ADAR1 Capital Management, LLC
CIK 0001940272
Annualised vol
8.529435%
Beta
0.145584
HHI
273.068209
Top-10 weight
40.830868%
VaR 95%
0.815685%
VaR 99%
1.584816%
Max drawdown
22.196086%
Matched value
68.252685%
Returns of reported holdings
Loading returns…
Position changes vs prior quarter
What the latest 13F shows bought and sold against the quarter before, by share count.
| Ticker | Change | Shares now | Shares before | Share change % | Value now ($) |
|---|---|---|---|---|---|
| PTGX | REDUCED | 960,863 | 994,119 | -3.35% | 117,782,587 |
| ROIV | REDUCED | 3,157,008 | 3,285,906 | -3.92% | 111,726,513 |
| IMVT | REDUCED | 2,330,716 | 2,679,010 | -13.0% | 89,802,487 |
| ZLAB | ADDED | 3,369,034 | 1,425,367 | 136.36% | 64,011,646 |
| AGIO | ADDED | 1,288,053 | 140,672 | 815.64% | 47,799,647 |
| CYTK | REDUCED | 457,907 | 632,556 | -27.61% | 39,009,097 |
| SEPN | REDUCED | 940,747 | 1,089,818 | -13.68% | 31,505,617 |
| AVR | REDUCED | 3,145,096 | 3,789,132 | -17.0% | 30,979,196 |
| EDIT | NEW | 8,889,000 | - | - | 28,800,360 |
| BBIO | ADDED | 271,689 | 189,292 | 43.53% | 26,562,447 |
| DNLI | REDUCED | 1,029,080 | 1,871,455 | -45.01% | 26,467,938 |
| SYRE | REDUCED | 283,982 | 338,323 | -16.06% | 25,211,922 |
| VIR | REDUCED | 2,456,677 | 2,744,714 | -10.49% | 25,033,539 |
| INSM | ADDED | 228,520 | 35,392 | 545.68% | 24,364,802 |
| CLDX | ADDED | 619,542 | 427,816 | 44.82% | 23,053,158 |
| VKTX | ADDED | 574,038 | 227,717 | 152.08% | 22,393,222 |
| TSHA | ADDED | 3,040,466 | 2,979,429 | 2.05% | 20,705,573 |
| MNPR | REDUCED | 217,595 | 264,278 | -17.66% | 20,147,121 |
| OVID | ADDED | 7,417,479 | 4,544,113 | 63.23% | 19,953,019 |
| ELVN | ADDED | 387,718 | 329,540 | 17.65% | 19,676,689 |
| ENTA | ADDED | 1,344,510 | 51,357 | 2517.97% | 19,602,956 |
| NKTR | ADDED | 244,184 | 161,252 | 51.43% | 17,046,485 |
| RVMD | REDUCED | 87,509 | 133,893 | -34.64% | 16,388,686 |
| RYTM | REDUCED | 136,158 | 211,450 | -35.61% | 15,117,623 |
| IKT | ADDED | 7,387,205 | 6,606,572 | 11.82% | 14,996,026 |
| RLYB | ADDED | 926,352 | 20,535 | 4411.09% | 14,821,632 |
| REGN | ADDED | 22,208 | 12,154 | 82.72% | 13,847,576 |
| STRO | REDUCED | 404,014 | 524,441 | -22.96% | 13,413,265 |
| IONS | ADDED | 166,286 | 160,338 | 3.71% | 13,184,817 |
| SRPT | ADDED | 730,649 | 262,058 | 178.81% | 13,129,763 |
| CTMX | REDUCED | 3,365,118 | 3,410,190 | -1.32% | 12,619,193 |
| VOR | NEW | 680,626 | - | - | 12,530,325 |
| EQ | ADDED | 3,758,569 | 3,726,659 | 0.86% | 12,027,421 |
| ANL | ADDED | 1,017,805 | 117,909 | 763.21% | 11,704,758 |
| CLYM | ADDED | 822,649 | 597,662 | 37.64% | 10,727,343 |
| HLXC | UNCHANGED | 1,000,000 | 1,000,000 | 0.0% | 10,600,000 |
| ZURA | ADDED | 1,759,295 | 630,403 | 179.07% | 10,379,841 |
| OKUR | REDUCED | 2,238,684 | 2,434,941 | -8.06% | 10,208,399 |
| MAZE | ADDED | 339,276 | 50,095 | 577.27% | 10,123,996 |
| XENE | REDUCED | 166,550 | 228,899 | -27.24% | 10,052,958 |
| AMLX | REDUCED | 534,478 | 1,000,604 | -46.58% | 9,599,225 |
| URGN | REDUCED | 252,395 | 395,459 | -36.18% | 9,288,136 |
| FTH | NEW | 361,010 | - | - | 9,025,250 |
| DBVT | REDUCED | 528,295 | 1,012,866 | -47.84% | 8,664,038 |
| SVRA | REDUCED | 1,403,409 | 1,464,535 | -4.17% | 8,644,999 |
| PCVX | REDUCED | 146,034 | 259,137 | -43.65% | 8,488,956 |
| CGON | REDUCED | 118,664 | 185,699 | -36.1% | 8,431,077 |
| MLYS | ADDED | 298,886 | 154,686 | 93.22% | 8,063,944 |
| ASND | ADDED | 28,604 | 25,014 | 14.35% | 7,629,259 |
| AMAN | NEW | 750,000 | - | - | 7,620,000 |
| NRIX | ADDED | 313,236 | 56,070 | 458.65% | 7,599,105 |
| BHVN | ADDED | 501,687 | 44,777 | 1020.41% | 7,465,103 |
| PRME | ADDED | 1,997,552 | 1,973,282 | 1.23% | 7,370,967 |
| IRD | REDUCED | 1,783,781 | 1,849,004 | -3.53% | 7,331,340 |
| LXEO | ADDED | 1,565,950 | 1,467,350 | 6.72% | 7,289,497 |
| DMRA | ADDED | 280,000 | 279,000 | 0.36% | 7,282,800 |
| REPL | REDUCED | 655,784 | 1,682,987 | -61.03% | 7,259,529 |
| LONA | ADDED | 777,100 | 727,481 | 6.82% | 7,141,549 |
| KRRO | UNCHANGED | 540,054 | 540,054 | 0.0% | 7,117,912 |
| RACC | NEW | 650,000 | - | - | 6,955,000 |
| RLAY | NEW | 358,333 | - | - | 6,704,410 |
| JANX | ADDED | 420,881 | 298,546 | 40.98% | 6,464,732 |
| PLRX | ADDED | 5,509,724 | 2,585,126 | 113.13% | 6,281,085 |
| WHWK | ADDED | 1,341,394 | 128,503 | 943.86% | 6,143,585 |
| KRYS | REDUCED | 16,420 | 20,014 | -17.96% | 6,102,821 |
| ABUS | REDUCED | 1,268,147 | 3,133,175 | -59.53% | 6,087,106 |
| PFE | ADDED | 252,400 | 77,400 | 226.1% | 6,077,792 |
| EWTX | ADDED | 143,199 | 90,599 | 58.06% | 5,818,175 |
| ALEC | ADDED | 2,883,583 | 1,050,000 | 174.63% | 5,796,002 |
| FULC | ADDED | 1,565,029 | 130,560 | 1098.7% | 5,728,006 |
| ABOS | REDUCED | 2,111,334 | 2,156,334 | -2.09% | 5,637,262 |
| GLUE | ADDED | 216,752 | 215,752 | 0.46% | 5,245,398 |
| BHAV | UNCHANGED | 495,000 | 495,000 | 0.0% | 5,004,450 |
| BOLD | NEW | 1,968,216 | - | - | 4,920,540 |
| SPRY | REDUCED | 600,999 | 1,361,536 | -55.86% | 4,814,002 |
| PRLD | ADDED | 900,900 | 152,825 | 489.5% | 4,801,797 |
