← All institutions
Institutional Holdings
ZYMEOwnership Summary
Institutions Holding
264
Total Shares Held
78,085,039
Total Value Held
$1,987,451,711
Quarter
2025-12-31
Active Positions
Increased Positions
10
1,688,924 shares
Decreased Positions
17
1,211,347 shares
Held Positions
8
1,138,527 shares
New Positions
215
74,046,241 shares
Sold Out Positions
14
980,755 shares
| Institution | Shares | Value | Change | % of Portfolio | Reported |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC | 22,970,388 | $604,810,316 | New position | 2025-12-31 | |
| Rubric Capital Management LP | 5,750,000 | $151,397,500 | New position | 2025-12-31 | |
| BlackRock, Inc. | 4,595,548 | $121,000,779 | New position | 2025-12-31 | |
| PERCEPTIVE ADVISORS LLC | 3,261,850 | $85,884,511 | New position | 2025-12-31 | |
| BVF INC/IL | 3,938,641 | $103,704,418 | New position | 2025-12-31 | |
| MORGAN STANLEY | 2,593,080 | $68,275,801 | New position | 2025-12-31 | |
| BNP Paribas Asset Management Holding S.A. | 1,822,048 | $47,975 | New position | 2025-12-31 | |
| VANGUARD CAPITAL MANAGEMENT LLC | 1,558,998 | $40,752,208 | New position | 0.00% | 2026-06-30 |
| Assenagon Asset Management S.A. | 1,252,027 | $32,727,986 | ▲ +524,041 | 0.04% | 2026-06-30 |
| Nextech Invest Ltd. | 1,113,946 | $29,118,548 | Unchanged | 1.38% | 2026-06-30 |
| STATE STREET CORP | 1,037,642 | $27,321,114 | New position | 2025-12-31 | |
| DIMENSIONAL FUND ADVISORS LP | 1,159,215 | $30,523,404 | New position | 2025-12-31 | |
| CITADEL ADVISORS LLC | 300,251 | $7,905,609 | New position | 2025-12-31 | |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 889,802 | $23,259,000 | New position | 0.03% | 2026-06-30 |
| FMR LLC | 560,086 | $14,747,059 | New position | 2025-12-31 | |
| GEODE CAPITAL MANAGEMENT, LLC | 647,970 | $17,060,446 | New position | 2025-12-31 | |
| Prosight Management, LP | 530,393 | $13,965,248 | New position | 2025-12-31 | |
| Qube Research & Technologies Ltd | 474,290 | $12,488,056 | New position | 2025-12-31 | |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 510,032 | $13,332,236 | New position | 0.00% | 2026-06-30 |
| Redmile Group, LLC | 491,654 | $12,945,250 | New position | 2025-12-31 | |
| Capricorn Fund Managers Ltd | 486,529 | $12,717,868 | ▼ -520,681 | 1.00% | 2026-06-30 |
| GOLDMAN SACHS GROUP INC | 420,207 | $11,064,051 | New position | 2025-12-31 | |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 700,002 | $18,431,053 | New position | 2025-12-31 | |
| DEUTSCHE BANK AG TAUNUSANLAGE 12 D-60325 | 397,190 | $10,382,547 | ▼ -524,060 | 0.00% | 2026-06-30 |
| Hillsdale Investment Management Inc. | 237,922 | $6,264,487 | New position | 2025-12-31 | |
| FIRST TRUST ADVISORS LP | 340,363 | $8,897,088 | New position | 0.01% | 2026-06-30 |
| Granahan Investment Management, LLC | 224,408 | $5,908,663 | New position | 2025-12-31 | |
| NORTHERN TRUST CORP | 307,979 | $8,109,087 | New position | 2025-12-31 | |
| Pictet Asset Management Holding SA | 73,627 | $1,966,024 | New position | 2025-12-31 | |
