ARCH Venture Management, LLC
CIK 0001274403
Annualised vol
14.029875%
Beta
0.098171
HHI
1238.040063
Top-10 weight
99.267334%
VaR 95%
1.097972%
VaR 99%
2.707542%
Max drawdown
36.2385%
Matched value
100.0%
Returns of reported holdings
Loading returns…
Position changes vs prior quarter
What the latest 13F shows bought and sold against the quarter before, by share count.
| Ticker | Change | Shares now | Shares before | Share change % | Value now ($) |
|---|---|---|---|---|---|
| PBLS | NEW | 6,412,780 | - | - | 175,517,789 |
| BEAM | UNCHANGED | 4,540,132 | 4,540,132 | 0.0% | 155,771,929 |
| RAPP | UNCHANGED | 3,728,738 | 3,728,738 | 0.0% | 155,376,512 |
| SPTX | NEW | 6,294,951 | - | - | 136,600,437 |
| ERAS | UNCHANGED | 7,091,557 | 7,091,557 | 0.0% | 129,917,324 |
| VIR | REDUCED | 12,694,163 | 12,916,663 | -1.72% | 129,353,521 |
| MAZE | UNCHANGED | 4,120,053 | 4,120,053 | 0.0% | 122,983,582 |
| LYEL | UNCHANGED | 3,247,162 | 3,247,162 | 0.0% | 45,525,211 |
| GENB | UNCHANGED | 1,944,426 | 1,944,426 | 0.0% | 32,802,467 |
| TXG | UNCHANGED | 217,834 | 217,834 | 0.0% | 8,351,756 |
| BOLD | NEW | 2,694,095 | - | - | 6,735,238 |
| GOSS | UNCHANGED | 8,055,916 | 8,055,916 | 0.0% | 1,326,004 |
| QTTB | CLOSED OUT | 0 | 320,482 | -100.0% | 0 |
Holdings (latest quarter)
| Ticker | Change | Issuer | Class | CUSIP | Value ($) | Weight % | Shares |
|---|---|---|---|---|---|---|---|
| PBLS | NEW | PARABILIS MEDICINES INC | COM | 698955101 | 175,517,789 | 15.95 | 6412780.0 |
| BEAM | UNCHANGED | BEAM THERAPEUTICS INC | COM | 07373V105 | 155,771,929 | 14.16 | 4540132.0 |
| RAPP | UNCHANGED | RAPPORT THERAPEUTICS INC | COM | 75383L102 | 155,376,512 | 14.12 | 3728738.0 |
| SPTX | NEW | SEAPORT THERAPEUTICS INC | COMMON STOCK | 81221K108 | 136,600,437 | 12.42 | 6294951.0 |
| ERAS | UNCHANGED | ERASCA INC | COM | 29479A108 | 129,917,324 | 11.81 | 7091557.0 |
| VIR | REDUCED | VIR BIOTECHNOLOGY INC | COM | 92764N102 | 129,353,521 | 11.76 | 1.2694163E7 |
| MAZE | UNCHANGED | MAZE THERAPEUTICS INC | COM | 578784100 | 122,983,582 | 11.18 | 4120053.0 |
| LYEL | UNCHANGED | LYELL IMMUNOPHARMA INC | COM NEW | 55083R203 | 45,525,211 | 4.14 | 3247162.0 |
| GENB | UNCHANGED | GENERATE BIOMEDICINES INC | COM SHS | 370920100 | 32,802,467 | 2.98 | 1944426.0 |
| TXG | UNCHANGED | 10X GENOMICS INC | CL A COM | 88025U109 | 8,351,756 | 0.76 | 217834.0 |
| BOLD | NEW | BOUNDLESS BIO INC | COM | 10170A100 | 6,735,238 | 0.61 | 2694095.0 |
| GOSS | UNCHANGED | GOSSAMER BIO INC | COM | 38341P102 | 1,326,004 | 0.12 | 8055916.0 |
Quarterly portfolios
| Period | Filed | Value ($) | Positions | Vol % | Beta | Max DD % |
|---|---|---|---|---|---|---|
| 2026-06-30 | 2026-08-14 | 1,100,261,770 | 12 | 14.029875 | 0.098171 | 36.2385 |
| 2026-03-31 | 2026-05-15 | 677,093,705 | 10 | 18.604252 | 0.1248 | 45.697312 |
| 2025-12-31 | 2026-02-17 | 651,681,142 | 9 | 18.277415 | 0.124359 | 46.877378 |
| 2025-09-30 | 2025-11-14 | 492,363,653 | 9 | 18.989329 | 0.130618 | 45.986841 |
| 2025-03-31 | 2025-05-15 | 206,219,148 | 9 | 22.026693 | 0.161021 | 52.386163 |
| 2024-12-31 | 2025-02-14 | 230,217,188 | 9 | 24.746789 | 0.183254 | 53.473014 |