← All institutions

Institutional Holdings

XNCR

Ownership Summary

Institutions Holding
261
Total Shares Held
95,165,849
Total Value Held
$1,428,944,957
Quarter
2025-12-31

Active Positions

Increased Positions
16
6,386,118 shares
Decreased Positions
15
1,269,576 shares
Held Positions
7
99,350 shares
New Positions
211
87,410,805 shares
Sold Out Positions
12
155,966 shares
Institution Shares Value Change % of Portfolio Reported
BlackRock, Inc. 11,927,218 $182,605,708 New position 2025-12-31
PRIMECAP MANAGEMENT CO/CA/ 10,218,322 $156,442,509 New position 2025-12-31
BVF INC/IL 7,133,720 $109,217,253 New position 2025-12-31
RTW INVESTMENTS, LP 6,777,461 $103,762,928 New position 2025-12-31
RA CAPITAL MANAGEMENT, L.P. 5,274,274 $84,915,811 ▲ +377,037 0.74% 2026-06-30
STATE STREET CORP 4,507,254 $69,006,059 New position 2025-12-31
VANGUARD CAPITAL MANAGEMENT LLC 3,278,802 $52,788,712 New position 0.00% 2026-06-30
TCG Crossover Management, LLC 2,452,138 $37,542,233 New position 2025-12-31
VANGUARD PORTFOLIO MANAGEMENT LLC 2,215,690 $35,672,609 New position 0.00% 2026-06-30
GEODE CAPITAL MANAGEMENT, LLC 1,752,918 $26,842,201 New position 2025-12-31
MORGAN STANLEY 1,508,727 $23,098,626 New position 2025-12-31
UBS Group AG 638,021 $9,768,101 New position 2025-12-31
BAKER BROS. ADVISORS LP 1,102,106 $16,873,243 New position 2025-12-31
Legal & General Group Plc 1,308,088 $20,026,828 New position 2025-12-31
DIMENSIONAL FUND ADVISORS LP 1,249,288 $19,125,117 New position 2025-12-31
GOLDMAN SACHS GROUP INC 753,258 $11,532,380 New position 2025-12-31
MILLENNIUM MANAGEMENT LLC 594,435 $9,100,800 New position 2025-12-31
TWO SIGMA INVESTMENTS, LP 268,737 $4,114,363 New position 2025-12-31
NORTHERN TRUST CORP 674,657 $10,328,998 New position 2025-12-31
JOHNSON & JOHNSON 748,062 $11,452,829 New position 2025-12-31
Jefferies Financial Group Inc. 720,440 $11,029,936 New position 2025-12-31
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 700,435 $10,723,660 New position 2025-12-31
PANAGORA ASSET MANAGEMENT INC 583,778 $8,937,641 New position 2025-12-31
Deep Track Capital, LP 593,551 $9,556,171 New position 0.14% 2026-06-30
TORONTO DOMINION BANK 491,000 $7,517,210 New position 2025-12-31
VANGUARD FIDUCIARY TRUST CO 487,084 $7,842,052 New position 0.00% 2026-06-30
Seven Fleet Capital Management LP 368,305 $7,828,524 ▲ +288,305 1.29% 2026-06-30
AQR CAPITAL MANAGEMENT LLC 112,271 $1,718,869 New position 2025-12-31
Bank of New York Mellon Corp 410,650 $6,287,051 New position 2025-12-31
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 119,789 $1,833,969 New position 2025-12-31
BANK OF AMERICA CORP /DE/ 629,408 $9,636,237 ▼ -124,421 2025-12-31
PRINCIPAL FINANCIAL GROUP INC 340,326 $5,210,391 New position 2025-12-31
Invesco Ltd. 265,820 $4,069,705 New position 2025-12-31
Velan Capital Investment Management LP 255,000 $4,105,500 ▲ +5,000 2.50% 2026-06-30
PUBLIC SECTOR PENSION INVESTMENT BOARD 247,242 $3,785,275 New position 2025-12-31
ADAR1 Capital Management, LLC 112,330 $1,719,772 New position 2025-12-31
