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Institutional Holdings

URGN

Ownership Summary

Institutions Holding
229
Total Shares Held
51,339,579
Total Value Held
$1,187,658,739
Quarter
2025-12-31

Active Positions

Increased Positions
12
5,052,754 shares
Decreased Positions
14
739,854 shares
Held Positions
7
90,583 shares
New Positions
185
45,456,388 shares
Sold Out Positions
11
2,890,886 shares
Institution Shares Value Change % of Portfolio Reported
RTW INVESTMENTS, LP 4,543,895 $106,418,021 New position 2025-12-31
BlackRock, Inc. 2,601,009 $60,915,631 New position 2025-12-31
MORGAN STANLEY 2,562,901 $60,023,155 New position 2025-12-31
Kynam Capital Management, LP 2,434,207 $89,578,818 ▲ +186,814 4.95% 2026-06-30
Jefferies Financial Group Inc. 2,199,652 $51,515,850 New position 2025-12-31
AMERICAN CENTURY COMPANIES INC 1,358,812 $31,823,425 New position 2025-12-31
ACORN CAPITAL ADVISORS, LLC 1,448,420 $33,921,996 New position 2025-12-31
Point72 Asset Management, L.P. 1,525,549 $56,140,203 New position 0.06% 2026-06-30
FRONTIER CAPITAL MANAGEMENT CO LLC 781,620 $18,305,546 New position 2025-12-31
Opaleye Management Inc. 268,423 $6,286,467 New position 2025-12-31
SILVERARC CAPITAL MANAGEMENT, LLC 1,738,821 $40,723,188 New position 2025-12-31
MENORA MIVTACHIM HOLDINGS LTD. 1,152,531 $26,992,276 New position 2025-12-31
D. E. Shaw & Co., Inc. 962,624 $22,544,654 New position 2025-12-31
STATE STREET CORP 807,421 $18,909,800 New position 2025-12-31
MPM BioImpact LLC 941,378 $22,047,073 New position 2025-12-31
Soleus Capital Management, L.P. 150,000 $3,513,000 New position 2025-12-31
GOLDMAN SACHS GROUP INC 459,722 $10,766,689 New position 2025-12-31
Migdal Insurance & Financial Holdings Ltd. 770,909 $18,055 New position 2025-12-31
ORBIMED ADVISORS LLC 875,487 $20,503,906 New position 2025-12-31
GEODE CAPITAL MANAGEMENT, LLC 475,212 $11,129,464 New position 2025-12-31
Woodline Partners LP 500,726 $11,727,003 New position 2025-12-31
Boxer Capital Management, LLC 500,000 $11,710,000 ▼ -75,000 2025-12-31
BANK OF AMERICA CORP /DE/ 128,630 $3,012,515 ▲ +20,176 2025-12-31
VANGUARD PORTFOLIO MANAGEMENT LLC 456,558 $16,801,334 New position 0.00% 2026-06-30
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 1,125,100 $26,349,842 New position 2025-12-31
NORTHERN TRUST CORP 237,457 $5,561,243 New position 2025-12-31
RICE HALL JAMES & ASSOCIATES, LLC 281,876 $6,601,536 New position 2025-12-31
Hennion & Walsh Asset Management, Inc. 276,696 $10,182,413 ▲ +93,192 0.29% 2026-06-30
SUSQUEHANNA INTERNATIONAL GROUP, LLP 450,625 $10,553,638 New position 2025-12-31
ADAR1 Capital Management, LLC 330,750 $7,746,166 New position 2025-12-31
J. Goldman & Co LP 597,303 $13,988,836 New position 2025-12-31
Privium Fund Management B.V. 214,622 $5,026,447 New position 2025-12-31
FMR LLC 123,563 $2,893,856 New position 2025-12-31
SUPERSTRING CAPITAL MANAGEMENT LP 718,354 $16,823,851 New position 2025-12-31
Parkman Healthcare Partners LLC 168,768 $3,952,547 New position 2025-12-31
AQR CAPITAL MANAGEMENT LLC 153,413 $3,592,933 New position 2025-12-31
TWO SIGMA INVESTMENTS, LP 241,213 $5,649,208 New position 2025-12-31