| JATT | NEW | 417,724 | - | - | 4,745,345 |
| RNTX | NEW | 4,500,000 | - | - | 4,680,000 |
| PEPG | ADDED | 2,591,085 | 1,607,638 | 61.17% | 4,663,953 |
| CTNM | ADDED | 278,961 | 276,661 | 0.83% | 4,572,171 |
| CATX | ADDED | 1,210,117 | 749,335 | 61.49% | 4,126,499 |
| BIIB | ADDED | 17,900 | 11,000 | 62.73% | 3,867,474 |
| XNCR | ADDED | 232,560 | 93,665 | 148.29% | 3,744,216 |
| SLN | ADDED | 338,373 | 172,157 | 96.55% | 3,715,336 |
| SPRB | ADDED | 67,717 | 58,600 | 15.56% | 3,656,718 |
| PHVS | UNCHANGED | 105,528 | 105,528 | 0.0% | 3,649,158 |
| ENGN | NEW | 2,104,986 | - | - | 3,641,626 |
| PALI | REDUCED | 1,726,662 | 2,264,845 | -23.76% | 3,608,724 |
| TARA | UNCHANGED | 940,512 | 940,512 | 0.0% | 3,592,756 |
| SGMT | NEW | 437,500 | - | - | 3,381,875 |
| ONC | UNCHANGED | 11,701 | 11,701 | 0.0% | 3,334,434 |
| IVVD | REDUCED | 3,807,427 | 3,822,427 | -0.39% | 3,321,599 |
| TENX | ADDED | 220,462 | 213,462 | 3.28% | 3,207,722 |
| ZNTL | ADDED | 652,750 | 144,636 | 351.31% | 3,165,838 |
| RLMD | UNCHANGED | 451,918 | 451,918 | 0.0% | 3,127,273 |
| BMRN | ADDED | 49,000 | 18,200 | 169.23% | 2,803,780 |
| SMMT | ADDED | 191,869 | 91,869 | 108.85% | 2,795,531 |
| KROS | ADDED | 246,818 | 97,318 | 153.62% | 2,640,953 |
| ELDN | REDUCED | 647,812 | 974,421 | -33.52% | 2,552,379 |
| SNY | REDUCED | 57,100 | 316,939 | -81.98% | 2,435,886 |
| TNGX | ADDED | 76,761 | 50,000 | 53.52% | 2,399,549 |
| ISRG | ADDED | 6,030 | 1,830 | 229.51% | 2,398,010 |
| INO | ADDED | 2,143,910 | 1,470,108 | 45.83% | 2,358,301 |
| OABI | ADDED | 947,412 | 705,190 | 34.35% | 2,330,634 |
| CAPR | UNCHANGED | 90,593 | 90,593 | 0.0% | 2,181,479 |
| DRUG | REDUCED | 30,300 | 33,900 | -10.62% | 2,127,060 |
| ORKA | UNCHANGED | 20,840 | 20,840 | 0.0% | 1,983,343 |
| NVO | REDUCED | 40,000 | 46,000 | -13.04% | 1,917,600 |
| MCK | ADDED | 2,500 | 1,200 | 108.33% | 1,889,000 |
| LXRX | UNCHANGED | 750,000 | 750,000 | 0.0% | 1,800,000 |
| CRVS | ADDED | 117,101 | 87,901 | 33.22% | 1,749,489 |
| CUE | NEW | 55,193 | - | - | 1,741,891 |
| MSLE | UNCHANGED | 222,555 | 222,555 | 0.0% | 1,731,478 |
| KNSA | UNCHANGED | 26,913 | 26,913 | 0.0% | 1,721,086 |
| RCKT | ADDED | 435,500 | 432,500 | 0.69% | 1,489,410 |
| TRAX | NEW | 71,910 | - | - | 1,446,829 |
| EVMN | REDUCED | 104,035 | 184,062 | -43.48% | 1,382,625 |
| CCCC | ADDED | 291,957 | 43,000 | 578.97% | 1,363,439 |
| BCRX | ADDED | 133,000 | 105,000 | 26.67% | 1,330,000 |
| SUPN | REDUCED | 27,842 | 29,642 | -6.07% | 1,294,931 |
| AVTR | ADDED | 130,000 | 80,000 | 62.5% | 1,287,000 |
| INM | NEW | 800,000 | - | - | 1,240,000 |
| PMN | REDUCED | 92,850 | 95,350 | -2.62% | 1,221,906 |
| ARTV | NEW | 118,624 | - | - | 1,150,653 |
| TNYA | ADDED | 1,555,500 | 1,507,800 | 3.16% | 1,149,670 |
| RNAC | NEW | 98,877 | - | - | 1,030,298 |
| TVTX | NEW | 10,000 | - | - | 1,000,000 |
| BNTX | ADDED | 10,600 | 10,000 | 6.0% | 986,330 |
| ACAD | NEW | 38,955 | - | - | 985,562 |
| DYN | REDUCED | 42,821 | 47,463 | -9.78% | 951,054 |
| MPLT | REDUCED | 26,497 | 374,909 | -92.93% | 949,652 |
| GPCR | NEW | 17,500 | - | - | 939,225 |
| KVACF | UNCHANGED | 75,000 | 75,000 | 0.0% | 930,000 |
| WVE | ADDED | 160,000 | 44,900 | 256.35% | 929,600 |
| AURA | NEW | 130,152 | - | - | 924,079 |
| KZIA | NEW | 61,550 | - | - | 866,624 |
| LRMR | ADDED | 272,745 | 52,745 | 417.1% | 831,872 |
| VERA | ADDED | 18,322 | 16,033 | 14.28% | 786,197 |
| RNA | UNCHANGED | 57,688 | 57,688 | 0.0% | 775,904 |
| TXMD | ADDED | 342,447 | 209,210 | 63.69% | 756,808 |
| IDYA | UNCHANGED | 20,000 | 20,000 | 0.0% | 745,400 |
| SIBN | ADDED | 45,000 | 12,580 | 257.71% | 734,400 |
| RPRX | ADDED | 12,500 | 5,000 | 150.0% | 700,875 |
| EOLS | ADDED | 100,000 | 55,859 | 79.02% | 694,000 |
| IBIO | REDUCED | 375,531 | 469,878 | -20.08% | 657,179 |
| FWRD | REDUCED | 48,241 | 78,241 | -38.34% | 651,736 |
| GERN | ADDED | 505,817 | 200,000 | 152.91% | 647,446 |
| SYK | NEW | 2,000 | - | - | 629,680 |
| IOVA | NEW | 146,090 | - | - | 607,734 |
| MGNX | ADDED | 129,822 | 40,000 | 224.56% | 599,778 |
| GILD | REDUCED | 4,648 | 6,351 | -26.81% | 587,228 |
| NTRA | UNCHANGED | 2,147 | 2,147 | 0.0% | 582,803 |
| SPTX | NEW | 26,000 | - | - | 564,720 |
| ASMB | ADDED | 20,447 | 19,947 | 2.51% | 561,884 |
| HELP | ADDED | 81,278 | 31,278 | 159.86% | 537,248 |
| BNTC | ADDED | 40,000 | 17,500 | 128.57% | 535,200 |
| PYPD | UNCHANGED | 103,950 | 103,950 | 0.0% | 528,066 |
| LUNG | ADDED | 404,497 | 374,497 | 8.01% | 525,846 |
| MLTX | REDUCED | 27,000 | 477,137 | -94.34% | 525,690 |
| TRAW | ADDED | 597,729 | 154,098 | 287.89% | 504,065 |
| TECX | ADDED | 14,501 | 13,001 | 11.54% | 498,472 |
| MDGL | UNCHANGED | 895 | 895 | 0.0% | 480,570 |
| ARVN | UNCHANGED | 57,591 | 57,591 | 0.0% | 478,581 |
| KIDS | ADDED | 25,000 | 19,845 | 25.98% | 478,250 |
| COGT | NEW | 12,200 | - | - | 472,140 |
| PHAT | UNCHANGED | 42,900 | 42,900 | 0.0% | 465,465 |
| MIRM | REDUCED | 3,900 | 6,200 | -37.1% | 456,573 |
| KPRX | UNCHANGED | 167,941 | 167,941 | 0.0% | 441,685 |
