DIADEMA PARTNERS LP
CIK 0002026172
Annualised vol
13.643165%
Beta
0.326638
HHI
224.781197
Top-10 weight
37.343933%
VaR 95%
1.207411%
VaR 99%
2.032175%
Max drawdown
24.887759%
Matched value
75.157175%
Returns of reported holdings
Loading returns…
Position changes vs prior quarter
What the latest 13F shows bought and sold against the quarter before, by share count.
| Ticker | Change | Shares now | Shares before | Share change % | Value now ($) |
|---|---|---|---|---|---|
| VKTX | ADDED | 2,013,108 | 1,184,381 | 69.97% | 78,531,343 |
| BMY | NEW | 930,600 | - | - | 53,621,172 |
| RVMD | REDUCED | 139,218 | 206,372 | -32.54% | 26,072,747 |
| NVS | NEW | 150,000 | - | - | 23,508,000 |
| KOD | ADDED | 561,717 | 440,062 | 27.64% | 21,884,494 |
| CAPR | REDUCED | 863,700 | 1,031,551 | -16.27% | 20,797,896 |
| COGT | ADDED | 493,664 | 322,764 | 52.95% | 19,104,797 |
| BBIO | REDUCED | 250,000 | 335,311 | -25.44% | 18,620,000 |
| CORT | ADDED | 206,300 | 168,500 | 22.43% | 17,937,785 |
| BMRN | ADDED | 312,846 | 148,229 | 111.06% | 17,901,048 |
| KYMR | NEW | 149,700 | - | - | 17,166,099 |
| SMMT | NEW | 1,120,200 | - | - | 16,321,314 |
| HIMS | NEW | 393,700 | - | - | 13,649,579 |
| REPL | ADDED | 1,198,800 | 766,060 | 56.49% | 13,270,716 |
| BIIB | NEW | 60,000 | - | - | 12,963,600 |
| LLY | ADDED | 10,000 | 6,000 | 66.67% | 11,994,300 |
| INCY | REDUCED | 105,400 | 183,429 | -42.54% | 11,948,144 |
| EWTX | ADDED | 272,214 | 212,500 | 28.1% | 11,060,055 |
| RCUS | ADDED | 347,810 | 238,142 | 46.05% | 10,722,982 |
| BNTX | NEW | 100,000 | - | - | 9,305,000 |
| PCVX | ADDED | 147,071 | 78,171 | 88.14% | 8,549,237 |
| BIOA | ADDED | 346,434 | 60,000 | 477.39% | 8,491,097 |
| NVO | ADDED | 155,900 | 70,477 | 121.21% | 7,489,288 |
| MRNA | REDUCED | 100,000 | 159,400 | -37.26% | 7,003,000 |
| CRVS | ADDED | 428,211 | 351,111 | 21.96% | 6,397,472 |
| GLUE | ADDED | 248,491 | 187,307 | 32.67% | 6,013,482 |
| ALMS | ADDED | 200,000 | 131,200 | 52.44% | 5,628,000 |
| RPRX | NEW | 100,000 | - | - | 5,607,000 |
| JNJ | REDUCED | 22,000 | 53,771 | -59.09% | 5,587,340 |
| UNCY | ADDED | 1,096,276 | 106,083 | 933.41% | 5,141,534 |
| CLDX | NEW | 136,900 | - | - | 5,094,049 |
| BHVN | UNCHANGED | 317,000 | 317,000 | 0.0% | 4,716,960 |
| VERA | NEW | 107,608 | - | - | 4,617,459 |
| TENX | ADDED | 307,000 | 179,738 | 70.8% | 4,466,850 |
| RLAY | NEW | 230,677 | - | - | 4,315,967 |
| TGTX | REDUCED | 75,700 | 206,928 | -63.42% | 4,158,958 |
| AMGN | NEW | 112,701 | - | - | 3,835,845 |
| ZYME | UNCHANGED | 142,132 | 142,132 | 0.0% | 3,715,330 |
| TSHA | NEW | 522,619 | - | - | 3,559,035 |
