PFM Health Sciences, LP
CIK 0001442756
Annualised vol
10.887039%
Beta
0.376143
HHI
196.24316
Top-10 weight
33.896372%
VaR 95%
1.039875%
VaR 99%
1.749461%
Max drawdown
15.034478%
Matched value
77.49756%
Returns of reported holdings
Loading returns…
Position changes vs prior quarter
What the latest 13F shows bought and sold against the quarter before, by share count.
| Ticker | Change | Shares now | Shares before | Share change % | Value now ($) |
|---|---|---|---|---|---|
| ASND | REDUCED | 233,171 | 11,679,434 | -98.0% | 62,191,369 |
| AXSM | REDUCED | 219,596 | 264,304 | -16.92% | 53,750,513 |
| LLY | REDUCED | 39,258 | 65,762 | -40.3% | 47,087,223 |
| JAZZ | REDUCED | 160,768 | 178,144 | -9.75% | 38,740,265 |
| HUM | NEW | 94,375 | - | - | 37,487,638 |
| UNH | ADDED | 88,276 | 58,038 | 52.1% | 36,690,154 |
| NBIX | REDUCED | 213,407 | 215,678 | -1.05% | 35,966,549 |
| INBX | ADDED | 308,385 | 305,431 | 0.97% | 29,219,479 |
| RVMD | ADDED | 143,222 | 140,770 | 1.74% | 26,822,616 |
| THC | REDUCED | 126,572 | 398,567 | -68.24% | 23,679,090 |
| EW | REDUCED | 250,453 | 254,510 | -1.59% | 22,655,978 |
| PEN | REDUCED | 60,221 | 139,779 | -56.92% | 19,014,781 |
| BBIO | REDUCED | 253,358 | 257,747 | -1.7% | 18,870,104 |
| SYK | ADDED | 56,637 | 21,957 | 157.95% | 17,831,593 |
| MTD | NEW | 13,344 | - | - | 17,047,093 |
| INDV | REDUCED | 401,208 | 574,666 | -30.18% | 16,461,564 |
| MRK | NEW | 127,118 | - | - | 16,334,663 |
| CYTK | NEW | 191,686 | - | - | 16,329,730 |
| MDGL | REDUCED | 29,313 | 34,146 | -14.15% | 15,739,615 |
| ORKA | REDUCED | 158,825 | 174,052 | -8.75% | 15,115,375 |
| OSCR | ADDED | 519,016 | 499,837 | 3.84% | 14,802,336 |
| TMO | ADDED | 28,496 | 14,832 | 92.13% | 14,286,755 |
| CVS | NEW | 137,457 | - | - | 14,219,927 |
| CLDX | ADDED | 342,751 | 324,957 | 5.48% | 12,753,765 |
| NVO | ADDED | 265,016 | 197,181 | 34.4% | 12,704,867 |
| DFTX | ADDED | 249,020 | 205,317 | 21.29% | 11,713,901 |
| GILD | NEW | 90,858 | - | - | 11,479,000 |
| RYTM | REDUCED | 101,550 | 136,621 | -25.67% | 11,275,097 |
| TNGX | REDUCED | 326,047 | 406,245 | -19.74% | 10,192,229 |
| TFX | NEW | 79,708 | - | - | 10,103,786 |
| COR | NEW | 35,485 | - | - | 10,041,545 |
| VKTX | REDUCED | 255,330 | 263,106 | -2.96% | 9,960,423 |
| VERA | ADDED | 224,289 | 174,867 | 28.26% | 9,624,241 |
| ROIV | ADDED | 268,008 | 207,446 | 29.19% | 9,484,803 |
| CGON | REDUCED | 128,286 | 165,925 | -22.68% | 9,114,720 |
| AMRX | REDUCED | 480,715 | 930,096 | -48.32% | 8,321,177 |
| EPRX | ADDED | 1,210,661 | 540,871 | 123.84% | 8,002,469 |
| IRTC | NEW | 65,196 | - | - | 7,755,064 |
| KOD | ADDED | 193,315 | 114,719 | 68.51% | 7,531,552 |
| ABT | REDUCED | 82,230 | 140,432 | -41.44% | 7,461,550 |
| TAK | NEW | 444,173 | - | - | 7,120,093 |
| HNGE | NEW | 82,860 | - | - | 6,877,380 |
| ARQT | NEW | 242,069 | - | - | 6,347,049 |
