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Institutional Holdings

QURE

Ownership Summary

Institutions Holding
217
Total Shares Held
67,348,956
Total Value Held
$1,591,331,294
Quarter
2025-12-31

Active Positions

Increased Positions
2
529,461 shares
Decreased Positions
5
463,963 shares
Held Positions
0
0 shares
New Positions
209
66,355,532 shares
Sold Out Positions
1
2 shares
Institution Shares Value Change % of Portfolio Reported
FRED ALGER MANAGEMENT, LLC 344,878 $8,252,931 New position 2025-12-31
Diamond Hill Capital Management, LLC (Investment Advisor) 17,463 $804,346 ▼ -15,870 0.01% 2026-06-30
SECTORAL ASSET MANAGEMENT INC 30,585 $731,899 New position 2025-12-31
LANARK FINANCIAL, INC. 0 $0 Sold out 2026-06-30
FMR LLC 6,240,936 $149,345,604 New position 2025-12-31
Avoro Capital Advisors LLC 6,150,000 $147,169,500 New position 2025-12-31
SUSQUEHANNA INTERNATIONAL GROUP, LLP 3,968,550 $94,967,402 New position 2025-12-31
RTW INVESTMENTS, LP 3,711,462 $88,815,286 New position 2025-12-31
STATE STREET CORP 3,231,043 $77,318,859 New position 2025-12-31
JPMORGAN CHASE & CO 2,934,626 $70,225,603 New position 2025-12-31
BlackRock, Inc. 1,974,988 $47,261,464 New position 2025-12-31
CITADEL ADVISORS LLC 1,764,900 $42,234,057 New position 2025-12-31
TWO SIGMA INVESTMENTS, LP 1,451,284 $34,729,226 New position 2025-12-31
MPM BioImpact LLC 1,381,628 $33,062,358 New position 2025-12-31
JENNISON ASSOCIATES LLC 1,371,190 $32,812,576 New position 2025-12-31
Tyro Capital Management LLC 1,327,858 $31,775,640 New position 2025-12-31
SUVRETTA CAPITAL MANAGEMENT, LLC 1,216,734 $29,116,445 New position 2025-12-31
GOLDMAN SACHS GROUP INC 1,167,608 $27,940,859 New position 2025-12-31
683 Capital Management, LLC 1,135,050 $27,161,747 New position 2025-12-31
TWO SIGMA ADVISERS, LP 1,110,400 $26,571,872 New position 2025-12-31
VANGUARD GROUP INC 1,051,379 $25,159,500 New position 2025-12-31
Caption Management, LLC 1,029,677 $24,640,171 New position 2025-12-31
Artia Global Partners LP 1,023,539 $24,493,288 New position 2025-12-31
Integral Health Asset Management, LLC 900,000 $21,537,000 New position 2025-12-31
Affinity Asset Advisors, LLC 850,000 $20,340,500 New position 2025-12-31
MILLENNIUM MANAGEMENT LLC 833,605 $19,948,168 New position 2025-12-31
GEODE CAPITAL MANAGEMENT, LLC 776,071 $18,578,179 New position 2025-12-31
Fiera Capital Corp 768,510 $18,390,444 New position 2025-12-31
FRANKLIN RESOURCES INC 746,602 $17,866,186 New position 2025-12-31
ORBIMED ADVISORS LLC 737,400 $17,645,982 New position 2025-12-31
MORGAN STANLEY 716,927 $17,156,063 New position 2025-12-31
Nantahala Capital Management, LLC 699,298 $16,734,201 New position 2025-12-31
Logos Global Management LP 675,000 $16,152,750 New position 2025-12-31
MAVERICK CAPITAL LTD 661,820 $15,837,353 New position 2025-12-31
BARCLAYS PLC 659,790 $15,788,775 New position 2025-12-31
ADAR1 Capital Management, LLC 530,310 $12,690,318 New position 2025-12-31
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. 521,677 $12,483,731 New position 2025-12-31