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 90,989 $2,130,962 New position 2025-12-31
UBS Group AG 235,040 $5,504,637 New position 2025-12-31
Elmind Capital, LP 100,000 $2,342,000 New position 2025-12-31
WELLINGTON MANAGEMENT GROUP LLP 126,034 $2,951,716 New position 2025-12-31
Bank of New York Mellon Corp 98,829 $2,314,566 New position 2025-12-31
VOLORIDGE INVESTMENT MANAGEMENT, LLC 435,490 $10,199,176 New position 2025-12-31
Aisling Capital Management LP 108,000 $2,529,360 New position 2025-12-31
MILLENNIUM MANAGEMENT LLC 618,952 $14,495,856 New position 2025-12-31
Tidal Investments LLC 26,972 $631,684 New position 2025-12-31
ARK Investment Management LLC 121,484 $2,845,155 New position 2025-12-31
Russell Investments Group, Ltd. 47,257 $1,106,777 New position 2025-12-31
Nuveen, LLC 302,601 $7,086,916 New position 2025-12-31
OAK RIDGE INVESTMENTS LLC 88,591 $3,260,149 ▲ +2,188 0.18% 2026-06-30
CITADEL ADVISORS LLC 822,157 $19,254,917 New position 2025-12-31
WELLS FARGO & COMPANY/MN 84,158 $1,970,988 New position 2025-12-31
Informed Momentum Co LLC 160,412 $3,756,849 New position 2025-12-31
Swiss National Bank 77,800 $2,863,040 Unchanged 0.00% 2026-06-30
PANAGORA ASSET MANAGEMENT INC 74,055 $1,734,368 New position 2025-12-31
TRUIST FINANCIAL CORP 72,286 $1,692,938 New position 2025-12-31
VOYA INVESTMENT MANAGEMENT LLC 76,762 $1,797,766 New position 2025-12-31
RENAISSANCE TECHNOLOGIES LLC 244,300 $5,721,506 New position 2025-12-31
Ally Bridge Group (NY) LLC 69,183 $2,545,934 ▼ -132,941 2.25% 2026-06-30
RHUMBLINE ADVISERS 45,760 $1,071,688 New position 2025-12-31
JANE STREET GROUP, LLC 78,500 $1,838,470 New position 2025-12-31
DEUTSCHE BANK AG TAUNUSANLAGE 12 D-60325 51,550 $1,897,040 ▼ -184,642 0.00% 2026-06-30
Atom Investors LP 234,423 $5,490,187 New position 2025-12-31
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 2,272 $53,210 New position 2025-12-31
BNP PARIBAS FINANCIAL MARKETS 9,246 $216,541 New position 2025-12-31
JPMORGAN CHASE & CO 146,271 $3,425,668 New position 2025-12-31
VANGUARD FIDUCIARY TRUST CO 37,207 $1,369,218 New position 0.00% 2026-06-30
Coastal Bridge Advisors, LLC 37,000 $866,540 New position 2025-12-31
Legal & General Group Plc 3,643 $85,319 New position 2025-12-31
STATE OF WISCONSIN INVESTMENT BOARD 35,054 $1,289,987 ▲ +2,938 0.00% 2026-06-30
Focus Partners Wealth 35,277 $826,188 New position 2025-12-31
Schonfeld Strategic Advisors LLC 32,459 $1,194,491 ▼ -125,652 0.00% 2026-06-30
ALGERT GLOBAL LLC 65,935 $1,544 New position 2025-12-31
AMERIPRISE FINANCIAL INC 136,019 $3,185,565 New position 2025-12-31
POLEN CAPITAL MANAGEMENT LLC 29,615 $1,089,832 New position 0.01% 2026-06-30
Cetera Investment Advisers 30,096 $704,848 New position 2025-12-31
VANGUARD ASSET MANAGEMENT, Ltd 26,004 $956,947 New position 0.00% 2026-06-30
Invesco Ltd. 27,066 $633,886 New position 2025-12-31
HighVista Strategies LLC 28,005 $655,877 New position 2025-12-31
MetLife Investment Management, LLC 22,445 $525,662 New position 2025-12-31
Palo Alto Investors LP 24,500 $573,790 New position 2025-12-31
GROUP ONE TRADING LLC 24,246 $892,253 ▼ -2,920 0.00% 2026-06-30
CITIGROUP INC 3,402 $79,675 New position 2025-12-31
ALLIANCEBERNSTEIN L.P. 35,040 $820,637 New position 2025-12-31