| NTLA | UNCHANGED | 200,000 | 200,000 | 0.0% | 3,384,000 |
| NRIX | NEW | 121,539 | - | - | 2,948,536 |
| INDV | REDUCED | 67,512 | 71,376 | -5.41% | 2,770,017 |
| ORKA | NEW | 27,799 | - | - | 2,645,631 |
| CYTK | REDUCED | 30,000 | 250,000 | -88.0% | 2,555,700 |
| RLMD | ADDED | 361,367 | 200,842 | 79.93% | 2,500,660 |
| ANNX | REDUCED | 380,716 | 486,116 | -21.68% | 2,173,888 |
| CELC | REDUCED | 20,000 | 23,014 | -13.1% | 2,092,400 |
| SEPN | ADDED | 59,700 | 202 | 29454.46% | 1,999,353 |
| HELP | NEW | 300,000 | - | - | 1,983,000 |
| VYGR | REDUCED | 563,642 | 573,642 | -1.74% | 1,972,747 |
| CTNM | NEW | 119,733 | - | - | 1,962,424 |
| BCYC | REDUCED | 462,724 | 476,424 | -2.88% | 1,961,950 |
| MGNX | REDUCED | 374,403 | 600,000 | -37.6% | 1,729,742 |
| ADMA | NEW | 200,000 | - | - | 1,674,000 |
| SPRB | ADDED | 30,000 | 10,000 | 200.0% | 1,620,000 |
| ARDX | NEW | 303,025 | - | - | 1,545,428 |
| CUE | REDUCED | 48,375 | 131,997 | -63.35% | 1,526,532 |
| MLYS | ADDED | 56,347 | 26,347 | 113.86% | 1,520,242 |
| EYPT | REDUCED | 106,300 | 284,845 | -62.68% | 1,520,090 |
| PHAT | ADDED | 129,950 | 54,650 | 137.79% | 1,409,958 |
| EOLS | ADDED | 200,000 | 125,200 | 59.74% | 1,388,000 |
| SYRE | NEW | 15,000 | - | - | 1,331,700 |
| CRMD | UNCHANGED | 167,500 | 167,500 | 0.0% | 1,314,875 |
| EDIT | NEW | 400,000 | - | - | 1,296,000 |
| EQ | REDUCED | 400,282 | 433,844 | -7.74% | 1,280,902 |
| PYXS | NEW | 388,200 | - | - | 1,168,482 |
| XERS | UNCHANGED | 132,746 | 132,746 | 0.0% | 1,051,348 |
| PHVS | UNCHANGED | 29,321 | 29,321 | 0.0% | 1,013,920 |
| RNAC | NEW | 87,057 | - | - | 907,134 |
| AQST | NEW | 214,600 | - | - | 892,736 |
| RIGL | NEW | 22,816 | - | - | 892,562 |
| ELTX | NEW | 212,100 | - | - | 829,311 |
| PGEN | ADDED | 135,293 | 55,293 | 144.68% | 771,170 |
| DFTX | NEW | 15,451 | - | - | 726,815 |
| PTHS | UNCHANGED | 24,773 | 24,773 | 0.0% | 700,085 |
| PEPG | ADDED | 373,284 | 150,925 | 147.33% | 671,911 |
| CGON | NEW | 7,300 | - | - | 518,665 |
| ELVN | ADDED | 10,000 | 245 | 3981.63% | 507,500 |
| LRMR | REDUCED | 146,637 | 166,637 | -12.0% | 447,243 |
| CLRB | NEW | 138,341 | - | - | 384,588 |
| FHTX | REDUCED | 66,908 | 79,944 | -16.31% | 326,511 |
| AYTU | REDUCED | 148,546 | 353,077 | -57.93% | 319,374 |
| OCGN | REDUCED | 200,000 | 500,000 | -60.0% | 306,000 |
| INO | REDUCED | 275,200 | 637,865 | -56.86% | 302,720 |
| URGN | REDUCED | 7,137 | 23,155 | -69.18% | 262,642 |
| TLPH | UNCHANGED | 153,563 | 153,563 | 0.0% | 158,170 |
| MNPR | UNCHANGED | 1,630 | 1,630 | 0.0% | 150,922 |
| UPB | REDUCED | 19,093 | 21,609 | -11.64% | 132,124 |