Hudson Bay Capital Management LP 425,000 $6,506,750 ▼ -495,006 2025-12-31
BARCLAYS PLC 359,235 $5,499,890 New position 2025-12-31
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. 200,000 $3,062,000 New position 2025-12-31
CITADEL ADVISORS LLC 321,808 $4,926,881 New position 2025-12-31
RHUMBLINE ADVISERS 165,797 $2,538,330 New position 2025-12-31
AMERICAN CENTURY COMPANIES INC 174,603 $2,673,172 New position 2025-12-31
CITIGROUP INC 112,275 $1,718,930 New position 2025-12-31
JPMORGAN CHASE & CO 303,979 $4,653,918 New position 2025-12-31
Susquehanna Portfolio Strategies, LLC 191,463 $2,931,299 New position 2025-12-31
KORNITZER CAPITAL MANAGEMENT INC /KS 151,410 $2,437,701 New position 0.05% 2026-06-30
Trexquant Investment LP 175,152 $2,681,577 New position 2025-12-31
Nuveen, LLC 134,051 $2,052,321 New position 2025-12-31
Jump Financial, LLC 33,198 $508,261 New position 2025-12-31
HSBC HOLDINGS PLC 125,482 $2,083,001 ▲ +66,903 0.00% 2026-06-30
AMERIPRISE FINANCIAL INC 135,806 $2,079,190 New position 2025-12-31
DEUTSCHE BANK AG TAUNUSANLAGE 12 D-60325 119,822 $1,929,134 ▼ -103,847 0.00% 2026-06-30
FMR LLC 92,883 $1,422,047 New position 2025-12-31
OP Asset Management Ltd 110,055 $1,771,886 New position 0.02% 2026-06-30
XTX Topco Ltd 32,009 $490,058 New position 2025-12-31
WINTON GROUP Ltd 88,038 $1,347,862 New position 2025-12-31
DCF Advisers, LLC 154,736 $2,369,008 New position 2025-12-31
Essex LLC 98,661 $1,588,442 Unchanged 0.24% 2026-06-30
Swiss National Bank 119,600 $1,831,076 New position 2025-12-31
Quinn Opportunity Partners LLC 30,000 $459,300 New position 2025-12-31
Erste Asset Management GmbH 480,200 $7,347,354 New position 2025-12-31
VOLORIDGE INVESTMENT MANAGEMENT, LLC 87,717 $1,342,947 New position 2025-12-31
RAYMOND JAMES FINANCIAL INC 38,037 $582,347 New position 2025-12-31
PRUDENTIAL FINANCIAL INC 67,570 $1,034,497 New position 2025-12-31
ALPS ADVISORS INC 58,639 $897,763 New position 2025-12-31
ALLIANCEBERNSTEIN L.P. 72,090 $1,103,698 New position 2025-12-31
Point72 Asset Management, L.P. 55,339 $847,240 New position 2025-12-31
BNP PARIBAS FINANCIAL MARKETS 48,687 $745,398 New position 2025-12-31
TD ASSET MANAGEMENT INC 77,802 $1,191,149 New position 2025-12-31
WELLS FARGO & COMPANY/MN 79,667 $1,219,702 New position 2025-12-31
Man Group plc 19,096 $292,360 New position 2025-12-31
Rafferty Asset Management, LLC 97,749 $1,496,537 New position 2025-12-31
Quantinno Capital Management LP 47,134 $721,622 New position 2025-12-31
D. E. Shaw & Co., Inc. 50,475 $812,648 New position 0.00% 2026-06-30
MANUFACTURERS LIFE INSURANCE COMPANY, THE 82,942 $1,252,541 New position 2025-12-31
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 58,530 $896,094 New position 2025-12-31
Russell Investments Group, Ltd. 47,189 $722,477 New position 2025-12-31
SUSQUEHANNA INTERNATIONAL GROUP, LLP 30,803 $471,594 New position 2025-12-31
FRANKLIN RESOURCES INC 41,225 $631,154 New position 2025-12-31
Inspire Investing, LLC 30,676 $469,652 New position 2025-12-31