| KURA | UNCHANGED | 40,000 | 40,000 | 0.0% | 438,800 |
| CNTX | ADDED | 750,969 | 351,094 | 113.89% | 415,962 |
| KLRS | UNCHANGED | 100,000 | 100,000 | 0.0% | 407,000 |
| BCAX | UNCHANGED | 13,705 | 13,705 | 0.0% | 406,901 |
| MRK | UNCHANGED | 3,140 | 3,140 | 0.0% | 403,490 |
| NMRA | ADDED | 210,000 | 33,100 | 534.44% | 357,000 |
| IRTC | NEW | 3,000 | - | - | 356,850 |
| WW | REDUCED | 21,300 | 57,700 | -63.08% | 340,374 |
| CNSP | NEW | 70,000 | - | - | 334,600 |
| CBIO | REDUCED | 18,275 | 50,273 | -63.65% | 328,950 |
| BSX | REDUCED | 7,500 | 10,000 | -25.0% | 320,100 |
| ALT | NEW | 102,823 | - | - | 312,582 |
| VSTM | ADDED | 75,800 | 71,100 | 6.61% | 289,556 |
| ANTX | ADDED | 58,808 | 13,861 | 324.27% | 284,631 |
| PCAP | UNCHANGED | 26,940 | 26,940 | 0.0% | 279,368 |
| PMVP | REDUCED | 201,008 | 231,008 | -12.99% | 269,351 |
| CMPX | REDUCED | 122,132 | 139,000 | -12.14% | 267,469 |
| JD | UNCHANGED | 10,000 | 10,000 | 0.0% | 254,800 |
| RZLT | REDUCED | 48,679 | 58,679 | -17.04% | 253,131 |
| ANAB | UNCHANGED | 3,698 | 3,698 | 0.0% | 249,615 |
| NGNE | NEW | 7,800 | - | - | 245,310 |
| RXST | ADDED | 50,000 | 43,250 | 15.61% | 241,000 |
| COYA | UNCHANGED | 40,900 | 40,900 | 0.0% | 239,265 |
| BCYC | REDUCED | 50,638 | 71,298 | -28.98% | 214,705 |
| SCYX | NEW | 49,387 | - | - | 201,005 |
| PSNL | REDUCED | 15,000 | 25,000 | -40.0% | 201,000 |
| QCLS | UNCHANGED | 50,000 | 50,000 | 0.0% | 195,000 |
| CABA | NEW | 50,000 | - | - | 155,500 |
| OGN | UNCHANGED | 10,000 | 10,000 | 0.0% | 135,400 |
| NEUP | UNCHANGED | 30,000 | 30,000 | 0.0% | 131,100 |
| STIM | UNCHANGED | 100,000 | 100,000 | 0.0% | 130,000 |
| CMMB | UNCHANGED | 80,000 | 80,000 | 0.0% | 129,600 |
| STI | UNCHANGED | 13,500 | 13,500 | 0.0% | 125,415 |
| VYGR | UNCHANGED | 35,000 | 35,000 | 0.0% | 122,500 |
| TRDA | REDUCED | 15,500 | 30,500 | -49.18% | 114,080 |
| VERU | UNCHANGED | 35,000 | 35,000 | 0.0% | 109,550 |
| CLNN | NEW | 15,000 | - | - | 92,325 |
| VTGN | REDUCED | 351,141 | 751,141 | -53.25% | 79,358 |
| LGVN | REDUCED | 108,406 | 200,000 | -45.8% | 76,209 |
| BMEA | UNCHANGED | 43,420 | 43,420 | 0.0% | 63,827 |
| LITS | UNCHANGED | 67,292 | 67,292 | 0.0% | 62,070 |
| JSPR | UNCHANGED | 140,000 | 140,000 | 0.0% | 58,940 |
| ARDX | REDUCED | 11,000 | 23,900 | -53.97% | 56,100 |
| GOSS | REDUCED | 212,531 | 287,531 | -26.08% | 34,983 |
| ATYR | UNCHANGED | 50,685 | 50,685 | 0.0% | 30,249 |
| BSAA | UNCHANGED | 100,000 | 100,000 | 0.0% | 16,560 |
| CHRS | UNCHANGED | 10,366 | 10,366 | 0.0% | 14,512 |
| BEAM | CLOSED OUT | 0 | 1,446,375 | -100.0% | 0 |
| GUTS | CLOSED OUT | 0 | 1,428,571 | -100.0% | 0 |
| KPTI | CLOSED OUT | 0 | 341,936 | -100.0% | 0 |
| BCAB | CLOSED OUT | 0 | 228,107 | -100.0% | 0 |
| MREO | CLOSED OUT | 0 | 150,000 | -100.0% | 0 |
| AVBP | CLOSED OUT | 0 | 141,814 | -100.0% | 0 |
| KALA | CLOSED OUT | 0 | 141,480 | -100.0% | 0 |
| BIOA | CLOSED OUT | 0 | 135,560 | -100.0% | 0 |
| ACRS | CLOSED OUT | 0 | 132,426 | -100.0% | 0 |
| SDGR | CLOSED OUT | 0 | 101,500 | -100.0% | 0 |
| QNCX | CLOSED OUT | 0 | 100,100 | -100.0% | 0 |
| LQDA | CLOSED OUT | 0 | 100,000 | -100.0% | 0 |
| ANNX | CLOSED OUT | 0 | 55,000 | -100.0% | 0 |
| ACET | CLOSED OUT | 0 | 53,827 | -100.0% | 0 |
| CGEM | CLOSED OUT | 0 | 50,000 | -100.0% | 0 |
| ALKS | CLOSED OUT | 0 | 46,400 | -100.0% | 0 |
| RGNX | CLOSED OUT | 0 | 44,416 | -100.0% | 0 |
| NUVB | CLOSED OUT | 0 | 43,500 | -100.0% | 0 |
| QTTB | CLOSED OUT | 0 | 35,000 | -100.0% | 0 |
| UPB | CLOSED OUT | 0 | 35,000 | -100.0% | 0 |
| IMUX | CLOSED OUT | 0 | 30,000 | -100.0% | 0 |
| BLTE | CLOSED OUT | 0 | 26,880 | -100.0% | 0 |
| LPCN | CLOSED OUT | 0 | 23,180 | -100.0% | 0 |
| KYTX | CLOSED OUT | 0 | 22,428 | -100.0% | 0 |
| TFX | CLOSED OUT | 0 | 21,186 | -100.0% | 0 |
| SGRY | CLOSED OUT | 0 | 20,000 | -100.0% | 0 |
| ELAN | CLOSED OUT | 0 | 20,000 | -100.0% | 0 |
| JBIO | CLOSED OUT | 0 | 20,000 | -100.0% | 0 |
| LEGN | CLOSED OUT | 0 | 20,000 | -100.0% | 0 |
| NTLA | CLOSED OUT | 0 | 19,517 | -100.0% | 0 |
| SNDX | CLOSED OUT | 0 | 17,500 | -100.0% | 0 |
| BMY | CLOSED OUT | 0 | 17,500 | -100.0% | 0 |
| SXT | CLOSED OUT | 0 | 15,000 | -100.0% | 0 |
| KYNB | CLOSED OUT | 0 | 10,469 | -100.0% | 0 |
| AQST | CLOSED OUT | 0 | 10,000 | -100.0% | 0 |
| DSGN | CLOSED OUT | 0 | 10,000 | -100.0% | 0 |
| ERAS | CLOSED OUT | 0 | 10,000 | -100.0% | 0 |
| GH | CLOSED OUT | 0 | 10,000 | -100.0% | 0 |
| IMMX | CLOSED OUT | 0 | 10,000 | -100.0% | 0 |
| CORT | CLOSED OUT | 0 | 8,000 | -100.0% | 0 |
| UNH | CLOSED OUT | 0 | 5,501 | -100.0% | 0 |
| LLY | CLOSED OUT | 0 | 5,060 | -100.0% | 0 |
| RBRK | CLOSED OUT | 0 | 4,900 | -100.0% | 0 |
| JAZZ | CLOSED OUT | 0 | 3,000 | -100.0% | 0 |
| NBIX | CLOSED OUT | 0 | 2,500 | -100.0% | 0 |
| PANW | CLOSED OUT | 0 | 1,600 | -100.0% | 0 |
Holdings (latest quarter)
| Ticker | Change | Issuer | Class | CUSIP | Value ($) | Weight % | Shares |
|---|---|---|---|---|---|---|---|
| - | ABIVAX SA | SPONSORED ADS | 00370M103 | 240,494,722 | 11.01 | 1804703.0 | |