| JATT | NEW | 9,021 | - | - | 102,479 |
| KLRA | NEW | 3,621 | - | - | 79,771 |
| MNKD | REDUCED | 16,003 | 186,603 | -91.42% | 68,173 |
| ENTX | UNCHANGED | 23,260 | 23,260 | 0.0% | 41,170 |
| SPRY | NEW | 4,860 | - | - | 38,929 |
| APRE | NEW | 44,907 | - | - | 36,029 |
| TVRD | NEW | 16,607 | - | - | 31,553 |
| VTGN | REDUCED | 57,700 | 105,428 | -45.27% | 13,040 |
| NXTC | NEW | 7,742 | - | - | 12,387 |
| ATYR | REDUCED | 12,500 | 24,700 | -49.39% | 7,460 |
| JBIO | UNCHANGED | 1,046 | 1,046 | 0.0% | 3,174 |
| ERAS | NEW | 100 | - | - | 1,832 |
| LQDA | CLOSED OUT | 0 | 712,100 | -100.0% | 0 |
| AVXL | CLOSED OUT | 0 | 477,600 | -100.0% | 0 |
| ROIV | CLOSED OUT | 0 | 335,800 | -100.0% | 0 |
| CTMX | CLOSED OUT | 0 | 316,000 | -100.0% | 0 |
| IOVA | CLOSED OUT | 0 | 302,900 | -100.0% | 0 |
| STTK | CLOSED OUT | 0 | 293,664 | -100.0% | 0 |
| CLYM | CLOSED OUT | 0 | 286,126 | -100.0% | 0 |
| KPTI | CLOSED OUT | 0 | 241,300 | -100.0% | 0 |
| GPCR | CLOSED OUT | 0 | 199,734 | -100.0% | 0 |
| CRSP | CLOSED OUT | 0 | 106,300 | -100.0% | 0 |
| IBRX | CLOSED OUT | 0 | 106,300 | -100.0% | 0 |
| MRK | CLOSED OUT | 0 | 100,000 | -100.0% | 0 |
| VIR | CLOSED OUT | 0 | 88,800 | -100.0% | 0 |
| OLMA | CLOSED OUT | 0 | 84,000 | -100.0% | 0 |
| ENTA | CLOSED OUT | 0 | 64,952 | -100.0% | 0 |
| JAZZ | CLOSED OUT | 0 | 54,755 | -100.0% | 0 |
| ALKS | CLOSED OUT | 0 | 50,000 | -100.0% | 0 |
| LPCN | CLOSED OUT | 0 | 50,000 | -100.0% | 0 |
| EPRX | CLOSED OUT | 0 | 40,000 | -100.0% | 0 |
| CMPS | CLOSED OUT | 0 | 31,885 | -100.0% | 0 |
| JANX | CLOSED OUT | 0 | 31,600 | -100.0% | 0 |
| RCKT | CLOSED OUT | 0 | 30,579 | -100.0% | 0 |
| GHRS | CLOSED OUT | 0 | 26,836 | -100.0% | 0 |
| TARS | CLOSED OUT | 0 | 25,942 | -100.0% | 0 |
| ABBV | CLOSED OUT | 0 | 24,058 | -100.0% | 0 |
| TRVI | CLOSED OUT | 0 | 21,663 | -100.0% | 0 |
| PASG | CLOSED OUT | 0 | 19,530 | -100.0% | 0 |
| MAZE | CLOSED OUT | 0 | 15,000 | -100.0% | 0 |
| PTCHF | CLOSED OUT | 0 | 7,924 | -100.0% | 0 |
| LYEL | CLOSED OUT | 0 | 4,100 | -100.0% | 0 |
| RNA | CLOSED OUT | 0 | 2,512 | -100.0% | 0 |
Holdings (latest quarter)
| Ticker | Change | Issuer | Class | CUSIP | Value ($) | Weight % | Shares |
|---|---|---|---|---|---|---|---|
| VKTX | ADDED | VIKING THERAPEUTICS INC | COM | 92686J106 | 47,623,408 | 6.02 | 1220800.0 |
| - | ABIVAX SA | SPONSORED ADS | 00370M103 | 46,534,392 | 5.88 | 349200.0 | |
| BMY | NEW | BRISTOL-MYERS SQUIBB CO | COM | 110122108 | 34,572,000 | 4.37 | 600000.0 |
| - | ABIVAX SA | SPONSORED ADS | 00370M103 | 33,634,824 | 4.25 | 252400.0 | |
| - | UNITED THERAPEUTICS CORP DEL | COM | 91307C102 | 28,711,030 | 3.63 | 52989.0 | |