EVENTIDE ASSET MANAGEMENT, LLC 498,212 $11,922,168 New position 2025-12-31
UBS Group AG 491,454 $11,760,494 New position 2025-12-31
Whitefort Capital Management, LP 459,000 $10,983,870 New position 2025-12-31
Privium Fund Management B.V. 416,270 $9,961,342 New position 2025-12-31
JANE STREET GROUP, LLC 390,900 $9,354,237 New position 2025-12-31
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 362,878 $8,683,671 New position 2025-12-31
READYSTATE ASSET MANAGEMENT LP 361,560 $8,652,131 New position 2025-12-31
DIADEMA PARTNERS LP 346,800 $8,298,924 New position 2025-12-31
BANK OF AMERICA CORP /DE/ 329,525 $7,885,533 ▲ +34,394 2025-12-31
First Turn Management, LLC 321,655 $7,697,204 New position 2025-12-31
Jump Financial, LLC 306,131 $7,325,715 New position 2025-12-31
Boxer Capital Management, LLC 290,000 $6,939,700 ▼ -510,000 2025-12-31
Catalio Capital Management, LP 288,345 $6,900,096 New position 2025-12-31
Centiva Capital, LP 268,300 $6,420,419 New position 2025-12-31
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. 258,211 $6,179,000 New position 2025-12-31
Parkman Healthcare Partners LLC 257,382 $6,159,151 New position 2025-12-31
CITIGROUP INC 244,765 $5,857,226 New position 2025-12-31
Freshford Capital Management, LLC 229,613 $5,494,639 New position 2025-12-31
BNP PARIBAS FINANCIAL MARKETS 221,343 $5,296,738 New position 2025-12-31
Voss Capital, LP 210,000 $5,025,300 New position 2025-12-31
Eagle Health Investments LP 205,247 $4,911,561 New position 2025-12-31
Ally Bridge Group (NY) LLC 200,000 $4,786,000 New position 2025-12-31
TUDOR INVESTMENT CORP ET AL 199,936 $4,784,468 ▲ +69,902 2025-12-31
PEAK6 LLC 186,500 $4,462,945 New position 2025-12-31
Sofinnova Investments, Inc. 176,513 $4,223,956 New position 2025-12-31
Squarepoint Ops LLC 176,000 $4,211,680 New position 2025-12-31
NORTHERN TRUST CORP 168,820 $4,039,863 New position 2025-12-31
Rafferty Asset Management, LLC 164,937 $3,946,942 New position 2025-12-31
Alyeska Investment Group, L.P. 151,058 $3,614,818 New position 2025-12-31
NEW YORK STATE COMMON RETIREMENT FUND 147,549 $3,530,848 New position 2025-12-31
D. E. Shaw & Co., Inc. 143,156 $3,425,723 New position 2025-12-31
Walleye Capital LLC 141,896 $3,395,571 New position 2025-12-31
BALYASNY ASSET MANAGEMENT L.P. 135,644 $3,245,961 New position 2025-12-31
SILVERARC CAPITAL MANAGEMENT, LLC 126,047 $3,016,305 New position 2025-12-31
Hudson Bay Capital Management LP 125,500 $3,003,215 ▼ -18,536 2025-12-31
Schonfeld Strategic Advisors LLC 122,529 $2,932,117 New position 2025-12-31
NAN FUNG TRINITY (HK) Ltd 115,494 $2,763,771 New position 2025-12-31
SIMPLEX TRADING, LLC 110,675 $2,648,452 New position 2025-12-31
ENVESTNET ASSET MANAGEMENT INC 99,593 $2,383,260 New position 2025-12-31
Ikarian Capital, LLC 91,060 $2,179,066 New position 2025-12-31
Jefferies Financial Group Inc. 90,542 $2,166,670 New position 2025-12-31
NOMURA HOLDINGS INC 87,984 $2,105,457 New position 2025-12-31
Marex Group plc 85,993 $2,057,812 New position 2025-12-31