JACOBS LEVY EQUITY MANAGEMENT, INC 39,383 $922,350 New position 2025-12-31
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 17,154 $401,747 New position 2025-12-31
Susquehanna Portfolio Strategies, LLC 27,380 $641,240 New position 2025-12-31
XTX Topco Ltd 22,491 $526,739 New position 2025-12-31
FRANKLIN RESOURCES INC 16,745 $392,168 New position 2025-12-31
Jupiter Topco LLC 19,100 $703,644 New position 0.00% 2026-06-30
SIMPLEX TRADING, LLC 22,109 $517,792 New position 2025-12-31
Zurcher Kantonalbank (Zurich Cantonalbank) 18,398 $677,046 ▲ +5,885 0.00% 2026-06-30
Quantinno Capital Management LP 23,514 $550,698 New position 2025-12-31
CAPITAL FUND MANAGEMENT S.A. 17,585 $647,128 New position 0.00% 2026-06-30
GLENMEDE TRUST CO NA 17,206 $633,180 ▲ +6,689 0.00% 2026-06-30
Birchview Capital, LP 16,487 $606,722 New position 0.28% 2026-06-30
Engineers Gate Manager LP 16,378 $602,710 New position 0.01% 2026-06-30
NEW YORK STATE COMMON RETIREMENT FUND 12,737 $298,301 New position 2025-12-31
PARTNERS CAPITAL INVESTMENT GROUP, LLP 15,384 $360,293 New position 2025-12-31
LPL Financial LLC 14,457 $532,018 New position 0.00% 2026-06-30
Verdad Advisers, LP 14,440 $531,392 New position 0.51% 2026-06-30
MML INVESTORS SERVICES, LLC 24,363 $570,581 New position 2025-12-31
MAI Capital Management 2 $47 New position 2025-12-31
DnB Asset Management AS 16,961 $397,227 New position 2025-12-31
State of New Jersey Common Pension Fund D 12,593 $463,422 ▼ -846 0.00% 2026-06-30
Police & Firemen's Retirement System of New Jersey 10,469 $245,184 New position 2025-12-31
Creative Planning 10,576 $247,690 New position 2025-12-31
Integrated Wealth Concepts LLC 11,741 $432,071 ▼ -900 0.00% 2026-06-30
Arax Advisory Partners 14 $328 New position 2025-12-31
Squarepoint Ops LLC 22,831 $534,702 New position 2025-12-31
MANUFACTURERS LIFE INSURANCE COMPANY, THE 55,686 $1,293,016 New position 2025-12-31
ROYAL BANK OF CANADA 8,391 $196,000 New position 2025-12-31
Vanguard Investments Australia, Ltd. 10,820 $398,176 New position 0.00% 2026-06-30
ARIZONA STATE RETIREMENT SYSTEM 10,746 $395,453 ▼ -55 0.00% 2026-06-30
KLP KAPITALFORVALTNING AS 10,200 $375,360 ▼ -4,100 0.00% 2026-06-30
BARCLAYS PLC 57,744 $1,352,364 New position 2025-12-31
Cresset Asset Management, LLC 11,216 $262,679 New position 2025-12-31
INTECH INVESTMENT MANAGEMENT LLC 22,210 $520,158 New position 2025-12-31
Orion Porfolio Solutions, LLC 9,008 $210,967 New position 2025-12-31
Vanguard Global Advisers, LLC 8,472 $311,770 New position 0.00% 2026-06-30
Main Street Financial Solutions, LLC 20,990 $491,576 New position 2025-12-31
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 8,120 $298,816 New position 0.00% 2026-06-30
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 7,642 $294,676 New position 0.00% 2026-06-30
Baader Bank Aktiengesellschaft 8,000 $294,400 New position 0.02% 2026-06-30
FOX RUN MANAGEMENT, L.L.C. 7,957 $292,818 ▼ -17,714 0.05% 2026-06-30
China Universal Asset Management Co., Ltd. 7,627 $178,624 New position 2025-12-31
Mariner, LLC 7,623 $280,527 New position 0.00% 2026-06-30
Kathmere Capital Management, LLC 7,360 $270,848 New position 0.01% 2026-06-30
