← All institutions
Institutional Holdings
MLTXOwnership Summary
Institutions Holding
208
Total Shares Held
70,725,638
Total Value Held
$974,544,805
Quarter
2025-12-31
Active Positions
Increased Positions
17
2,894,426 shares
Decreased Positions
15
2,536,298 shares
Held Positions
5
20,566 shares
New Positions
163
65,274,348 shares
Sold Out Positions
8
838,252 shares
| Institution | Shares | Value | Change | % of Portfolio | Reported |
|---|---|---|---|---|---|
| BVF INC/IL | 19,751,284 | $260,321,923 | New position | 2025-12-31 | |
| Deep Track Capital, LP | 4,610,071 | $60,760,736 | New position | 2025-12-31 | |
| D. E. Shaw & Co., Inc. | 2,480,767 | $32,696,509 | New position | 2025-12-31 | |
| Cormorant Asset Management, LP | 4,355,433 | $57,404,607 | New position | 2025-12-31 | |
| Jupiter Topco LLC | 3,085,906 | $60,082,590 | New position | 0.02% | 2026-06-30 |
| Logos Global Management LP | 1,750,000 | $23,065,000 | New position | 2025-12-31 | |
| Weiss Asset Management LP | 332,961 | $4,388,426 | New position | 2025-12-31 | |
| CITADEL ADVISORS LLC | 2,295,290 | $30,251,922 | New position | 2025-12-31 | |
| TWO SIGMA INVESTMENTS, LP | 784,811 | $10,343,809 | New position | 2025-12-31 | |
| MPM BIOIMPACT LLC | 1,606,967 | $31,287,647 | ▼ -204,115 | 1.91% | 2026-06-30 |
| JPMORGAN CHASE & CO | 837,739 | $11,041,400 | New position | 2025-12-31 | |
| Vivo Capital, LLC | 1,000,000 | $13,180,000 | New position | 2025-12-31 | |
| JANE STREET GROUP, LLC | 1,721,148 | $22,684,731 | New position | 2025-12-31 | |
| Point72 Asset Management, L.P. | 772,500 | $10,181,550 | New position | 2025-12-31 | |
| BlackRock, Inc. | 286,593 | $3,777,296 | New position | 2025-12-31 | |
| BALYASNY ASSET MANAGEMENT L.P. | 1,571,071 | $20,706,716 | New position | 2025-12-31 | |
| GREAT POINT PARTNERS LLC | 855,813 | $16,662,679 | ▲ +355,813 | 3.15% | 2026-06-30 |
| Candriam S.C.A. | 134,329 | $1,770,532 | New position | 2025-12-31 | |
| BANK OF AMERICA CORP /DE/ | 13,533 | $178,364 | ▲ +9,001 | 2025-12-31 | |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 750,777 | $14,617,628 | ▲ +680,637 | 0.01% | 2026-06-30 |
| Trails Edge Capital Partners, LP | 750,000 | $14,602,500 | New position | 2.32% | 2026-06-30 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,234,036 | $16,264,594 | New position | 2025-12-31 | |
| RENAISSANCE TECHNOLOGIES LLC | 134,472 | $1,772,341 | New position | 2025-12-31 | |
| MILLENNIUM MANAGEMENT LLC | 802,722 | $10,579,876 | New position | 2025-12-31 | |
| MORGAN STANLEY | 1,044,581 | $13,767,578 | New position | 2025-12-31 | |
| Qube Research & Technologies Ltd | 496,242 | $9,661,832 | ▲ +453,325 | 0.01% | 2026-06-30 |
| Caption Management, LLC | 455,800 | $8,874,426 | New position | 0.04% | 2026-06-30 |
| ALGERT GLOBAL LLC | 221,616 | $2,921 | New position | 2025-12-31 | |
| Rhenman & Partners Asset Management AB | 364,000 | $4,797,520 | New position | 2025-12-31 | |