| PTGX | REDUCED | PROTAGONIST THERAPEUTICS INC | COM | 74366E102 | 117,782,587 | 5.39 | 960863.0 |
| ROIV | REDUCED | ROIVANT SCIENCES LTD | SHS | G76279101 | 111,726,513 | 5.11 | 3157008.0 |
| - | STATE STR SPDR S&P 500 ETF T | TR UNIT | 78462F103 | 96,398,299 | 4.41 | 129087.0 | |
| IMVT | REDUCED | IMMUNOVANT INC | COM | 45258J102 | 89,802,487 | 4.11 | 2330716.0 |
| ZLAB | ADDED | ZAI LAB LTD | ADR | 98887Q104 | 64,011,646 | 2.93 | 3369034.0 |
| AGIO | ADDED | AGIOS PHARMACEUTICALS INC | COM | 00847X104 | 47,799,647 | 2.19 | 1288053.0 |
| - | CRINETICS PHARMACEUTICALS IN | COM | 22663K107 | 45,730,234 | 2.09 | 1222080.0 | |
| - | EA SERIES TRUST | ALPHA ARCH 1-3 | 02072L565 | 39,473,966 | 1.81 | 337125.0 | |
| CYTK | REDUCED | CYTOKINETICS INC | COM NEW | 23282W605 | 39,009,097 | 1.79 | 457907.0 |
| SEPN | REDUCED | SEPTERNA INC | COM | 81734D104 | 31,505,617 | 1.44 | 940747.0 |
| AVR | REDUCED | ANTERIS TECHNOLOGIES GLOBAL | COM | 03675P102 | 30,979,196 | 1.42 | 3145096.0 |
| EDIT | NEW | EDITAS MEDICINE INC | COM | 28106W103 | 28,800,360 | 1.32 | 8889000.0 |
| DNLI | REDUCED | DENALI THERAPEUTICS INC | COM | 24823R105 | 26,467,938 | 1.21 | 1029080.0 |
| SYRE | REDUCED | SPYRE THERAPEUTICS INC | COM NEW | 00773J202 | 25,211,922 | 1.15 | 283982.0 |
| VIR | REDUCED | VIR BIOTECHNOLOGY INC | COM | 92764N102 | 25,033,539 | 1.15 | 2456677.0 |
| - | PRAXIS PRECISION MEDICINES I | COM NEW | 74006W207 | 24,859,162 | 1.14 | 74253.0 | |
| INSM | ADDED | INSMED INC | COM PAR $.01 | 457669307 | 24,364,802 | 1.12 | 228520.0 |
| CLDX | ADDED | CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 | 23,053,158 | 1.05 | 619542.0 |
| VKTX | ADDED | VIKING THERAPEUTICS INC | COM | 92686J106 | 22,393,222 | 1.02 | 574038.0 |
| TSHA | ADDED | TAYSHA GENE THERAPIES INC | COM SHS | 877619106 | 20,705,573 | 0.95 | 3040466.0 |
| MNPR | REDUCED | MONOPAR THERAPEUTICS INC | COM NEW | 61023L207 | 20,147,121 | 0.92 | 217595.0 |
| OVID | ADDED | OVID THERAPEUTICS INC | COM | 690469101 | 19,953,019 | 0.91 | 7417479.0 |
| ELVN | ADDED | ENLIVEN THERAPEUTICS INC | COM | 29337E102 | 19,676,689 | 0.9 | 387718.0 |
| ENTA | ADDED | ENANTA PHARMACEUTICALS INC | COM | 29251M106 | 19,602,956 | 0.9 | 1344510.0 |
| - | ISHARES TR | RUSSELL 2000 ETF | 464287655 | 18,778,125 | 0.86 | 62500.0 | |
| - | STATE STR SPDR S&P 500 ETF T | TR UNIT | 78462F103 | 18,669,250 | 0.85 | 25000.0 | |
| NKTR | ADDED | NEKTAR THERAPEUTICS | COM NEW | 640268306 | 17,046,485 | 0.78 | 244184.0 |
| - | INSPIRE MED SYS INC | COM | 457730109 | 16,711,664 | 0.76 | 374617.0 | |
| RVMD | REDUCED | REVOLUTION MEDICINES INC | COM | 76155X100 | 16,388,686 | 0.75 | 87509.0 |
| - | ESTABLISHMENT LABS HLDGS INC | COM | G31249108 | 15,927,966 | 0.73 | 185619.0 | |
| - | PROTHENA CORP PLC | SHS | G72800108 | 15,218,898 | 0.7 | 1554535.0 | |
| RYTM | REDUCED | RHYTHM PHARMACEUTICALS INC | COM | 76243J105 | 15,117,623 | 0.69 | 136158.0 |
| IKT | ADDED | INHIBIKASE THERAPEUTICS INC | COM NEW | 45719W205 | 14,996,026 | 0.69 | 7387205.0 |
| - | UNIQURE NV | SHS | N90064101 | 14,954,392 | 0.68 | 324672.0 | |
| RLYB | ADDED | RALLYBIO CORP | COM | 75120L209 | 14,821,632 | 0.68 | 926352.0 |
| REGN | ADDED | REGENERON PHARMACEUTICALS | COM | 75886F107 | 13,847,576 | 0.63 | 22208.0 |
| - | INVENTIVA SA | ADS | 46124U107 | 13,633,160 | 0.62 | 3606656.0 | |
| STRO | REDUCED | SUTRO BIOPHARMA INC | COM SHS | 869367201 | 13,413,265 | 0.61 | 404014.0 |
| IONS | ADDED | IONIS PHARMACEUTICALS INC | COM | 462222100 | 13,184,817 | 0.6 | 166286.0 |
| BBIO | ADDED | BRIDGEBIO PHARMA INC | COM | 10806X102 | 13,159,797 | 0.6 | 176689.0 |
| SRPT | ADDED | SAREPTA THERAPEUTICS INC | COM | 803607100 | 13,129,763 | 0.6 | 730649.0 |
| CTMX | REDUCED | CYTOMX THERAPEUTICS INC. | COM | 23284F105 | 12,619,193 | 0.58 | 3365118.0 |
| VOR | NEW | VOR BIOPHARMA INC | COM NEW | 929033207 | 12,530,325 | 0.57 | 680626.0 |
| - | SPDR SERIES TRUST | ST STR BLO 1 ETF | 78468R663 | 12,425,009 | 0.57 | 135585.0 | |
| EQ | ADDED | EQUILLIUM INC | COM | 29446K106 | 12,027,421 | 0.55 | 3758569.0 |
| ANL | ADDED | ADLAI NORTYE LTD | SPONSORED ADS | 00704R109 | 11,704,758 | 0.54 | 1017805.0 |
| CLYM | ADDED | CLIMB BIO INC | COM | 28658R106 | 10,727,343 | 0.49 | 822649.0 |
| - | SPDR SERIES TRUST | ST STR SP BIOT | 78464A870 | 10,666,050 | 0.49 | 67400.0 | |
| HLXC | UNCHANGED | HELIX ACQUISITION CORP III | USD CL A ORD SHS | G4444S107 | 10,600,000 | 0.49 | 1000000.0 |
| ZURA | ADDED | ZURA BIO LTD | CLASS A ORD SHS | G9TY5A101 | 10,379,841 | 0.48 | 1759295.0 |
| OKUR | REDUCED | ONKURE THERAPEUTICS INC | COM CL A | 68277Q105 | 10,208,399 | 0.47 | 2238684.0 |
| MAZE | ADDED | MAZE THERAPEUTICS INC | COM | 578784100 | 10,123,996 | 0.46 | 339276.0 |
| XENE | REDUCED | XENON PHARMACEUTICALS INC | COM | 98420N105 | 10,052,958 | 0.46 | 166550.0 |
| - | TEVA PHARMACEUTICAL INDS LTD | SPONSORED ADS | 881624209 | 9,413,490 | 0.43 | 277848.0 | |
| URGN | REDUCED | UROGEN PHARMA LTD | COM | M96088105 | 9,288,136 | 0.43 | 252395.0 |
| FTH | NEW | FAETH THERAPEUTICS INC | COM NEW | 81728A207 | 9,025,250 | 0.41 | 361010.0 |