LOS ANGELES CAPITAL MANAGEMENT LLC 31,569 $626,645 New position 2025-12-31
ProShare Advisors LLC 8,812 $206,378 New position 2025-12-31
DIADEMA PARTNERS LP 21,810 $510,790 New position 2025-12-31
Pictet Asset Management Holding SA 7,000 $257,600 New position 0.00% 2026-06-30
PRUDENTIAL FINANCIAL INC 6,975 $256,680 New position 0.00% 2026-06-30
Jain Global LLC 6,902 $253,994 New position 0.00% 2026-06-30
Brookstone Capital Management 6,000 $220,800 New position 0.00% 2026-06-30
RITHOLTZ WEALTH MANAGEMENT 5,462 $201,002 New position 0.00% 2026-06-30
Allianz Asset Management GmbH 22,000 $515,240 New position 2025-12-31
Ameritas Investment Partners, Inc. 3,082 $72,180 New position 2025-12-31
OSAIC HOLDINGS, INC. 2,915 $68,267 New position 2025-12-31
Tower Research Capital LLC (TRC) 1,469 $34,404 New position 2025-12-31
Mirae Asset Global Investments Co., Ltd. 4,550 $106,562 New position 2025-12-31
Quantbot Technologies LP 200 $4,684 New position 2025-12-31
SG Americas Securities, LLC 2,052,906 $75,547 ▲ +395,060 0.04% 2026-06-30
Persistent Asset Partners Ltd 12,806 $299,916 New position 2025-12-31
Activest Wealth Management 1,001 $23,443 New position 2025-12-31
GF FUND MANAGEMENT CO. LTD. 919 $21,523 New position 2025-12-31
FEDERATED HERMES, INC. 196 $4,590 New position 2025-12-31
JONES FINANCIAL COMPANIES LLLP 1,000 $23,420 New position 2025-12-31
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 403 $9,438 New position 2025-12-31
Rossby Financial, LCC 770 $18,033 New position 2025-12-31
Pinnacle Wealth Planning Services, Inc. 688 $16,113 New position 2025-12-31
NISA INVESTMENT ADVISORS, LLC 595 $21,896 ▲ +131 0.00% 2026-06-30
EverSource Wealth Advisors, LLC 584 $13,677 New position 2025-12-31
State of Wyoming 530 $19,504 New position 0.00% 2026-06-30
Larson Financial Group LLC 140 $3,279 New position 2025-12-31
GAMMA Investing LLC 441 $16,229 ▲ +2 0.00% 2026-06-30
Napier Financial, LLC 400 $14,720 Unchanged 0.00% 2026-06-30
NFSG Corp 350 $12,880 ▼ -650 0.00% 2026-06-30
Sterling Capital Management LLC 584 $13,677 New position 2025-12-31
Allworth Financial LP 35 $820 New position 2025-12-31
Costello Asset Management, INC 200 $4,684 New position 2025-12-31
Rockefeller Capital Management L.P. 112 $2,623 New position 2025-12-31
NewEdge Advisors, LLC 100 $2,342 New position 2025-12-31
ROTHSCHILD INVESTMENT LLC 50 $1,171 New position 2025-12-31
US BANCORP DE U.S. BANCORP 81 $2,981 New position 0.00% 2026-06-30
Optiver Holding B.V. 223 $5,223 New position 2025-12-31
Smartleaf Asset Management LLC 72 $1,668 New position 2025-12-31
PNC FINANCIAL SERVICES GROUP, INC. 63 $1,475 New position 2025-12-31
Essential Partners LLC 48 $1,766 ▼ -70 0.00% 2026-06-30
Annandale Capital, LLC 60,552 $1,418 New position 2025-12-31
Altshuler Shaham Ltd 39 $1,435 New position 0.00% 2026-06-30
Quarry LP 36 $1,325 New position 0.00% 2026-06-30
PRICE T ROWE ASSOCIATES INC /MD/ 616,606 $14,441 New position 2025-12-31
IFP Advisors, Inc 31 $726 ▼ -3 2025-12-31
Farther Finance Advisors, LLC 24 $883 Unchanged 0.00% 2026-06-30
DecisionPoint Financial, LLC 22 $516 New position 2025-12-31
SIGNATUREFD, LLC 16 $589 ▲ +6 0.00% 2026-06-30
True Wealth Design, LLC 16 $589 Unchanged 0.00% 2026-06-30