ROYAL BANK OF CANADA 85,640 $2,050,000 New position 2025-12-31
Clearline Capital LP 83,681 $2,002,486 New position 2025-12-31
CAPITAL FUND MANAGEMENT S.A. 82,978 $1,985,663 New position 2025-12-31
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 80,249 $1,920,359 New position 2025-12-31
Rhenman & Partners Asset Management AB 79,375 $1,899,444 New position 2025-12-31
Swiss National Bank 79,000 $1,890,470 New position 2025-12-31
Atom Investors LP 78,209 $1,871,541 New position 2025-12-31
MOORE CAPITAL MANAGEMENT, LP 75,000 $1,794,750 New position 2025-12-31
ExodusPoint Capital Management, LP 73,775 $1,765,436 New position 2025-12-31
AMERIPRISE FINANCIAL INC 70,796 $1,694,148 New position 2025-12-31
WELLS FARGO & COMPANY/MN 70,236 $1,680,748 New position 2025-12-31
BOOTHBAY FUND MANAGEMENT, LLC 69,748 $1,669,070 New position 2025-12-31
Eversept Partners, LP 62,820 $1,503,283 New position 2025-12-31
PROFUND ADVISORS LLC 59,463 $1,422,950 New position 2025-12-31
SCHRODER INVESTMENT MANAGEMENT GROUP 55,015 $1,308,257 New position 2025-12-31
Senvest Management, LLC 50,000 $1,196,500 New position 2025-12-31
Walleye Trading LLC 49,757 $1,190,685 New position 2025-12-31
WINTON GROUP Ltd 48,185 $1,153,067 New position 2025-12-31
STIFEL FINANCIAL CORP 45,987 $1,100,470 New position 2025-12-31
Y-Intercept (Hong Kong) Ltd 45,778 $1,095,468 New position 2025-12-31
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 44,250 $1,057,459 New position 2025-12-31
STEMPOINT CAPITAL LP 43,485 $1,040,596 New position 2025-12-31
Engineers Gate Manager LP 43,356 $1,037,509 New position 2025-12-31
Bank of New York Mellon Corp 43,309 $1,036,385 New position 2025-12-31
Tejara Capital Ltd 42,000 $1,005,060 New position 2025-12-31
SIG BROKERAGE, LP 42,000 $1,005,060 New position 2025-12-31
Shay Capital LLC 41,073 $982,877 New position 2025-12-31
J. Goldman & Co LP 40,550 $970,362 New position 2025-12-31
Massar Capital Management, LP 40,529 $969,859 New position 2025-12-31
Headlands Technologies LLC 39,616 $948,011 New position 2025-12-31
PFM Health Sciences, LP 39,499 $945,211 New position 2025-12-31
CI INVESTMENTS INC. 37,841 $905,535 New position 2025-12-31
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 35,947 $860,212 New position 2025-12-31
Cinctive Capital Management LP 35,000 $837,550 New position 2025-12-31
MML INVESTORS SERVICES, LLC 33,937 $812,112 New position 2025-12-31
DIAMOND HILL CAPITAL MANAGEMENT INC 33,333 $797,659 New position 2025-12-31
Creek Drive Management Group LLC 300,000 $779,715 New position 2025-12-31
Legal & General Group Plc 31,964 $764,899 New position 2025-12-31
BIT Capital GmbH 31,614 $756,523 New position 2025-12-31
Birchview Capital, LP 30,789 $736,781 New position 2025-12-31
Havemeyer Place LP 29,655 $709,644 New position 2025-12-31
Pekin Hardy Strauss, Inc. 29,300 $701,149 New position 2025-12-31
VOYA INVESTMENT MANAGEMENT LLC 28,850 $690,381 New position 2025-12-31
Susquehanna Portfolio Strategies, LLC 28,708 $686,982 New position 2025-12-31
