Avidity Partners Management LP
CIK 0001791827
Annualised vol
10.244648%
Beta
0.127138
HHI
1565.879389
Top-10 weight
81.942197%
VaR 95%
0.804634%
VaR 99%
1.961235%
Max drawdown
31.937608%
Matched value
60.45242%
Returns of reported holdings
Loading returns…
Position changes vs prior quarter
What the latest 13F shows bought and sold against the quarter before, by share count.
| Ticker | Change | Shares now | Shares before | Share change % | Value now ($) |
|---|---|---|---|---|---|
| CGON | ADDED | 1,398,948 | 1,288,948 | 8.53% | 99,395,255 |
| ORKA | UNCHANGED | 760,424 | 760,424 | 0.0% | 72,369,552 |
| JBIO | ADDED | 1,700,708 | 1,400,708 | 21.42% | 37,789,732 |
| ELVN | ADDED | 550,000 | 400,000 | 37.5% | 27,912,500 |
| CATX | ADDED | 6,299,999 | 6,049,999 | 4.13% | 21,482,997 |
| AKTS | ADDED | 484,200 | 468,566 | 3.34% | 15,605,766 |
| RGEN | UNCHANGED | 77,800 | 77,800 | 0.0% | 10,615,032 |
| IMUX | REDUCED | 669,941 | 6,699,411 | -90.0% | 10,296,993 |
| KPTI | ADDED | 924,487 | 463,741 | 99.35% | 9,032,238 |
| DXCM | ADDED | 100,000 | 90,000 | 11.11% | 6,735,000 |
| TEM | ADDED | 105,000 | 25,000 | 320.0% | 6,082,650 |
| MDT | REDUCED | 70,000 | 100,000 | -30.0% | 5,476,100 |
| VIR | REDUCED | 519,300 | 950,000 | -45.34% | 5,291,667 |
| GPCR | ADDED | 98,000 | 30,000 | 226.67% | 5,259,660 |
| EHC | UNCHANGED | 42,000 | 42,000 | 0.0% | 4,245,360 |
| TENX | ADDED | 265,934 | 215,934 | 23.16% | 3,869,340 |
| NVCT | NEW | 200,000 | - | - | 3,678,000 |
| PODD | NEW | 24,000 | - | - | 3,654,000 |
| BSX | ADDED | 80,000 | 60,000 | 33.33% | 3,414,400 |
| MSLE | UNCHANGED | 387,769 | 387,769 | 0.0% | 3,014,904 |
| ALMR | NEW | 110,000 | - | - | 2,979,900 |
| CNTX | UNCHANGED | 4,998,267 | 4,998,267 | 0.0% | 2,768,540 |
| GILD | UNCHANGED | 20,000 | 20,000 | 0.0% | 2,526,800 |
| PHAT | REDUCED | 200,000 | 249,390 | -19.8% | 2,170,000 |
| KLRA | NEW | 80,000 | - | - | 1,762,400 |
| GMAB | NEW | 50,000 | - | - | 1,373,500 |
| NTLA | UNCHANGED | 75,000 | 75,000 | 0.0% | 1,269,000 |
| CRVS | REDUCED | 80,000 | 115,000 | -30.43% | 1,195,200 |
| ODD | UNCHANGED | 70,000 | 70,000 | 0.0% | 1,059,100 |
| SCYX | REDUCED | 260,206 | 2,081,660 | -87.5% | 1,059,038 |
| EVMN | NEW | 75,000 | - | - | 996,750 |
| ABT | NEW | 10,000 | - | - | 907,400 |
| BBIO | NEW | 10,000 | - | - | 744,800 |
| PTON | REDUCED | 100,000 | 200,000 | -50.0% | 591,000 |
| LEGN | NEW | 15,000 | - | - | 433,200 |
| SVRA | NEW | 50,000 | - | - | 308,000 |
| TRVI | UNCHANGED | 6,660 | 6,660 | 0.0% | 124,209 |
| AVR | CLOSED OUT | 0 | 150,000 | -100.0% | 0 |