| PICTON MAHONEY ASSET MANAGEMENT | 244,798 | $6,445,531 | New position | 2025-12-31 | |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 459,788 | $12,106,218 | New position | 2025-12-31 | |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 181,790 | $4,786,531 | New position | 2025-12-31 | |
| BANK OF AMERICA CORP /DE/ | 89,524 | $2,357,168 | ▼ -85,803 | 2025-12-31 | |
| WELLS FARGO & COMPANY/MN | 208,313 | $5,484,873 | New position | 2025-12-31 | |
| SummitTX Capital, L.P. | 224,268 | $5,904,976 | New position | 2025-12-31 | |
| Man Group plc | 75,318 | $1,983,123 | New position | 2025-12-31 | |
| FEDERATED HERMES, INC. | 152,689 | $4,020,302 | New position | 2025-12-31 | |
| RAYMOND JAMES FINANCIAL INC | 187,685 | $4,941,747 | New position | 2025-12-31 | |
| STATE OF WISCONSIN INVESTMENT BOARD | 75,566 | $1,989,653 | New position | 2025-12-31 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 220,909 | $5,816,534 | New position | 2025-12-31 | |
| KENNEDY CAPITAL MANAGEMENT LLC | 145,534 | $3,831,910 | New position | 2025-12-31 | |
| D. E. Shaw & Co., Inc. | 223,786 | $5,892,285 | New position | 2025-12-31 | |
| DIADEMA PARTNERS LP | 262,000 | $6,898,460 | New position | 2025-12-31 | |
| CITIGROUP INC | 111,207 | $2,928,080 | New position | 2025-12-31 | |
| Bank of New York Mellon Corp | 128,131 | $3,373,687 | New position | 2025-12-31 | |
| XTX Topco Ltd | 93,469 | $2,461,039 | New position | 2025-12-31 | |
| Nuveen, LLC | 648,326 | $17,070,424 | New position | 2025-12-31 | |
| PANAGORA ASSET MANAGEMENT INC | 78,336 | $2,062,587 | New position | 2025-12-31 | |
| UBS Group AG | 278,854 | $7,342,226 | New position | 2025-12-31 | |
| Invesco Ltd. | 257,580 | $6,782,081 | New position | 2025-12-31 | |
| AQR CAPITAL MANAGEMENT LLC | 91,075 | $2,398,005 | New position | 2025-12-31 | |
| WELLINGTON MANAGEMENT GROUP LLP | 181,705 | $4,784,292 | New position | 2025-12-31 | |
| Tidal Investments LLC | 105,615 | $2,760,776 | ▲ +684 | 0.00% | 2026-06-30 |
| Tema ETFs LLC | 105,615 | $2,760,776 | New position | 0.09% | 2026-06-30 |
| PLATINUM INVESTMENT MANAGEMENT LTD | 105,184 | $2,769,495 | New position | 2025-12-31 | |
| Manatuck Hill Partners, LLC | 100,000 | $2,614,000 | ▲ +60,000 | 0.87% | 2026-06-30 |
| JPMORGAN CHASE & CO | 35,008 | $921,760 | New position | 2025-12-31 | |
| KORNITZER CAPITAL MANAGEMENT INC /KS | 88,800 | $2,338,104 | New position | 2025-12-31 | |
| MACKENZIE FINANCIAL CORP | 45,460 | $1,204,135 | New position | 2025-12-31 | |
| PRINCIPAL FINANCIAL GROUP INC | 84,990 | $2,221,639 | ▲ +6,443 | 0.00% | 2026-06-30 |
| Y-Intercept (Hong Kong) Ltd | 22,643 | $596,190 | New position | 2025-12-31 | |
| LMR Partners LLP | 82,500 | $2,156,550 | New position | 0.01% | 2026-06-30 |
| AMERIPRISE FINANCIAL INC | 113,141 | $2,979,002 | New position | 2025-12-31 | |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 320,261 | $8,432,472 | New position | 2025-12-31 | |
| VANGUARD FIDUCIARY TRUST CO | 80,120 | $2,094,337 | New position | 0.00% | 2026-06-30 |
| STIFEL FINANCIAL CORP | 75,847 | $1,997,055 | New position | 2025-12-31 | |
| FRANKLIN RESOURCES INC | 58,987 | $1,553,128 | New position | 2025-12-31 | |
| Swiss National Bank | 74,200 | $1,953,686 | New position | 2025-12-31 | |