| ILMN | ADDED | 35,040 | 28,869 | 21.38% | 6,161,083 |
| OCS | NEW | 436,042 | - | - | 6,047,903 |
| NTRA | REDUCED | 22,077 | 60,004 | -63.21% | 5,992,802 |
| GH | NEW | 36,701 | - | - | 5,506,251 |
| CELC | NEW | 52,155 | - | - | 5,456,456 |
| BLTE | REDUCED | 34,803 | 59,432 | -41.44% | 5,359,140 |
| GPCR | REDUCED | 91,550 | 126,383 | -27.56% | 4,913,489 |
| RCUS | NEW | 152,129 | - | - | 4,690,137 |
| ELAN | NEW | 172,489 | - | - | 4,244,954 |
| ARGX | REDUCED | 4,482 | 4,535 | -1.17% | 4,158,265 |
| SYRE | NEW | 46,217 | - | - | 4,103,145 |
| MBX | REDUCED | 70,971 | 71,894 | -1.28% | 3,917,599 |
| MIRM | NEW | 31,536 | - | - | 3,691,920 |
| CGEM | REDUCED | 192,442 | 227,406 | -15.38% | 3,504,369 |
| CMPS | REDUCED | 247,589 | 1,367,099 | -81.89% | 3,503,384 |
| HCA | REDUCED | 8,295 | 17,951 | -53.79% | 3,234,138 |
| CAPR | REDUCED | 122,221 | 123,831 | -1.3% | 2,943,082 |
| DNLI | NEW | 100,966 | - | - | 2,596,846 |
| SNDX | REDUCED | 118,422 | 245,021 | -51.67% | 2,588,705 |
| AMLX | REDUCED | 143,700 | 145,275 | -1.08% | 2,580,852 |
| TARS | REDUCED | 40,579 | 80,226 | -49.42% | 2,554,042 |
| OMDA | NEW | 114,442 | - | - | 2,512,002 |
| ERAS | NEW | 134,088 | - | - | 2,456,492 |
| BCRX | NEW | 207,357 | - | - | 2,073,570 |
| OMCL | NEW | 49,040 | - | - | 2,036,141 |
| CVRX | NEW | 369,572 | - | - | 1,899,600 |
| HIMS | NEW | 49,454 | - | - | 1,714,570 |
| MLYS | REDUCED | 62,418 | 142,677 | -56.25% | 1,684,038 |
| TECX | REDUCED | 45,631 | 46,129 | -1.08% | 1,568,566 |
| RZLT | REDUCED | 127,289 | 128,726 | -1.12% | 661,903 |
| CRBU | REDUCED | 354,687 | 957,787 | -62.97% | 624,249 |
| NEO | CLOSED OUT | 0 | 1,784,552 | -100.0% | 0 |
| PSNL | CLOSED OUT | 0 | 870,097 | -100.0% | 0 |
| ALHC | CLOSED OUT | 0 | 359,826 | -100.0% | 0 |
| GKOS | CLOSED OUT | 0 | 215,685 | -100.0% | 0 |
| DXCM | CLOSED OUT | 0 | 149,734 | -100.0% | 0 |
| BLLN | CLOSED OUT | 0 | 88,069 | -100.0% | 0 |
| MDLN | CLOSED OUT | 0 | 86,777 | -100.0% | 0 |
| ICLR | CLOSED OUT | 0 | 57,500 | -100.0% | 0 |
| CAH | CLOSED OUT | 0 | 31,941 | -100.0% | 0 |
Holdings (latest quarter)
| Ticker | Change | Issuer | Class | CUSIP | Value ($) | Weight % | Shares |
|---|---|---|---|---|---|---|---|
| ASND | REDUCED | ASCENDIS PHARMA A/S | ORD SHS | K08588103 | 62,191,369 | 5.34 | 233171.0 |
| AXSM | REDUCED | AXSOME THERAPEUTICS INC. | COM | 05464T104 | 53,750,513 | 4.61 | 219596.0 |
| LLY | REDUCED | ELI LILLY & CO | COM | 532457108 | 47,087,223 | 4.04 | 39258.0 |
| JAZZ | REDUCED | JAZZ PHARMACEUTICALS PLC | SHS USD | G50871105 | 38,740,265 | 3.32 | 160768.0 |
| HUM | NEW | HUMANA INC | COM | 444859102 | 37,487,638 | 3.22 | 94375.0 |
| UNH | ADDED | UNITEDHEALTH GROUP INC | COM | 91324P102 | 36,690,154 | 3.15 | 88276.0 |
| NBIX | REDUCED | NEUROCRINE BIOSCIENCES INC | COM | 64125C109 | 35,966,549 | 3.09 | 213407.0 |