Jackson Creek Investment Advisors LLC 14,134 $540 New position 0.18% 2026-06-30
NATIONAL BANK OF CANADA /FI/ 11 $405 New position 0.00% 2026-06-30
SHIKIAR ASSET MANAGEMENT INC 8,750 $322 ▼ -2,000 0.08% 2026-06-30
ACADIAN ASSET MANAGEMENT LLC 8,113 $297 New position 0.00% 2026-06-30
SBI Securities Co., Ltd. 18 $422 New position 2025-12-31
Silver Grove Financial Group, Inc. 4 $147 New position 0.00% 2026-06-30
Hughes Financial Services, LLC 3 $110 Unchanged 0.00% 2026-06-30
Keating Financial Advisory Services, Inc. 2 $74 New position 0.00% 2026-06-30
KBC Group NV 1,340 $49 Unchanged 0.00% 2026-06-30
Clearstead Advisors, LLC 1 $37 New position 0.00% 2026-06-30
Covestor Ltd 14 $1 ▲ +8 0.00% 2026-06-30
TORONTO DOMINION BANK 0 $0 Sold out 2026-06-30
Paradigm Biocapital Advisors LP 4,473,648 $104,772,836 New position 2025-12-31
TCG Crossover Management, LLC 717,347 $16,800,267 New position 2025-12-31
TANG CAPITAL MANAGEMENT LLC 350,000 $8,197,000 New position 2025-12-31
Vestal Point Capital, LP 0 $0 Sold out 2026-06-30
Trexquant Investment LP 0 $0 Sold out 2026-06-30
HRT FINANCIAL LP 130,899 $3,065 New position 2025-12-31
BENDER ROBERT & ASSOCIATES 0 $0 Sold out 2026-06-30
Man Group plc 0 $0 Sold out 2026-06-30
MEITAV INVESTMENT HOUSE LTD 35,517 $831,727 New position 2025-12-31
Kranot Hishtalmut Le Morim Tichoniim Havera Menahelet LTD 21,823 $511,095 New position 2025-12-31
Caption Management, LLC 1,000,000 $23,420,000 New position 2025-12-31
QUADRANT CAPITAL GROUP LLC 688 $16,113 New position 2025-12-31
Advisory Services Network, LLC 0 $0 Sold out 2026-06-30
Sound Income Strategies, LLC 0 $0 Sold out 2026-06-30
TWIN PEAKS WEALTH ADVISORS, LLC 0 $0 Sold out 2026-06-30
Root Financial Partners, LLC 0 $0 Sold out 2026-06-30
JPL Wealth Management, LLC 0 $0 Sold out 2026-06-30
NOMURA ASSET MANAGEMENT CO LTD 0 $0 Sold out 2025-12-31
VANGUARD GROUP INC 439,751 $10,298,969 New position 2025-12-31
DEUTSCHE BANK AG\ 366,680 $8,587,645 New position 2025-12-31
TD ASSET MANAGEMENT INC 80,188 $1,878,003 New position 2025-12-31
NEOS Investment Management LLC 53,576 $1,254,750 New position 2025-12-31
ExodusPoint Capital Management, LP 35,393 $828,904 New position 2025-12-31
DARK FOREST CAPITAL MANAGEMENT LP 31,516 $738,105 New position 2025-12-31
Jump Financial, LLC 17,900 $419,218 New position 2025-12-31
Cinctive Capital Management LP 16,991 $397,929 New position 2025-12-31
OPPENHEIMER & CO INC 16,962 $397,250 New position 2025-12-31
MARSHALL WACE, LLP 16,300 $381,746 New position 2025-12-31
Vivaldi Capital Management LP 15,661 $366,781 New position 2025-12-31
WINTON GROUP Ltd 13,188 $308,863 New position 2025-12-31
FARALLON CAPITAL MANAGEMENT LLC 11,000 $257,620 Unchanged 2025-12-31
STRS OHIO 3,800 $88,996 New position 2025-12-31
CIBC Private Wealth Group LLC 575 $13,467 New position 2025-12-31
Aster Capital Management (DIFC) Ltd 298 $6,979 New position 2025-12-31
Parkside Financial Bank & Trust 45 $1,054 New position 2025-12-31
US BANCORP \DE\ 17 $398 New position 2025-12-31
CWM, LLC 7,778 $182 New position 2025-12-31
AMALGAMATED BANK 1,159 $27 New position 2025-12-31
Daiwa Securities Group Inc. 160 $4 New position 2025-12-31