MetLife Investment Management, LLC 40,212 $615,646 New position 2025-12-31
Cerity Partners LLC 31,302 $479,233 New position 2025-12-31
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 38,448 $587,042 New position 2025-12-31
Palumbo Wealth Management LLC 37,540 $604,394 ▲ +19,734 0.13% 2026-06-30
EntryPoint Capital, LLC 32,752 $527,307 ▲ +7,460 0.13% 2026-06-30
Louisiana State Employees Retirement System 32,500 $523,250 ▲ +800 0.01% 2026-06-30
VANGUARD ASSET MANAGEMENT, Ltd 31,393 $505,427 New position 0.00% 2026-06-30
LPL Financial LLC 21,474 $328,767 New position 2025-12-31
PROFUND ADVISORS LLC 43,960 $673,028 New position 2025-12-31
State of Tennessee, Department of Treasury 28,276 $341,857 New position 2025-12-31
Squarepoint Ops LLC 28,507 $458,963 New position 0.00% 2026-06-30
Vanguard Global Advisers, LLC 27,626 $444,779 New position 0.00% 2026-06-30
Zurcher Kantonalbank (Zurich Cantonalbank) 20,480 $313,549 New position 2025-12-31
HighVista Strategies LLC 26,822 $431,834 ▼ -26,223 0.10% 2026-06-30
Virtus Investment Advisers, LLC 16,103 $246,537 New position 2025-12-31
Creative Planning 17,791 $272,380 New position 2025-12-31
NEW YORK STATE COMMON RETIREMENT FUND 18,989 $290,722 New position 2025-12-31
Jupiter Topco LLC 23,986 $386,295 New position 0.00% 2026-06-30
BANK OF MONTREAL /CAN/ 21,887 $335,090 New position 2025-12-31
DIVERSIFIED TRUST CO 22,490 $362,089 ▲ +962 0.01% 2026-06-30
Mitsubishi UFJ Asset Management Co., Ltd. 15,387 $229,574 New position 2025-12-31
Rockefeller Capital Management L.P. 15,545 $237,994 New position 2025-12-31
Police & Firemen's Retirement System of New Jersey 17,627 $269,869 New position 2025-12-31
CIBC Bancorp USA Inc. 13,895 $304,211 ▼ -24,743 0.00% 2026-06-30
Lynx1 Capital Management LP 705,558 $10,802,093 New position 2025-12-31
Brevan Howard Capital Management LP 23,051 $352,911 New position 2025-12-31
Mariner, LLC 17,681 $284,609 New position 0.00% 2026-06-30
IEQ CAPITAL, LLC 17,642 $284,036 New position 0.00% 2026-06-30
YOUSIF CAPITAL MANAGEMENT, LLC 17,422 $280,494 ▲ +146 0.00% 2026-06-30
MERCER GLOBAL ADVISORS INC /ADV 17,151 $276,132 New position 0.00% 2026-06-30
STATE OF WISCONSIN INVESTMENT BOARD 38,825 $594,411 New position 2025-12-31
OREGON PUBLIC EMPLOYEES RETIREMENT FUND 16,312 $249,737 New position 2025-12-31
FIFTH THIRD BANCORP 449 $6,874 New position 2025-12-31
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 16,579 $253,824 New position 2025-12-31
AXQ CAPITAL, LP 16,215 $261,062 New position 0.03% 2026-06-30
INTECH INVESTMENT MANAGEMENT LLC 70,612 $1,081,070 New position 2025-12-31
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 28,147 $251,647 ▲ +9,688 0.00% 2026-06-30
Vanguard Investments Australia, Ltd. 14,865 $239,327 New position 0.00% 2026-06-30
State of New Jersey Common Pension Fund D 14,821 $238,618 ▼ -2,263 0.00% 2026-06-30
VOYA INVESTMENT MANAGEMENT LLC 12,923 $197,851 New position 2025-12-31
EP Wealth Advisors, LLC 13,188 $201,908 New position 2025-12-31
