Octagon Capital Advisors LP
CIK 0001839435
Annualised vol
12.453091%
Beta
0.114384
HHI
824.410988
Top-10 weight
78.538678%
VaR 95%
1.084527%
VaR 99%
2.341415%
Max drawdown
28.181807%
Matched value
71.969262%
Returns of reported holdings
Loading returns…
Position changes vs prior quarter
What the latest 13F shows bought and sold against the quarter before, by share count.
| Ticker | Change | Shares now | Shares before | Share change % | Value now ($) |
|---|---|---|---|---|---|
| DFTX | ADDED | 2,950,000 | 2,440,000 | 20.9% | 138,768,000 |
| COGT | UNCHANGED | 2,350,000 | 2,350,000 | 0.0% | 90,945,000 |
| ALMS | UNCHANGED | 2,830,700 | 2,830,700 | 0.0% | 79,655,898 |
| AVBP | UNCHANGED | 1,971,054 | 1,971,054 | 0.0% | 68,474,416 |
| TSHA | ADDED | 9,693,244 | 8,859,911 | 9.41% | 66,010,992 |
| BIOA | UNCHANGED | 1,748,000 | 1,748,000 | 0.0% | 42,843,480 |
| MIRM | UNCHANGED | 338,900 | 338,900 | 0.0% | 39,675,023 |
| KYMR | REDUCED | 310,000 | 425,000 | -27.06% | 35,547,700 |
| AKTS | UNCHANGED | 960,847 | 960,847 | 0.0% | 30,968,099 |
| XENE | UNCHANGED | 490,000 | 490,000 | 0.0% | 29,576,400 |
| ERAS | NEW | 1,255,000 | - | - | 22,991,600 |
| PALI | UNCHANGED | 10,276,317 | 10,276,317 | 0.0% | 21,477,503 |
| OCUL | REDUCED | 2,075,000 | 3,166,600 | -34.47% | 20,376,500 |
| IRON | UNCHANGED | 270,000 | 270,000 | 0.0% | 19,747,800 |
| SMMT | NEW | 1,250,000 | - | - | 18,212,500 |
| PHVS | ADDED | 456,721 | 165,000 | 176.8% | 15,793,412 |
| ANL | NEW | 934,716 | - | - | 10,749,234 |
| DTIL | REDUCED | 1,350,000 | 2,236,732 | -39.64% | 10,611,000 |
| DBVT | UNCHANGED | 574,200 | 574,200 | 0.0% | 9,416,880 |
| FTH | NEW | 361,010 | - | - | 9,025,250 |
| GYRE | NEW | 954,416 | - | - | 6,289,601 |
| TRVI | REDUCED | 315,000 | 1,485,000 | -78.79% | 5,874,750 |
| UNCY | UNCHANGED | 1,000,000 | 1,000,000 | 0.0% | 4,690,000 |
| CNTX | REDUCED | 3,050,000 | 5,250,000 | -41.9% | 1,689,395 |
| GOSS | UNCHANGED | 7,750,000 | 7,750,000 | 0.0% | 1,275,650 |
| LXEO | CLOSED OUT | 0 | 1,100,000 | -100.0% | 0 |
| CATX | CLOSED OUT | 0 | 791,555 | -100.0% | 0 |
| EVMN | CLOSED OUT | 0 | 143,472 | -100.0% | 0 |
Holdings (latest quarter)
| Ticker | Change | Issuer | Class | CUSIP | Value ($) | Weight % | Shares |
|---|---|---|---|---|---|---|---|
| - | DIANTHUS THERAPEUTICS INC | COM | 252828108 | 179,525,699 | 16.14 | 1841667.0 | |
| DFTX | ADDED | DEFINIUM THERAPEUTICS INC | COM SHS | 24477V105 | 138,768,000 | 12.47 | 2950000.0 |
| - | ABIVAX SA | SPONSORED ADS | 00370M103 | 132,327,180 | 11.89 | 993000.0 | |
| COGT | UNCHANGED | COGENT BIOSCIENCES INC | COM | 19240Q201 | 90,945,000 | 8.17 | 2350000.0 |
| ALMS | UNCHANGED | ALUMIS INC | COM | 022307102 | 79,655,898 | 7.16 | 2830700.0 |