| TWO SIGMA INVESTMENTS, LP | 71,874 | $1,878,786 | New position | 0.00% | 2026-06-30 |
| Dana Investment Advisors, Inc. | 48,318 | $1,272,213 | New position | 2025-12-31 | |
| CREDIT AGRICOLE S A | 75,000 | $1,974,750 | New position | 2025-12-31 | |
| Fisher Asset Management, LLC | 68,197 | $1,795,627 | New position | 2025-12-31 | |
| SEGALL BRYANT & HAMILL, LLC | 66,836 | $1,747,093 | ▲ +21,110 | 0.02% | 2026-06-30 |
| Verdad Advisers, LP | 66,688 | $1,743,224 | ▼ -16,010 | 1.67% | 2026-06-30 |
| Susquehanna Portfolio Strategies, LLC | 99,795 | $2,627,602 | New position | 2025-12-31 | |
| Campbell & CO Investment Adviser LLC | 33,588 | $884,372 | New position | 2025-12-31 | |
| SIMPLEX TRADING, LLC | 48,040 | $1,264,893 | New position | 2025-12-31 | |
| ROYAL BANK OF CANADA | 55,055 | $1,450,000 | New position | 2025-12-31 | |
| ALLIANCEBERNSTEIN L.P. | 50,030 | $1,317,290 | New position | 2025-12-31 | |
| Virtus Investment Advisers, LLC | 10,441 | $274,912 | New position | 2025-12-31 | |
| ENVESTNET ASSET MANAGEMENT INC | 40,812 | $1,074,580 | New position | 2025-12-31 | |
| Quantinno Capital Management LP | 28,883 | $760,489 | New position | 2025-12-31 | |
| Legal & General Group Plc | 32,149 | $846,483 | New position | 2025-12-31 | |
| VICTORY CAPITAL MANAGEMENT INC | 42,905 | $1,129,688 | New position | 2025-12-31 | |
| MARSHALL WACE, LLP | 40,948 | $1,070,380 | ▲ +8,725 | 0.00% | 2026-06-30 |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC | 43,052 | $1,133,559 | New position | 2025-12-31 | |
| Russell Investments Group, Ltd. | 58,350 | $1,536,353 | New position | 2025-12-31 | |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 37,761 | $994,247 | New position | 2025-12-31 | |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 36,922 | $965,141 | ▼ -5,864 | 0.00% | 2026-06-30 |
| Persistent Asset Partners Ltd | 7,346 | $193,420 | New position | 2025-12-31 | |
| HighVista Strategies LLC | 34,013 | $889,100 | ▼ -72 | 0.20% | 2026-06-30 |
| COMMONWEALTH EQUITY SERVICES, LLC | 26,095 | $687,080 | New position | 2025-12-31 | |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 17,433 | $459,011 | New position | 2025-12-31 | |
| Creative Planning | 28,293 | $744,955 | New position | 2025-12-31 | |
| SBI Okasan Asset Management Co.Ltd. | 32,000 | $855,680 | New position | 2025-12-31 | |
| MetLife Investment Management, LLC | 28,630 | $753,828 | New position | 2025-12-31 | |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 27,670 | $723,294 | ▲ +316 | 0.00% | 2026-06-30 |
| STRS OHIO | 26,600 | $700,378 | New position | 2025-12-31 | |
| VANGUARD ASSET MANAGEMENT, Ltd | 26,279 | $686,933 | New position | 0.00% | 2026-06-30 |
| Brevan Howard Capital Management LP | 23,333 | $614,358 | New position | 2025-12-31 | |
| Jump Financial, LLC | 25,608 | $669,393 | New position | 0.01% | 2026-06-30 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 20,421 | $537,685 | New position | 2025-12-31 | |
| RITHOLTZ WEALTH MANAGEMENT | 24,243 | $633,712 | Unchanged | 0.01% | 2026-06-30 |
| BNP PARIBAS FINANCIAL MARKETS | 23,298 | $613,436 | New position | 2025-12-31 | |