| ABUS | CLOSED OUT | 0 | 125,000 | -100.0% | 0 |
| KVUE | CLOSED OUT | 0 | 100,000 | -100.0% | 0 |
| HIMS | CLOSED OUT | 0 | 75,000 | -100.0% | 0 |
| CNC | CLOSED OUT | 0 | 70,000 | -100.0% | 0 |
| PVLA | CLOSED OUT | 0 | 70,000 | -100.0% | 0 |
| MLTX | CLOSED OUT | 0 | 50,000 | -100.0% | 0 |
| ICLR | CLOSED OUT | 0 | 16,000 | -100.0% | 0 |
| RVMD | CLOSED OUT | 0 | 15,000 | -100.0% | 0 |
| NTRA | CLOSED OUT | 0 | 9,000 | -100.0% | 0 |
Holdings (latest quarter)
| Ticker | Change | Issuer | Class | CUSIP | Value ($) | Weight % | Shares |
|---|---|---|---|---|---|---|---|
| - | DIANTHUS THERAPEUTICS INC | COM | 252828108 | 205,115,856 | 32.85 | 2104184.0 | |
| CGON | ADDED | CG ONCOLOGY INC | COM | 156944100 | 99,395,255 | 15.92 | 1398948.0 |
| ORKA | UNCHANGED | ORUKA THERAPEUTICS INC | COM | 687604108 | 72,369,552 | 11.59 | 760424.0 |
| JBIO | ADDED | JADE BIOSCIENCES INC | COM NEW | 008064206 | 37,789,732 | 6.05 | 1700708.0 |
| ELVN | ADDED | ENLIVEN THERAPEUTICS INC | COM | 29337E102 | 27,912,500 | 4.47 | 550000.0 |
| CATX | ADDED | PERSPECTIVE THERAPEUTICS INC | COM NEW | 46489V302 | 21,482,997 | 3.44 | 6299999.0 |
| AKTS | ADDED | AKTIS ONCOLOGY INC | COM | 01021M104 | 15,605,766 | 2.5 | 484200.0 |
| - | PALVELLA THERAPEUTICS INC NE | COM | 697947109 | 10,697,400 | 1.71 | 70000.0 | |
| - | MOBIA MED INC | COMMON STOCK | 60705V103 | 10,696,979 | 1.71 | 798282.0 | |
| RGEN | UNCHANGED | REPLIGEN CORP | COM | 759916109 | 10,615,032 | 1.7 | 77800.0 |
| IMUX | REDUCED | IMMUNIC INC | COM NEW | 4525EP200 | 10,296,993 | 1.65 | 669941.0 |
| - | SENSEONICS HLDGS INC | COM | 81727U303 | 9,088,000 | 1.46 | 1600000.0 | |
| KPTI | ADDED | KARYOPHARM THERAPEUTICS INC | COM NEW | 48576U205 | 9,032,238 | 1.45 | 924487.0 |
| - | TEVA PHARMACEUTICAL INDS LTD | SPONSORED ADS | 881624209 | 6,776,000 | 1.09 | 200000.0 | |
| DXCM | ADDED | DEXCOM INC | COM | 252131107 | 6,735,000 | 1.08 | 100000.0 |
| TEM | ADDED | TEMPUS AI INC | CL A | 88023B103 | 6,082,650 | 0.97 | 105000.0 |
| MDT | REDUCED | MEDTRONIC PLC | SHS | G5960L103 | 5,476,100 | 0.88 | 70000.0 |
| VIR | REDUCED | VIR BIOTECHNOLOGY INC | COM | 92764N102 | 5,291,667 | 0.85 | 519300.0 |
| GPCR | ADDED | STRUCTURE THERAPEUTICS INC | SPONSORED ADS | 86366E106 | 5,259,660 | 0.84 | 98000.0 |
| EHC | UNCHANGED | ENCOMPASS HEALTH CORP | COM | 29261A100 | 4,245,360 | 0.68 | 42000.0 |
| TENX | ADDED | TENAX THERAPEUTICS INC | COM NEW | 88032L605 | 3,869,340 | 0.62 | 265934.0 |
| NVCT | NEW | NUVECTIS PHARMA INC | COM | 67080T108 | 3,678,000 | 0.59 | 200000.0 |
| PODD | NEW | INSULET CORP | COM | 45784P101 | 3,654,000 | 0.59 | 24000.0 |