| Trexquant Investment LP | 184,319 | $2,429,324 | New position | 2025-12-31 | |
| AQR CAPITAL MANAGEMENT LLC | 32,886 | $433,437 | New position | 2025-12-31 | |
| BNP PARIBAS FINANCIAL MARKETS | 11,310 | $149,066 | New position | 2025-12-31 | |
| Jump Financial, LLC | 425,559 | $5,608,868 | New position | 2025-12-31 | |
| UBS Group AG | 239,020 | $3,150,284 | New position | 2025-12-31 | |
| J. Goldman & Co LP | 469,867 | $6,192,847 | New position | 2025-12-31 | |
| Granahan Investment Management, LLC | 198,307 | $2,613,686 | New position | 2025-12-31 | |
| Boxer Capital Management, LLC | 275,000 | $3,624,500 | ▲ +25,000 | 2025-12-31 | |
| Walleye Capital LLC | 137,152 | $1,807,663 | New position | 2025-12-31 | |
| Susquehanna Portfolio Strategies, LLC | 253,974 | $3,347,377 | New position | 2025-12-31 | |
| Holocene Advisors, LP | 250,000 | $4,867,500 | ▼ -350,000 | 0.01% | 2026-06-30 |
| Burkehill Global Management, LP | 250,000 | $4,867,500 | New position | 0.18% | 2026-06-30 |
| Y-Intercept (Hong Kong) Ltd | 95,972 | $1,264,911 | New position | 2025-12-31 | |
| ACUTA CAPITAL PARTNERS, LLC | 59,280 | $781,310 | New position | 2025-12-31 | |
| Verition Fund Management LLC | 207,102 | $4,032,276 | New position | 0.02% | 2026-06-30 |
| GROUP ONE TRADING LLC | 30,476 | $401,674 | New position | 2025-12-31 | |
| HighVista Strategies LLC | 187,946 | $3,659,308 | ▼ -6,009 | 0.83% | 2026-06-30 |
| RICE HALL JAMES & ASSOCIATES, LLC | 127,465 | $1,679,989 | New position | 2025-12-31 | |
| CONGRESS ASSET MANAGEMENT CO | 180,448 | $3,513,323 | ▲ +1,893 | 0.02% | 2026-06-30 |
| Kalehua Capital Management LLC | 175,734 | $2,316,174 | New position | 2025-12-31 | |
| Voleon Capital Management LP | 499,099 | $6,578,125 | New position | 2025-12-31 | |
| Exome Asset Management LLC | 166,493 | $3,241,619 | ▼ -48,883 | 2.00% | 2026-06-30 |
| Longaeva Partners L.P. | 161,557 | $3,145,515 | ▼ -248,443 | 0.07% | 2026-06-30 |
| XTX Topco Ltd | 22,973 | $302,784 | New position | 2025-12-31 | |
| FMR LLC | 156,276 | $2,059,717 | New position | 2025-12-31 | |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 130,327 | $2,537,467 | New position | 0.00% | 2026-06-30 |
| GOLDMAN SACHS GROUP INC | 270,665 | $3,567,365 | New position | 2025-12-31 | |
| TD ASSET MANAGEMENT INC | 126,744 | $1,670,486 | New position | 2025-12-31 | |
| Engineers Gate Manager LP | 111,590 | $2,172,657 | New position | 0.03% | 2026-06-30 |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 110,000 | $2,142,000 | New position | 0.00% | 2026-06-30 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 85,570 | $1,129,986 | New position | 2025-12-31 | |
| Quadrature Capital Ltd | 50,217 | $661,860 | New position | 2025-12-31 | |
| SIMPLEX TRADING, LLC | 28,972 | $381,850 | New position | 2025-12-31 | |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 105,739 | $2,058,738 | ▲ +31,577 | 0.00% | 2026-06-30 |