| INBX | ADDED | INHIBRX BIOSCIENCES INC | COM | 45720N103 | 29,219,479 | 2.51 | 308385.0 |
| - | UNITED THERAPEUTICS CORP DEL | COM | 91307C102 | 27,086,624 | 2.32 | 49991.0 | |
| RVMD | ADDED | REVOLUTION MEDICINES INC | COM | 76155X100 | 26,822,616 | 2.3 | 143222.0 |
| - | ICON PUB LTD CO | SHS | G4705A100 | 23,708,288 | 2.03 | 136482.0 | |
| THC | REDUCED | TENET HEALTHCARE CORP | COM NEW | 88033G407 | 23,679,090 | 2.03 | 126572.0 |
| EW | REDUCED | EDWARDS LIFESCIENCES CORP | COM | 28176E108 | 22,655,978 | 1.94 | 250453.0 |
| - | WATERS CORP | COM | 941848103 | 22,436,768 | 1.93 | 59825.0 | |
| PEN | REDUCED | PENUMBRA INC | COM | 70975L107 | 19,014,781 | 1.63 | 60221.0 |
| BBIO | REDUCED | BRIDGEBIO PHARMA INC | COM | 10806X102 | 18,870,104 | 1.62 | 253358.0 |
| SYK | ADDED | STRYKER CORPORATION | COM | 863667101 | 17,831,593 | 1.53 | 56637.0 |
| MTD | NEW | METTLER TOLEDO INTERNATIONAL | COM | 592688105 | 17,047,093 | 1.46 | 13344.0 |
| INDV | REDUCED | INDIVIOR PHARMACEUTICALS INC | COM | 45579U109 | 16,461,564 | 1.41 | 401208.0 |
| MRK | NEW | MERCK & CO INC | COM | 58933Y105 | 16,334,663 | 1.4 | 127118.0 |
| CYTK | NEW | CYTOKINETICS INC | COM NEW | 23282W605 | 16,329,730 | 1.4 | 191686.0 |
| - | LANTHEUS HLDGS INC | COM | 516544103 | 16,241,949 | 1.39 | 146403.0 | |
| - | CENTENE CORP DEL | COM | 15135B101 | 15,974,773 | 1.37 | 248867.0 | |
| - | COOPER COS INC | COM | 216648501 | 15,840,022 | 1.36 | 220890.0 | |
| MDGL | REDUCED | MADRIGAL PHARMACEUTICALS INC | COM | 558868105 | 15,739,615 | 1.35 | 29313.0 |
| - | ACADIA HEALTHCARE COMPANY IN | COM | 00404A109 | 15,501,301 | 1.33 | 524934.0 | |
| ORKA | REDUCED | ORUKA THERAPEUTICS INC | COM | 687604108 | 15,115,375 | 1.3 | 158825.0 |
| OSCR | ADDED | OSCAR HEALTH INC | CL A | 687793109 | 14,802,336 | 1.27 | 519016.0 |
| TMO | ADDED | THERMO FISHER SCIENTIFIC INC | COM | 883556102 | 14,286,755 | 1.23 | 28496.0 |
| CVS | NEW | CVS HEALTH CORP | COM | 126650100 | 14,219,927 | 1.22 | 137457.0 |
| - | MERIT MED SYS INC | COM | 589889104 | 13,662,615 | 1.17 | 197038.0 | |
| - | PRAXIS PRECISION MEDICINES I | COM NEW | 74006W207 | 12,914,524 | 1.11 | 38575.0 | |
| CLDX | ADDED | CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 | 12,753,765 | 1.09 | 342751.0 |
| NVO | ADDED | NOVO-NORDISK A S | ADR | 670100205 | 12,704,867 | 1.09 | 265016.0 |
| - | INTEGER HLDGS CORP | COM | 45826H109 | 11,837,218 | 1.02 | 126669.0 | |
| - | DIANTHUS THERAPEUTICS INC | COM | 252828108 | 11,816,721 | 1.01 | 121222.0 | |
| DFTX | ADDED | DEFINIUM THERAPEUTICS INC | COM SHS | 24477V105 | 11,713,901 | 1.01 | 249020.0 |
| GILD | NEW | GILEAD SCIENCES INC | COM | 375558103 | 11,479,000 | 0.98 | 90858.0 |
| RYTM | REDUCED | RHYTHM PHARMACEUTICALS INC | COM | 76243J105 | 11,275,097 | 0.97 | 101550.0 |
| - | SCHEIN HENRY INC | COM | 806407102 | 11,227,009 | 0.96 | 134423.0 | |
