Boxer Capital Management, LLC
CIK 0002018299
Annualised vol
18.30844%
Beta
0.196663
HHI
887.810913
Top-10 weight
65.148082%
VaR 95%
1.530555%
VaR 99%
3.195125%
Max drawdown
47.49477%
Matched value
84.304726%
Returns of reported holdings
Loading returns…
Position changes vs prior quarter
What the latest 13F shows bought and sold against the quarter before, by share count.
| Ticker | Change | Shares now | Shares before | Share change % | Value now ($) |
|---|---|---|---|---|---|
| TNGX | UNCHANGED | 10,876,219 | 10,876,219 | 0.0% | 339,990,606 |
| RVMD | UNCHANGED | 500,000 | 500,000 | 0.0% | 93,640,000 |
| KOD | ADDED | 1,477,600 | 1,361,000 | 8.57% | 57,567,296 |
| KYMR | ADDED | 429,100 | 329,100 | 30.39% | 49,204,897 |
| DFTX | ADDED | 998,500 | 598,500 | 66.83% | 46,969,440 |
| REPL | ADDED | 3,983,000 | 1,175,000 | 238.98% | 44,091,810 |
| CELC | ADDED | 416,530 | 225,000 | 85.12% | 43,577,368 |
| QTTB | NEW | 3,149,310 | - | - | 40,122,209 |
| CAPR | ADDED | 1,395,156 | 590,000 | 136.47% | 33,595,356 |
| PGEN | ADDED | 5,150,000 | 3,500,000 | 47.14% | 29,355,000 |
| CORT | ADDED | 335,500 | 250,000 | 34.2% | 29,171,725 |
| PTGX | UNCHANGED | 170,000 | 170,000 | 0.0% | 20,838,600 |
| VIR | UNCHANGED | 1,866,000 | 1,866,000 | 0.0% | 19,014,540 |
| PCVX | UNCHANGED | 325,000 | 325,000 | 0.0% | 18,892,250 |
| URGN | UNCHANGED | 500,000 | 500,000 | 0.0% | 18,400,000 |
| CRVS | UNCHANGED | 1,100,000 | 1,100,000 | 0.0% | 16,434,000 |
| PTCT | UNCHANGED | 200,000 | 200,000 | 0.0% | 16,314,000 |
| AMLX | UNCHANGED | 800,000 | 800,000 | 0.0% | 14,368,000 |
| OCUL | ADDED | 1,300,000 | 350,000 | 271.43% | 12,766,000 |
| IRD | ADDED | 2,815,000 | 2,250,000 | 25.11% | 11,569,650 |
| PALI | UNCHANGED | 4,799,875 | 4,799,875 | 0.0% | 10,031,739 |
| SYRE | NEW | 100,000 | - | - | 8,878,000 |
| COGT | UNCHANGED | 225,000 | 225,000 | 0.0% | 8,707,500 |
| CYTK | UNCHANGED | 100,000 | 100,000 | 0.0% | 8,519,000 |
| RLAY | NEW | 450,000 | - | - | 8,419,500 |
| CBIO | UNCHANGED | 453,686 | 453,686 | 0.0% | 8,166,348 |
| CTNM | UNCHANGED | 494,000 | 494,000 | 0.0% | 8,096,660 |
| KZIA | NEW | 560,000 | - | - | 7,884,800 |
| STTK | NEW | 1,000,000 | - | - | 6,940,000 |
| AVTX | ADDED | 375,000 | 300,000 | 25.0% | 6,930,000 |
| RLMD | UNCHANGED | 842,106 | 842,106 | 0.0% | 5,827,374 |
| MLTX | UNCHANGED | 275,000 | 275,000 | 0.0% | 5,354,250 |
| ZURA | UNCHANGED | 900,000 | 900,000 | 0.0% | 5,310,000 |
| HELP | ADDED | 790,000 | 640,000 | 23.44% | 5,221,900 |
| ODTX | NEW | 275,000 | - | - | 5,145,250 |