| Polymer Capital Management (HK) LTD | 100,463 | $1,956,015 | New position | 0.10% | 2026-06-30 |
| HEIGHTS CAPITAL MANAGEMENT, INC | 100,000 | $1,947,000 | New position | 0.45% | 2026-06-30 |
| Centiva Capital, LP | 117,991 | $1,555,121 | New position | 2025-12-31 | |
| Ghisallo Capital Management LLC | 100,000 | $1,947,000 | New position | 0.04% | 2026-06-30 |
| SummitTX Capital, L.P. | 99,371 | $1,934,753 | New position | 0.05% | 2026-06-30 |
| Jain Global LLC | 70,611 | $930,653 | New position | 2025-12-31 | |
| STATE STREET CORP | 50,973 | $671,824 | New position | 2025-12-31 | |
| Swiss National Bank | 61,500 | $810,570 | New position | 2025-12-31 | |
| Squarepoint Ops LLC | 121,640 | $1,603,215 | New position | 2025-12-31 | |
| IMC-Chicago, LLC | 36,468 | $480,648 | New position | 2025-12-31 | |
| Monashee Investment Management LLC | 75,000 | $1,460,250 | New position | 2.45% | 2026-06-30 |
| GEODE CAPITAL MANAGEMENT, LLC | 72,606 | $956,435 | New position | 2025-12-31 | |
| Mariner, LLC | 20,159 | $265,689 | New position | 2025-12-31 | |
| Lion Point Capital, LP | 67,500 | $889,650 | New position | 2025-12-31 | |
| CAPITAL FUND MANAGEMENT S.A. | 65,394 | $1,273,221 | ▲ +54,134 | 0.01% | 2026-06-30 |
| Headlands Technologies LLC | 57,087 | $1,111,484 | ▼ -40,046 | 0.12% | 2026-06-30 |
| Stonepine Capital Management, LLC | 50,000 | $973,500 | New position | 0.55% | 2026-06-30 |
| Nuveen, LLC | 637,434 | $8,401,380 | New position | 2025-12-31 | |
| ExodusPoint Capital Management, LP | 212,996 | $2,807,287 | New position | 2025-12-31 | |
| NORTHERN TRUST CORP | 18,479 | $243,554 | New position | 2025-12-31 | |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 29,296 | $386,121 | New position | 2025-12-31 | |
| VANGUARD ASSET MANAGEMENT, Ltd | 36,195 | $704,717 | New position | 0.00% | 2026-06-30 |
| FRED ALGER MANAGEMENT, LLC | 32,254 | $627,985 | New position | 0.00% | 2026-06-30 |
| Campbell & CO Investment Adviser LLC | 13,448 | $177,245 | New position | 2025-12-31 | |
| Aquatic Capital Management LLC | 28,134 | $547,769 | New position | 0.02% | 2026-06-30 |
| Quantbot Technologies LP | 6,266 | $82,586 | New position | 2025-12-31 | |
| Schonfeld Strategic Advisors LLC | 322,261 | $4,247,398 | New position | 2025-12-31 | |
| ADAR1 Capital Management, LLC | 27,000 | $525,690 | ▼ -450,137 | 0.02% | 2026-06-30 |
| FOX RUN MANAGEMENT, L.L.C. | 71,962 | $948,459 | New position | 2025-12-31 | |
| PRELUDE CAPITAL MANAGEMENT, LLC | 25,997 | $506,162 | ▼ -22,886 | 0.04% | 2026-06-30 |
| IEQ CAPITAL, LLC | 24,855 | $483,927 | New position | 0.00% | 2026-06-30 |
| OPTIMIZE FINANCIAL INC. | 24,335 | $473,802 | ▼ -84 | 0.17% | 2026-06-30 |
| Sound Capital Solutions LLC | 24,335 | $473,802 | New position | 0.11% | 2026-06-30 |
| Graham Capital Management, L.P. | 24,292 | $320,169 | New position | 2025-12-31 | |