| Duncan Williams Asset Management, LLC | 22,095 | $510,615 | New position | 2025-12-31 | |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 23,109 | $608,460 | New position | 2025-12-31 | |
| BARCLAYS PLC | 79,966 | $2,105,504 | New position | 2025-12-31 | |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 27,935 | $735,529 | New position | 2025-12-31 | |
| BetterWealth, LLC | 18,622 | $486,779 | New position | 0.09% | 2026-06-30 |
| BANK OF MONTREAL /CAN/ | 17,468 | $459,932 | New position | 2025-12-31 | |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 387 | $7,399 | New position | 2025-12-31 | |
| Jupiter Topco LLC | 18,200 | $475,657 | New position | 0.00% | 2026-06-30 |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 18,185 | $475,356 | New position | 0.01% | 2026-06-30 |
| JANE STREET GROUP, LLC | 70,445 | $1,854,818 | New position | 2025-12-31 | |
| NEW YORK STATE COMMON RETIREMENT FUND | 17,371 | $457,378 | New position | 2025-12-31 | |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 32,815 | $864,018 | New position | 2025-12-31 | |
| Squarepoint Ops LLC | 16,200 | $423,468 | ▼ -66,946 | 0.00% | 2026-06-30 |
| HSBC HOLDINGS PLC | 15,588 | $421,205 | ▼ -22,189 | 0.00% | 2026-06-30 |
| Vinva Investment Management Ltd | 12,216 | $483,860 | New position | 2025-12-31 | |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 15,340 | $403,902 | New position | 2025-12-31 | |
| AGF MANAGEMENT LTD | 15,000 | $394,950 | New position | 2025-12-31 | |
| Police & Firemen's Retirement System of New Jersey | 13,702 | $360,774 | New position | 2025-12-31 | |
| INTECH INVESTMENT MANAGEMENT LLC | 20,330 | $535,289 | New position | 2025-12-31 | |
| State of New Jersey Common Pension Fund D | 11,923 | $311,667 | ▼ -865 | 0.00% | 2026-06-30 |
| China Universal Asset Management Co., Ltd. | 12,195 | $321,094 | New position | 2025-12-31 | |
| JAMES INVESTMENT RESEARCH, INC. | 10,925 | $287,655 | New position | 2025-12-31 | |
| Ewing Morris & Co. Investment Partners Ltd. | 10,850 | $289,183 | New position | 2025-12-31 | |
| Arizona State Retirement System | 10,395 | $273,700 | New position | 2025-12-31 | |
| Jain Global LLC | 10,010 | $261,661 | New position | 0.00% | 2026-06-30 |
| PSP Research LLC | 20,312 | $534,815 | New position | 2025-12-31 | |
| Mitsubishi UFJ Trust & Banking Corp | 9,569 | $250,134 | New position | 0.00% | 2026-06-30 |
| VOYA INVESTMENT MANAGEMENT LLC | 9,234 | $243,131 | New position | 2025-12-31 | |
| Vanguard Investments Australia, Ltd. | 8,803 | $230,110 | New position | 0.00% | 2026-06-30 |
| Allspring Global Investments Holdings, LLC | 8,762 | $225,359 | ▲ +255 | 0.00% | 2026-06-30 |
| ProShare Advisors LLC | 12,387 | $326,151 | New position | 2025-12-31 | |
| INCEPTIONR LLC | 8,313 | $217,302 | New position | 0.05% | 2026-06-30 |
| Magnetar Financial LLC | 8,292 | $216,753 | New position | 0.00% | 2026-06-30 |
| KLP KAPITALFORVALTNING AS | 8,000 | $210,640 | New position | 2025-12-31 | |
| PRUDENTIAL FINANCIAL INC | 12,755 | $335,839 | New position | 2025-12-31 | |
| Vanguard Global Advisers, LLC | 5,459 | $142,698 | New position | 0.00% | 2026-06-30 |
| Northwest & Ethical Investments L.P. | 24,088 | $639,296 | New position | 2025-12-31 | |