| BSX | ADDED | BOSTON SCIENTIFIC CORP | COM | 101137107 | 3,414,400 | 0.55 | 80000.0 |
| MSLE | UNCHANGED | SATELLOS BIOSCIENCE INC | COM | 80401L803 | 3,014,904 | 0.48 | 387769.0 |
| ALMR | NEW | ALAMAR BIOSCIENCES INC | COMMON STOCK | 010911105 | 2,979,900 | 0.48 | 110000.0 |
| CNTX | UNCHANGED | CONTEXT THERAPEUTICS INC | COM | 21077P108 | 2,768,540 | 0.44 | 4998267.0 |
| GILD | UNCHANGED | GILEAD SCIENCES INC | COM | 375558103 | 2,526,800 | 0.4 | 20000.0 |
| - | CHARLES RIV LABS INTL INC | COM | 159864107 | 2,267,900 | 0.36 | 10000.0 | |
| PHAT | REDUCED | PHATHOM PHARMACEUTICALS INC | COM | 71722W107 | 2,170,000 | 0.35 | 200000.0 |
| - | AVALYN PHARMACEUTICALS INC | COM SHS | 05348Y105 | 1,975,200 | 0.32 | 60000.0 | |
| KLRA | NEW | KAILERA THERAPEUTICS INC | COMMON STOCK | 482931102 | 1,762,400 | 0.28 | 80000.0 |
| GMAB | NEW | GENMAB A/S | SPONSORED ADS | 372303206 | 1,373,500 | 0.22 | 50000.0 |
| NTLA | UNCHANGED | INTELLIA THERAPEUTICS INC | COM | 45826J105 | 1,269,000 | 0.2 | 75000.0 |
| CRVS | REDUCED | CORVUS PHARMACEUTICALS INC | COM | 221015100 | 1,195,200 | 0.19 | 80000.0 |
| ODD | UNCHANGED | ODDITY TECH LTD | SHS CL A | M7518J104 | 1,059,100 | 0.17 | 70000.0 |
| SCYX | REDUCED | SCYNEXIS INC | COM | 811292309 | 1,059,038 | 0.17 | 260206.0 |
| EVMN | NEW | EVOMMUNE INC | COM SHS | 30054Y107 | 996,750 | 0.16 | 75000.0 |
| ABT | NEW | ABBOTT LABORATORIES | COM | 002824100 | 907,400 | 0.15 | 10000.0 |
| BBIO | NEW | BRIDGEBIO PHARMA INC | COM | 10806X102 | 744,800 | 0.12 | 10000.0 |
| PTON | REDUCED | PELOTON INTERACTIVE INC | CL A COM | 70614W100 | 591,000 | 0.09 | 100000.0 |
| LEGN | NEW | LEGEND BIOTECH CORP | SPONSORED ADS | 52490G102 | 433,200 | 0.07 | 15000.0 |
| - | BRIDGEBIO ONCOLOGY THERAPEUT | COM NEW | 107924102 | 334,160 | 0.05 | 43853.0 | |
| SVRA | NEW | SAVARA INC | COM | 805111101 | 308,000 | 0.05 | 50000.0 |
| TRVI | UNCHANGED | TREVI THERAPEUTICS INC | COM | 89532M101 | 124,209 | 0.02 | 6660.0 |
Quarterly portfolios
| Period | Filed | Value ($) | Positions | Vol % | Beta | Max DD % |
|---|---|---|---|---|---|---|
| 2026-06-30 | 2026-08-14 | 624,441,478 | 45 | 10.244648 | 0.127138 | 31.937608 |
| 2026-03-31 | 2026-05-28 | 493,809,335 | 45 | 9.823327 | 0.139802 | 32.079618 |
| 2025-12-31 | 2026-02-13 | 346,693,009 | 39 | 9.88269 | 0.224132 | 28.186043 |
| 2025-09-30 | 2025-11-14 | 439,394,999 | 43 | 8.472439 | 0.228561 | 22.978508 |
| 2025-03-31 | 2025-05-15 | 524,678,504 | 67 | 11.21879 | 0.407363 | 20.71023 |
| 2024-12-31 | 2025-02-14 | 1,018,174,480 | 63 | 11.205673 | 0.39921 | 24.63474 |