| DIMENSIONAL FUND ADVISORS LP | 183,552 | $2,419,216 | New position | 2025-12-31 | |
| Legal & General Group Plc | 16,078 | $211,909 | New position | 2025-12-31 | |
| Entropy Technologies, LP | 30,300 | $399,354 | New position | 2025-12-31 | |
| OMERS ADMINISTRATION Corp | 19,500 | $379,665 | New position | 0.00% | 2026-06-30 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 13,592 | $179,143 | New position | 2025-12-31 | |
| Man Group plc | 17,661 | $343,860 | New position | 0.00% | 2026-06-30 |
| Virtus Investment Advisers, LLC | 17,987 | $237,069 | New position | 2025-12-31 | |
| CAPTRUST FINANCIAL ADVISORS | 17,445 | $339,654 | ▲ +5,999 | 0.00% | 2026-06-30 |
| Vident Advisory, LLC | 15,444 | $203,552 | New position | 2025-12-31 | |
| WINTON GROUP Ltd | 15,500 | $301,785 | ▼ -170 | 0.01% | 2026-06-30 |
| STATE OF WISCONSIN INVESTMENT BOARD | 12,438 | $163,933 | New position | 2025-12-31 | |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 13,489 | $262,631 | New position | 0.06% | 2026-06-30 |
| MERCER GLOBAL ADVISORS INC /ADV | 13,202 | $257,043 | New position | 0.00% | 2026-06-30 |
| KLP KAPITALFORVALTNING AS | 6,800 | $89,624 | New position | 2025-12-31 | |
| Russell Investments Group, Ltd. | 3,426 | $45,154 | New position | 2025-12-31 | |
| ARIZONA STATE RETIREMENT SYSTEM | 11,968 | $233,017 | New position | 0.00% | 2026-06-30 |
| BARCLAYS PLC | 50,251 | $662,308 | New position | 2025-12-31 | |
| Symmetry Investments LP | 11,600 | $225,852 | New position | 0.02% | 2026-06-30 |
| State of New Jersey Common Pension Fund D | 11,596 | $225,774 | ▲ +732 | 0.00% | 2026-06-30 |
| Creative Planning | 11,209 | $218,239 | New position | 0.00% | 2026-06-30 |
| Rock Springs Capital Management LP | 61,700 | $813,206 | New position | 2025-12-31 | |
| WELLS FARGO & COMPANY/MN | 10,000 | $131,800 | New position | 2025-12-31 | |
| Crystal Cove Asset Management, LLC | 10,000 | $194,700 | Unchanged | 0.21% | 2026-06-30 |
| SIG BROKERAGE, LP | 10,000 | $194,700 | Unchanged | 0.00% | 2026-06-30 |
| Vanguard Investments Australia, Ltd. | 8,935 | $173,964 | New position | 0.00% | 2026-06-30 |
| T. Rowe Price Investment Management, Inc. | 7,114 | $94 | New position | 2025-12-31 | |
| Advisors Asset Management, Inc. | 3,992 | $52,615 | New position | 2025-12-31 | |
| Ensign Peak Advisors, Inc | 4,489 | $59,165 | New position | 2025-12-31 | |
| Tower Research Capital LLC (TRC) | 704 | $9,279 | New position | 2025-12-31 | |
| DEUTSCHE BANK AG TAUNUSANLAGE 12 D-60325 | 2,888 | $56,229 | ▲ +836 | 0.00% | 2026-06-30 |
| US BANCORP DE U.S. BANCORP | 2,079 | $40,478 | ▼ -244 | 0.00% | 2026-06-30 |
| Arax Advisory Partners | 2,071 | $40,322 | ▲ +2,066 | 0.00% | 2026-06-30 |
| Integrated Wealth Concepts LLC | 1,998 | $38,903 | New position | 0.00% | 2026-06-30 |
| SIGNATUREFD, LLC | 1,962 | $38,200 | ▼ -305 | 0.00% | 2026-06-30 |
| Allworth Financial LP | 381 | $5,022 | New position | 2025-12-31 | |