| Ameritas Investment Partners, Inc. | 4,164 | $109,638 | New position | 2025-12-31 | |
| Mirae Asset Global Investments Co., Ltd. | 7,274 | $191,524 | New position | 2025-12-31 | |
| Arax Advisory Partners | 169 | $4,450 | New position | 2025-12-31 | |
| State of Wyoming | 10,875 | $286,339 | New position | 2025-12-31 | |
| Tower Research Capital LLC (TRC) | 1,353 | $35,624 | New position | 2025-12-31 | |
| Asset Management One Co., Ltd. | 1,659 | $43,366 | New position | 0.00% | 2026-06-30 |
| GF FUND MANAGEMENT CO. LTD. | 1,470 | $38,705 | New position | 2025-12-31 | |
| TD Waterhouse Canada Inc. | 311 | $8,186 | New position | 2025-12-31 | |
| Caitong International Asset Management Co., Ltd | 2,073 | $54,582 | New position | 2025-12-31 | |
| Eurizon Capital SGR S.p.A. | 1,321 | $31,865 | New position | 0.00% | 2026-06-30 |
| GAMMA Investing LLC | 1,114 | $29,120 | ▲ +17 | 0.00% | 2026-06-30 |
| Optiver Holding B.V. | 1,148 | $30,307 | New position | 2025-12-31 | |
| Steward Partners Investment Advisory, LLC | 53 | $1,395 | New position | 2025-12-31 | |
| Nykredit A/S | 966 | $25,251 | New position | 0.00% | 2026-06-30 |
| LANARK FINANCIAL, INC. | 962 | $25,146 | ▲ +339 | 0.00% | 2026-06-30 |
| PNC FINANCIAL SERVICES GROUP, INC. | 781 | $20,564 | New position | 2025-12-31 | |
| OSAIC HOLDINGS, INC. | 2,510 | $66,086 | New position | 2025-12-31 | |
| Freestone Grove Partners LP | 648 | $16,939 | ▼ -12,297 | 0.00% | 2026-06-30 |
| NATIONAL BANK OF CANADA /FI/ | 545 | $14,344 | New position | 2025-12-31 | |
| Federation des caisses Desjardins du Quebec | 570 | $15,002 | New position | 2025-12-31 | |
| GROUP ONE TRADING LLC | 8,841 | $232,784 | New position | 2025-12-31 | |
| NISA INVESTMENT ADVISORS, LLC | 481 | $12,573 | ▼ -490 | 0.00% | 2026-06-30 |
| UMB Bank, n.a. | 466 | $12,270 | New position | 2025-12-31 | |
| HUNTINGTON NATIONAL BANK | 364 | $9,584 | New position | 2025-12-31 | |
| Inspire Investing, LLC | 332 | $8,675 | New position | 0.00% | 2026-06-30 |
| Parallel Advisors, LLC | 329 | $8,663 | New position | 2025-12-31 | |
| US BANCORP DE U.S. BANCORP | 315 | $8,234 | ▼ -37 | 0.00% | 2026-06-30 |
| SBI Securities Co., Ltd. | 11 | $290 | New position | 2025-12-31 | |
| Integrated Wealth Concepts LLC | 295 | $7,710 | New position | 0.00% | 2026-06-30 |
| Quarry LP | 90 | $2,370 | New position | 2025-12-31 | |
| EverSource Wealth Advisors, LLC | 182 | $4,792 | New position | 2025-12-31 | |
| Sterling Capital Management LLC | 331 | $8,715 | New position | 2025-12-31 | |
| Fortitude Family Office, LLC | 116 | $3,032 | New position | 0.00% | 2026-06-30 |
| Allworth Financial LP | 146 | $3,845 | New position | 2025-12-31 | |
| IFP Advisors, Inc | 96 | $2,528 | Unchanged | 2025-12-31 | |
| ROTHSCHILD INVESTMENT LLC | 56 | $1,474 | New position | 2025-12-31 | |
| HighMark Wealth Management LLC | 230 | $6,055 | New position | 2025-12-31 | |
| SJS Investment Consulting Inc. | 77 | $2,013 | New position | 0.00% | 2026-06-30 |
| Kilter Group LLC | 66 | $1,738 | Unchanged | 2025-12-31 | |
| Bare Financial Services, Inc | 64 | $1,685 | New position | 2025-12-31 | |
| Rockefeller Capital Management L.P. | 61 | $1,595 | Unchanged | 0.00% | 2026-06-30 |
