Spruce Street Capital LP
CIK 0002050194
Annualised vol
12.499868%
Beta
0.096078
HHI
625.755008
Top-10 weight
70.236261%
VaR 95%
1.083035%
VaR 99%
2.576323%
Max drawdown
39.144017%
Matched value
87.718191%
Returns of reported holdings
Loading returns…
Position changes vs prior quarter
What the latest 13F shows bought and sold against the quarter before, by share count.
| Ticker | Change | Shares now | Shares before | Share change % | Value now ($) |
|---|---|---|---|---|---|
| KNSA | NEW | 918,070 | - | - | 58,710,577 |
| RLAY | UNCHANGED | 2,984,125 | 2,984,125 | 0.0% | 55,832,979 |
| LBRX | UNCHANGED | 1,376,159 | 1,376,159 | 0.0% | 44,663,240 |
| RLMD | ADDED | 6,391,328 | 6,262,114 | 2.06% | 44,227,990 |
| ANRO | ADDED | 1,353,047 | 1,325,210 | 2.1% | 35,706,910 |
| ALKS | ADDED | 543,876 | 317,992 | 71.03% | 28,496,383 |
| SVRA | ADDED | 3,452,576 | 3,383,175 | 2.05% | 21,267,868 |
| PCVX | ADDED | 306,047 | 245,709 | 24.56% | 17,790,512 |
| ELVN | UNCHANGED | 329,006 | 329,006 | 0.0% | 16,697,055 |
| ENTA | NEW | 1,088,731 | - | - | 15,873,698 |
| CATX | ADDED | 3,693,931 | 2,627,107 | 40.61% | 12,596,305 |
| ALMS | UNCHANGED | 392,574 | 392,574 | 0.0% | 11,047,032 |
| IPSC | UNCHANGED | 4,059,054 | 4,059,054 | 0.0% | 9,944,682 |
| NERV | NEW | 1,655,500 | - | - | 9,188,025 |
| SABS | NEW | 2,198,502 | - | - | 8,574,158 |
| ANTX | UNCHANGED | 1,661,073 | 1,661,073 | 0.0% | 8,039,593 |
| ERAS | UNCHANGED | 422,543 | 422,543 | 0.0% | 7,740,988 |
| IKT | NEW | 3,581,603 | - | - | 7,270,654 |
| RACC | NEW | 500,000 | - | - | 5,350,000 |
| HLXC | UNCHANGED | 500,000 | 500,000 | 0.0% | 5,320,000 |
| ZLAB | NEW | 279,110 | - | - | 5,303,090 |
| LXEO | UNCHANGED | 928,593 | 928,593 | 0.0% | 4,322,600 |
| ALEC | UNCHANGED | 2,101,068 | 2,101,068 | 0.0% | 4,223,147 |
| LONA | UNCHANGED | 393,701 | 393,701 | 0.0% | 3,618,112 |
| CRVS | NEW | 231,585 | - | - | 3,459,880 |
| JATT | NEW | 160,000 | - | - | 1,817,600 |
| MAZE | CLOSED OUT | 0 | 200,000 | -100.0% | 0 |
Holdings (latest quarter)
| Ticker | Change | Issuer | Class | CUSIP | Value ($) | Weight % | Shares |
|---|---|---|---|---|---|---|---|
| KNSA | NEW | KINIKSA PHARMACEUTICALS INTL | ORD SHS CL A | G52694109 | 58,710,577 | 11.52 | 918070.0 |
| RLAY | UNCHANGED | RELAY THERAPEUTICS INC | COM | 75943R102 | 55,832,979 | 10.95 | 2984125.0 |
| LBRX | UNCHANGED | LB PHARMACEUTICALS INC | COM SHS | 50180M108 | 44,663,240 | 8.76 | 1376159.0 |
| RLMD | ADDED | RELMADA THERAPEUTICS INC | COM | 75955J402 | 44,227,990 | 8.68 | 6391328.0 |
| ANRO | ADDED | ALTO NEUROSCIENCE INC | COM SHS | 02157Q109 | 35,706,910 | 7.01 | 1353047.0 |
