Catalio Capital Management, LP
CIK 0001958125
Annualised vol
10.750457%
Beta
0.305027
HHI
449.083877
Top-10 weight
56.717536%
VaR 95%
0.989237%
VaR 99%
1.758977%
Max drawdown
14.785782%
Matched value
84.235771%
Returns of reported holdings
Loading returns…
Position changes vs prior quarter
What the latest 13F shows bought and sold against the quarter before, by share count.
| Ticker | Change | Shares now | Shares before | Share change % | Value now ($) |
|---|---|---|---|---|---|
| JNJ | NEW | 138,946 | - | - | 35,288,116 |
| GILD | ADDED | 269,309 | 163,905 | 64.31% | 34,024,499 |
| BBIO | ADDED | 455,041 | 432,014 | 5.33% | 33,891,454 |
| SNDX | ADDED | 1,215,698 | 1,043,670 | 16.48% | 26,575,158 |
| DFTX | REDUCED | 562,672 | 1,037,984 | -45.79% | 26,468,091 |
| BMY | REDUCED | 412,961 | 420,727 | -1.85% | 23,794,813 |
| PBLS | NEW | 824,043 | - | - | 22,554,057 |
| NTRA | ADDED | 82,181 | 70,907 | 15.9% | 22,308,032 |
| INCY | ADDED | 191,627 | 182,101 | 5.23% | 21,722,837 |
| SEPN | ADDED | 536,152 | 294,360 | 82.14% | 17,955,730 |
| MLYS | ADDED | 648,722 | 439,041 | 47.76% | 17,502,520 |
| HTFL | ADDED | 583,055 | 403,588 | 44.47% | 17,106,834 |
| CRVS | ADDED | 1,080,888 | 891,933 | 21.18% | 16,148,467 |
| GPCR | ADDED | 276,550 | 255,379 | 8.29% | 14,842,438 |
| PTGX | NEW | 106,799 | - | - | 13,091,421 |
| IRON | ADDED | 159,384 | 122,978 | 29.6% | 11,657,346 |
| EW | REDUCED | 124,778 | 144,607 | -13.71% | 11,287,418 |
| AXSM | NEW | 43,182 | - | - | 10,569,658 |
| KLRA | NEW | 468,750 | - | - | 10,326,563 |
| KPTI | ADDED | 940,855 | 897,709 | 4.81% | 9,192,153 |
| ODTX | NEW | 457,839 | - | - | 8,566,168 |
| ASND | REDUCED | 31,759 | 129,111 | -75.4% | 8,470,760 |
| KARD | NEW | 312,500 | - | - | 7,453,125 |
| ELDN | ADDED | 1,695,071 | 1,639,816 | 3.37% | 6,678,580 |
| MANE | REDUCED | 45,856 | 173,582 | -73.58% | 5,637,537 |
| DYN | REDUCED | 244,929 | 282,954 | -13.44% | 5,439,873 |
| GUTS | ADDED | 6,168,749 | 5,491,866 | 12.33% | 4,900,454 |
| TARA | REDUCED | 520,148 | 580,024 | -10.32% | 1,986,965 |
| HYPR | UNCHANGED | 1,320,041 | 1,320,041 | 0.0% | 1,782,055 |
| MGX | UNCHANGED | 528,993 | 528,993 | 0.0% | 629,502 |
| FTH | NEW | 14,718 | - | - | 367,950 |
| BSX | CLOSED OUT | 0 | 299,318 | -100.0% | 0 |
| PHAT | CLOSED OUT | 0 | 247,767 | -100.0% | 0 |
| CYTK | CLOSED OUT | 0 | 215,501 | -100.0% | 0 |
| TYRA | CLOSED OUT | 0 | 67,285 | -100.0% | 0 |
| SUPN | CLOSED OUT | 0 | 62,019 | -100.0% | 0 |
Holdings (latest quarter)
| Ticker | Change | Issuer | Class | CUSIP | Value ($) | Weight % | Shares |
|---|---|---|---|---|---|---|---|
| - | AVALYN PHARMACEUTICALS INC | COM SHS | 05348Y105 | 55,168,324 | 10.37 | 1675830.0 | |
| JNJ | NEW | JOHNSON & JOHNSON | COM | 478160104 | 35,288,116 | 6.63 | 138946.0 |
| GILD | ADDED | GILEAD SCIENCES INC | COM | 375558103 | 34,024,499 | 6.39 | 269309.0 |
| BBIO | ADDED | BRIDGEBIO PHARMA INC | COM | 10806X102 | 33,891,454 | 6.37 | 455041.0 |
| SNDX | ADDED | SYNDAX PHARMACEUTICALS INC | COM | 87164F105 | 26,575,158 | 4.99 | 1215698.0 |
| DFTX | REDUCED | DEFINIUM THERAPEUTICS INC | COM SHS | 24477V105 | 26,468,091 | 4.97 | 562672.0 |
| BMY | REDUCED | BRISTOL-MYERS SQUIBB CO | COM | 110122108 | 23,794,813 | 4.47 | 412961.0 |
| PBLS | NEW | PARABILIS MEDICINES INC | COM | 698955101 | 22,554,057 | 4.24 | 824043.0 |
