Prosight Management, LP
CIK 0001617201
Annualised vol
12.139842%
Beta
0.282633
HHI
626.061239
Top-10 weight
70.725349%
VaR 95%
1.007955%
VaR 99%
2.035892%
Max drawdown
18.00704%
Matched value
89.322285%
Returns of reported holdings
Loading returns…
Position changes vs prior quarter
What the latest 13F shows bought and sold against the quarter before, by share count.
| Ticker | Change | Shares now | Shares before | Share change % | Value now ($) |
|---|---|---|---|---|---|
| LKFT | NEW | 2,043,344 | - | - | 61,259,453 |
| JANX | ADDED | 3,804,481 | 3,550,000 | 7.17% | 58,436,828 |
| NKTR | ADDED | 810,000 | 735,000 | 10.2% | 56,546,100 |
| BSX | ADDED | 1,270,273 | 795,547 | 59.67% | 54,215,252 |
| STTK | ADDED | 5,957,877 | 5,004,439 | 19.05% | 41,347,666 |
| INSM | NEW | 375,609 | - | - | 40,047,432 |
| ALNY | ADDED | 98,080 | 76,000 | 29.05% | 29,525,022 |
| SNDX | ADDED | 1,200,000 | 770,000 | 55.84% | 26,232,000 |
| KURA | REDUCED | 2,021,964 | 3,356,700 | -39.76% | 22,180,945 |
| ALKS | REDUCED | 394,389 | 513,632 | -23.22% | 20,664,012 |
| IRTC | ADDED | 165,500 | 10,000 | 1555.0% | 19,686,225 |
| ZYME | ADDED | 674,434 | 539,049 | 25.12% | 17,629,705 |
| MLYS | NEW | 449,795 | - | - | 12,135,469 |
| ADCT | REDUCED | 7,824,749 | 8,300,000 | -5.73% | 8,372,481 |
| ISRG | ADDED | 17,000 | 4,000 | 325.0% | 6,760,560 |
| PRCT | REDUCED | 268,269 | 1,945,000 | -86.21% | 6,057,514 |
| WGS | REDUCED | 85,500 | 523,463 | -83.67% | 5,869,575 |
| OPCH | NEW | 270,716 | - | - | 5,676,915 |
| OKUR | REDUCED | 978,992 | 2,154,381 | -54.56% | 4,464,204 |
| EBS | REDUCED | 459,952 | 639,118 | -28.03% | 3,854,398 |
| PFE | NEW | 135,366 | - | - | 3,259,613 |
| KIDS | REDUCED | 157,500 | 302,399 | -47.92% | 3,012,975 |
| RCKT | ADDED | 700,000 | 683,856 | 2.36% | 2,394,000 |
| ANTX | REDUCED | 474,638 | 515,754 | -7.97% | 2,297,248 |
| PLRX | REDUCED | 1,370,233 | 1,667,600 | -17.83% | 1,562,066 |
| TECX | REDUCED | 39,731 | 79,872 | -50.26% | 1,365,753 |
| EFOR | NEW | 67,500 | - | - | 1,206,225 |
| RNTX | ADDED | 1,100,000 | 411,600 | 167.25% | 1,144,000 |
| COYA | REDUCED | 170,000 | 420,360 | -59.56% | 994,500 |
| IMRX | REDUCED | 36,861 | 123,409 | -70.13% | 183,936 |
| PHR | CLOSED OUT | 0 | 1,100,000 | -100.0% | 0 |
| SDGR | CLOSED OUT | 0 | 510,578 | -100.0% | 0 |
| ACET | CLOSED OUT | 0 | 250,244 | -100.0% | 0 |
| TBI | CLOSED OUT | 0 | 249,107 | -100.0% | 0 |
| UPB | CLOSED OUT | 0 | 241,123 | -100.0% | 0 |
| RGNX | CLOSED OUT | 0 | 200,000 | -100.0% | 0 |
| ROIV | CLOSED OUT | 0 | 180,000 | -100.0% | 0 |
| IMVT | CLOSED OUT | 0 | 175,825 | -100.0% | 0 |
| OMER | CLOSED OUT | 0 | 174,800 | -100.0% | 0 |
| NVCR | CLOSED OUT | 0 | 50,400 | -100.0% | 0 |
| VKTX | CLOSED OUT | 0 | 45,000 | -100.0% | 0 |
| TMDX | CLOSED OUT | 0 | 5,000 | -100.0% | 0 |
Holdings (latest quarter)
| Ticker | Change | Issuer | Class | CUSIP | Value ($) | Weight % | Shares |
|---|---|---|---|---|---|---|---|
| LKFT | NEW | LAKEFRONT BIOTHERAPEUTICS NV | SPON ADR | 36315X101 | 61,259,453 | 10.56 | 2043344.0 |
| JANX | ADDED | JANUX THERAPEUTICS INC | COM | 47103J105 | 58,436,828 | 10.07 | 3804481.0 |
| NKTR | ADDED | NEKTAR THERAPEUTICS | COM NEW | 640268306 | 56,546,100 | 9.74 | 810000.0 |
| BSX | ADDED | BOSTON SCIENTIFIC CORP | COM | 101137107 | 54,215,252 | 9.34 | 1270273.0 |
| STTK | ADDED | SHATTUCK LABS INC | COM | 82024L103 | 41,347,666 | 7.12 | 5957877.0 |