SummitTX Capital, L.P. 27,708 $663,052 New position 2025-12-31
DnB Asset Management AS 27,342 $654,294 New position 2025-12-31
MONIMUS CAPITAL MANAGEMENT, LP 25,878 $619,261 New position 2025-12-31
Monaco Asset Management SAM 25,000 $598,250 New position 2025-12-31
Point72 Asset Management, L.P. 24,439 $584,825 New position 2025-12-31
TD ASSET MANAGEMENT INC 23,734 $567,955 New position 2025-12-31
Russell Investments Group, Ltd. 23,707 $567,308 New position 2025-12-31
LPL Financial LLC 21,969 $525,727 New position 2025-12-31
MARSHALL WACE, LLP 21,159 $506,335 New position 2025-12-31
Voleon Capital Management LP 20,243 $484,415 New position 2025-12-31
Burkehill Global Management, LP 20,000 $478,600 New position 2025-12-31
STATE OF WISCONSIN INVESTMENT BOARD 19,390 $464,003 New position 2025-12-31
Zurcher Kantonalbank (Zurich Cantonalbank) 19,007 $454,838 New position 2025-12-31
Clear Harbor Asset Management, LLC 17,900 $428,347 New position 2025-12-31
Militia Capital Partners, LP 17,000 $406,810 ▼ -18,000 2025-12-31
JANUS HENDERSON GROUP PLC 16,900 $404,333 New position 2025-12-31
MANUFACTURERS LIFE INSURANCE COMPANY, THE 16,462 $391,466 New position 2025-12-31
Qsemble Capital Management, LP 15,931 $381,229 New position 2025-12-31
PRELUDE CAPITAL MANAGEMENT, LLC 15,739 $376,634 New position 2025-12-31
Lion Point Capital, LP 14,700 $351,771 New position 2025-12-31
FARALLON CAPITAL MANAGEMENT LLC 14,000 $335,020 ▼ -551,000 2025-12-31
SEI INVESTMENTS CO 13,938 $333,424 New position 2025-12-31
Virtus Investment Advisers, LLC 13,636 $326,309 New position 2025-12-31
Lido Advisors, LLC 5,544 $323,603 New position 2025-12-31
FORA Capital, LLC 13,313 $318,580 New position 2025-12-31
Freestone Grove Partners LP 12,984 $310,707 New position 2025-12-31
Lighthouse Investment Partners, LLC 12,500 $299,125 New position 2025-12-31
Vanguard Personalized Indexing Management, LLC 12,356 $295,679 New position 2025-12-31
Vontobel Holding Ltd. 11,933 $285,557 New position 2025-12-31
Diametric Capital, LP 11,822 $282,900 New position 2025-12-31
Arizona State Retirement System 11,141 $266,604 New position 2025-12-31
Persistent Asset Partners Ltd 11,014 $263,565 New position 2025-12-31
Orion Porfolio Solutions, LLC 10,768 $257,678 New position 2025-12-31
Sassicaia Capital Advisers LLC 10,400 $248,872 New position 2025-12-31
Scientech Research LLC 10,203 $244,158 New position 2025-12-31
China Universal Asset Management Co., Ltd. 10,150 $242,890 New position 2025-12-31
Quinn Opportunity Partners LLC 10,000 $239,300 New position 2025-12-31
ASHFORD CAPITAL MANAGEMENT INC 10,000 $239,300 New position 2025-12-31
DLD Asset Management, LP 10,000 $239,250 New position 2025-12-31
Graham Capital Management, L.P. 9,013 $215,681 New position 2025-12-31
Rangeley Capital, LLC 8,500 $203,405 New position 2025-12-31
Mraz, Amerine & Associates, Inc. 8,495 $203,285 New position 2025-12-31
KLP KAPITALFORVALTNING AS 8,400 $201,012 New position 2025-12-31
Cetera Investment Advisers 8,366 $200,198 New position 2025-12-31