| - | DIANTHUS THERAPEUTICS INC | COM | 252828108 | 34,587,464 | 6.79 | 354816.0 | |
| ALKS | ADDED | ALKERMES PLC | SHS | G01767105 | 28,496,383 | 5.59 | 543876.0 |
| SVRA | ADDED | SAVARA INC | COM | 805111101 | 21,267,868 | 4.17 | 3452576.0 |
| PCVX | ADDED | VAXCYTE INC | COM | 92243G108 | 17,790,512 | 3.49 | 306047.0 |
| ELVN | UNCHANGED | ENLIVEN THERAPEUTICS INC | COM | 29337E102 | 16,697,055 | 3.28 | 329006.0 |
| ENTA | NEW | ENANTA PHARMACEUTICALS INC | COM | 29251M106 | 15,873,698 | 3.11 | 1088731.0 |
| CATX | ADDED | PERSPECTIVE THERAPEUTICS INC | COM NEW | 46489V302 | 12,596,305 | 2.47 | 3693931.0 |
| - | INFLARX NV | COM | N44821101 | 11,988,924 | 2.35 | 5352198.0 | |
| - | SURROZEN INC | COM NEW | 86889P208 | 11,211,438 | 2.2 | 432040.0 | |
| ALMS | UNCHANGED | ALUMIS INC | COM | 022307102 | 11,047,032 | 2.17 | 392574.0 |
| IPSC | UNCHANGED | CENTURY THERAPEUTICS INC | COM | 15673T100 | 9,944,682 | 1.95 | 4059054.0 |
| NERV | NEW | MINERVA NEUROSCIENCES INC | COM NEW | 603380205 | 9,188,025 | 1.8 | 1655500.0 |
| SABS | NEW | SAB BIOTHERAPEUTICS INC | COM NEW | 78397T202 | 8,574,158 | 1.68 | 2198502.0 |
| ANTX | UNCHANGED | AN2 THERAPEUTICS INC | COM | 037326105 | 8,039,593 | 1.58 | 1661073.0 |
| ERAS | UNCHANGED | ERASCA INC | COM | 29479A108 | 7,740,988 | 1.52 | 422543.0 |
| IKT | NEW | INHIBIKASE THERAPEUTICS INC | COM NEW | 45719W205 | 7,270,654 | 1.43 | 3581603.0 |
| RACC | NEW | RESEARCH ALLIANCE CORP III | ORD SHS CL A | G75226103 | 5,350,000 | 1.05 | 500000.0 |
| HLXC | UNCHANGED | HELIX ACQUISITION CORP III | USD CL A ORD SHS | G4444S107 | 5,320,000 | 1.04 | 500000.0 |
| ZLAB | NEW | ZAI LAB LTD | ADR | 98887Q104 | 5,303,090 | 1.04 | 279110.0 |
| - | ACHIEVE LIFE SCIENCE INC | COM | 004468500 | 4,810,240 | 0.94 | 736637.0 | |
| LXEO | UNCHANGED | LEXEO THERAPEUTICS INC | COM | 52886X107 | 4,322,600 | 0.85 | 928593.0 |
| ALEC | UNCHANGED | ALECTOR INC | COM | 014442107 | 4,223,147 | 0.83 | 2101068.0 |
| LONA | UNCHANGED | LEONABIO INC | COM | 04746L203 | 3,618,112 | 0.71 | 393701.0 |
| CRVS | NEW | CORVUS PHARMACEUTICALS INC | COM | 221015100 | 3,459,880 | 0.68 | 231585.0 |
| JATT | NEW | JATT II ACQUISITION CORP | ORD SHS | G50765109 | 1,817,600 | 0.36 | 160000.0 |
Quarterly portfolios
| Period | Filed | Value ($) | Positions | Vol % | Beta | Max DD % |
|---|---|---|---|---|---|---|
| 2026-06-30 | 2026-08-13 | 509,681,144 | 30 | 12.499868 | 0.096078 | 39.144017 |
| 2026-03-31 | 2026-05-14 | 415,936,109 | 28 | 11.244937 | 0.074885 | 39.144834 |
| 2025-12-31 | 2026-02-13 | 302,659,606 | 27 | 11.087348 | 0.085448 | 37.545094 |