LOS ANGELES CAPITAL MANAGEMENT LLC 34,097 $481,790 New position 2025-12-31
KLP KAPITALFORVALTNING AS 12,900 $197,499 New position 2025-12-31
Arizona State Retirement System 17,160 $262,720 New position 2025-12-31
Aigen Investment Management, LP 12,418 $199,930 New position 0.05% 2026-06-30
ProShare Advisors LLC 16,853 $258,019 New position 2025-12-31
NorthCrest Asset Manangement, LLC 12,068 $194,476 ▲ +1,247 0.00% 2026-06-30
China Universal Asset Management Co., Ltd. 11,636 $178,147 New position 2025-12-31
Y-Intercept (Hong Kong) Ltd 11,023 $177,470 New position 0.00% 2026-06-30
VICTORY CAPITAL MANAGEMENT INC 10,658 $163,174 New position 2025-12-31
Maryland State Retirement & Pension System 10,370 $158,765 New position 2025-12-31
Pictet Asset Management Holding SA 10,740 $164,429 New position 2025-12-31
ALLSTATE CORP 10,505 $169,131 New position 0.00% 2026-06-30
Jain Global LLC 10,038 $161,612 New position 0.00% 2026-06-30
Arax Advisory Partners 70 $1,072 New position 2025-12-31
Ensign Peak Advisors, Inc 5,577 $85,384 New position 2025-12-31
NISA INVESTMENT ADVISORS, LLC 6,951 $111,911 ▼ -102 0.00% 2026-06-30
Ameritas Investment Partners, Inc. 5,885 $90,099 New position 2025-12-31
PNC FINANCIAL SERVICES GROUP, INC. 5,573 $85,323 New position 2025-12-31
ROYAL BANK OF CANADA 5,233 $79,000 New position 2025-12-31
Pinnacle Wealth Planning Services, Inc. 4,238 $64,884 New position 2025-12-31
GAMMA Investing LLC 3,697 $59,522 ▼ -146 0.00% 2026-06-30
Versant Capital Management, Inc 3,440 $55,384 ▼ -216 0.00% 2026-06-30
Allworth Financial LP 2,576 $39,439 New position 2025-12-31
Mirae Asset Global Investments Co., Ltd. 6,940 $106,252 New position 2025-12-31
Tower Research Capital LLC (TRC) 2,075 $31,768 New position 2025-12-31
US BANCORP DE U.S. BANCORP 2,432 $39,155 ▲ +1,827 0.00% 2026-06-30
PRICE T ROWE ASSOCIATES INC /MD/ 1,601,762 $24,524 New position 2025-12-31
Integrated Wealth Concepts LLC 1,837 $29,574 New position 0.00% 2026-06-30
GF FUND MANAGEMENT CO. LTD. 1,402 $21,465 New position 2025-12-31
Sterling Capital Management LLC 4,060 $62,159 New position 2025-12-31
Nykredit A/S 1,323 $21,300 New position 0.00% 2026-06-30
Amova Asset Management Americas, Inc. 1,182 $19,030 New position 0.00% 2026-06-30
State of Wyoming 1,089 $17,533 New position 0.00% 2026-06-30
Farther Finance Advisors, LLC 998 $15,698 ▼ -198 0.00% 2026-06-30
Salomon & Ludwin, LLC 587 $8,376 New position 2025-12-31
SUMMIT SECURITIES GROUP LLC 568 $9,145 New position 0.00% 2026-06-30
UMB Bank, n.a. 524 $8,022 New position 2025-12-31
EverSource Wealth Advisors, LLC 155 $2,373 New position 2025-12-31
GHP Investment Advisors, Inc. 468 $7,166 New position 2025-12-31
Smartleaf Asset Management LLC 41 $616 New position 2025-12-31
SIMPLEX TRADING, LLC 6,460 $98,902 New position 2025-12-31
ROTHSCHILD INVESTMENT LLC 85 $1,301 New position 2025-12-31
HUNTINGTON NATIONAL BANK 322 $4,930 New position 2025-12-31
HighMark Wealth Management LLC 300 $4,593 New position 2025-12-31
Boreal Capital Management LLC 250 $3,828 Unchanged 2025-12-31