| RVMD | REDUCED | REVOLUTION MEDICINES INC | COM | 76155X100 | 26,072,747 | 3.29 | 139218.0 |
| - | ABIVAX SA | SPONSORED ADS | 00370M103 | 21,598,038 | 2.73 | 163644.0 | |
| COGT | ADDED | COGENT BIOSCIENCES INC | COM | 19240Q201 | 19,104,797 | 2.41 | 493664.0 |
| BMY | NEW | BRISTOL-MYERS SQUIBB CO | COM | 110122108 | 19,049,172 | 2.41 | 330600.0 |
| BBIO | REDUCED | BRIDGEBIO PHARMA INC | NOTE 1.750% 3/0 | 10806XAJ1 | 18,620,000 | 2.35 | 250000.0 |
| CORT | ADDED | CORCEPT THERAPEUTICS INC | COM | 218352102 | 17,937,785 | 2.27 | 206300.0 |
| BMRN | ADDED | BIOMARIN PHARMACEUTICAL INC | COM | 09061G101 | 17,901,048 | 2.26 | 312846.0 |
| VKTX | ADDED | VIKING THERAPEUTICS INC | COM | 92686J106 | 17,234,930 | 2.18 | 441808.0 |
| KYMR | NEW | KYMERA THERAPEUTICS INC | COM | 501575104 | 17,166,099 | 2.17 | 149700.0 |
| NVS | NEW | NOVARTIS AG | SPONSORED ADR | 66987V109 | 15,672,000 | 1.98 | 100000.0 |
| - | UNIQURE NV | SHS | N90064101 | 13,771,940 | 1.74 | 299000.0 | |
| VKTX | ADDED | VIKING THERAPEUTICS INC | COM | 92686J106 | 13,673,005 | 1.73 | 350500.0 |
| BIIB | NEW | BIOGEN INC | COM | 09062X103 | 12,963,600 | 1.64 | 60000.0 |
| CAPR | REDUCED | CAPRICOR THERAPEUTICS INC | COM NEW | 14070B309 | 12,868,352 | 1.63 | 534400.0 |
| SMMT | NEW | SUMMIT THERAPEUTICS INC | COM | 86627T108 | 12,533,114 | 1.58 | 860200.0 |
| LLY | ADDED | ELI LILLY & CO | COM | 532457108 | 11,994,300 | 1.52 | 10000.0 |
| INCY | REDUCED | INCYTE CORP | COM | 45337C102 | 11,948,144 | 1.51 | 105400.0 |
| EWTX | ADDED | EDGEWISE THERAPEUTICS INC | COM | 28036F105 | 11,060,055 | 1.4 | 272214.0 |
| - | UNIQURE NV | SHS | N90064101 | 10,842,524 | 1.37 | 235400.0 | |
| BNTX | NEW | BIONTECH SE | SPONSORED ADS | 09075V102 | 9,305,000 | 1.18 | 100000.0 |
| KOD | ADDED | KODIAK SCIENCES INC | COM | 50015M109 | 8,497,838 | 1.07 | 218117.0 |
| - | IMMUNOCORE HLDGS PLC | ADS | 45258D105 | 8,091,900 | 1.02 | 254863.0 | |
| CAPR | REDUCED | CAPRICOR THERAPEUTICS INC | COM NEW | 14070B309 | 7,929,544 | 1.0 | 329300.0 |
| NVS | NEW | NOVARTIS AG | SPONSORED ADR | 66987V109 | 7,836,000 | 0.99 | 50000.0 |
| REPL | ADDED | REPLIMUNE GROUP INC | COM | 76029N106 | 7,708,041 | 0.97 | 696300.0 |
| KOD | ADDED | KODIAK SCIENCES INC | COM | 50015M109 | 7,663,432 | 0.97 | 196700.0 |
| - | 4D MOLECULAR THERAPEUTICS IN | COM | 35104E100 | 7,595,723 | 0.96 | 571107.0 | |
| MRNA | REDUCED | MODERNA INC | COM | 60770K107 | 7,003,000 | 0.88 | 100000.0 |
| HIMS | NEW | HIMS & HERS HEALTH INC | COM CL A | 433000106 | 6,934,000 | 0.88 | 200000.0 |
| RCUS | ADDED | ARCUS BIOSCIENCES INC | COM | 03969F109 | 6,900,062 | 0.87 | 223810.0 |