| - | ARROWHEAD PHARMACEUTICALS IN | COM | 04280A100 | 10,732,177 | 0.92 | 131667.0 | |
| TNGX | REDUCED | TANGO THERAPEUTICS INC | COM | 87583X109 | 10,192,229 | 0.87 | 326047.0 |
| TFX | NEW | TELEFLEX INCORPORATED | COM | 879369106 | 10,103,786 | 0.87 | 79708.0 |
| VKTX | REDUCED | VIKING THERAPEUTICS INC | COM | 92686J106 | 9,960,423 | 0.85 | 255330.0 |
| - | BRIGHTSPRING HEALTH SVCS INC | COM | 10950A106 | 9,897,082 | 0.85 | 141914.0 | |
| VERA | ADDED | VERA THERAPEUTICS INC | CL A | 92337R101 | 9,624,241 | 0.83 | 224289.0 |
| ROIV | ADDED | ROIVANT SCIENCES LTD | SHS | G76279101 | 9,484,803 | 0.81 | 268008.0 |
| CGON | REDUCED | CG ONCOLOGY INC | COM | 156944100 | 9,114,720 | 0.78 | 128286.0 |
| AMRX | REDUCED | AMNEAL PHARMACEUTICALS INC | COM STK CL A | 03168L105 | 8,321,177 | 0.71 | 480715.0 |
| EPRX | ADDED | EUPRAXIA PHARMACEUTICALS INC | COM | 29842P105 | 8,002,469 | 0.69 | 1210661.0 |
| COR | NEW | CENCORA INC | COM | 03073E105 | 7,951,738 | 0.68 | 28100.0 |
| IRTC | NEW | IRHYTHM HOLDINGS INC | COM | 450056106 | 7,755,064 | 0.67 | 65196.0 |
| KOD | ADDED | KODIAK SCIENCES INC | COM | 50015M109 | 7,531,552 | 0.65 | 193315.0 |
| ABT | REDUCED | ABBOTT LABORATORIES | COM | 002824100 | 7,461,550 | 0.64 | 82230.0 |
| - | WEST PHARMACEUTICAL SVSC INC | COM | 955306105 | 7,443,147 | 0.64 | 20733.0 | |
| TAK | NEW | TAKEDA PHARMACEUTICAL CO LTD | SPONSORED ADS | 874060205 | 7,120,093 | 0.61 | 444173.0 |
| HNGE | NEW | HINGE HEALTH INC | CL A | 433313103 | 6,877,380 | 0.59 | 82860.0 |
| ARQT | NEW | ARCUTIS BIOTHERAPEUTICS INC | COM | 03969K108 | 6,347,049 | 0.54 | 242069.0 |
| - | INTEGRA LIFESCIENCES HLDGS C | COM NEW | 457985208 | 6,263,478 | 0.54 | 348746.0 | |
| ILMN | ADDED | ILLUMINA INC | COM | 452327109 | 6,161,083 | 0.53 | 35040.0 |
| - | MEIRAGTX HLDGS PLC | COM | G59665102 | 6,150,914 | 0.53 | 455286.0 | |
| OCS | NEW | OCULIS HOLDING AG | ORDINARY SHARES | H5870P102 | 6,047,903 | 0.52 | 436042.0 |
| NTRA | REDUCED | NATERA INC | COM | 632307104 | 5,992,802 | 0.51 | 22077.0 |
| - | ABIVAX SA | SPONSORED ADS | 00370M103 | 5,765,361 | 0.49 | 43264.0 | |
| - | CENTENE CORP DEL | COM | 15135B101 | 5,661,558 | 0.49 | 88200.0 | |
| GH | NEW | GUARDANT HEALTH INC | COM | 40131M109 | 5,506,251 | 0.47 | 36701.0 |
| CELC | NEW | CELCUITY INC | COM | 15102K100 | 5,456,456 | 0.47 | 52155.0 |
| BLTE | REDUCED | BELITE BIO INC | SPONSORED ADS | 07782B104 | 5,359,140 | 0.46 | 34803.0 |
| GPCR | REDUCED | STRUCTURE THERAPEUTICS INC | SPONSORED ADS | 86366E106 | 4,913,489 | 0.42 | 91550.0 |
| RCUS | NEW | ARCUS BIOSCIENCES INC | COM | 03969F109 | 4,690,137 | 0.4 | 152129.0 |
| - | CHARLES RIV LABS INTL INC | COM | 159864107 | 4,251,632 | 0.36 | 18747.0 | |
| ELAN | NEW | ELANCO ANIMAL HEALTH INC | COM | 28414H103 | 4,244,954 | 0.36 | 172489.0 |