| Parallel Advisors, LLC | 1,484 | $19,559 | New position | 2025-12-31 | |
| EverSource Wealth Advisors, LLC | 893 | $11,770 | New position | 2025-12-31 | |
| CITIGROUP INC | 910 | $11,994 | New position | 2025-12-31 | |
| DecisionPoint Financial, LLC | 1,219 | $16,067 | New position | 2025-12-31 | |
| PRICE T ROWE ASSOCIATES INC /MD/ | 959,553 | $12,647 | New position | 2025-12-31 | |
| BNP Paribas Asset Management Holding S.A. | 61,948 | $817 | New position | 2025-12-31 | |
| Farther Finance Advisors, LLC | 883 | $17,316 | ▲ +150 | 0.00% | 2026-06-30 |
| Essential Partners LLC | 710 | $13,824 | ▲ +702 | 0.01% | 2026-06-30 |
| HRT FINANCIAL LP | 635,901 | $8,381 | New position | 2025-12-31 | |
| Caitong International Asset Management Co., Ltd | 7,095 | $93,512 | New position | 2025-12-31 | |
| JONES FINANCIAL COMPANIES LLLP | 514 | $10,229 | ▲ +462 | 0.00% | 2026-06-30 |
| OSAIC HOLDINGS, INC. | 8,985 | $118,422 | New position | 2025-12-31 | |
| Steward Partners Investment Advisory, LLC | 95 | $1,252 | New position | 2025-12-31 | |
| SBI Securities Co., Ltd. | 213 | $2,807 | New position | 2025-12-31 | |
| Nykredit A/S | 289 | $5,627 | New position | 0.00% | 2026-06-30 |
| ROTHSCHILD INVESTMENT LLC | 1 | $13 | New position | 2025-12-31 | |
| NISA INVESTMENT ADVISORS, LLC | 144 | $2,804 | New position | 0.00% | 2026-06-30 |
| Quarry LP | 120 | $2,336 | ▼ -21,130 | 0.00% | 2026-06-30 |
| GSA CAPITAL PARTNERS LLP | 89,236 | $1,176 | New position | 2025-12-31 | |
| ROYAL BANK OF CANADA | 103 | $2,000 | New position | 2025-12-31 | |
| IFP Advisors, Inc | 1 | $13 | ▼ -1,100 | 2025-12-31 | |
| IFG Advisory, LLC | 100 | $1,947 | New position | 0.00% | 2026-06-30 |
| True Wealth Design, LLC | 74 | $1,441 | New position | 0.00% | 2026-06-30 |
| CVA Family Office, LLC | 60 | $1,168 | Unchanged | 0.00% | 2026-06-30 |
| Cornerstone Financial Management LLC | 57 | $1,110 | ▲ +29 | 0.00% | 2026-06-30 |
| Ameritas Advisory Services, LLC | 56 | $1,090 | New position | 0.00% | 2026-06-30 |
| SJS Investment Consulting Inc. | 54 | $1,052 | New position | 0.00% | 2026-06-30 |
| Wealth Enhancement Trust Services, Inc. | 49 | $954 | New position | 0.00% | 2026-06-30 |
| Clearstead Advisors, LLC | 40 | $780 | New position | 0.00% | 2026-06-30 |
| PNC FINANCIAL SERVICES GROUP, INC. | 47 | $620 | New position | 2025-12-31 | |
| Virtu Financial LLC | 12,582 | $166 | New position | 2025-12-31 | |
| GAMMA Investing LLC | 14 | $273 | New position | 0.00% | 2026-06-30 |
| SG Americas Securities, LLC | 9,254 | $180 | ▼ -96 | 0.00% | 2026-06-30 |
| Wilmington Savings Fund Society, FSB | 9 | $175 | New position | 0.00% | 2026-06-30 |
| Larson Financial Group LLC | 7 | $136 | New position | 0.00% | 2026-06-30 |
| HUNTINGTON NATIONAL BANK | 6 | $117 | Unchanged | 0.00% | 2026-06-30 |
| FNY Investment Advisers, LLC | 3,000 | $58 | New position | 0.02% | 2026-06-30 |