| HIMS | NEW | HIMS & HERS HEALTH INC | COM CL A | 433000106 | 6,715,579 | 0.85 | 193700.0 |
| - | CORBUS PHARMACEUTICALS HLDGS | COM NEW | 21833P301 | 5,945,044 | 0.75 | 633800.0 | |
| - | SELLAS LIFE SCIENCES GROUP I | COM NEW | 81642T209 | 5,904,000 | 0.75 | 400000.0 | |
| KOD | ADDED | KODIAK SCIENCES INC | COM | 50015M109 | 5,723,224 | 0.72 | 146900.0 |
| ALMS | ADDED | ALUMIS INC | COM | 022307102 | 5,628,000 | 0.71 | 200000.0 |
| RPRX | NEW | ROYALTY PHARMA PLC | SHS CLASS A | G7709Q104 | 5,607,000 | 0.71 | 100000.0 |
| JNJ | REDUCED | JOHNSON & JOHNSON | COM | 478160104 | 5,587,340 | 0.71 | 22000.0 |
| REPL | ADDED | REPLIMUNE GROUP INC | COM | 76029N106 | 5,562,675 | 0.7 | 502500.0 |
| BIOA | ADDED | BIOAGE LABS INC | COM | 09077V100 | 4,904,451 | 0.62 | 200100.0 |
| NVO | ADDED | NOVO-NORDISK A S | ADR | 670100205 | 4,809,442 | 0.61 | 100000.0 |
| BHVN | UNCHANGED | BIOHAVEN LTD | COM | G1110E107 | 4,716,960 | 0.6 | 317000.0 |
| TENX | ADDED | TENAX THERAPEUTICS INC | COM NEW | 88032L605 | 4,466,850 | 0.56 | 307000.0 |
| CRVS | ADDED | CORVUS PHARMACEUTICALS INC | COM | 221015100 | 4,404,476 | 0.56 | 294811.0 |
| RLAY | NEW | RELAY THERAPEUTICS INC | COM | 75943R102 | 4,315,967 | 0.55 | 230677.0 |
| TGTX | REDUCED | TG THERAPEUTICS INC | COM | 88322Q108 | 4,158,958 | 0.53 | 75700.0 |
| GLUE | ADDED | MONTE ROSA THERAPEUTICS INC | COM | 61225M102 | 4,116,420 | 0.52 | 170100.0 |
| RCUS | ADDED | ARCUS BIOSCIENCES INC | COM | 03969F109 | 3,822,920 | 0.48 | 124000.0 |
| UNCY | ADDED | UNICYCIVE THERAPEUTICS INC | COM NEW | 90466Y202 | 3,717,294 | 0.47 | 792600.0 |
| ZYME | UNCHANGED | ZYMEWORKS INC | COM | 98985Y108 | 3,715,330 | 0.47 | 142132.0 |
| AMGN | NEW | AMGEN INC | COM | 031162100 | 3,621,200 | 0.46 | 10000.0 |
| BIOA | ADDED | BIOAGE LABS INC | COM | 09077V100 | 3,586,646 | 0.45 | 146334.0 |
| TSHA | NEW | TAYSHA GENE THERAPIES INC | COM SHS | 877619106 | 3,559,035 | 0.45 | 522619.0 |
| NTLA | UNCHANGED | INTELLIA THERAPEUTICS INC | COM | 45826J105 | 3,384,000 | 0.43 | 200000.0 |
| CLDX | NEW | CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 | 3,200,060 | 0.4 | 86000.0 |
| PCVX | ADDED | VAXCYTE INC | COM | 92243G108 | 3,086,703 | 0.39 | 53100.0 |
| NRIX | NEW | NURIX THERAPEUTICS INC | COM | 67080M103 | 2,948,536 | 0.37 | 121539.0 |
| SMMT | NEW | SUMMIT THERAPEUTICS INC | COM | 86627T108 | 2,914,000 | 0.37 | 200000.0 |
| PCVX | ADDED | VAXCYTE INC | COM | 92243G108 | 2,842,557 | 0.36 | 48900.0 |
| - | CORBUS PHARMACEUTICALS HLDGS | COM NEW | 21833P301 | 2,825,856 | 0.36 | 301264.0 | |