| AVBP | UNCHANGED | ARRIVENT BIOPHARMA INC | COM | 04272N102 | 68,474,416 | 6.15 | 1971054.0 |
| TSHA | ADDED | TAYSHA GENE THERAPIES INC | COM SHS | 877619106 | 66,010,992 | 5.93 | 9693244.0 |
| BIOA | UNCHANGED | BIOAGE LABS INC | COM | 09077V100 | 42,843,480 | 3.85 | 1748000.0 |
| MIRM | UNCHANGED | MIRUM PHARMACEUTICALS INC | COM | 604749101 | 39,675,023 | 3.57 | 338900.0 |
| KYMR | REDUCED | KYMERA THERAPEUTICS INC | COM | 501575104 | 35,547,700 | 3.2 | 310000.0 |
| AKTS | UNCHANGED | AKTIS ONCOLOGY INC | COM | 01021M104 | 30,968,099 | 2.78 | 960847.0 |
| XENE | UNCHANGED | XENON PHARMACEUTICALS INC | COM | 98420N105 | 29,576,400 | 2.66 | 490000.0 |
| ERAS | NEW | ERASCA INC | CALL | 29479A908 | 22,991,600 | 2.07 | 1255000.0 |
| PALI | UNCHANGED | PALISADE BIO INC | COM | 696389402 | 21,477,503 | 1.93 | 1.0276317E7 |
| OCUL | REDUCED | OCULAR THERAPEUTIX INC | COM | 67576A100 | 20,376,500 | 1.83 | 2075000.0 |
| IRON | UNCHANGED | DISC MEDICINE INC | COM | 254604101 | 19,747,800 | 1.78 | 270000.0 |
| SMMT | NEW | SUMMIT THERAPEUTICS INC | COM | 86627T108 | 18,212,500 | 1.64 | 1250000.0 |
| PHVS | ADDED | PHARVARIS N V | COM | N69605108 | 15,793,412 | 1.42 | 456721.0 |
| ANL | NEW | ADLAI NORTYE LTD | SPONSORED ADS | 00704R109 | 10,749,234 | 0.97 | 934716.0 |
| DTIL | REDUCED | PRECISION BIOSCIENCES INC | COM NEW | 74019P207 | 10,611,000 | 0.95 | 1350000.0 |
| DBVT | UNCHANGED | DBV TECHNOLOGIES S A | SPONSORED ADS | 23306J309 | 9,416,880 | 0.85 | 574200.0 |
| FTH | NEW | FAETH THERAPEUTICS INC | COM NEW | 81728A207 | 9,025,250 | 0.81 | 361010.0 |
| GYRE | NEW | GYRE THERAPEUTICS INC | COM | 403783103 | 6,289,601 | 0.57 | 954416.0 |
| TRVI | REDUCED | TREVI THERAPEUTICS INC | COM | 89532M101 | 5,874,750 | 0.53 | 315000.0 |
| UNCY | UNCHANGED | UNICYCIVE THERAPEUTICS INC | COM NEW | 90466Y202 | 4,690,000 | 0.42 | 1000000.0 |
| CNTX | REDUCED | CONTEXT THERAPEUTICS INC | COM | 21077P108 | 1,689,395 | 0.15 | 3050000.0 |
| GOSS | UNCHANGED | GOSSAMER BIO INC | COM | 38341P102 | 1,275,650 | 0.11 | 7750000.0 |
Quarterly portfolios
| Period | Filed | Value ($) | Positions | Vol % | Beta | Max DD % |
|---|---|---|---|---|---|---|
| 2026-06-30 | 2026-08-14 | 1,112,538,962 | 27 | 12.453091 | 0.114384 | 28.181807 |
| 2026-03-31 | 2026-05-15 | 903,605,540 | 29 | 10.009729 | 0.087076 | 23.896736 |
| 2025-12-31 | 2026-02-17 | 823,679,402 | 27 | 10.440058 | 0.089192 | 24.07296 |
| 2025-09-30 | 2025-11-14 | 659,757,896 | 27 | 7.532062 | 0.061204 | 13.379805 |
| 2025-03-31 | 2025-05-16 | 516,795,482 | 35 | 9.787467 | 0.080511 | 18.003903 |
| 2024-12-31 | 2025-02-14 | 607,700,826 | 33 | 8.731919 | 0.158448 | 20.747594 |