| Global Retirement Partners, LLC | 1 | $13 | New position | 2025-12-31 | |
| Smallwood Wealth Investment Management, LLC | 2 | $38 | New position | 0.00% | 2026-06-30 |
| Avion Wealth | 500 | $9 | Unchanged | 0.00% | 2026-06-30 |
| Jefferies Financial Group Inc. | 500,000 | $6,590,000 | New position | 2025-12-31 | |
| Casdin Capital, LLC | 0 | $0 | Sold out | 2026-06-30 | |
| First Turn Management, LLC | 262,643 | $3,461,635 | New position | 2025-12-31 | |
| Ishara Investments LP | 0 | $0 | Sold out | 2026-06-30 | |
| READYSTATE ASSET MANAGEMENT LP | 0 | $0 | Sold out | 2026-06-30 | |
| ALPS ADVISORS INC | 58,169 | $766,667 | New position | 2025-12-31 | |
| Avidity Partners Management LP | 0 | $0 | Sold out | 2026-06-30 | |
| Brevan Howard Capital Management LP | 78,638 | $1,036,449 | New position | 2025-12-31 | |
| AXQ CAPITAL, LP | 0 | $0 | Sold out | 2026-06-30 | |
| Delos Wealth Advisors, LLC | 6,000 | $79,080 | New position | 2025-12-31 | |
| SUMMIT SECURITIES GROUP LLC | 0 | $0 | Sold out | 2026-06-30 | |
| QUADRANT CAPITAL GROUP LLC | 210 | $2,768 | New position | 2025-12-31 | |
| MAI Capital Management | 0 | $0 | Sold out | 2026-06-30 | |
| JANUS HENDERSON GROUP PLC | 2,095,988 | $27,656,562 | New position | 2025-12-31 | |
| Soleus Capital Management, L.P. | 400,000 | $5,272,000 | New position | 2025-12-31 | |
| STEMPOINT CAPITAL LP | 348,401 | $4,591,925 | New position | 2025-12-31 | |
| 683 Capital Management, LLC | 296,900 | $3,913,142 | New position | 2025-12-31 | |
| VANGUARD GROUP INC | 266,150 | $3,507,857 | New position | 2025-12-31 | |
| Eagle Health Investments LP | 187,600 | $2,472,568 | New position | 2025-12-31 | |
| TWO SIGMA ADVISERS, LP | 131,700 | $1,735,806 | New position | 2025-12-31 | |
| AMERIPRISE FINANCIAL INC | 130,964 | $1,726,129 | New position | 2025-12-31 | |
| TUDOR INVESTMENT CORP ET AL | 115,316 | $1,519,865 | ▲ +53,316 | 2025-12-31 | |
| Walleye Trading LLC | 94,590 | $1,246,696 | New position | 2025-12-31 | |
| Woodline Partners LP | 49,168 | $648,034 | New position | 2025-12-31 | |
| DIADEMA PARTNERS LP | 47,200 | $622,096 | New position | 2025-12-31 | |
| Cinctive Capital Management LP | 37,194 | $490,217 | New position | 2025-12-31 | |
| AXIOM INVESTORS LLC /DE | 25,998 | $342,654 | New position | 2025-12-31 | |
| Brooklyn Investment Group | 14,920 | $204,330 | New position | 2025-12-31 | |
| Persistent Asset Partners Ltd | 8,523 | $112,333 | New position | 2025-12-31 | |
| DEUTSCHE BANK AG\ | 2,052 | $27,045 | New position | 2025-12-31 | |
| Kestra Advisory Services, LLC | 2,000 | $26,360 | New position | 2025-12-31 | |
| ACT CAPITAL MANAGEMENT, LLC | 1,500 | $19,770 | New position | 2025-12-31 | |
| US BANCORP \DE\ | 1,328 | $17,503 | New position | 2025-12-31 | |
| WPG Advisers, LLC | 3 | $40 | New position | 2025-12-31 | |
| CWM, LLC | 120 | $2 | New position | 2025-12-31 | |
| BESSEMER GROUP INC | 0 | $0 | Sold out | 2025-12-31 |