| INSM | NEW | INSMED INC | COM PAR $.01 | 457669307 | 40,047,432 | 6.9 | 375609.0 |
| ALNY | ADDED | ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 29,525,022 | 5.09 | 98080.0 |
| SNDX | ADDED | SYNDAX PHARMACEUTICALS INC | COM | 87164F105 | 26,232,000 | 4.52 | 1200000.0 |
| KURA | REDUCED | KURA ONCOLOGY INC | COM | 50127T109 | 22,180,945 | 3.82 | 2021964.0 |
| ALKS | REDUCED | ALKERMES PLC | SHS | G01767105 | 20,664,012 | 3.56 | 394389.0 |
| IRTC | ADDED | IRHYTHM HOLDINGS INC | COM | 450056106 | 19,686,225 | 3.39 | 165500.0 |
| - | VEEVA SYS INC | CL A COM | 922475108 | 18,847,314 | 3.25 | 106200.0 | |
| ZYME | ADDED | ZYMEWORKS INC | COM | 98985Y108 | 17,629,705 | 3.04 | 674434.0 |
| - | ABIVAX SA | SPONSORED ADS | 00370M103 | 14,311,324 | 2.47 | 107394.0 | |
| - | CRINETICS PHARMACEUTICALS IN | COM | 22663K107 | 14,020,002 | 2.42 | 374666.0 | |
| MLYS | NEW | MINERALYS THERAPEUTICS INC | COM | 603170101 | 12,135,469 | 2.09 | 449795.0 |
| ADCT | REDUCED | ADC THERAPEUTICS SA | SHS | H0036K147 | 8,372,481 | 1.44 | 7824749.0 |
| - | ICU MED INC | COM | 44930G107 | 7,476,600 | 1.29 | 51000.0 | |
| ISRG | ADDED | INTUITIVE SURGICAL INC | COM NEW | 46120E602 | 6,760,560 | 1.16 | 17000.0 |
| - | CORBUS PHARMACEUTICALS HLDGS | COM NEW | 21833P301 | 6,097,000 | 1.05 | 650000.0 | |
| PRCT | REDUCED | PROCEPT BIOROBOTICS CORP | COM | 74276L105 | 6,057,514 | 1.04 | 268269.0 |
| WGS | REDUCED | GENEDX HOLDINGS CORP | COM CL A | 81663L200 | 5,869,575 | 1.01 | 85500.0 |
| OPCH | NEW | OPTION CARE HEALTH INC | COM NEW | 68404L201 | 5,676,915 | 0.98 | 270716.0 |
| OKUR | REDUCED | ONKURE THERAPEUTICS INC | COM CL A | 68277Q105 | 4,464,204 | 0.77 | 978992.0 |
| EBS | REDUCED | EMERGENT BIOSOLUTIONS INC | COM | 29089Q105 | 3,854,398 | 0.66 | 459952.0 |
| PFE | NEW | PFIZER INC | COM | 717081103 | 3,259,613 | 0.56 | 135366.0 |
| KIDS | REDUCED | ORTHOPEDIATRICS CORP | COM | 68752L100 | 3,012,975 | 0.52 | 157500.0 |
| RCKT | ADDED | ROCKET PHARMACEUTICALS INC | COM | 77313F106 | 2,394,000 | 0.41 | 700000.0 |
| ANTX | REDUCED | AN2 THERAPEUTICS INC | COM | 037326105 | 2,297,248 | 0.4 | 474638.0 |
| PLRX | REDUCED | PLIANT THERAPEUTICS INC | COM | 729139105 | 1,562,066 | 0.27 | 1370233.0 |
| TECX | REDUCED | TECTONIC THERAPEUTIC INC | COM | 878972108 | 1,365,753 | 0.24 | 39731.0 |
| - | MEIRAGTX HLDGS PLC | COM | G59665102 | 1,215,900 | 0.21 | 90000.0 | |
| EFOR | NEW | EVERFORTH INC | COM | 00191U102 | 1,206,225 | 0.21 | 67500.0 |
| RNTX | ADDED | REIN THERAPEUTICS INC | COM NEW | 00887A204 | 1,144,000 | 0.2 | 1100000.0 |
| COYA | REDUCED | COYA THERAPEUTICS INC | COMMON STOCK | 22407B108 | 994,500 | 0.17 | 170000.0 |
| IMRX | REDUCED | IMMUNEERING CORP | CLASS A COM | 45254E107 | 183,936 | 0.03 | 36861.0 |
Quarterly portfolios
| Period | Filed | Value ($) | Positions | Vol % | Beta | Max DD % |
|---|---|---|---|---|---|---|
| 2026-06-30 | 2026-08-14 | 580,350,212 | 36 | 12.139842 | 0.282633 | 18.00704 |
| 2026-03-31 | 2026-05-15 | 609,819,841 | 46 | 9.975522 | 0.176782 | 16.556645 |
| 2025-12-31 | 2026-02-13 | 483,927,204 | 38 | 7.593326 | 0.140441 | 16.243523 |
| 2025-09-30 | 2025-11-14 | 428,778,629 | 44 | 8.060375 | 0.219964 | 14.253949 |
| 2025-03-31 | 2025-05-15 | 304,343,468 | 38 | 8.940214 | 0.166892 | 16.315074 |
| 2024-12-31 | 2025-02-14 | 361,837,867 | 36 | 9.387902 | 0.165641 | 23.738631 |