| INDV | REDUCED | INDIVIOR PHARMACEUTICALS INC | COM | 45579U109 | 2,770,017 | 0.35 | 67512.0 |
| - | INVENTIVA SA | ADS | 46124U107 | 2,725,718 | 0.34 | 740786.0 | |
| NVO | ADDED | NOVO-NORDISK A S | ADR | 670100205 | 2,679,846 | 0.34 | 55900.0 |
| ORKA | NEW | ORUKA THERAPEUTICS INC | COM | 687604108 | 2,645,631 | 0.33 | 27799.0 |
| PCVX | ADDED | VAXCYTE INC | COM | 92243G108 | 2,619,977 | 0.33 | 45071.0 |
| CYTK | REDUCED | CYTOKINETICS INC | COM NEW | 23282W605 | 2,555,700 | 0.32 | 30000.0 |
| RLMD | ADDED | RELMADA THERAPEUTICS INC | COM | 75955J402 | 2,500,660 | 0.32 | 361367.0 |
| VERA | NEW | VERA THERAPEUTICS INC | CL A | 92337R101 | 2,471,959 | 0.31 | 57608.0 |
| VERA | NEW | VERA THERAPEUTICS INC | CL A | 92337R101 | 2,145,500 | 0.27 | 50000.0 |
| CELC | REDUCED | CELCUITY INC | COM | 15102K100 | 2,092,400 | 0.26 | 20000.0 |
| ANNX | REDUCED | ANNEXON INC | COM | 03589W102 | 2,016,772 | 0.25 | 353200.0 |
| SEPN | ADDED | SEPTERNA INC | COM | 81734D104 | 1,999,353 | 0.25 | 59700.0 |
| CRVS | ADDED | CORVUS PHARMACEUTICALS INC | COM | 221015100 | 1,992,996 | 0.25 | 133400.0 |
| CTNM | NEW | CONTINEUM THERAPEUTICS INC | CL A | 21217B100 | 1,962,424 | 0.25 | 119733.0 |
| BCYC | REDUCED | BICYCLE THERAPEUTICS PLC | SPONSORED ADS | 088786108 | 1,961,950 | 0.25 | 462724.0 |
| GLUE | ADDED | MONTE ROSA THERAPEUTICS INC | COM | 61225M102 | 1,897,062 | 0.24 | 78391.0 |
| CLDX | NEW | CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 | 1,893,989 | 0.24 | 50900.0 |
| - | VIRIDIAN THERAPEUTICS INC | COM | 92790C104 | 1,837,000 | 0.23 | 100000.0 | |
| MGNX | REDUCED | MACROGENICS INC | COM | 556099109 | 1,729,742 | 0.22 | 374403.0 |
| - | PROQR THRAPEUTICS N V | SHS EURO | N71542109 | 1,722,390 | 0.22 | 926016.0 | |
| ADMA | NEW | ADMA BIOLOGICS INC | COM | 000899104 | 1,674,000 | 0.21 | 200000.0 |
| SPRB | ADDED | SPRUCE BIOSCIENCES INC | COM NEW | 85209E208 | 1,620,000 | 0.2 | 30000.0 |
| ARDX | NEW | ARDELYX INC | COM | 039697107 | 1,545,428 | 0.2 | 303025.0 |
| CUE | REDUCED | CUE BIOPHARMA INC | COM | 22978P205 | 1,526,526 | 0.19 | 48369.0 |
| MLYS | ADDED | MINERALYS THERAPEUTICS INC | COM | 603170101 | 1,520,242 | 0.19 | 56347.0 |
| EYPT | REDUCED | EYEPOINT INC | COM NEW | 30233G209 | 1,520,090 | 0.19 | 106300.0 |
| - | SELLAS LIFE SCIENCES GROUP I | COM NEW | 81642T209 | 1,476,000 | 0.19 | 100000.0 | |
| - | PROTHENA CORP PLC | SHS | G72800108 | 1,463,429 | 0.18 | 149482.0 | |
| VYGR | REDUCED | VOYAGER THERAPEUTICS INC | COM | 92915B106 | 1,447,747 | 0.18 | 413642.0 |
| UNCY | ADDED | UNICYCIVE THERAPEUTICS INC | COM NEW | 90466Y202 | 1,424,240 | 0.18 | 303676.0 |