| ARGX | REDUCED | ARGENX SE | SPONSORED ADR | 04016X101 | 4,158,265 | 0.36 | 4482.0 |
| - | BIO RAD LABS INC | CL A | 090572207 | 4,109,072 | 0.35 | 13995.0 | |
| SYRE | NEW | SPYRE THERAPEUTICS INC | COM NEW | 00773J202 | 4,103,145 | 0.35 | 46217.0 |
| MBX | REDUCED | MBX BIOSCIENCES INC | COM | 55287L101 | 3,917,599 | 0.34 | 70971.0 |
| MIRM | NEW | MIRUM PHARMACEUTICALS INC | COM | 604749101 | 3,691,920 | 0.32 | 31536.0 |
| CGEM | REDUCED | CULLINAN THERAPEUTICS INC | COM | 230031106 | 3,504,369 | 0.3 | 192442.0 |
| CMPS | REDUCED | COMPASS PATHWAYS PLC | SPONSORED ADS | 20451W101 | 3,503,384 | 0.3 | 247589.0 |
| HCA | REDUCED | HCA HEALTHCARE INC | COM | 40412C101 | 3,234,138 | 0.28 | 8295.0 |
| CAPR | REDUCED | CAPRICOR THERAPEUTICS INC | COM NEW | 14070B309 | 2,943,082 | 0.25 | 122221.0 |
| DNLI | NEW | DENALI THERAPEUTICS INC | COM | 24823R105 | 2,596,846 | 0.22 | 100966.0 |
| SNDX | REDUCED | SYNDAX PHARMACEUTICALS INC | COM | 87164F105 | 2,588,705 | 0.22 | 118422.0 |
| AMLX | REDUCED | AMYLYX PHARMACEUTICALS INC | COM | 03237H101 | 2,580,852 | 0.22 | 143700.0 |
| TARS | REDUCED | TARSUS PHARMACEUTICALS INC | COM | 87650L103 | 2,554,042 | 0.22 | 40579.0 |
| - | OUTSET MED INC | COM NEW | 690145206 | 2,514,767 | 0.22 | 582122.0 | |
| OMDA | NEW | OMADA HEALTH INC | COM | 68170A108 | 2,512,002 | 0.22 | 114442.0 |
| ERAS | NEW | ERASCA INC | COM | 29479A108 | 2,456,492 | 0.21 | 134088.0 |
| COR | NEW | CENCORA INC | COM | 03073E105 | 2,089,807 | 0.18 | 7385.0 |
| BCRX | NEW | BIOCRYST PHARMACEUTICALS INC | COM | 09058V103 | 2,073,570 | 0.18 | 207357.0 |
| OMCL | NEW | OMNICELL COM | COM | 68213N109 | 2,036,141 | 0.17 | 49040.0 |
| CVRX | NEW | CVRX INC | COM | 126638105 | 1,899,600 | 0.16 | 369572.0 |
| HIMS | NEW | HIMS & HERS HEALTH INC | COM CL A | 433000106 | 1,714,570 | 0.15 | 49454.0 |
| MLYS | REDUCED | MINERALYS THERAPEUTICS INC | COM | 603170101 | 1,684,038 | 0.14 | 62418.0 |
| TECX | REDUCED | TECTONIC THERAPEUTIC INC | COM | 878972108 | 1,568,566 | 0.13 | 45631.0 |
| - | UNIQURE NV | SHS | N90064101 | 1,215,800 | 0.1 | 26396.0 | |
| RZLT | REDUCED | REZOLUTE INC | COM NEW | 76200L309 | 661,903 | 0.06 | 127289.0 |
| CRBU | REDUCED | CARIBOU BIOSCIENCES INC | COM | 142038108 | 624,249 | 0.05 | 354687.0 |
Quarterly portfolios
| Period | Filed | Value ($) | Positions | Vol % | Beta | Max DD % |
|---|---|---|---|---|---|---|
| 2026-06-30 | 2026-08-14 | 1,165,441,614 | 98 | 10.887039 | 0.376143 | 15.034478 |
| 2026-03-31 | 2026-05-15 | 1,096,740,595 | 83 | 11.14302 | 0.378618 | 17.077366 |
| 2025-12-31 | 2026-02-17 | 1,003,019,673 | 78 | 12.81165 | 0.460857 | 20.178348 |
| 2025-09-30 | 2025-11-14 | 1,300,512,372 | 72 | 12.697848 | 0.455978 | 19.036576 |
| 2025-03-31 | 2025-05-15 | 1,377,290,641 | 66 | 13.037593 | 0.474125 | 19.380953 |
| 2024-12-31 | 2025-02-14 | 1,613,565,785 | 83 | 11.179412 | 0.422571 | 17.269798 |