 0.07 | 1064250.0 |
| MNDY | ADDED | monday.com Ltd | SHS | M7S64H106 | 3,076,575 | 0.06 | 42500.0 |
| ZTS | NEW | Zoetis Inc | CL A | 98978V103 | 2,515,100 | 0.05 | 35000.0 |
| WK | REDUCED | Workiva Inc | COM CL A | 98139A105 | 2,182,950 | 0.04 | 45000.0 |
| NFLX | NEW | Netflix Inc | COM | 64110L106 | 1,784,925 | 0.04 | 25000.0 |
| KLRS | UNCHANGED | Kalaris Therapeutics Inc | COM | 482929106 | 1,773,698 | 0.04 | 435798.0 |
| QNT | NEW | Quantinuum Inc | CL A COM | 74768A104 | 1,634,800 | 0.03 | 20000.0 |
| RANI | UNCHANGED | Rani Therapeutics Holdings Inc | COM CL A | 753018100 | 1,520,800 | 0.03 | 2000000.0 |
| TSLA | REDUCED | Tesla Inc | COM | 88160R101 | 1,472,100 | 0.03 | 3500.0 |
| BEKE | UNCHANGED | KE Holdings Inc | SPONSORED ADS | 482497104 | 1,453,000 | 0.03 | 100000.0 |
| ENTX | NEW | Entera Bio Ltd | SHS | M40527109 | 1,303,529 | 0.03 | 736457.0 |
| MDLN | UNCHANGED | Medline Inc | COM CL A | 58507V107 | 986,000 | 0.02 | 25000.0 |
| LITE | NEW | Lumentum Holdings Inc | COM | 55024U109 | 905,253 | 0.02 | 1055.0 |
| FIG | UNCHANGED | Figma Inc | CLASS A COM STK | 316841105 | 904,500 | 0.02 | 50000.0 |
| GOSS | UNCHANGED | Gossamer Bio Inc | COM | 38341P102 | 857,396 | 0.02 | 5208968.0 |
| FOXA | NEW | Fox Corp | CL A COM | 35137L105 | 521,600 | 0.01 | 10000.0 |
| T | NEW | AT&T Inc | COM | 00206R102 | 517,500 | 0.01 | 25000.0 |
| NU | UNCHANGED | Nu Holdings Ltd. | ORD SHS CL A | G6683N103 | 334,000 | 0.01 | 25000.0 |
Quarterly portfolios
| Period | Filed | Value ($) | Positions | Vol % | Beta | Max DD % |
|---|---|---|---|---|---|---|
| 2026-06-30 | 2026-08-13 | 4,941,404,255 | 119 | 13.825837 | 0.215281 | 34.074801 |
| 2026-03-31 | 2026-05-14 | 3,607,379,030 | 102 | 14.051358 | 0.210456 | 33.66224 |
| 2025-12-31 | 2026-02-13 | 3,352,424,599 | 115 | 13.017928 | 0.19824 | 31.060483 |
| 2025-09-30 | 2025-11-13 | 2,556,293,148 | 117 | 12.256921 | 0.199232 | 28.891117 |
| 2025-03-31 | 2025-05-23 | 1,772,780,355 | 117 | 9.608555 | 0.166504 | 21.315468 |
| 2024-12-31 | 2025-02-14 | 2,263,488,311 | 119 | 10.236613 | 0.154189 | 26.00772 |