| PHAT | ADDED | PHATHOM PHARMACEUTICALS INC | COM | 71722W107 | 1,409,958 | 0.18 | 129950.0 |
| EOLS | ADDED | EVOLUS INC | COM | 30052C107 | 1,388,000 | 0.18 | 200000.0 |
| SYRE | NEW | SPYRE THERAPEUTICS INC | COM NEW | 00773J202 | 1,331,700 | 0.17 | 15000.0 |
| HELP | NEW | CYBIN INC | COM NEW | 23256X407 | 1,322,000 | 0.17 | 200000.0 |
| CRMD | UNCHANGED | CORMEDIX INC | COM | 21900C308 | 1,314,875 | 0.17 | 167500.0 |
| EDIT | NEW | EDITAS MEDICINE INC | COM | 28106W103 | 1,296,000 | 0.16 | 400000.0 |
| EQ | REDUCED | EQUILLIUM INC | COM | 29446K106 | 1,280,902 | 0.16 | 400282.0 |
| PYXS | NEW | PYXIS ONCOLOGY INC | COMMON STOCK | 747324101 | 1,168,482 | 0.15 | 388200.0 |
| XERS | UNCHANGED | XERIS BIOPHARMA HOLDINGS INC | COM | 98422E103 | 1,051,348 | 0.13 | 132746.0 |
| PHVS | UNCHANGED | PHARVARIS N V | COM | N69605108 | 1,013,920 | 0.13 | 29321.0 |
| - | HARMONY BIOSCIENCES HLDGS IN | COM | 413197104 | 978,118 | 0.12 | 26864.0 | |
| RNAC | NEW | CARTESIAN THERAPEUTICS INC | COM NEW | 816212302 | 907,134 | 0.11 | 87057.0 |
| AQST | NEW | AQUESTIVE THERAPEUTICS INC | COM | 03843E104 | 892,736 | 0.11 | 214600.0 |
| RIGL | NEW | RIGEL PHARMACEUTICALS INC | COM | 766559702 | 892,562 | 0.11 | 22816.0 |
| SMMT | NEW | SUMMIT THERAPEUTICS INC | COM | 86627T108 | 874,200 | 0.11 | 60000.0 |
| PGEN | ADDED | PRECIGEN INC | COM | 74017N105 | 771,170 | 0.1 | 135293.0 |
| DFTX | NEW | DEFINIUM THERAPEUTICS INC | COM SHS | 24477V105 | 726,815 | 0.09 | 15451.0 |
| PTHS | UNCHANGED | PELTHOS THERAPEUTICS INC | COM SHS | 171126204 | 700,085 | 0.09 | 24773.0 |
| PEPG | ADDED | PEPGEN INC | COM | 713317105 | 671,911 | 0.08 | 373284.0 |
| HELP | NEW | CYBIN INC | COM NEW | 23256X407 | 661,000 | 0.08 | 100000.0 |
| VYGR | REDUCED | VOYAGER THERAPEUTICS INC | COM | 92915B106 | 525,000 | 0.07 | 150000.0 |
| CGON | NEW | CG ONCOLOGY INC | COM | 156944100 | 518,665 | 0.07 | 7300.0 |
| ELVN | ADDED | ENLIVEN THERAPEUTICS INC | COM | 29337E102 | 507,500 | 0.06 | 10000.0 |
| - | CONNECT BIOPHARMA HLDGS LTD | SHS | G23549101 | 468,824 | 0.06 | 196985.0 | |
| LRMR | REDUCED | LARIMAR THERAPEUTICS INC | COM | 517125100 | 447,243 | 0.06 | 146637.0 |
| ELTX | NEW | ELICIO THERAPEUTICS INC | COM | 28657F103 | 438,311 | 0.06 | 112100.0 |
| ELTX | NEW | ELICIO THERAPEUTICS INC | COM | 28657F103 | 391,000 | 0.05 | 100000.0 |
| CLRB | NEW | CELLECTAR BIOSCIENCES INC | COM NEW | 15117F880 | 384,588 | 0.05 | 138341.0 |
| FHTX | REDUCED | FOGHORN THERAPEUTICS INC | COM | 344174107 | 326,511 | 0.04 | 66908.0 |
| AYTU | REDUCED | AYTU BIOPHARMA INC | COM | 054754858 | 319,374 | 0.04 | 148546.0 |
| OCGN | REDUCED | OCUGEN INC | COM | 67577C105 | 306,000 | 0.04 | 200000.0 |
