Commodore Capital LP
CIK 0001831942
Annualised vol
17.514549%
Beta
0.17295
HHI
621.774617
Top-10 weight
68.176419%
VaR 95%
1.58456%
VaR 99%
3.461891%
Max drawdown
49.277802%
Matched value
98.290494%
Returns of reported holdings
Loading returns…
Position changes vs prior quarter
What the latest 13F shows bought and sold against the quarter before, by share count.
| Ticker | Change | Shares now | Shares before | Share change % | Value now ($) |
|---|---|---|---|---|---|
| RLAY | REDUCED | 12,000,000 | 17,000,000 | -29.41% | 224,520,000 |
| ELVN | UNCHANGED | 3,275,000 | 3,275,000 | 0.0% | 166,206,250 |
| ALKS | REDUCED | 3,000,000 | 4,200,000 | -28.57% | 157,185,000 |
| COGT | ADDED | 3,050,000 | 2,888,007 | 5.61% | 118,035,000 |
| AMLX | UNCHANGED | 5,650,000 | 5,650,000 | 0.0% | 101,474,000 |
| DFTX | UNCHANGED | 2,000,000 | 2,000,000 | 0.0% | 94,080,000 |
| SYRE | REDUCED | 846,786 | 1,912,380 | -55.72% | 75,177,661 |
| ANRO | UNCHANGED | 2,723,196 | 2,723,196 | 0.0% | 71,865,142 |
| TNGX | NEW | 2,250,000 | - | - | 70,335,000 |
| EYPT | ADDED | 4,600,000 | 2,825,000 | 62.83% | 65,780,000 |
| TYRA | REDUCED | 1,875,000 | 2,475,000 | -24.24% | 59,887,500 |
| DMRA | UNCHANGED | 1,939,000 | 1,939,000 | 0.0% | 50,433,390 |
| CLDX | REDUCED | 1,350,000 | 2,696,616 | -49.94% | 50,233,500 |
| PHVS | REDUCED | 1,425,000 | 1,918,970 | -25.74% | 49,276,500 |
| LBRX | UNCHANGED | 1,500,000 | 1,500,000 | 0.0% | 48,682,500 |
| ASMB | ADDED | 1,415,000 | 1,000,000 | 41.5% | 38,884,200 |
| EDIT | NEW | 8,889,000 | - | - | 28,800,360 |
| KYMR | REDUCED | 250,000 | 750,000 | -66.67% | 28,667,500 |
| CATX | UNCHANGED | 6,336,782 | 6,336,782 | 0.0% | 21,608,427 |
| IPSC | UNCHANGED | 8,695,652 | 8,695,652 | 0.0% | 21,304,347 |
| ZURA | UNCHANGED | 3,250,000 | 3,250,000 | 0.0% | 19,175,000 |
| AVTX | ADDED | 1,018,319 | 483,000 | 110.83% | 18,818,535 |
| ANTX | ADDED | 2,933,680 | 2,333,713 | 25.71% | 14,199,011 |
| SABS | REDUCED | 2,870,000 | 4,401,500 | -34.79% | 11,193,000 |
| IKT | UNCHANGED | 5,397,488 | 5,397,488 | 0.0% | 10,956,901 |
| RLMD | ADDED | 1,425,000 | 633,901 | 124.8% | 9,861,000 |
| PEPG | UNCHANGED | 4,475,000 | 4,475,000 | 0.0% | 8,055,000 |
| RACC | NEW | 500,000 | - | - | 5,350,000 |
| HLXC | UNCHANGED | 500,000 | 500,000 | 0.0% | 5,320,000 |
| LONA | UNCHANGED | 464,398 | 464,398 | 0.0% | 4,267,818 |
| VTGN | NEW | 2,788,620 | - | - | 630,228 |
| PALI | CLOSED OUT | 0 | 7,181,062 | -100.0% | 0 |
| ERAS | CLOSED OUT | 0 | 3,175,000 | -100.0% | 0 |
| OCUL | CLOSED OUT | 0 | 2,575,000 | -100.0% | 0 |
| NRIX | CLOSED OUT | 0 | 2,275,000 | -100.0% | 0 |
| CRVS | CLOSED OUT | 0 | 2,258,735 | -100.0% | 0 |
| KPTI | CLOSED OUT | 0 | 1,950,000 | -100.0% | 0 |
| XENE | CLOSED OUT | 0 | 825,000 | -100.0% | 0 |
Holdings (latest quarter)
| Ticker | Change | Issuer | Class | CUSIP | Value ($) | Weight % | Shares |
|---|---|---|---|---|---|---|---|
| RLAY | REDUCED | RELAY THERAPEUTICS INC | COM | 75943R102 | 224,520,000 | 13.37 | 1.2E7 |
| ELVN | UNCHANGED | ENLIVEN THERAPEUTICS INC | COM | 29337E102 | 166,206,250 | 9.9 | 3275000.0 |
| ALKS | REDUCED | ALKERMES PLC | SHS | G01767105 | 157,185,000 | 9.36 | 3000000.0 |
| COGT | ADDED | COGENT BIOSCIENCES INC | COM | 19240Q201 | 118,035,000 | 7.03 | 3050000.0 |