| AMLX | REDUCED | AMYLYX PHARMACEUTICALS INC | COM | 03237H101 | 8,879,029 | 0.41 | 494378.0 |
| DBVT | REDUCED | DBV TECHNOLOGIES S A | SPONSORED ADS | 23306J309 | 8,664,038 | 0.4 | 528295.0 |
| SVRA | REDUCED | SAVARA INC | COM | 805111101 | 8,644,999 | 0.4 | 1403409.0 |
| PCVX | REDUCED | VAXCYTE INC | COM | 92243G108 | 8,488,956 | 0.39 | 146034.0 |
| CGON | REDUCED | CG ONCOLOGY INC | COM | 156944100 | 8,431,077 | 0.39 | 118664.0 |
| MLYS | ADDED | MINERALYS THERAPEUTICS INC | COM | 603170101 | 8,063,944 | 0.37 | 298886.0 |
| ASND | ADDED | ASCENDIS PHARMA A/S | ORD SHS | K08588103 | 7,629,259 | 0.35 | 28604.0 |
| AMAN | NEW | AMANAT ACQUISITION CORP | CL A ORD | G0375M101 | 7,620,000 | 0.35 | 750000.0 |
| NRIX | ADDED | NURIX THERAPEUTICS INC | COM | 67080M103 | 7,599,105 | 0.35 | 313236.0 |
| BHVN | ADDED | BIOHAVEN LTD | COM | G1110E107 | 7,465,103 | 0.34 | 501687.0 |
| PRME | ADDED | PRIME MEDICINE INC | COM | 74168J101 | 7,370,967 | 0.34 | 1997552.0 |
| - | PERCEPTIVE CAP SOLUTIONS COR | CL A ORD SHS | G70077105 | 7,340,682 | 0.34 | 674695.0 | |
| IRD | REDUCED | OPUS GENETICS INC | COM | 67577R102 | 7,331,340 | 0.34 | 1783781.0 |
| LXEO | ADDED | LEXEO THERAPEUTICS INC | COM | 52886X107 | 7,289,497 | 0.33 | 1565950.0 |
| DMRA | ADDED | DAMORA THERAPEUTICS INC | COM NEW | 36322Q206 | 7,282,800 | 0.33 | 280000.0 |
| REPL | REDUCED | REPLIMUNE GROUP INC | COM | 76029N106 | 7,259,529 | 0.33 | 655784.0 |
| LONA | ADDED | LEONABIO INC | COM | 04746L203 | 7,141,549 | 0.33 | 777100.0 |
| KRRO | UNCHANGED | KORRO BIO INC | COM | 500946108 | 7,117,912 | 0.33 | 540054.0 |
| RACC | NEW | RESEARCH ALLIANCE CORP III | ORD SHS CL A | G75226103 | 6,955,000 | 0.32 | 650000.0 |
| - | INFLARX NV | COM | N44821101 | 6,720,000 | 0.31 | 3000000.0 | |
| RLAY | NEW | RELAY THERAPEUTICS INC | COM | 75943R102 | 6,704,410 | 0.31 | 358333.0 |
| JANX | ADDED | JANUX THERAPEUTICS INC | COM | 47103J105 | 6,464,732 | 0.3 | 420881.0 |
| PLRX | ADDED | PLIANT THERAPEUTICS INC | COM | 729139105 | 6,281,085 | 0.29 | 5509724.0 |
| WHWK | ADDED | WHITEHAWK THERAPEUTICS INC | COM | 00032Q104 | 6,143,585 | 0.28 | 1341394.0 |
| KRYS | REDUCED | KRYSTAL BIOTECH INC | COM | 501147102 | 6,102,821 | 0.28 | 16420.0 |
| ABUS | REDUCED | ARBUTUS BIOPHARMA CORP | COM | 03879J100 | 6,087,106 | 0.28 | 1268147.0 |
| PFE | ADDED | PFIZER INC | COM | 717081103 | 6,077,792 | 0.28 | 252400.0 |
| - | BRIGHTHOUSE FINL INC | COM | 10922N103 | 6,046,606 | 0.28 | 95523.0 | |
| - | ABIVAX SA | SPONSORED ADS | 00370M103 | 5,916,744 | 0.27 | 44400.0 | |
| EWTX | ADDED | EDGEWISE THERAPEUTICS INC | COM | 28036F105 | 5,818,175 | 0.27 | 143199.0 |
| ALEC | ADDED | ALECTOR INC | COM | 014442107 | 5,796,002 | 0.27 | 2883583.0 |
| FULC | ADDED | FULCRUM THERAPEUTICS INC | COM | 359616109 | 5,728,006 | 0.26 | 1565029.0 |
| - | ARROWHEAD PHARMACEUTICALS IN | COM | 04280A100 | 5,689,398 | 0.26 | 69800.0 | |
| ABOS | REDUCED | ACUMEN PHARMACEUTICALS INC | COM | 00509G209 | 5,637,262 | 0.26 | 2111334.0 |
| - | OAKTREE ACQUISITION CORP III | UNIT 10/04/2029 | G6717R120 | 5,598,665 | 0.26 | 516482.0 | |
| - | GLOBUS MED INC | CL A | 379577208 | 5,538,601 | 0.25 | 70100.0 | |
| GLUE | ADDED | MONTE ROSA THERAPEUTICS INC | COM | 61225M102 | 5,245,398 | 0.24 | 216752.0 |
| - | DISCIPLINED GROWTH | UNIT 99/99/9999 | G2775W127 | 5,020,000 | 0.23 | 500000.0 | |
| BHAV | UNCHANGED | BHAV ACQUISITION CORP | UNIT 03/18/2031 | G1R59W127 | 5,004,450 | 0.23 | 495000.0 |
| BBIO | ADDED | BRIDGEBIO PHARMA INC | NOTE 1.750% 3/0 | 10806XAJ1 | 4,999,140 | 0.23 | 30000.0 |
| BBIO | ADDED | BRIDGEBIO PHARMA INC | NOTE 2.250% 2/0 | 10806XAD4 | 4,941,630 | 0.23 | 45000.0 |
| - | DANAHER CORP DEL | COM | 235851102 | 4,939,527 | 0.23 | 25932.0 | |
| BOLD | NEW | BOUNDLESS BIO INC | COM | 10170A100 | 4,920,540 | 0.23 | 1968216.0 |
| - | AVALYN PHARMACEUTICALS INC | COM SHS | 05348Y105 | 4,821,035 | 0.22 | 146447.0 | |
| SPRY | REDUCED | ARS PHARMACEUTICALS INC | COM | 82835W108 | 4,814,002 | 0.22 | 600999.0 |
| - | ATAIBECKLEY INC | COM SHS | 04650F101 | 4,812,785 | 0.22 | 913242.0 | |
| PRLD | ADDED | PRELUDE THERAPEUTICS INC | COM | 74065P101 | 4,801,797 | 0.22 | 900900.0 |
| JATT | NEW | JATT II ACQUISITION CORP | ORD SHS | G50765109 | 4,745,345 | 0.22 | 417724.0 |
| RNTX | NEW | REIN THERAPEUTICS INC | COM NEW | 00887A204 | 4,680,000 | 0.21 | 4500000.0 |
| PEPG | ADDED | PEPGEN INC | COM | 713317105 | 4,663,953 | 0.21 | 2591085.0 |
| CTNM | ADDED | CONTINEUM THERAPEUTICS INC | CL A | 21217B100 | 4,572,171 | 0.21 | 278961.0 |
| CATX | ADDED | PERSPECTIVE THERAPEUTICS INC | COM NEW | 46489V302 | 4,126,499 | 0.19 | 1210117.0 |
| - | APOGEE THERAPEUTICS INC | COM | 03770N101 | 4,114,630 | 0.19 | 31000.0 | |
| - | NEWAMSTERDAM PHARMA COMPANY | ORDINARY SHARES | N62509109 | 4,020,133 | 0.18 | 118623.0 | |
| - | CORBUS PHARMACEUTICALS HLDGS | COM NEW | 21833P301 | 3,956,362 | 0.18 | 421787.0 | |
| BIIB | ADDED | BIOGEN INC | COM | 09062X103 | 3,867,474 | 0.18 | 17900.0 |