Blue Trust, Inc. 222 $3,574 Unchanged 0.00% 2026-06-30
Private Wealth Management Group, LLC 141 $2,271 Unchanged 0.00% 2026-06-30
True Wealth Design, LLC 129 $2,077 ▲ +55 0.00% 2026-06-30
SJS Investment Consulting Inc. 116 $1,868 New position 0.00% 2026-06-30
MassMutual Private Wealth & Trust, FSB 115 $1,852 ▼ -204 0.00% 2026-06-30
Quarry LP 111 $1,787 New position 0.00% 2026-06-30
Essential Partners LLC 110 $1,771 ▼ -99 0.00% 2026-06-30
OSAIC HOLDINGS, INC. 116 $1,776 New position 2025-12-31
Cedar Mountain Advisors, LLC 88 $1,347 New position 2025-12-31
HRT FINANCIAL LP 74,615 $1,201 ▲ +14,908 0.00% 2026-06-30
Keating Financial Advisory Services, Inc. 74 $1,191 ▼ -8 0.00% 2026-06-30
NEW YORK STATE TEACHERS RETIREMENT SYSTEM 70,526 $1,080 New position 2025-12-31
SG Americas Securities, LLC 68,168 $1,098 ▲ +602 0.00% 2026-06-30
ACADIAN ASSET MANAGEMENT LLC 411,725 $6,302 New position 2025-12-31
THRIVENT FINANCIAL FOR LUTHERANS 82,828 $1,268 New position 2025-12-31
Clearstead Advisors, LLC 58 $935 New position 0.00% 2026-06-30
CANADA LIFE ASSURANCE Co 57,164 $875 New position 2025-12-31
SIGNATUREFD, LLC 55 $886 Unchanged 0.00% 2026-06-30
FARMERS & MERCHANTS INVESTMENTS INC 46 $704 New position 2025-12-31
Caitong International Asset Management Co., Ltd 37 $596 New position 0.00% 2026-06-30
GSA CAPITAL PARTNERS LLP 14,099 $216 New position 2025-12-31
Ankerstar Wealth, LLC 34 $521 New position 2025-12-31
State of Alaska, Department of Revenue 24,417 $393 ▼ -10,833 0.00% 2026-06-30
NATIXIS ADVISORS, LLC 17,532 $268 New position 2025-12-31
ASSETMARK, INC 20 $322 Unchanged 0.00% 2026-06-30
AMALGAMATED BANK 20,694 $317 New position 2025-12-31
Plante Moran Financial Advisors, LLC 18 $290 New position 0.00% 2026-06-30
IFP Advisors, Inc 6 $92 ▼ -12 2025-12-31
TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY 17,496 $268 New position 2025-12-31
JFS WEALTH ADVISORS, LLC 16 $258 New position 0.00% 2026-06-30
GILPIN WEALTH MANAGEMENT, LLC 8 $123 New position 2025-12-31
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO 9,276 $142 New position 2025-12-31
JPL Wealth Management, LLC 7 $113 New position 0.00% 2026-06-30
Silver Grove Financial Group, Inc. 7 $113 New position 0.00% 2026-06-30
Davis Capital Management 4 $64 New position 0.00% 2026-06-30
HANTZ FINANCIAL SERVICES, INC. 3,857 $59 New position 2025-12-31
Wealth Enhancement Trust Services, Inc. 2 $32 New position 0.00% 2026-06-30
BESSEMER GROUP INC 417 $6 New position 2025-12-31
Global Retirement Partners, LLC 1 $16 New position 0.00% 2026-06-30
Hughes Financial Services, LLC 1 $16 Unchanged 0.00% 2026-06-30
Pacer Advisors, Inc. 901 $15 New position 0.00% 2026-06-30
Covestor Ltd 6 $0 New position 2025-12-31
EcoR1 Capital, LLC 3,318,612 $50,807,950 New position 2025-12-31
JACOBS LEVY EQUITY MANAGEMENT, INC 259,319 $3,970,174 New position 2025-12-31
Nantahala Capital Management, LLC 164,639 $2,520,623 New position 2025-12-31
ALGERT GLOBAL LLC 124,400 $1,905 New position 2025-12-31
DRW Securities, LLC 0 $0 Sold out 2026-06-30