| True Wealth Design, LLC | 58 | $1,517 | Unchanged | 0.00% | 2026-06-30 |
| Physician Wealth Advisors, Inc. | 51 | $1,343 | New position | 2025-12-31 | |
| North Growth Management Ltd. | 45,000 | $1,183 | New position | 2025-12-31 | |
| Versant Capital Management, Inc | 45 | $1,176 | Unchanged | 0.00% | 2026-06-30 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 28,784 | $758 | New position | 2025-12-31 | |
| Farther Finance Advisors, LLC | 30 | $784 | ▼ -27 | 0.00% | 2026-06-30 |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | 25 | $658 | New position | 2025-12-31 | |
| Jackson Creek Investment Advisors LLC | 18,648 | $409 | ▼ -47 | 0.14% | 2026-06-30 |
| Essential Partners LLC | 12 | $314 | Unchanged | 0.00% | 2026-06-30 |
| Janney Montgomery Scott LLC | 11,067 | $291 | New position | 2025-12-31 | |
| Smartleaf Asset Management LLC | 12 | $318 | New position | 2025-12-31 | |
| SG Americas Securities, LLC | 6,321 | $165 | ▼ -4,108 | 0.00% | 2026-06-30 |
| Clearstead Advisors, LLC | 6 | $157 | New position | 0.00% | 2026-06-30 |
| Larson Financial Group LLC | 6 | $158 | New position | 2025-12-31 | |
| Silver Grove Financial Group, Inc. | 4 | $105 | New position | 0.00% | 2026-06-30 |
| DekaBank Deutsche Girozentrale | 3,843 | $35 | New position | 2025-12-31 | |
| Hughes Financial Services, LLC | 3 | $78 | ▼ -1 | 0.00% | 2026-06-30 |
| Covestor Ltd | 54 | $1 | New position | 2025-12-31 | |
| MPM BIOIMPACT LLC | 0 | $0 | Sold out | 2026-06-30 | |
| ROYCE & ASSOCIATES LP | 0 | $0 | Sold out | 2026-06-30 | |
| HRT FINANCIAL LP | 121,064 | $3,187 | New position | 2025-12-31 | |
| AMERICAN CENTURY COMPANIES INC | 58,832 | $1,549,047 | New position | 2025-12-31 | |
| DLD Asset Management, LP | 120,600 | $3,174,795 | New position | 2025-12-31 | |
| MILLENNIUM MANAGEMENT LLC | 381,621 | $10,048,081 | New position | 2025-12-31 | |
| Connor, Clark & Lunn Investment Management Ltd. | 0 | $0 | Sold out | 2026-06-30 | |
| Engineers Gate Manager LP | 0 | $0 | Sold out | 2026-06-30 | |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 97,907 | $2,598,452 | New position | 2025-12-31 | |
| Walleye Capital LLC | 38,167 | $1,004,937 | New position | 2025-12-31 | |
| Walleye Trading LLC | 36,252 | $954,515 | New position | 2025-12-31 | |
| Headlands Technologies LLC | 0 | $0 | Sold out | 2026-06-30 | |
| GSA CAPITAL PARTNERS LLP | 0 | $0 | Sold out | 2026-06-30 | |
| Quadrature Capital Ltd | 23,017 | $606,038 | New position | 2025-12-31 | |
| Abacus Wealth Partners, LLC | 10,222 | $269,145 | New position | 2025-12-31 | |
| LAZARD ASSET MANAGEMENT LLC | 13,776 | $362,722 | New position | 2025-12-31 | |
| Soleus Capital Management, L.P. | 100,000 | $2,633,000 | New position | 2025-12-31 | |
| WINTON GROUP Ltd | 11,180 | $294,369 | New position | 2025-12-31 | |
| Global Wealth Strategies & Associates | 0 | $0 | Sold out | 2026-06-30 | |
| Sofinnova Investments, Inc. | 0 | $0 | Sold out | 2026-06-30 | |
| SIGNATUREFD, LLC | 0 | $0 | Sold out | 2026-06-30 | |
| FIFTH THIRD BANCORP | 0 | $0 | Sold out | 2026-06-30 | |
| Aster Capital Management (DIFC) Ltd | 0 | $0 | Sold out | 2026-06-30 | |