| XNCR | ADDED | XENCOR INC | COM | 98401F105 | 3,744,216 | 0.17 | 232560.0 |
| SLN | ADDED | SILENCE THERAPEUTICS PLC | ADS | 82686Q101 | 3,715,336 | 0.17 | 338373.0 |
| SPRB | ADDED | SPRUCE BIOSCIENCES INC | COM NEW | 85209E208 | 3,656,718 | 0.17 | 67717.0 |
| PHVS | UNCHANGED | PHARVARIS N V | COM | N69605108 | 3,649,158 | 0.17 | 105528.0 |
| ENGN | NEW | ENGENE THERAPEUTICS INC | COM | 29286X101 | 3,641,626 | 0.17 | 2104986.0 |
| PALI | REDUCED | PALISADE BIO INC | COM | 696389402 | 3,608,724 | 0.17 | 1726662.0 |
| TARA | UNCHANGED | PROTARA THERAPEUTICS INC | COM STK | 74365U107 | 3,592,756 | 0.16 | 940512.0 |
| BBIO | ADDED | BRIDGEBIO PHARMA INC | NOTE 2.500% 3/1 | 10806XAB8 | 3,461,880 | 0.16 | 20000.0 |
| SGMT | NEW | SAGIMET BIOSCIENCES INC | COM SER A | 786700104 | 3,381,875 | 0.15 | 437500.0 |
| ONC | UNCHANGED | BEONE MEDICINES LTD | SPONSORED ADS | 07725L102 | 3,334,434 | 0.15 | 11701.0 |
| IVVD | REDUCED | INVIVYD INC | COM | 00534A102 | 3,321,599 | 0.15 | 3807427.0 |
| TENX | ADDED | TENAX THERAPEUTICS INC | COM NEW | 88032L605 | 3,207,722 | 0.15 | 220462.0 |
| ZNTL | ADDED | ZENTALIS PHARMACEUTICALS INC | COM | 98943L107 | 3,165,838 | 0.14 | 652750.0 |
| RLMD | UNCHANGED | RELMADA THERAPEUTICS INC | COM | 75955J402 | 3,127,273 | 0.14 | 451918.0 |
| - | DELCATH SYS INC | COM NEW | 24661P807 | 2,825,007 | 0.13 | 224385.0 | |
| BMRN | ADDED | BIOMARIN PHARMACEUTICAL INC | COM | 09061G101 | 2,803,780 | 0.13 | 49000.0 |
| SMMT | ADDED | SUMMIT THERAPEUTICS INC | COM | 86627T108 | 2,795,531 | 0.13 | 191869.0 |
| KROS | ADDED | KEROS THERAPEUTICS INC | COM | 492327101 | 2,640,953 | 0.12 | 246818.0 |
| ELDN | REDUCED | ELEDON PHARMACEUTICALS INC | COM | 28617K101 | 2,552,379 | 0.12 | 647812.0 |
| SNY | REDUCED | SANOFI SA | SPONSORED ADR | 80105N105 | 2,435,886 | 0.11 | 57100.0 |
| - | AMERICAN EXCEPTIONALISM ACQU | ORD CL A | G0273J101 | 2,427,923 | 0.11 | 205408.0 | |
| TNGX | ADDED | TANGO THERAPEUTICS INC | COM | 87583X109 | 2,399,549 | 0.11 | 76761.0 |
| ISRG | ADDED | INTUITIVE SURGICAL INC | COM NEW | 46120E602 | 2,398,010 | 0.11 | 6030.0 |
| INO | ADDED | INOVIO PHARMACEUTICALS INC | COM SHS | 45773H409 | 2,358,301 | 0.11 | 2143910.0 |
| OABI | ADDED | OMNIAB INC | COM | 68218J103 | 2,330,634 | 0.11 | 947412.0 |
| CAPR | UNCHANGED | CAPRICOR THERAPEUTICS INC | COM NEW | 14070B309 | 2,181,479 | 0.1 | 90593.0 |
| DRUG | REDUCED | BRIGHT MINDS BIOSCIENCES INC | COM NEW | 10919W405 | 2,127,060 | 0.1 | 30300.0 |
| ORKA | UNCHANGED | ORUKA THERAPEUTICS INC | COM | 687604108 | 1,983,343 | 0.09 | 20840.0 |
| - | VYNE THERAPEUTICS INC | COM | 92941V308 | 1,919,565 | 0.09 | 2950000.0 | |
| MCK | ADDED | MCKESSON CORP | COM | 58155Q103 | 1,889,000 | 0.09 | 2500.0 |
| LXRX | UNCHANGED | LEXICON PHARMACEUTICALS INC | COM NEW | 528872302 | 1,800,000 | 0.08 | 750000.0 |
| CRVS | ADDED | CORVUS PHARMACEUTICALS INC | COM | 221015100 | 1,749,489 | 0.08 | 117101.0 |
| CUE | NEW | CUE BIOPHARMA INC | COM | 22978P205 | 1,741,891 | 0.08 | 55193.0 |
| MSLE | UNCHANGED | SATELLOS BIOSCIENCE INC | COM | 80401L803 | 1,731,478 | 0.08 | 222555.0 |
| KNSA | UNCHANGED | KINIKSA PHARMACEUTICALS INTL | ORD SHS CL A | G52694109 | 1,721,086 | 0.08 | 26913.0 |
| - | CONNECT BIOPHARMA HLDGS LTD | SHS | G23549101 | 1,666,000 | 0.08 | 700000.0 | |
| - | COHEN CIRCLE ACQUISIT CORP I | UNIT 07/01/2030 | G2254C105 | 1,576,500 | 0.07 | 150000.0 | |
| RCKT | ADDED | ROCKET PHARMACEUTICALS INC | COM | 77313F106 | 1,489,410 | 0.07 | 435500.0 |
| TRAX | NEW | FIRST TRACKS BIOTHERAPEUTICS | ORD SHS | 337185102 | 1,446,829 | 0.07 | 71910.0 |
| EVMN | REDUCED | EVOMMUNE INC | COM SHS | 30054Y107 | 1,382,625 | 0.06 | 104035.0 |
| CCCC | ADDED | C4 THERAPEUTICS INC | COM STK | 12529R107 | 1,363,439 | 0.06 | 291957.0 |
| BCRX | ADDED | BIOCRYST PHARMACEUTICALS INC | COM | 09058V103 | 1,330,000 | 0.06 | 133000.0 |
| SUPN | REDUCED | SUPERNUS PHARMACEUTICALS | COM | 868459108 | 1,294,931 | 0.06 | 27842.0 |
| NVO | REDUCED | NOVO-NORDISK A S | ADR | 670100205 | 1,294,380 | 0.06 | 27000.0 |
| AVTR | ADDED | AVANTOR INC | COM | 05352A100 | 1,287,000 | 0.06 | 130000.0 |
| INM | NEW | INMED PHARMACEUTICALS INC | COM NEW | 457637700 | 1,240,000 | 0.06 | 800000.0 |
| PMN | REDUCED | PROMIS NEUROSCIENCES INC | COM SHS | 74346M505 | 1,221,906 | 0.06 | 92850.0 |
| - | ARROWHEAD PHARMACEUTICALS IN | NOTE 1/1 | 04280AAC4 | 1,190,560 | 0.05 | 10000.0 | |
| ARTV | NEW | ARTIVA BIOTHERAPEUTICS INC | COM | 04317A107 | 1,150,653 | 0.05 | 118624.0 |
| TNYA | ADDED | TENAYA THERAPEUTICS INC | COM | 87990A106 | 1,149,670 | 0.05 | 1555500.0 |
| - | ALX ONCOLOGY HLDGS INC | COM | 00166B105 | 1,104,676 | 0.05 | 533660.0 | |
| - | ALEXANDRIA REAL ESTATE EQ IN | COM | 015271109 | 1,030,575 | 0.05 | 19500.0 | |
| RNAC | NEW | CARTESIAN THERAPEUTICS INC | COM NEW | 816212302 | 1,030,298 | 0.05 | 98877.0 |
| - | CYCLERION THERAPEUTICS INC | COM | 23255M204 | 1,012,786 | 0.05 | 298757.0 | |
| - | ELECTRONIC ARTS INC | COM | 285512109 | 1,012,077 | 0.05 | 4936.0 | |