Campbell & CO Investment Adviser LLC 0 $0 Sold out 2026-06-30
Linden Thomas Advisory Services, LLC 0 $0 Sold out 2026-06-30
Qube Research & Technologies Ltd 0 $0 Sold out 2026-06-30
RENAISSANCE TECHNOLOGIES LLC 34,158 $522,959 New position 2025-12-31
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS 17,679 $270,665 New position 2025-12-31
Sanctuary Advisors, LLC 15,896 $243,368 New position 2025-12-31
Centiva Capital, LP 12,299 $188,298 New position 2025-12-31
FEDERATED HERMES, INC. 1,548 $23,700 New position 2025-12-31
BNP Paribas Asset Management Holding S.A. 690 $11 New position 2025-12-31
Quantbot Technologies LP 0 $0 Sold out 2026-06-30
QUADRANT CAPITAL GROUP LLC 638 $9,768 New position 2025-12-31
GROUP ONE TRADING LLC 1,200 $18,372 New position 2025-12-31
TWIN PEAKS WEALTH ADVISORS, LLC 0 $0 Sold out 2026-06-30
Sound Income Strategies, LLC 0 $0 Sold out 2026-06-30
MAI Capital Management 0 $0 Sold out 2026-06-30
Advisory Services Network, LLC 0 $0 Sold out 2026-06-30
Wealth Preservation Advisors, LLC 0 $0 Sold out 2026-06-30
Abound Wealth Management 0 $0 Sold out 2026-06-30
Freestone Grove Partners LP 0 $0 Sold out 2026-06-30
VANGUARD GROUP INC 7,165,450 $109,703,040 New position 2025-12-31
Defilade Capital Management, L.P. 1,414,755 $21,659,899 New position 2025-12-31
TWO SIGMA ADVISERS, LP 506,600 $7,756,046 New position 2025-12-31
BRAIDWELL LP 459,166 $7,029,831 New position 2025-12-31
DEUTSCHE BANK AG\ 216,568 $3,315,656 New position 2025-12-31
Woodline Partners LP 193,117 $2,956,621 New position 2025-12-31
Rhenman & Partners Asset Management AB 165,750 $2,537,633 New position 2025-12-31
NEOS Investment Management LLC 61,362 $939,452 New position 2025-12-31
Schonfeld Strategic Advisors LLC 47,848 $732,552 New position 2025-12-31
CIBC Private Wealth Group LLC 40,017 $612,660 New position 2025-12-31
TUDOR INVESTMENT CORP ET AL 34,794 $532,696 ▲ +1,497 2025-12-31
WELLINGTON MANAGEMENT GROUP LLP 29,031 $444,465 New position 2025-12-31
Brooklyn Investment Group 29,142 $442,085 New position 2025-12-31
JANUS HENDERSON GROUP PLC 23,986 $367,106 New position 2025-12-31
AlphaQuest LLC 21,192 $324,450 New position 2025-12-31
FOX RUN MANAGEMENT, L.L.C. 19,708 $301,729 New position 2025-12-31
JANE STREET GROUP, LLC 19,306 $295,575 New position 2025-12-31
TWINBEECH CAPITAL LP 17,200 $263,332 New position 2025-12-31
COMERICA BANK 17,015 $260,499 New position 2025-12-31
Engineers Gate Manager LP 12,713 $194,636 New position 2025-12-31
Entropy Technologies, LP 11,966 $183,199 New position 2025-12-31
NORGES BANK 11,457 $175,407 New position 2025-12-31
American Wealth Advisors, LLC 1,480 $22,658 New position 2025-12-31
US BANCORP \DE\ 819 $12,539 New position 2025-12-31
Parkside Financial Bank & Trust 57 $873 New position 2025-12-31
DekaBank Deutsche Girozentrale 31,800 $775 New position 2025-12-31
CWM, LLC 14,752 $226 New position 2025-12-31
Dunhill Financial, LLC 1 $8 New position 2025-12-31
Daiwa Securities Group Inc. 222 $3 New position 2025-12-31