| INO | REDUCED | INOVIO PHARMACEUTICALS INC | COM SHS | 45773H409 | 302,720 | 0.04 | 275200.0 |
| URGN | REDUCED | UROGEN PHARMA LTD | COM | M96088105 | 262,642 | 0.03 | 7137.0 |
| AMGN | NEW | AMGEN INC | COM | 031162100 | 214,645 | 0.03 | 102701.0 |
| - | HERON THERAPEUTICS INC | COM | 427746102 | 195,783 | 0.02 | 458723.0 | |
| TLPH | UNCHANGED | TALPHERA INC | COM NEW | 00444T209 | 158,170 | 0.02 | 153563.0 |
| ANNX | REDUCED | ANNEXON INC | COM | 03589W102 | 157,116 | 0.02 | 27516.0 |
| MNPR | UNCHANGED | MONOPAR THERAPEUTICS INC | COM NEW | 61023L207 | 150,922 | 0.02 | 1630.0 |
| - | LAKELAND INDS INC | COM | 511795106 | 150,815 | 0.02 | 14108.0 | |
| UPB | REDUCED | UPSTREAM BIO INC | COM | 91678A107 | 132,124 | 0.02 | 19093.0 |
| - | MEIRAGTX HLDGS PLC | COM | G59665102 | 113,052 | 0.01 | 8368.0 | |
| JATT | NEW | JATT II ACQUISITION CORP | ORD SHS | G50765109 | 102,479 | 0.01 | 9021.0 |
| KLRA | NEW | KAILERA THERAPEUTICS INC | COMMON STOCK | 482931102 | 79,771 | 0.01 | 3621.0 |
| MNKD | REDUCED | MANNKIND CORP | COM NEW | 56400P706 | 68,173 | 0.01 | 16003.0 |
| ENTX | UNCHANGED | ENTERA BIO LTD | SHS | M40527109 | 41,170 | 0.01 | 23260.0 |
| SPRY | NEW | ARS PHARMACEUTICALS INC | COM | 82835W108 | 38,929 | 0.0 | 4860.0 |
| APRE | NEW | APREA THERAPEUTICS INC | COM NEW | 03836J201 | 36,029 | 0.0 | 44907.0 |
| TVRD | NEW | TVARDI THERAPEUTICS INC | COM | 140755307 | 31,553 | 0.0 | 16607.0 |
| VTGN | REDUCED | VISTAGEN THERAPEUTICS INC | COM | 92840H400 | 13,040 | 0.0 | 57700.0 |
| NXTC | NEW | NEXTCURE INC | COM NEW | 65343E207 | 12,387 | 0.0 | 7742.0 |
| ATYR | REDUCED | ATYR PHARMA INC | COM NEW | 002120202 | 7,460 | 0.0 | 12500.0 |
| - | MEIRAGTX HLDGS PLC | COM | G59665102 | 6,755 | 0.0 | 500.0 | |
| JBIO | UNCHANGED | JADE BIOSCIENCES INC | COM NEW | 008064206 | 3,174 | 0.0 | 1046.0 |
| ERAS | NEW | ERASCA INC | COM | 29479A108 | 1,832 | 0.0 | 100.0 |
| CUE | REDUCED | CUE BIOPHARMA INC | COM | 22978P205 | 6 | 0.0 | 6.0 |
Quarterly portfolios
| Period | Filed | Value ($) | Positions | Vol % | Beta | Max DD % |
|---|---|---|---|---|---|---|
| 2026-06-30 | 2026-08-14 | 791,347,834 | 149 | 13.643165 | 0.326638 | 24.887759 |
| 2026-03-31 | 2026-05-15 | 587,736,973 | 144 | 11.73799 | 0.2829 | 22.684779 |
| 2025-12-31 | 2026-02-17 | 580,539,432 | 145 | 11.249946 | 0.290838 | 20.84298 |
| 2025-09-30 | 2025-11-14 | 390,971,772 | 130 | 9.764513 | 0.278966 | 18.642738 |
| 2025-03-31 | 2025-05-15 | 383,273,722 | 102 | 12.266448 | 0.391798 | 16.256555 |
| 2024-12-31 | 2025-02-14 | 233,054,096 | 107 | 6.80242 | 0.168882 | 10.603434 |