| TVTX | NEW | TRAVERE THERAPEUTICS INC | NOTE 0.500% 5/1 | 89422GAB3 | 1,000,000 | 0.05 | 10000.0 |
| BNTX | ADDED | BIONTECH SE | SPONSORED ADS | 09075V102 | 986,330 | 0.05 | 10600.0 |
| ACAD | NEW | ACADIA PHARMACEUTICALS INC | COM | 004225108 | 985,562 | 0.05 | 38955.0 |
| DYN | REDUCED | DYNE THERAPEUTICS INC | COM | 26818M108 | 951,054 | 0.04 | 42821.0 |
| MPLT | REDUCED | MAPLIGHT THERAPEUTICS INC | COM | 56565P103 | 949,652 | 0.04 | 26497.0 |
| GPCR | NEW | STRUCTURE THERAPEUTICS INC | SPONSORED ADS | 86366E106 | 939,225 | 0.04 | 17500.0 |
| KVACF | UNCHANGED | KEEN VISION ACQUISITION CORP | SHS | G52443119 | 930,000 | 0.04 | 75000.0 |
| WVE | ADDED | WAVE LIFE SCIENCES LTD | SHS | Y95308105 | 929,600 | 0.04 | 160000.0 |
| AURA | NEW | AURA BIOSCIENCES INC | COM | 05153U107 | 924,079 | 0.04 | 130152.0 |
| - | CHURCHILL CAP CORP XI | CL A ORD SHS | G2131A108 | 872,500 | 0.04 | 50000.0 | |
| KZIA | NEW | KAZIA THERAPEUTICS LTD | SPONSORED ADS | 48669G303 | 866,624 | 0.04 | 61550.0 |
| - | NUVALENT INC | COM | 670703107 | 857,337 | 0.04 | 6942.0 | |
| LRMR | ADDED | LARIMAR THERAPEUTICS INC | COM | 517125100 | 831,872 | 0.04 | 272745.0 |
| VERA | ADDED | VERA THERAPEUTICS INC | CL A | 92337R101 | 786,197 | 0.04 | 18322.0 |
| - | ADAGIO MED HLDGS INC | COM | 00534B100 | 785,469 | 0.04 | 1205447.0 | |
| RNA | UNCHANGED | ATRIUM THERAPEUTICS INC | COM | 04965N104 | 775,904 | 0.04 | 57688.0 |
| TXMD | ADDED | THERAPEUTICSMD INC | COM NEW | 88338N206 | 756,808 | 0.03 | 342447.0 |
| IDYA | UNCHANGED | IDEAYA BIOSCIENCES INC | COM | 45166A102 | 745,400 | 0.03 | 20000.0 |
| SIBN | ADDED | SI BONE INC | COM | 825704109 | 734,400 | 0.03 | 45000.0 |
| AMLX | REDUCED | AMYLYX PHARMACEUTICALS INC | COM | 03237H101 | 720,196 | 0.03 | 40100.0 |
| RPRX | ADDED | ROYALTY PHARMA PLC | SHS CLASS A | G7709Q104 | 700,875 | 0.03 | 12500.0 |
| EOLS | ADDED | EVOLUS INC | COM | 30052C107 | 694,000 | 0.03 | 100000.0 |
| - | ULTRAGENYX PHARMACEUTICAL IN | COM | 90400D108 | 667,800 | 0.03 | 20000.0 | |
| IBIO | REDUCED | IBIO INC | COM NEW | 451033708 | 657,179 | 0.03 | 375531.0 |
| FWRD | REDUCED | FORWARD AIR CORP | COM | 34986A104 | 651,736 | 0.03 | 48241.0 |
| GERN | ADDED | GERON CORP | COM | 374163103 | 647,446 | 0.03 | 505817.0 |
| SYK | NEW | STRYKER CORPORATION | COM | 863667101 | 629,680 | 0.03 | 2000.0 |
| NVO | REDUCED | NOVO-NORDISK A S | ADR | 670100205 | 623,220 | 0.03 | 13000.0 |
| IOVA | NEW | IOVANCE BIOTHERAPEUTICS INC | COM | 462260100 | 607,734 | 0.03 | 146090.0 |
| MGNX | ADDED | MACROGENICS INC | COM | 556099109 | 599,778 | 0.03 | 129822.0 |
| GILD | REDUCED | GILEAD SCIENCES INC | COM | 375558103 | 587,228 | 0.03 | 4648.0 |
| NTRA | UNCHANGED | NATERA INC | COM | 632307104 | 582,803 | 0.03 | 2147.0 |
| SPTX | NEW | SEAPORT THERAPEUTICS INC | COMMON STOCK | 81221K108 | 564,720 | 0.03 | 26000.0 |
| - | CORBUS PHARMACEUTICALS HLDGS | COM NEW | 21833P301 | 562,800 | 0.03 | 60000.0 | |
| ASMB | ADDED | ASSEMBLY BIOSCIENCES INC | COM NEW | 045396207 | 561,884 | 0.03 | 20447.0 |
| HELP | ADDED | CYBIN INC | COM NEW | 23256X407 | 537,248 | 0.02 | 81278.0 |
| BNTC | ADDED | BENITEC BIOPHARMA INC | COM NEW | 08205P209 | 535,200 | 0.02 | 40000.0 |
| PYPD | UNCHANGED | POLYPID LTD | COM | M8001Q126 | 528,066 | 0.02 | 103950.0 |
| LUNG | ADDED | PULMONX CORP | COM | 745848101 | 525,846 | 0.02 | 404497.0 |
| MLTX | REDUCED | MOONLAKE IMMUNOTHERAPEUTICS | CLASS A ORD | 61559X104 | 525,690 | 0.02 | 27000.0 |
| - | GLOBA TERRA ACQUISITION COR | UNIT 99/99/9999 | G3933N108 | 519,500 | 0.02 | 50000.0 | |
| TRAW | ADDED | TRAWS PHARMA INC | COM NEW | 68232V884 | 504,065 | 0.02 | 597729.0 |
| - | WISDOMTREE TR | FLOATNG RAT TREA | 97717Y527 | 503,500 | 0.02 | 10000.0 | |
| TECX | ADDED | TECTONIC THERAPEUTIC INC | COM | 878972108 | 498,472 | 0.02 | 14501.0 |
| MDGL | UNCHANGED | MADRIGAL PHARMACEUTICALS INC | COM | 558868105 | 480,570 | 0.02 | 895.0 |
| ARVN | UNCHANGED | ARVINAS INC | COM | 04335A105 | 478,581 | 0.02 | 57591.0 |
| KIDS | ADDED | ORTHOPEDIATRICS CORP | COM | 68752L100 | 478,250 | 0.02 | 25000.0 |
| COGT | NEW | COGENT BIOSCIENCES INC | COM | 19240Q201 | 472,140 | 0.02 | 12200.0 |
| PHAT | UNCHANGED | PHATHOM PHARMACEUTICALS INC | COM | 71722W107 | 465,465 | 0.02 | 42900.0 |
| MIRM | REDUCED | MIRUM PHARMACEUTICALS INC | COM | 604749101 | 456,573 | 0.02 | 3900.0 |
| KPRX | UNCHANGED | KIORA PHARMACEUTICALS INC | COM | 49721T507 | 441,685 | 0.02 | 167941.0 |
| KURA | UNCHANGED | KURA ONCOLOGY INC | COM | 50127T109 | 438,800 | 0.02 | 40000.0 |
| CNTX | ADDED | CONTEXT THERAPEUTICS INC | COM | 21077P108 | 415,962 | 0.02 | 750969.0 |
| - | ISHARES TR | 0-5 YR TIPS ETF | 46429B747 | 408,640 | 0.02 | 4000.0 | |
| KLRS | UNCHANGED | KALARIS THERAPEUTICS INC | COM | 482929106 | 407,000 | 0.02 | 100000.0 |
| BCAX | UNCHANGED | BICARA THERAPEUTICS INC | COM | 055477103 | 406,901 | 0.02 | 13705.0 |
| MRK | UNCHANGED | MERCK & CO INC | COM | 58933Y105 | 403,490 | 0.02 | 3140.0 |
| NMRA | ADDED | NEUMORA THERAPEUTICS INC. | COM | 640979100 | 357,000 | 0.02 | 210000.0 |