| IMTX | NEW | 475,000 | - | - | 4,811,750 |
| FTH | NEW | 180,505 | - | - | 4,512,625 |
| GPCR | UNCHANGED | 75,000 | 75,000 | 0.0% | 4,025,250 |
| ORIC | ADDED | 350,000 | 176,500 | 98.3% | 3,790,500 |
| ANTX | UNCHANGED | 749,035 | 749,035 | 0.0% | 3,625,329 |
| NMRA | NEW | 2,000,000 | - | - | 3,400,000 |
| INO | ADDED | 2,844,994 | 2,370,122 | 20.04% | 3,129,493 |
| ALLO | REDUCED | 1,500,000 | 2,725,000 | -44.95% | 3,120,000 |
| SLDB | UNCHANGED | 300,000 | 300,000 | 0.0% | 2,997,000 |
| KPTI | UNCHANGED | 302,536 | 302,536 | 0.0% | 2,955,777 |
| CLNN | UNCHANGED | 477,515 | 477,515 | 0.0% | 2,939,105 |
| SRPT | UNCHANGED | 150,000 | 150,000 | 0.0% | 2,695,500 |
| MPLT | NEW | 75,000 | - | - | 2,688,000 |
| NRIX | UNCHANGED | 100,000 | 100,000 | 0.0% | 2,426,000 |
| LBRX | UNCHANGED | 70,000 | 70,000 | 0.0% | 2,271,850 |
| EDSA | NEW | 205,000 | - | - | 1,666,650 |
| IVVD | UNCHANGED | 1,500,000 | 1,500,000 | 0.0% | 1,308,600 |
| UPB | UNCHANGED | 150,000 | 150,000 | 0.0% | 1,038,000 |
| PEPG | UNCHANGED | 272,892 | 272,892 | 0.0% | 491,206 |
| RGNX | UNCHANGED | 15,000 | 15,000 | 0.0% | 179,700 |
Holdings (latest quarter)
| Ticker | Change | Issuer | Class | CUSIP | Value ($) | Weight % | Shares |
|---|---|---|---|---|---|---|---|
| TNGX | UNCHANGED | TANGO THERAPEUTICS INC | COM | 87583X109 | 339,990,606 | 25.61 | 1.0876219E7 |
| RVMD | UNCHANGED | REVOLUTION MEDICINES INC | COM | 76155X100 | 93,640,000 | 7.05 | 500000.0 |
| - | ABIVAX SA | SPONSORED ADS | 00370M103 | 80,622,300 | 6.07 | 605000.0 | |
| - | UNIQURE NV | SHS | N90064101 | 69,241,998 | 5.21 | 1503300.0 | |
| KOD | ADDED | KODIAK SCIENCES INC | COM | 50015M109 | 57,567,296 | 4.34 | 1477600.0 |
| KYMR | ADDED | KYMERA THERAPEUTICS INC | COM | 501575104 | 49,204,897 | 3.71 | 429100.0 |
| DFTX | ADDED | DEFINIUM THERAPEUTICS INC | COM SHS | 24477V105 | 46,969,440 | 3.54 | 998500.0 |
| REPL | ADDED | REPLIMUNE GROUP INC | COM | 76029N106 | 44,091,810 | 3.32 | 3983000.0 |
| CELC | ADDED | CELCUITY INC | COM | 15102K100 | 43,577,368 | 3.28 | 416530.0 |
| QTTB | NEW | Q32 BIO INC | COM | 746964105 | 40,122,209 | 3.02 | 3149310.0 |
| CAPR | ADDED | CAPRICOR THERAPEUTICS INC | COM NEW | 14070B309 | 33,595,356 | 2.53 | 1395156.0 |
| PGEN | ADDED | PRECIGEN INC | COM | 74017N105 | 29,355,000 | 2.21 | 5150000.0 |
| CORT | ADDED | CORCEPT THERAPEUTICS INC | COM | 218352102 | 29,171,725 | 2.2 | 335500.0 |
| - | Surrozen Inc. | COM NEW | 86889P208 | 26,963,591 | 2.03 | 1105683.0 | |
| PTGX | UNCHANGED | PROTAGONIST THERAPEUTICS INC | COM | 74366E102 | 20,838,600 | 1.57 | 170000.0 |