Mitsubishi UFJ Asset Management Co., Ltd. 8,098 $189,412 New position 2025-12-31
US BANCORP \DE\ 6,171 $147,672 New position 2025-12-31
Mirae Asset Global Investments Co., Ltd. 6,054 $144,872 New position 2025-12-31
Quantbot Technologies LP 5,444 $130,275 New position 2025-12-31
Activest Wealth Management 5,000 $119,650 New position 2025-12-31
Bellevue Group AG 4,763 $113,979 New position 2025-12-31
DEUTSCHE BANK AG\ 4,621 $110,581 New position 2025-12-31
Knott David M Jr 4,000 $95,720 New position 2025-12-31
Ensign Peak Advisors, Inc 3,650 $87,345 New position 2025-12-31
IFP Advisors, Inc 1,989 $47,597 New position 2025-12-31
Smartleaf Asset Management LLC 2,000 $47,560 New position 2025-12-31
GF FUND MANAGEMENT CO. LTD. 1,223 $29,266 New position 2025-12-31
Torren Management, LLC 1,169 $27,974 New position 2025-12-31
CIBC Private Wealth Group LLC 850 $20,341 New position 2025-12-31
Parallel Advisors, LLC 848 $20,293 New position 2025-12-31
COMERICA BANK 637 $15,246 New position 2025-12-31
OSAIC HOLDINGS, INC. 587 $14,046 New position 2025-12-31
JONES FINANCIAL COMPANIES LLLP 418 $10,003 New position 2025-12-31
HRT FINANCIAL LP 310,050 $7,419 New position 2025-12-31
SBI Securities Co., Ltd. 280 $6,700 New position 2025-12-31
Steward Partners Investment Advisory, LLC 250 $5,983 New position 2025-12-31
Rockefeller Capital Management L.P. 247 $5,911 New position 2025-12-31
PRICE T ROWE ASSOCIATES INC /MD/ 208,646 $4,994 New position 2025-12-31
UMB Bank, n.a. 200 $4,786 New position 2025-12-31
ENTRUST FINANCIAL LLC 190 $4,547 New position 2025-12-31
QUADRANT CAPITAL GROUP LLC 187 $4,475 New position 2025-12-31
Allworth Financial LP 174 $4,164 New position 2025-12-31
State of Wyoming 161 $3,853 New position 2025-12-31
EverSource Wealth Advisors, LLC 109 $2,608 New position 2025-12-31
Tower Research Capital LLC (TRC) 76 $1,819 New position 2025-12-31
ALGERT GLOBAL LLC 72,150 $1,727 New position 2025-12-31
Transamerica Financial Advisors, LLC 71 $1,699 New position 2025-12-31
Global Retirement Partners, LLC 67 $1,603 New position 2025-12-31
Greenline Wealth Management LLC 52 $1,244 New position 2025-12-31
Cape Investment Advisory, Inc. 40 $957 New position 2025-12-31
CULLEN/FROST BANKERS, INC. 34 $814 New position 2025-12-31
MAI Capital Management 28 $671 New position 2025-12-31
Handelsbanken Fonder AB 14,900 $357 New position 2025-12-31
WPG Advisers, LLC 10 $239 New position 2025-12-31
Larson Financial Group LLC 8 $191 New position 2025-12-31
Arax Advisory Partners 6 $144 New position 2025-12-31
MONTAG A & ASSOCIATES INC 5 $118 New position 2025-12-31
FIRST HORIZON CORP 3 $72 New position 2025-12-31
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO 3 $72 New position 2025-12-31
HUNTINGTON NATIONAL BANK 2 $48 New position 2025-12-31
NBC SECURITIES, INC. 2 $47 New position 2025-12-31
CWM, LLC 494 $12 New position 2025-12-31
Daiwa Securities Group Inc. 158 $4 New position 2025-12-31
Motiv8 Investments LLC 45 $1 New position 2025-12-31