| IRTC | NEW | IRHYTHM HOLDINGS INC | COM | 450056106 | 356,850 | 0.02 | 3000.0 |
| - | ACHIEVE LIFE SCIENCE INC | COM | 004468500 | 351,314 | 0.02 | 53800.0 | |
| - | ALIBABA GROUP HLDG LTD | SPONSORED ADS | 01609W102 | 343,416 | 0.02 | 3578.0 | |
| WW | REDUCED | WW INTL INC | COM NEW | 98262P200 | 340,374 | 0.02 | 21300.0 |
| CNSP | NEW | CNS PHARMACEUTICALS INC | COM | 18978H508 | 334,600 | 0.02 | 70000.0 |
| CBIO | REDUCED | CRESCENT BIOPHARMA INC. | COM | G2545C104 | 328,950 | 0.02 | 18275.0 |
| BSX | REDUCED | BOSTON SCIENTIFIC CORP | COM | 101137107 | 320,100 | 0.01 | 7500.0 |
| ALT | NEW | ALTIMMUNE INC | COM NEW | 02155H200 | 312,582 | 0.01 | 102823.0 |
| VSTM | ADDED | VERASTEM INC | COM NEW | 92337C203 | 289,556 | 0.01 | 75800.0 |
| ANTX | ADDED | AN2 THERAPEUTICS INC | COM | 037326105 | 284,631 | 0.01 | 58808.0 |
| - | JOURNEY MED CORP | COM | 48115J109 | 279,780 | 0.01 | 39517.0 | |
| PCAP | UNCHANGED | PROCAP ACQUISITION CORP | UNIT 05/16/2030 | G7257A113 | 279,368 | 0.01 | 26940.0 |
| PMVP | REDUCED | PMV PHARMACEUTICALS INC | COM | 69353Y103 | 269,351 | 0.01 | 201008.0 |
| CMPX | REDUCED | COMPASS THERAPEUTICS INC | COM | 20454B104 | 267,469 | 0.01 | 122132.0 |
| JD | UNCHANGED | JD.COM INC | SPON ADS CL A | 47215P106 | 254,800 | 0.01 | 10000.0 |
| RZLT | REDUCED | REZOLUTE INC | COM NEW | 76200L309 | 253,131 | 0.01 | 48679.0 |
| ANAB | UNCHANGED | ANAPTYSBIO INC | COM | 032724106 | 249,615 | 0.01 | 3698.0 |
| NGNE | NEW | NEUROGENE INC | COM | 64135M105 | 245,310 | 0.01 | 7800.0 |
| - | ISHARES TR | U.S. MED DVC ETF | 464288810 | 242,109 | 0.01 | 4900.0 | |
| RXST | ADDED | RXSIGHT INC | COM | 78349D107 | 241,000 | 0.01 | 50000.0 |
| COYA | UNCHANGED | COYA THERAPEUTICS INC | COMMON STOCK | 22407B108 | 239,265 | 0.01 | 40900.0 |
| BCYC | REDUCED | BICYCLE THERAPEUTICS PLC | SPONSORED ADS | 088786108 | 214,705 | 0.01 | 50638.0 |
| - | CANTOR EQUITY PARTNERS VI IN | CL A ORD SHS | G1828R101 | 207,400 | 0.01 | 20000.0 | |
| SCYX | NEW | SCYNEXIS INC | COM | 811292309 | 201,005 | 0.01 | 49387.0 |
| PSNL | REDUCED | PERSONALIS INC | COM | 71535D106 | 201,000 | 0.01 | 15000.0 |
| QCLS | UNCHANGED | Q/C TECHNOLOGIES INC | COM | 62856X300 | 195,000 | 0.01 | 50000.0 |
| CABA | NEW | CABALETTA BIO INC | COM | 12674W109 | 155,500 | 0.01 | 50000.0 |
| - | RECURSION PHARMACEUTICALS IN | CL A | 75629V104 | 150,470 | 0.01 | 41000.0 | |
| OGN | UNCHANGED | ORGANON & CO | COMMON STOCK | 68622V106 | 135,400 | 0.01 | 10000.0 |
| - | MILESTONE PHARMACEUTICALS IN | COM | 59935V107 | 134,000 | 0.01 | 100000.0 | |
| NEUP | UNCHANGED | NEUPHORIA THERAPEUTICS INC | COM | 64136E102 | 131,100 | 0.01 | 30000.0 |
| STIM | UNCHANGED | NEURONETICS INC | COM | 64131A105 | 130,000 | 0.01 | 100000.0 |
| CMMB | UNCHANGED | CHEMOMAB THERAPEUTICS LTD | SPONSORED ADS | 16385C203 | 129,600 | 0.01 | 80000.0 |
| STI | UNCHANGED | SOLIDION TECHNOLOGY INC | COM NEW | 834212201 | 125,415 | 0.01 | 13500.0 |
| VYGR | UNCHANGED | VOYAGER THERAPEUTICS INC | COM | 92915B106 | 122,500 | 0.01 | 35000.0 |
| TRDA | REDUCED | ENTRADA THERAPEUTICS INC | COM | 29384C108 | 114,080 | 0.01 | 15500.0 |
| VERU | UNCHANGED | VERU INC | COM NEW | 92536C202 | 109,550 | 0.01 | 35000.0 |
| - | CANTOR EQUITY PARTNERS VII I | CL A ORD SHS | G1828W100 | 100,900 | 0.0 | 10000.0 | |
| CLNN | NEW | CLENE INC | COM NEW | 185634201 | 92,325 | 0.0 | 15000.0 |
| VTGN | REDUCED | VISTAGEN THERAPEUTICS INC | COM | 92840H400 | 79,358 | 0.0 | 351141.0 |
| LGVN | REDUCED | LONGEVERON INC | CL A NEW | 54303L203 | 76,209 | 0.0 | 108406.0 |
| BMEA | UNCHANGED | BIOMEA FUSION INC | COM | 09077A106 | 63,827 | 0.0 | 43420.0 |
| LITS | UNCHANGED | LITE STRATEGY INC | COM | 55279B301 | 62,070 | 0.0 | 67292.0 |
| JSPR | UNCHANGED | JASPER THERAPEUTICS INC | COM NEW | 471871202 | 58,940 | 0.0 | 140000.0 |
| ARDX | REDUCED | ARDELYX INC | COM | 039697107 | 56,100 | 0.0 | 11000.0 |
| GOSS | REDUCED | GOSSAMER BIO INC | COM | 38341P102 | 34,983 | 0.0 | 212531.0 |
| ATYR | UNCHANGED | ATYR PHARMA INC | COM NEW | 002120202 | 30,249 | 0.0 | 50685.0 |
| - | A SPAC III ACQUISITION CORP | RIGHT 01/02/2026 | G0544A145 | 19,114 | 0.0 | 215000.0 | |
| - | PROQR THRAPEUTICS N V | SHS EURO | N71542109 | 18,600 | 0.0 | 10000.0 | |
| BSAA | UNCHANGED | BEST SPAC I ACQUISITION CORP | RIGHT 05/27/2030 | G1069P129 | 16,560 | 0.0 | 100000.0 |
| CHRS | UNCHANGED | COHERUS ONCOLOGY INC | COM | 19249H103 | 14,512 | 0.0 | 10366.0 |
Quarterly portfolios
| Period | Filed | Value ($) | Positions | Vol % | Beta | Max DD % |
|---|---|---|---|---|---|---|
| 2026-06-30 | 2026-08-14 | 2,185,183,006 | 277 | 8.529435 | 0.145584 | 22.196086 |
| 2026-03-31 | 2026-05-18 | 1,698,675,488 | 311 | 8.552126 | 0.132448 | 21.056484 |
| 2025-12-31 | 2026-02-18 | 1,361,602,179 | 270 | 8.262676 | 0.125338 | 20.433259 |
| 2025-09-30 | 2025-11-14 | 1,064,573,342 | 220 | 7.93836 | 0.124309 | 20.830943 |
| 2025-03-31 | 2025-05-15 | 538,666,337 | 202 | 8.829753 | 0.148409 | 15.666474 |
| 2024-12-31 | 2025-02-13 | 500,371,182 | 214 | 10.149447 | 0.172555 | 17.497224 |