| VIR | UNCHANGED | VIR BIOTECHNOLOGY INC | COM | 92764N102 | 19,014,540 | 1.43 | 1866000.0 |
| PCVX | UNCHANGED | VAXCYTE INC | COM | 92243G108 | 18,892,250 | 1.42 | 325000.0 |
| URGN | UNCHANGED | UROGEN PHARMA LTD | COM | M96088105 | 18,400,000 | 1.39 | 500000.0 |
| CRVS | UNCHANGED | CORVUS PHARMACEUTICALS INC | COM | 221015100 | 16,434,000 | 1.24 | 1100000.0 |
| PTCT | UNCHANGED | PTC THERAPEUTICS INC | COM | 69366J200 | 16,314,000 | 1.23 | 200000.0 |
| - | PRAXIS PRECISION MEDICINES I | COM NEW | 74006W207 | 15,553,339 | 1.17 | 46457.0 | |
| AMLX | UNCHANGED | AMYLYX PHARMACEUTICALS INC | COM | 03237H101 | 14,368,000 | 1.08 | 800000.0 |
| OCUL | ADDED | OCULAR THERAPEUTIX INC | COM | 67576A100 | 12,766,000 | 0.96 | 1300000.0 |
| IRD | ADDED | OPUS GENETICS INC | COM | 67577R102 | 11,569,650 | 0.87 | 2815000.0 |
| PALI | UNCHANGED | PALISADE BIO INC | COM | 696389402 | 10,031,739 | 0.76 | 4799875.0 |
| - | APOGEE THERAPEUTICS INC | COM | 03770N101 | 9,291,100 | 0.7 | 70000.0 | |
| SYRE | NEW | SPYRE THERAPEUTICS INC | COM NEW | 00773J202 | 8,878,000 | 0.67 | 100000.0 |
| COGT | UNCHANGED | COGENT BIOSCIENCES INC | COM | 19240Q201 | 8,707,500 | 0.66 | 225000.0 |
| CYTK | UNCHANGED | CYTOKINETICS INC | COM NEW | 23282W605 | 8,519,000 | 0.64 | 100000.0 |
| RLAY | NEW | RELAY THERAPEUTICS INC | COM | 75943R102 | 8,419,500 | 0.63 | 450000.0 |
| CBIO | UNCHANGED | CRESCENT BIOPHARMA INC. | COM | 38000Q201 | 8,166,348 | 0.62 | 453686.0 |
| CTNM | UNCHANGED | CONTINEUM THERAPEUTICS INC | CL A | 21217B100 | 8,096,660 | 0.61 | 494000.0 |
| KZIA | NEW | KAZIA THERAPEUTICS LTD | SPONSORED ADS | 48669G303 | 7,884,800 | 0.59 | 560000.0 |
| STTK | NEW | SHATTUCK LABS INC | COM | 82024L103 | 6,940,000 | 0.52 | 1000000.0 |
| AVTX | ADDED | AVALO THERAPEUTICS INC | COM NEW | 05338F306 | 6,930,000 | 0.52 | 375000.0 |
| - | FORTE BIOSCIENCES INC | COM NEW | 34962G208 | 5,833,125 | 0.44 | 274500.0 | |
| RLMD | UNCHANGED | RELMADA THERAPEUTICS INC | COM | 75955J402 | 5,827,374 | 0.44 | 842106.0 |
| MLTX | UNCHANGED | MOONLAKE IMMUNOTHERAPEUTICS | CLASS A ORD | 61559X104 | 5,354,250 | 0.4 | 275000.0 |
| ZURA | UNCHANGED | ZURA BIO LTD | CLASS A ORD SHS | G9TY5A101 | 5,310,000 | 0.4 | 900000.0 |
| HELP | ADDED | CYBIN INC | COM NEW | 23256X407 | 5,221,900 | 0.39 | 790000.0 |
| ODTX | NEW | ODYSSEY THERAPEUTICS INC | COMMON STOCK | 67613T104 | 5,145,250 | 0.39 | 275000.0 |
| IMTX | NEW | IMMATICS N.V | SHS | N44445109 | 4,811,750 | 0.36 | 475000.0 |
| FTH | NEW | FAETH THERAPEUTICS inc | COM NEW | 81728A207 | 4,512,625 | 0.34 | 180505.0 |