| TWIN PEAKS WEALTH ADVISORS, LLC | 0 | $0 | Sold out | 2026-06-30 | |
| CoreCap Advisors, LLC | 0 | $0 | Sold out | 2026-06-30 | |
| Root Financial Partners, LLC | 0 | $0 | Sold out | 2026-06-30 | |
| MAI Capital Management | 5 | $132 | New position | 2025-12-31 | |
| VANGUARD GROUP INC | 2,328,727 | $61,315,382 | New position | 2025-12-31 | |
| Siren, L.L.C. | 1,680,121 | $44,237,586 | New position | 2025-12-31 | |
| DEUTSCHE BANK AG\ | 1,595,833 | $42,018,282 | New position | 2025-12-31 | |
| Nextech Invest, Ltd. | 1,113,946 | $29,330,198 | New position | 2025-12-31 | |
| Vestal Point Capital, LP | 865,000 | $22,775,450 | New position | 2025-12-31 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 663,546 | $17,471,166 | New position | 2025-12-31 | |
| Schonfeld Strategic Advisors LLC | 288,571 | $7,598,072 | New position | 2025-12-31 | |
| RENAISSANCE TECHNOLOGIES LLC | 220,877 | $5,815,691 | New position | 2025-12-31 | |
| JUPITER ASSET MANAGEMENT LTD | 125,506 | $3,304,573 | New position | 2025-12-31 | |
| Opaleye Management Inc. | 108,929 | $2,868,101 | New position | 2025-12-31 | |
| Trexquant Investment LP | 101,274 | $2,666,544 | New position | 2025-12-31 | |
| ACUTA CAPITAL PARTNERS, LLC | 80,143 | $2,110,165 | New position | 2025-12-31 | |
| NEOS Investment Management LLC | 77,115 | $2,030,438 | New position | 2025-12-31 | |
| RHUMBLINE ADVISERS | 75,498 | $1,987,851 | New position | 2025-12-31 | |
| TANG CAPITAL MANAGEMENT LLC | 34,631 | $911,834 | New position | 2025-12-31 | |
| TWO SIGMA ADVISERS, LP | 31,415 | $827,157 | New position | 2025-12-31 | |
| TUDOR INVESTMENT CORP ET AL | 30,324 | $798,431 | ▼ -44,842 | 2025-12-31 | |
| JOURNEY STRATEGIC WEALTH LLC | 29,050 | $764,886 | New position | 2025-12-31 | |
| Aquatic Capital Management LLC | 24,103 | $634,632 | New position | 2025-12-31 | |
| CreativeOne Wealth, LLC | 18,264 | $480,891 | New position | 2025-12-31 | |
| JANUS HENDERSON GROUP PLC | 18,200 | $479,115 | New position | 2025-12-31 | |
| Baader Bank Aktiengesellschaft | 10,013 | $263,511 | New position | 2025-12-31 | |
| VARCOV Co. | 9,818 | $258,508 | New position | 2025-12-31 | |
| AlphaQuest LLC | 8,313 | $218,881 | New position | 2025-12-31 | |
| Brooklyn Investment Group | 8,020 | $214,455 | New position | 2025-12-31 | |
| Cresset Asset Management, LLC | 8,120 | $213,800 | New position | 2025-12-31 | |
| NBC SECURITIES, INC. | 623 | $16,403 | New position | 2025-12-31 | |
| ALGERT GLOBAL LLC | 423,646 | $11,155 | New position | 2025-12-31 | |
| US BANCORP \DE\ | 287 | $7,557 | New position | 2025-12-31 | |
| Truvestments Capital LLC | 231 | $6,082 | New position | 2025-12-31 | |
| COMERICA BANK | 211 | $5,556 | New position | 2025-12-31 | |
| Penserra Capital Management LLC | 60,146 | $1,583 | New position | 2025-12-31 | |
| Sunbelt Securities, Inc. | 27 | $711 | New position | 2025-12-31 | |
| JONES FINANCIAL COMPANIES LLLP | 20 | $527 | New position | 2025-12-31 | |
| CWM, LLC | 13,950 | $368 | New position | 2025-12-31 | |
| AMALGAMATED BANK | 1,566 | $41 | New position | 2025-12-31 | |
| Daiwa Securities Group Inc. | 186 | $5 | New position | 2025-12-31 |