| NTRA | ADDED | NATERA INC | COM | 632307104 | 22,308,032 | 4.19 | 82181.0 |
| INCY | ADDED | INCYTE CORP | COM | 45337C102 | 21,722,837 | 4.08 | 191627.0 |
| SEPN | ADDED | SEPTERNA INC | COM | 81734D104 | 17,955,730 | 3.37 | 536152.0 |
| MLYS | ADDED | MINERALYS THERAPEUTICS INC | COM | 603170101 | 17,502,520 | 3.29 | 648722.0 |
| HTFL | ADDED | HEARTFLOW INC | COM | 42238D107 | 17,106,834 | 3.21 | 583055.0 |
| CRVS | ADDED | CORVUS PHARMACEUTICALS INC | COM | 221015100 | 16,148,467 | 3.03 | 1080888.0 |
| GPCR | ADDED | STRUCTURE THERAPEUTICS INC | SPONSORED ADS | 86366E106 | 14,842,438 | 2.79 | 276550.0 |
| PTGX | NEW | PROTAGONIST THERAPEUTICS INC | COM | 74366E102 | 13,091,421 | 2.46 | 106799.0 |
| IRON | ADDED | DISC MEDICINE INC | COM | 254604101 | 11,657,346 | 2.19 | 159384.0 |
| EW | REDUCED | EDWARDS LIFESCIENCES CORP | COM | 28176E108 | 11,287,418 | 2.12 | 124778.0 |
| AXSM | NEW | AXSOME THERAPEUTICS INC. | COM | 05464T104 | 10,569,658 | 1.99 | 43182.0 |
| - | ULTRAGENYX PHARMACEUTICAL IN | COM | 90400D108 | 10,559,654 | 1.98 | 316252.0 | |
| KLRA | NEW | KAILERA THERAPEUTICS INC | COMMON STOCK | 482931102 | 10,326,563 | 1.94 | 468750.0 |
| KPTI | ADDED | KARYOPHARM THERAPEUTICS INC | COM NEW | 48576U205 | 9,192,153 | 1.73 | 940855.0 |
| ODTX | NEW | ODYSSEY THERAPEUTICS INC | COMMON STOCK | 67613T104 | 8,566,168 | 1.61 | 457839.0 |
| ASND | REDUCED | ASCENDIS PHARMA A/S | ORD SHS | K08588103 | 8,470,760 | 1.59 | 31759.0 |
| KARD | NEW | KARDIGAN INC | COM | 485925101 | 7,453,125 | 1.4 | 312500.0 |
| ELDN | ADDED | ELEDON PHARMACEUTICALS INC | COM | 28617K101 | 6,678,580 | 1.26 | 1695071.0 |
| - | 4D MOLECULAR THERAPEUTICS IN | COM | 35104E100 | 6,267,678 | 1.18 | 471254.0 | |
| MANE | REDUCED | VERADERMICS INC | COMMON STOCK | 922967104 | 5,637,537 | 1.06 | 45856.0 |
| DYN | REDUCED | DYNE THERAPEUTICS INC | COM | 26818M108 | 5,439,873 | 1.02 | 244929.0 |
| GUTS | ADDED | FRACTYL HEALTH INC | COM | 35168W103 | 4,900,454 | 0.92 | 6168749.0 |
| - | IMMUNOCORE HLDGS PLC | ADS | 45258D105 | 4,700,429 | 0.88 | 148045.0 | |
| - | DIANTHUS THERAPEUTICS INC | COM | 252828108 | 3,211,089 | 0.6 | 32941.0 | |
| - | BRIDGEBIO ONCOLOGY THERAPEUT | COM NEW | 107924102 | 2,426,261 | 0.46 | 318407.0 | |
| TARA | REDUCED | PROTARA THERAPEUTICS INC | COM STK | 74365U107 | 1,986,965 | 0.37 | 520148.0 |
| HYPR | UNCHANGED | HYPERFINE INC | COM CL A | 44916K106 | 1,782,055 | 0.33 | 1320041.0 |
| - | ATAIBECKLEY INC | COM SHS | 04650F101 | 1,037,442 | 0.19 | 196858.0 | |
| MGX | UNCHANGED | METAGENOMI THERAPEUTICS INC | COM | 59102M104 | 629,502 | 0.12 | 528993.0 |
| - | OUTSET MED INC | COM NEW | 690145206 | 510,965 | 0.1 | 118279.0 | |
| FTH | NEW | FAETH THERAPEUTICS INC | COM NEW | 81728A207 | 367,950 | 0.07 | 14718.0 |
Quarterly portfolios
| Period | Filed | Value ($) | Positions | Vol % | Beta | Max DD % |
|---|---|---|---|---|---|---|
| 2026-06-30 | 2026-08-14 | 532,102,416 | 39 | 10.750457 | 0.305027 | 14.785782 |
| 2026-03-31 | 2026-05-15 | 478,704,496 | 41 | 9.80528 | 0.27327 | 13.50044 |
| 2025-12-31 | 2026-02-17 | 565,790,302 | 45 | 9.083037 | 0.301201 | 13.601594 |
| 2025-09-30 | 2025-11-14 | 540,929,537 | 38 | 10.787153 | 0.365325 | 13.303723 |
| 2025-03-31 | 2025-05-15 | 411,104,315 | 37 | 10.994365 | 0.338584 | 13.197218 |
| 2024-12-31 | 2025-02-14 | 457,135,528 | 33 | 9.353271 | 0.29208 | 15.342903 |