| GPCR | UNCHANGED | STRUCTURE THERAPEUTICS INC | SPONSORED ADS | 86366E106 | 4,025,250 | 0.3 | 75000.0 |
| ORIC | ADDED | ORIC PHARMACEUTICALS INC | COM | 68622P109 | 3,790,500 | 0.29 | 350000.0 |
| ANTX | UNCHANGED | AN2 THERAPEUTICS INC | COM | 037326105 | 3,625,329 | 0.27 | 749035.0 |
| NMRA | NEW | NEUMORA THERAPEUTICS INC. | COM | 640979100 | 3,400,000 | 0.26 | 2000000.0 |
| INO | ADDED | INOVIO PHARMACEUTICALS INC | COM SHS | 45773H409 | 3,129,493 | 0.24 | 2844994.0 |
| ALLO | REDUCED | ALLOGENE THERAPEUTICS INC | COM | 019770106 | 3,120,000 | 0.23 | 1500000.0 |
| SLDB | UNCHANGED | SOLID BIOSCIENCES INC | COM NEW | 83422E204 | 2,997,000 | 0.23 | 300000.0 |
| KPTI | UNCHANGED | KARYOPHARM THERAPEUTICS INC | COM NEW | 48576U205 | 2,955,777 | 0.22 | 302536.0 |
| CLNN | UNCHANGED | CLENE INC | COM NEW | 185634201 | 2,939,105 | 0.22 | 477515.0 |
| SRPT | UNCHANGED | SAREPTA THERAPEUTICS INC | COM | 803607100 | 2,695,500 | 0.2 | 150000.0 |
| MPLT | NEW | MAPLIGHT THERAPEUTICS INC | COM | 56565P103 | 2,688,000 | 0.2 | 75000.0 |
| NRIX | UNCHANGED | NURIX THERAPEUTICS INC | COM | 67080M103 | 2,426,000 | 0.18 | 100000.0 |
| LBRX | UNCHANGED | LB PHARMACEUTICALS INC | COM SHS | 50180M108 | 2,271,850 | 0.17 | 70000.0 |
| EDSA | NEW | EDESA BIOTECH INC | COM NEW | 27966L306 | 1,666,650 | 0.13 | 205000.0 |
| IVVD | UNCHANGED | INVIVYD INC | COM | 00534A102 | 1,308,600 | 0.1 | 1500000.0 |
| UPB | UNCHANGED | UPSTREAM BIO INC | COM | 91678A107 | 1,038,000 | 0.08 | 150000.0 |
| - | MILESTONE PHARMACEUTICALS IN | COM | 59935V107 | 893,332 | 0.07 | 666666.0 | |
| PEPG | UNCHANGED | PEPGEN INC | COM | 713317105 | 491,206 | 0.04 | 272892.0 |
| RGNX | UNCHANGED | REGENXBIO INC | COM | 75901B107 | 179,700 | 0.01 | 15000.0 |
| - | SURROZEN INC | *W EXP 08/01/203 | 86889P117 | 1,067 | 0.0 | 66666.0 |
Quarterly portfolios
| Period | Filed | Value ($) | Positions | Vol % | Beta | Max DD % |
|---|---|---|---|---|---|---|
| 2026-06-30 | 2026-08-14 | 1,327,787,255 | 63 | 18.30844 | 0.196663 | 47.49477 |
| 2026-03-31 | 2026-05-15 | 761,653,648 | 54 | 20.356949 | 0.198647 | 52.824049 |
| 2025-12-31 | 2026-02-17 | 456,875,787 | 45 | 16.780888 | 0.176428 | 45.21504 |
| 2025-09-30 | 2026-02-17 | 313,726,904 | 34 | 17.486715 | 0.171794 | 48.671215 |
| 2025-06-30 | 2026-02-17 | 198,660,671 | 20 | 20.197291 | 0.225904 | 48.894052 |
| 2025-03-31 | 2026-02-17 | 332,470,540 | 28 | 11.694768 | 0.169551 | 25.145068 |
| 2024-12-31 | 2025-02-14 | 1,174,519,254 | 60 | 11.773205 | 0.207476 | 28.010811 |