| AMLX | UNCHANGED | AMYLYX PHARMACEUTICALS INC | COM | 03237H101 | 101,474,000 | 6.04 | 5650000.0 |
| DFTX | UNCHANGED | DEFINIUM THERAPEUTICS INC | COM SHS | 24477V105 | 94,080,000 | 5.6 | 2000000.0 |
| SYRE | REDUCED | SPYRE THERAPEUTICS INC | COM NEW | 00773J202 | 75,177,661 | 4.48 | 846786.0 |
| ANRO | UNCHANGED | ALTO NEUROSCIENCE INC | COM SHS | 02157Q109 | 71,865,142 | 4.28 | 2723196.0 |
| TNGX | NEW | TANGO THERAPEUTICS INC | COM | 87583X109 | 70,335,000 | 4.19 | 2250000.0 |
| EYPT | ADDED | EYEPOINT INC | COM NEW | 30233G209 | 65,780,000 | 3.92 | 4600000.0 |
| TYRA | REDUCED | TYRA BIOSCIENCES INC | COM | 90240B106 | 59,887,500 | 3.57 | 1875000.0 |
| DMRA | UNCHANGED | DAMORA THERAPEUTICS INC | COM NEW | 36322Q206 | 50,433,390 | 3.0 | 1939000.0 |
| CLDX | REDUCED | CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 | 50,233,500 | 2.99 | 1350000.0 |
| PHVS | REDUCED | PHARVARIS N V | COM | N69605108 | 49,276,500 | 2.93 | 1425000.0 |
| LBRX | UNCHANGED | LB PHARMACEUTICALS INC | COM SHS | 50180M108 | 48,682,500 | 2.9 | 1500000.0 |
| ASMB | ADDED | ASSEMBLY BIOSCIENCES INC | COM NEW | 045396207 | 38,884,200 | 2.32 | 1415000.0 |
| EDIT | NEW | EDITAS MEDICINE INC | COM | 28106W103 | 28,800,360 | 1.72 | 8889000.0 |
| KYMR | REDUCED | KYMERA THERAPEUTICS INC | COM | 501575104 | 28,667,500 | 1.71 | 250000.0 |
| CATX | UNCHANGED | PERSPECTIVE THERAPEUTICS INC | COM NEW | 46489V302 | 21,608,427 | 1.29 | 6336782.0 |
| IPSC | UNCHANGED | CENTURY THERAPEUTICS INC | COM | 15673T100 | 21,304,347 | 1.27 | 8695652.0 |
| ZURA | UNCHANGED | ZURA BIO LTD | CLASS A ORD SHS | G9TY5A101 | 19,175,000 | 1.14 | 3250000.0 |
| AVTX | ADDED | AVALO THERAPEUTICS INC | COM NEW | 05338F306 | 18,818,535 | 1.12 | 1018319.0 |
| - | INFLARX NV | COM | N44821101 | 16,352,000 | 0.97 | 7300000.0 | |
| ANTX | ADDED | AN2 THERAPEUTICS INC | COM | 037326105 | 14,199,011 | 0.85 | 2933680.0 |
| - | NUVALENT INC | COM | 670703107 | 12,350,000 | 0.74 | 100000.0 | |
| SABS | REDUCED | SAB BIOTHERAPEUTICS INC | COM NEW | 78397T202 | 11,193,000 | 0.67 | 2870000.0 |
| IKT | UNCHANGED | INHIBIKASE THERAPEUTICS INC | COM NEW | 45719W205 | 10,956,901 | 0.65 | 5397488.0 |
| RLMD | ADDED | RELMADA THERAPEUTICS INC | COM | 75955J402 | 9,861,000 | 0.59 | 1425000.0 |
| PEPG | UNCHANGED | PEPGEN INC | COM | 713317105 | 8,055,000 | 0.48 | 4475000.0 |
| RACC | NEW | RESEARCH ALLIANCE CORP III | ORD SHS CL A | G75226103 | 5,350,000 | 0.32 | 500000.0 |
| HLXC | UNCHANGED | HELIX ACQUISITION CORP III | USD CL A ORD SHS | G4444S107 | 5,320,000 | 0.32 | 500000.0 |
| LONA | UNCHANGED | LEONABIO INC | COM | 04746L203 | 4,267,818 | 0.25 | 464398.0 |
| VTGN | NEW | VISTAGEN THERAPEUTICS INC | COM | 92840H400 | 630,228 | 0.04 | 2788620.0 |
Quarterly portfolios
| Period | Filed | Value ($) | Positions | Vol % | Beta | Max DD % |
|---|---|---|---|---|---|---|
| 2026-06-30 | 2026-08-14 | 1,678,964,770 | 33 | 17.514549 | 0.17295 | 49.277802 |
| 2026-03-31 | 2026-05-15 | 1,728,452,370 | 36 | 15.655145 | 0.153612 | 46.168704 |
| 2025-12-31 | 2026-02-17 | 1,502,245,473 | 33 | 13.583053 | 0.131741 | 43.156059 |
| 2025-09-30 | 2025-11-14 | 2,048,436,266 | 37 | 8.633767 | 0.083714 | 27.460328 |
| 2025-03-31 | 2025-05-15 | 1,357,083,846 | 31 | 8.801733 | 0.080398 | 28.496643 |
| 2024-12-31 | 2025-02-14 | 1,364,557,313 | 31 | 9.740083 | 0.08467 | 32.559522 |